Major Customers, Partnerships and Strategic Alliances (Tables)

3 Months Ended

Mar. 31, 2018

Bioverativ Inc [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement for the three months ended March 31, 2018 and 2017 were as follows (in thousands):

	Three Months Ended
	March 31,
	2018		2017
Revenue related to Bioverativ agreement:
Recognition of upfront fee	$	1,154	$	442
Research services		3,228		1,709
Total	$	4,382	$	2,151

Shire AG [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement for the three months ended March 31, 2018 and 2017 were as follows (in thousands):

	Three Months Ended
	March 31,
	2018		2017
Revenue related to Shire agreement:
Recognition of upfront fee	$	—	$	583
Research services		—		107
Total	$	—	$	690