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MAJOR CUSTOMERS, PARTNERSHIPS AND STRATEGIC ALLIANCES - Additional Information (Detail)
1 Months Ended 3 Months Ended 16 Months Ended 34 Months Ended
Apr. 05, 2018
USD ($)
Apr. 30, 2020
USD ($)
$ / shares
shares
Apr. 30, 2020
USD ($)
$ / shares
Mar. 31, 2020
USD ($)
$ / shares
Feb. 29, 2020
USD ($)
product_target
Dec. 31, 2019
USD ($)
Sep. 30, 2019
USD ($)
May 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
milestone
May 31, 2017
USD ($)
Jan. 31, 2014
USD ($)
program
Mar. 31, 2020
USD ($)
option
milestone
product
Mar. 31, 2019
USD ($)
Sep. 30, 2019
USD ($)
Mar. 31, 2020
USD ($)
Feb. 28, 2020
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenue reduction due to decrease in measure of proportional cumulative performance, percentage                         38.00%      
Revenues                       $ 13,076,000 $ 8,071,000      
Other long-term liabilities       $ 5,880,000   $ 5,711,000           5,880,000     $ 5,880,000  
California Institute For Regenerative Medicine Agreement                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Funds due under the agreement               $ 8,000,000.0                
Other long-term liabilities       5,900,000   5,700,000           5,900,000     5,900,000  
California Institute For Regenerative Medicine Agreement | Research Grants                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues                           $ 5,200,000    
Biogen MA, Inc. | Collaboration and License Agreement                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Proceeds from collaborators         $ 125,000,000.0                      
Maximum milestone payment receivable         $ 2,370,000,000                      
Number of product targets | product_target         12                      
Number of product targets selected | product_target         3                      
Number of additional product targets | product_target         9                      
Target selection period         5 years                      
Biogen MA, Inc. | Collaboration and License Agreement | Subsequent Event                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Proceeds from collaborators     $ 125,000,000.0                          
Biogen MA, Inc. | Collaboration and License Agreement | Pre-approval Milestone                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Maximum milestone payment receivable         $ 925,000,000.0                      
Biogen MA, Inc. | Collaboration and License Agreement | Sales-based Milestone                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Maximum milestone payment receivable         $ 1,450,000,000                      
Biogen MA, Inc. | Stock Purchase Agreement                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Standstill restriction period         3 years                      
Standstill restriction, ownership threshold percentage ownership percentage                               5.00%
Agreement restriction, percentage of shares held                               50.00%
Voting provisions expiration period         2 years                      
Voting provisions, ownership threshold percentage                               5.00%
Biogen MA, Inc. | Stock Purchase Agreement | Subsequent Event                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Number of shares issued in transaction (in shares) | shares   24,420,157                            
Sale of stock, price per share (in dollars per share) | $ / shares   $ 9.2137 $ 9.2137                          
Consideration received on transaction   $ 225,000,000.0 $ 225,000,000.0                          
Kite Pharma Inc                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues                       7,219,000 8,312,000      
Kite Pharma Inc | Collaboration Agreements                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues                       $ 6,227,000 6,159,000      
Kite Pharma Inc | Collaboration and License Agreement                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Milestone payments received $ 150,000,000.0                              
Initial research term of agreement 6 years                              
Number of options to extend initial research term | option                       2        
Extended research term of agreement                       1 year        
Separate upfront fee $ 10,000,000.0                              
Collaborative arrangement estimated reimbursable service costs for new research plan             $ 3,400,000                  
Collaborative arrangement transaction price 189,300,000                              
Revenues under agreement 150,000,000.0                              
Collaborative arrangement estimated reimbursable service costs 39,300,000                              
Deferred revenue       100,300,000   106,500,000           $ 100,300,000     100,300,000  
Kite Pharma Inc | Collaboration and License Agreement | Maximum                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received 3,010,000,000.00                              
Kite Pharma Inc | Collaboration and License Agreement | Achievement of Specified Research, Clinical Development, Regulatory and First Commercial Sale Milestones                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Contingent development - and sales-based milestone payments to be received 1,260,000,000                              
Kite Pharma Inc | Collaboration and License Agreement | Achievement of Specified Sales-based Milestones if Annual Worldwide Net Sales of Licensed Products Reach Specified Levels                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Contingent development - and sales-based milestone payments to be received $ 1,750,000,000                              
Pfizer                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Milestone payments received                 $ 12,000,000.0              
Collaborative arrangement transaction price                 $ 12,000,000.0              
Revenues under agreement           25,000,000.0       $ 70,000,000.0   1,000,000.0     25,000,000.0  
Deferred revenue       1,000,000.0   4,000,000.0           1,000,000.0     1,000,000.0  
