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Condensed Consolidated Statements of Stockholders' Equity (Deficiency) (USD $)
Common Stock [Member]
Additional Paid In Capital [Member]
Deficit Accumulated During Development Stage [Member]
Other [Member]
Total
Balance at Dec. 31, 2000$ 0$ 0$ 0$ 0$ 0
Balance (in shares) at Dec. 31, 20000    
Common stock issued during the period, net of expenses2033,7970(4,000)0
Common stock issued during the period, net of expenses (in shares)203,355    
Net loss00(56,796)0(56,796)
Balance at Dec. 31, 20012033,797(56,796)(4,000)(56,796)
Balance (in shares) at Dec. 31, 2001203,355    
Proceeds from subscription receivable0004,0004,000
Stock issued at $0.02 per share for license rights51949001,000
Stock issued at $0.02 per share for license rights (in shares)50,839    
Stock options issued for consulting services060,5890(60,589)0
Amortization of unearned consulting services00022,72122,721
Common stock issued during the period, net of expenses611,704,257001,704,318
Common stock issued during the period, net of expenses (in shares)60,866    
Net loss00(1,037,320)0(1,037,320)
Balance at Dec. 31, 20023151,769,592(1,094,116)(37,868)637,923
Balance (in shares) at Dec. 31, 2002315,060    
Stock issued in connection with acquisition1262,336,115002,336,241
Stock issued in connection with acquisition (in shares)125,752    
Unrealized gain (loss) on short-term investments000(7,760)(7,760)
Payment for fractional shares for stock combination0(300)00(300)
Preferred stock dividends (including imputed amounts)0418,182(418,182)00
Amortization of unearned consulting services00037,86837,868
Preferred stock issued during the period, net of expenses09,045,17601,0009,046,176
Common stock issued during the period, net of expenses26743,66500743,691
Common stock issued during the period, net of expenses (in shares)26,436    
Net loss00(5,960,907)0(5,960,907)
Balance at Dec. 31, 200346714,312,430(7,473,205)(6,760)6,832,932
Balance (in shares) at Dec. 31, 2003467,248    
Unrealized gain (loss) on short-term investments00020,99720,997
Preferred stock dividend accrued00(585,799)0(585,799)
Preferred stock dividends paid by issuance of shares0281,073025281,098
Conversion of preferred stock to common stock311400(171)0
Conversion of preferred stock to common stock (in shares)31,005    
Warrants issued for consulting services0125,5580(120,968)4,590
Amortization of unearned consulting services000100,800100,800
Exercise of stock options130,0990030,100
Exercise of stock options (in shares)552    
Common stock issued during the period, net of expenses673,361,651003,361,718
Common stock issued during the period, net of expenses (in shares)67,379    
Net loss00(5,896,031)0(5,896,031)
Balance at Dec. 31, 200456618,110,951(13,955,035)(6,077)4,150,405
Balance (in shares) at Dec. 31, 2004566,184    
Stock issued in connection with acquisition21511,052,7690011,052,984
Stock issued in connection with acquisition (in shares)214,621    
Unrealized gain (loss) on short-term investments000(12,250)(12,250)
Exercise of warrants668,4850068,491
Exercise of warrants (in shares)5,597    
Preferred stock dividend accrued00(175,663)0(175,663)
Preferred stock dividends paid by issuance of shares0477,736042477,778
Conversion of preferred stock to common stock1637330(896)0
Conversion of preferred stock to common stock (in shares)162,937    
Common stock issued in satisfaction of accounts payable13749,98700750,000
Common stock issued in satisfaction of accounts payable (in shares)13,513    
Exercise of stock options132,3990032,400
Exercise of stock options (in shares)648    
Common stock issued during the period, net of expenses23812,249,9710012,250,209
Common stock issued during the period, net of expenses (in shares)238,354    
