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Note 1 - Organization and Summary of Significant Accounting Policies (Details Textual) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Jul. 28, 2023
Mar. 31, 2024
Sep. 30, 2023
Mar. 31, 2023
Dec. 31, 2023
Retained Earnings (Accumulated Deficit)   $ (1,525,068)     $ (1,514,361)
Revenue from Contract with Customer, Excluding Assessed Tax   63,474   $ 7,803  
Cash, Cash Equivalents, and Short-Term Investments   209,800      
Commercialization Agreement With Neuraxpharm [Member]          
License and Collaboration Agreements, One-time, Non-refundable Payment $ 140,000   $ 140,000   $ 140,000
Briumvi Ublituximab [Member]          
Revenue from Contract with Customer, Excluding Assessed Tax   50,500      
Proceeds From Sales Returns   $ 0