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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 G1BxUGpQV1AAry0etpc4xZohQjS9YEPf/wq5Un2swCK4QRbDA8YwdlNFNHnMaDh8
 TVGeHMT41iBh3qPSC6FxWw==

<SEC-DOCUMENT>9999999995-09-001692.txt : 20090619
<SEC-HEADER>9999999995-09-001692.hdr.sgml : 20090619
<ACCEPTANCE-DATETIME>20090619001510
ACCESSION NUMBER:		9999999995-09-001692
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20090618
DATE AS OF CHANGE:		20090619
EFFECTIVENESS DATE:		20090618

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SANGAMO BIOSCIENCES INC
		CENTRAL INDEX KEY:			0001001233
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				680359556
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-134516
		FILM NUMBER:		09899776

	BUSINESS ADDRESS:	
		STREET 1:		501 CANAL BLVD
		STREET 2:		SUITE A100
		CITY:			RICHMOND
		STATE:			CA
		ZIP:			94804
		BUSINESS PHONE:		5109706000

	MAIL ADDRESS:	
		STREET 1:		501 CANAL BLVD
		STREET 2:		SUITE A100
		CITY:			RICHMOND
		STATE:			CA
		ZIP:			94804
</SEC-HEADER>
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<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2009-06-18</finalEffectivenessDispDate>
        <accessionNumber>0001193125-09-132486</accessionNumber>
        <submissionType>POS AM</submissionType>
        <filer>
            <cik>0001001233</cik>
            <entityName>SANGAMO BIOSCIENCES INC</entityName>
            <fileNumber>333-134516</fileNumber>
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