Other Balance Sheet Details (Tables)

12 Months Ended

Dec. 31, 2019

Balance Sheet Related Disclosures [Abstract]

Summary of Property and Equipment, Net

Property and equipment, net consist of the following (in thousands):

	December 31,
	2019		2018
Laboratory equipment	$	17,179	$	11,466
Furniture and fixtures	4,639		3,840
Leasehold improvements	13,888		3,640
Buildings	—		3,876
Construction in progress	5,901		65,211
	41,607		88,033
Less: accumulated depreciation and amortization	(11,681)		(9,310)
Property and equipment, net	$	29,926	$	78,723

Schedule of Intangible Assets and Goodwill

The changes in intangible assets were as follows (in thousands):

	December 31,
	2019		2018
Balance, beginning of year	$	54,243	$	—
Indefinite-lived assets - IPR&D	—		55,019
Foreign currency translation adjustment	(1,087)		(776)
Balance, end of year	$	53,156	$	54,243

The changes in goodwill were as follows (in thousands):

	December 31,
	2019		2018
Balance, beginning of year	$	40,044	$	1,585
Goodwill acquired	—		38,995
Foreign currency translation adjustment	(771)		(536)
Balance, end of year	$	39,273	$	40,044

Summary of Accounts Payable and Accrued Liabilities

Accounts payable and accrued liabilities consist of the following (in thousands):

	December 31,
	2019		2018
Accounts payable	$	6,671	$	3,355
Accrued research and development expenses	4,102		10,999
Operating lease liabilities - current	3,214		—
Accrued professional fees	1,118		1,930
Deferred rent	—		204
Other	2,451		4,969
Total accounts payable and accrued liabilities	$	17,556	$	21,457