CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive (Loss) Income	Non- Controlling Interest
Beginning balance (in shares) at Dec. 31, 2020		142,063,203
Beginning balance at Dec. 31, 2020	$ 497,366	$ 1,421	$ 1,269,375	$ (777,981)	$ 5,419	$ (868)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		1,805,227
Issuance of common stock in connection with at-the-market offering, net of offering expenses	24,732	$ 18	24,714
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		993,901
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	977	$ 10	967
Issuance of common stock under employee stock purchase plan (in shares)		244,570
Issuance of common stock under employee stock purchase plan	2,054	$ 2	2,052
Stock-based compensation	17,007		17,007
Acquisition of additional shares of Sangamo France	(134)		(70)			(64)
Foreign currency translation adjustment	(3,441)				(3,441)
Net pension gains	0
Net unrealized loss on marketable securities, net of tax	9				9
Buy-out of non-controlling interest	(943)		(943)			943
Net loss	(93,113)			(93,102)		(11)
Ending balance (in shares) at Jun. 30, 2021		145,106,901
Ending balance at Jun. 30, 2021	445,457	$ 1,451	1,313,102	(871,083)	1,987	0
Beginning balance (in shares) at Mar. 31, 2021		143,713,765
Beginning balance at Mar. 31, 2021	469,417	$ 1,437	1,292,118	(823,914)	714	(938)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		770,465
Issuance of common stock in connection with at-the-market offering, net of offering expenses	9,081	$ 8	9,073
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		378,101
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	1,393	$ 4	1,389
Issuance of common stock under employee stock purchase plan (in shares)		244,570
Issuance of common stock under employee stock purchase plan	2,054	$ 2	2,052
Stock-based compensation	9,483		9,483
Acquisition of additional shares of Sangamo France	(70)		(70)
Foreign currency translation adjustment	1,308				1,308
Net pension gains	0
Net unrealized loss on marketable securities, net of tax	(35)				(35)
Buy-out of non-controlling interest			(943)			943
Net loss	(47,174)			(47,169)		(5)
Ending balance (in shares) at Jun. 30, 2021		145,106,901
Ending balance at Jun. 30, 2021	445,457	$ 1,451	1,313,102	(871,083)	1,987	$ 0
Beginning balance (in shares) at Dec. 31, 2021		145,921,530
Beginning balance at Dec. 31, 2021	375,343	$ 1,459	1,334,138	(956,267)	(3,987)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		6,228,666
Issuance of common stock in connection with at-the-market offering, net of offering expenses	24,274	$ 62	24,212
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		842,838
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	(1,737)	$ 9	(1,746)
Issuance of common stock under employee stock purchase plan (in shares)		359,468
Issuance of common stock under employee stock purchase plan	1,115	$ 4	1,111
Stock-based compensation	15,609		15,609
Foreign currency translation adjustment	(8,012)				(8,012)
Net pension gains	75				75
Net unrealized loss on marketable securities, net of tax	(1,236)				(1,236)
Buy-out of non-controlling interest	0
Net loss	(87,150)			(87,150)
Ending balance (in shares) at Jun. 30, 2022		153,352,502
Ending balance at Jun. 30, 2022	318,281	$ 1,534	1,373,324	(1,043,417)	(13,160)
Beginning balance (in shares) at Mar. 31, 2022		146,664,760
Beginning balance at Mar. 31, 2022	334,522	$ 1,467	1,340,254	(1,000,244)	(6,955)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with at-the-market offering, net of offering expenses (in shares)		6,228,666
Issuance of common stock in connection with at-the-market offering, net of offering expenses	24,274	$ 62	24,212
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax (in shares)		99,608
Issuance of common stock upon exercise of stock options and in connection with restricted stock units, net of tax	(170)	$ 1	(171)
Issuance of common stock under employee stock purchase plan (in shares)		359,468
Issuance of common stock under employee stock purchase plan	1,115	$ 4	1,111
Stock-based compensation	7,918		7,918
Foreign currency translation adjustment	(6,108)				(6,108)
Net pension gains	56				56
Net unrealized loss on marketable securities, net of tax	(153)				(153)
Net loss	(43,173)			(43,173)
Ending balance (in shares) at Jun. 30, 2022		153,352,502
Ending balance at Jun. 30, 2022	$ 318,281	$ 1,534	$ 1,373,324	$ (1,043,417)	$ (13,160)