CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive (Loss) Income	Non- Controlling Interest
Beginning balance (in shares) at Dec. 31, 2020		142,063,203
Beginning balance at Dec. 31, 2020	$ 497,366	$ 1,421	$ 1,269,375	$ (777,981)	$ 5,419	$ (868)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		2,007,932
Issuance of common stock in connection with at-the-market offering, net of offering expenses	27,099	$ 20	27,079
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		1,200,871
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	1,594	$ 12	1,582
Issuance of common stock under employee stock purchase plan (in shares)		244,570
Issuance of common stock under employee stock purchase plan	2,054	$ 2	2,052
Stock-based compensation	24,880		24,880
Acquisition of additional shares of Sangamo France	(134)		(70)			(64)
Foreign currency translation adjustment	(6,006)				(6,006)
Net pension gains	0
Unrealized gain (loss) on marketable securities, net of tax	(36)				(36)
Buy-out of non-controlling interest	(943)		(943)			943
Net loss	(140,801)			(140,790)		(11)
Ending balance (in shares) at Sep. 30, 2021		145,516,576
Ending balance at Sep. 30, 2021	406,016	$ 1,455	1,323,955	(918,771)	(623)	0
Beginning balance (in shares) at Jun. 30, 2021		145,106,901
Beginning balance at Jun. 30, 2021	445,457	$ 1,451	1,313,102	(871,083)	1,987	0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		202,705
Issuance of common stock in connection with at-the-market offering, net of offering expenses	2,367	$ 2	2,365
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		206,970
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	617	$ 2	615
Stock-based compensation	7,873		7,873
Foreign currency translation adjustment	(2,565)				(2,565)
Net pension gains	0
Unrealized gain (loss) on marketable securities, net of tax	(45)				(45)
Net loss	(47,688)			(47,688)		0
Ending balance (in shares) at Sep. 30, 2021		145,516,576
Ending balance at Sep. 30, 2021	406,016	$ 1,455	1,323,955	(918,771)	(623)	$ 0
Beginning balance (in shares) at Dec. 31, 2021		145,921,530
Beginning balance at Dec. 31, 2021	375,343	$ 1,459	1,334,138	(956,267)	(3,987)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		14,711,770
Issuance of common stock in connection with at-the-market offering, net of offering expenses	66,448	$ 147	66,301
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		925,455
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	(1,838)	$ 9	(1,847)
Issuance of common stock under employee stock purchase plan (in shares)		359,468
Issuance of common stock under employee stock purchase plan	1,115	$ 4	1,111
Stock-based compensation	23,402		23,402
Foreign currency translation adjustment	(14,040)				(14,040)
Net pension gains	130				130
Unrealized gain (loss) on marketable securities, net of tax	(1,101)				(1,101)
Buy-out of non-controlling interest	0
Net loss	(140,305)			(140,305)
Ending balance (in shares) at Sep. 30, 2022		161,918,223
Ending balance at Sep. 30, 2022	309,154	$ 1,619	1,423,105	(1,096,572)	(18,998)
Beginning balance (in shares) at Jun. 30, 2022		153,352,502
Beginning balance at Jun. 30, 2022	318,281	$ 1,534	1,373,324	(1,043,417)	(13,160)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		8,483,104
Issuance of common stock in connection with at-the-market offering, net of offering expenses	42,174	$ 85	42,089
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		82,617
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	(101)		(101)
Stock-based compensation	7,793		7,793
Foreign currency translation adjustment	(6,028)				(6,028)
Net pension gains	55				55
Unrealized gain (loss) on marketable securities, net of tax	135				135
Net loss	(53,155)			(53,155)
Ending balance (in shares) at Sep. 30, 2022		161,918,223
Ending balance at Sep. 30, 2022	$ 309,154	$ 1,619	$ 1,423,105	$ (1,096,572)	$ (18,998)