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Condensed Consoliated Statements of Cash Flows (USD $)
9 Months Ended123 Months Ended
Sep. 30, 2011
Sep. 30, 2010
Sep. 30, 2011
Cash flows from operating activities:   
Net income/(loss)$ 298,105$ 258,414$ (59,832,040)
Adjustments to reconcile net income/(loss) to net cash used in operating activities:   
Equity in losses of Hedrin JV00750,000
Non cash gain on Nordic settlement(4,017,488)0(4,017,488)
Share-based compensation19,210211,7714,419,000
Amortization of OID, issue costs and beneficial conversion feature1,041,745288,7721,978,376
Change in fair value of derivative liability(39,587)(2,696,900)2,455,261
Loss on early extinguishment of debt1,225,912159,0701,384,982
Shares issued in connection with in-licensing agreement00232,500
Shares issued in connection with Ariston milestone220,7010220,701
Warrants issued to consultant00(83,670)
Amortization of intangible assets00145,162
Gain on sale of marketable equity securities00(76,032)
Depreciation1,4042,644232,267
Noncash portion of in-process research and development charge0011,721,623
Loss on impairment and disposition of intangible assets002,462,108
Other0023,917
Changes in operating assets and liabilities, net of acquisitions:   
Decrease in grant receivable244,47900
Decrease in prepaid expenses and other current assets40,50860,61277,999
Decrease/(increase) in other assets10,8590(25,511)
Decrease in accounts payable and accrued expenses(55,797)(332,972)(178,104)
Increase in interest payable843,561620,2191,722,574
Net cash used in operating activities(166,388)(1,428,370)(41,805,865)
Cash flows from investing activities:   
Purchase of property and equipment0(2,844)(242,452)
Cash acquired in connection with acquisitions0519,365493,334
Net cash provided from the purchase and sale of short-term investments00435,938
Proceeds from sale of license00200,001
Net cash provided by investing activities0516,521886,821
Cash flows from financing activities:   
Proceeds related to sale of common stock, net02,163,48628,059,748
Proceeds from sale of preferred stock, net009,046,176
Proceeds from the Hedrin JV agreement003,199,176
Proceeds from sale of notes payable001,509,915
Sale of warrant00150,000
Net repayments of notes payable(100,000)(193,667)(1,207,124)
Other, net00373,433
Net cash provided by/(used in) financing activities(100,000)1,969,81941,131,324
Net increase (decrease) in cash and cash equivalents(266,388)1,057,970212,280
Cash and cash equivalents at beginning of period478,66817,9960
Cash and cash equivalents at end of period$ 212,280$ 1,075,966$ 212,280