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REVENUE RECOGNITION (Tables)
12 Months Ended
Dec. 31, 2021
REVENUE RECOGNITION.  
Reconciliation of gross product sales to net product sales by each significant category of gross-to-net adjustments

Year ended

(in thousands)

December 31, 2021

Gross product revenue

$

8,172

Gross-to-net adjustments:

Chargebacks and administrative fees

(840)

Trade discounts and allowances

(383)

Government rebates and co-payment assistance

(372)

Sales returns and allowances

(40)

Total gross-to-net adjustments(1)

$

(1,635)

Net product revenue

$

6,537

(1)As of December 31, 2021, approximately $0.4 million of estimated gross-to-net-accruals have been recorded as a reduction of accounts receivable, net and within accounts payable and accrued expenses on the consolidated balance sheets.