Share-based compensation066,971020,16887,139
Net loss00(19,140,997)0(19,140,997)
Balance at Dec. 31, 20051,20242,810,002(33,271,695)9879,540,496
Balance (in shares) at Dec. 31, 20051,201,854    
Unrealized gain (loss) on short-term investments000(987)(987)
Costs associated with private placement0(15,257)00(15,257)
Cashless exercise of warrants00000
Cashless exercise of warrants (in shares)547    
Share-based compensation01,675,499001,675,499
Net loss00(9,695,123)0(9,695,123)
Balance at Dec. 31, 20061,20244,470,244(42,966,818)01,504,628
Balance (in shares) at Dec. 31, 20061,202,401    
Exercise of warrants07,233007,233
Exercise of warrants (in shares)206    
Warrants issued for consulting services083,6700083,670
Common stock issued in satisfaction of accounts payable119,9990020,000
Common stock issued in satisfaction of accounts payable (in shares)556    
Common stock issued with in-licensing agreement at $45.00 per share2112,49800112,500
Common stock issued with in-licensing agreement at $45.00 per share (in shares)2,500    
Common stock issued with in-licensing agreement at $40.00per share3119,99700120,000
Common stock issued with in-licensing agreement at $40.00per share (in shares)3,000    
Cashless exercise of warrants0(6)00(6)
Cashless exercise of warrants (in shares)112    
Common stock issued during the period, net of expenses2047,851,981007,852,185
Common stock issued during the period, net of expenses (in shares)203,710    
Share-based compensation01,440,956001,440,956
Net loss00(12,032,252)0(12,032,252)
Balance at Dec. 31, 20071,41254,106,572(54,999,070)0(891,086)
Balance (in shares) at Dec. 31, 20071,412,485    
Sale of warrant0150,00000150,000
Warrants issued with secured 12% notes0170,12800170,128
Share-based compensation0463,89000463,890
Net loss00(4,268,858)0(4,268,858)
Balance at Dec. 31, 20081,41254,890,590(59,267,928)0(4,375,926)
Balance (in shares) at Dec. 31, 20081,412,485    
Cumulative effect of a change in accounting principle0(150,000)127,7780(22,222)
Balance at January 1, 2009, as adjusted1,41254,740,590(59,140,150)0(4,398,148)
Balance at January 1, 2009, as adjusted (in shares)1,412,485    
Warrants issued with secured 12% notes053,0440053,044
Share-based compensation0353,43800353,438
Net loss00(2,793,285)0(2,793,285)
Balance at Dec. 31, 20091,41255,147,072(61,933,435)0(6,784,951)
Balance (in shares) at Dec. 31, 20091,412,485    
Common stock issued during the period, net of expenses8662,584,621002,585,487
Common stock issued during the period, net of expenses (in shares)865,572    
Shares issued and issuable in Merger1411,475,906015,8901,491,937
Shares issued and issuable in Merger (in shares)141,248    
Derivative liability associated with issuance of common stock at $0.070(3,497,898)00(3,497,898)
Share-based compensation0217,47900217,479
Net loss00623,6450623,645
Balance at Dec. 31, 20102,41955,927,180(61,309,790)15,890(5,364,301)
Balance (in shares) at Dec. 31, 20102,419,305    
Shares issued and issuable in Merger177220,52400220,701
Shares issued and issuable in Merger (in shares)176,561    
Derivative liability associated with issuance of common stock at $0.070(115,000)00(115,000)
Share-based compensation019,2100019,210
Beneficial conversion feature of Secured 12% Notes Payable and interest02,245,596002,245,596
Roundup adjustment for 1 for 50 reverse stock split (in shares)251    
Conversion of Secured 12% Notes Payable and interest into common stock4,8022,396,269  2,401,071
Conversion of Secured 12% Notes Payable and interest into common stock (in shares)4,802,199    
Net loss00298,1050298,105
Balance at Sep. 30, 2011$ 7,398$ 60,693,779$ (61,011,685)$ 15,890$ (294,618)
Balance (in shares) at Sep. 30, 20117,398,316