Property and Equipment - Summary of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 12,196	$ 7,762
Less accumulated depreciation and amortization	(5,639)	(4,846)
Property and equipment, Net	6,557	2,916
Laboratory equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	6,206	5,801
Furniture and fixtures [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	636	652
Leasehold improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	1,330	$ 1,309
Buildings [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	3,876
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 148