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STOCKHOLDERS' EQUITY (Tables)
12 Months Ended
Dec. 31, 2014
Stockholders' Equity Note [Abstract]  
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
The following table summarizes stock option activity for the years ended December 31, 2014 and 2013:
 
 
 
Number
of shares
 
Weighted-
average
exercise price
 
Weighted-
average
Contractual
Term
 
Aggregate
Intrinsic
Value
 
 
 
 
 
 
 
 
(in years)
 
 
 
 
Outstanding at January 1, 2013
 
46,904
 
$
61.08
 
9.44
 
 
 
 
Granted
 
 
 
 
 
 
 
 
 
Exercised
 
 
 
 
 
 
 
 
 
Forfeited
 
(313)
 
 
2,249.85
 
 
 
 
 
 
Expired
 
 
 
 
 
 
 
 
 
Outstanding at December 31, 2013
 
46,591
 
 
46.37
 
8.50
 
$
 
Granted
 
 
 
 
 
 
 
 
 
Exercised
 
(46,000)
 
 
4.40
 
 
 
 
 
 
Forfeited
 
 
 
 
 
 
 
 
 
Expired
 
(397)
 
 
4,457.57
 
 
 
 
 
 
Outstanding at December 31, 2014
 
194
 
$
971.70
 
3.50
 
$
 
 
 
 
 
 
 
 
 
 
 
 
 
Exercisable at December 31, 2014
 
194
 
$
971.70
 
3.50
 
$
 
Schedule of Nonvested Restricted Stock Units Activity [Table Text Block]
Certain employees, directors and consultants have been awarded restricted stock. The restricted stock vesting consists of milestone and time-based vesting. The following table summarizes restricted share activity for the years ended December 31, 2014 and 2013:
 
 
 
Number of Shares
 
Weighted
Average
Grant Date
Fair Value
 
Outstanding at January 1, 2013
 
6,614,243
 
$
4.49
 
Granted
 
944,464
 
 
4.13
 
Vested
 
(523,750)
 
 
2.48
 
Forfeited
 
 
 
 
Outstanding at December 31, 2013
 
7,034,957
 
$
4.60
 
Granted
 
982,793
 
 
13.55
 
Vested
 
(1,616,749)
 
 
6.53
 
Forfeited
 
(1,000)
 
 
6.60
 
Outstanding at December 31, 2014
 
6,400,001
 
$
5.86
 
Schedule Of Warrants Activity [Table Text Block]
The following table summarizes warrant activity for the years ended December 31, 2014 and 2013:
 
 
 
Warrants
 
Weighted-
average
exercise price
 
Aggregate
Intrinsic
Value
 
Outstanding at January 1, 2013
 
6,781,007
 
$
1.58
 
$
14,563,539
 
Issued
 
 
 
 
 
 
 
Exercised
 
(1,018,068)
 
 
2.25
 
 
 
 
Expired
 
(43,992)
 
 
16.26
 
 
 
 
Outstanding at December 31, 2013
 
5,718,947
 
 
1.34
 
$
14,809,030
 
Issued
 
 
 
 
 
 
 
Exercised
 
(1,560,826)
 
 
2.28
 
 
 
 
Expired
 
(9,893)
 
 
20.74
 
 
 
 
Outstanding at December 31, 2014
 
4,148,228
 
$
0.94
 
$
61,792,184
 
Schedule Of Share Based Compensation Expense [Table Text Block]
The following table summarizes stock-based compensation expense information about stock options and restricted stock for the years ended December 31, 2014 and 2013:
 
 
 
2014
 
2013
 
 
 
 
 
 
 
 
 
Stock-based compensation expense associated with restricted stock
 
$
20,726,512
 
$
5,146,743
 
Stock-based compensation expense associated with stock options
 
 
378,780
 
 
56,405
 
 
 
$
21,105,292
 
$
5,203,148