Major Customers, Partnerships and Strategic Alliances (Tables)

6 Months Ended

Jun. 30, 2016

Revenues recognized under the agreement with Biogen for the three and six months ended June 30, 2016 and 2015 were as follows (in thousands):

	Three months ended				Six months ended
	June 30,				June 30,
	2016		2015		2016		2015
Revenue related to Biogen Collaboration:
Recognition of upfront fee	$	608	$	1,540	$	1,216	$	3,063
Research services		1,894		1,701		3,925		3,233
Total	$	2,502	$	3,241	$	5,141	$	6,296

Revenues recognized under the agreement with Shire for the three and six months ended June 30, 2016 and 2015 were as follows (in thousands):

	Three months ended				Six months ended
	June 30,				June 30,
	2016		2015		2016		2015
Revenue related to Shire Collaboration:
Recognition of upfront fee	$	541	$	542	$	1,083	$	1,083
Research services		363		3,894		792		8,416
Total	$	904	$	4,436	$	1,875	$	9,499

Revenues recognized under the agreement with Sigma for the three and six months ended June 30, 2016 and 2015 were as follows (in thousands):

	Three months ended				Six months ended
	June 30,				June 30,
	2016		2015		2016		2015
Revenue related to Sigma Collaboration:
Royalty revenues	$	49	$	28	$	61	$	293
License fee revenues		63		21		70		4,277
Total	$	112	$	49	$	131	$	4,570