Contract to perform for others, cumulative compensation earned       24,700,000               24,700,000     24,700,000  
Revenue reduction due to decrease in measure of proportional cumulative performance                         3,000,000.0      
Increase (decrease) in revenue       2,400,000                        
Increase (decrease) in net loss       $ 2,400,000                        
Increase (decrease) in basic net loss per share (in dollars per share) | $ / shares       $ 0.02                        
Pfizer | Collaboration Agreements                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues                       360,000 615,000      
Pfizer | C9ORF72                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Deferred revenue       $ 7,600,000   8,000,000.0           7,600,000     7,600,000  
Number of milestones included in transaction price | milestone                 0              
Pfizer | Maximum | SB-525                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Potential amount to be funded for achievement of specified commercialized and sales milestones                   266,500,000            
Milestone revenue receivable                   300,000,000.0            
Pfizer | Maximum | Other Products                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Milestone revenue receivable                   175,000,000.0            
Pfizer | Achievement of Specified Clinical Development Intellectual Property and Regulatory Milestones | Maximum                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                   208,500,000            
Pfizer | Achievement of First Commercial Sale Milestones | Maximum                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                   $ 475,000,000.0            
Pfizer | Achievement of Specified Preclinical Development Clinical Development and First Commercial Sale Milestones | Maximum | C9ORF72                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                 $ 60,000,000.0              
Pfizer | Achievement of Commercial Milestones | Maximum | C9ORF72                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                 $ 90,000,000.0              
Pfizer SB-525                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Collaborative arrangement transaction price                       $ 104,000,000.0        
Number of products approved | product                       0        
Research Service Fees                       $ 79,000,000.0        
Agreement termination, term                       15 years        
Revenues                       $ 3,183,000 (3,040,000)      
Pfizer SB-525 | Collaboration Agreements                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues                       $ 2,190,000 (3,040,000)      
Pfizer SB-525 | SB-525                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Number of milestones included in transaction price | milestone                       0        
Pfizer SB-525 | Amended Collaboration And License Agreement                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Deferred revenue       300,000               $ 300,000     300,000  
Milestone revenue receivable       25,000,000.0               $ 25,000,000.0     25,000,000.0  
Sanofi                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues under agreement                     $ 20,000,000.0          
Number of products approved | product                       0        
Agreement termination, term                       180 days        
Increase (decrease) in revenue       (2,200,000)                        
Increase (decrease) in net loss       $ (2,200,000)                        
Increase (decrease) in basic net loss per share (in dollars per share) | $ / shares       $ (0.02)                        
Revenues                       $ 499,000 1,949,000      
Number of research programs | program                     2          
Sanofi | Collaboration Agreements                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Revenues                       (729,000) $ 752,000      
Sanofi | Collaboration and License Agreement                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Collaborative arrangement transaction price                     $ 93,300,000          
Revenues under agreement                     20,000,000.0          
Collaborative arrangement estimated reimbursable service costs                     59,800,000          
Deferred revenue       $ 2,900,000   1,700,000           $ 2,900,000     2,900,000  
Number of milestones included in transaction price | milestone                       0        
Cumulative milestone achieved       6,800,000               $ 6,800,000     6,800,000  
Sanofi | Collaboration and License Agreement | Maximum                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                     276,300,000          
Sanofi | Collaboration and License Agreement | Milestone Two                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Milestone revenue receivable           $ 7,500,000                    
Milestone revenue reversal       300,000               300,000     300,000  
Sanofi | Collaboration and License Agreement | Milestone Three                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Milestone revenue receivable       13,500,000               13,500,000     13,500,000  
Sanofi | Collaboration and License Agreement | ST-40 Beta Thalassemia Phase 1 Clinical Trial Milestone                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Milestone payments received                       6,000,000.0        
Cumulative milestone achieved       5,500,000               5,500,000     5,500,000  
Milestone revenue reversal       $ 200,000               $ 200,000     $ 200,000  
Sanofi | Collaboration and License Agreement | Achievement Of Specified Clinical Development And Regulatory Milestones | Maximum                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                     115,800,000          
Sanofi | Collaboration and License Agreement | Achievement of Specified Sales Milestones | Maximum                                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                
Development and sales-based milestone payments to be received                     $ 160,500,000