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Major Customers, Partnerships and Strategic Alliances - Revenues Recognized under Agreement (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 12 Months Ended
Sep. 30, 2014
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Biogen [Member]        
Revenue related to Biogen Collaboration:        
Recognition of upfront fee   $ 5,313us-gaap_LicenseAndServicesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_BiogenMember
   
Research services   7,751sgmo_ResearchServiceRevenueUnderCollaborationAgreement
/ us-gaap_CounterpartyNameAxis
= sgmo_BiogenMember
   
Total   13,064us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_BiogenMember
   
Shire AG [Member]        
Revenue related to Biogen Collaboration:        
Recognition of milestone 1,000us-gaap_RevenueRecognitionMilestoneMethodRevenueRecognized
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
1,000us-gaap_RevenueRecognitionMilestoneMethodRevenueRecognized
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
   
Royalty revenues   0us-gaap_RoyaltyRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
   
Research services   22,765sgmo_ResearchServiceRevenueUnderCollaborationAgreement
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
14,286sgmo_ResearchServiceRevenueUnderCollaborationAgreement
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
9,026sgmo_ResearchServiceRevenueUnderCollaborationAgreement
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
Total   25,932us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
16,453us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
11,012us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
Shire AG [Member] | Upfront Fee And Milestone Revenue        
Revenue related to Biogen Collaboration:        
Recognition of upfront fee   2,167us-gaap_LicenseAndServicesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
/ us-gaap_DeferredRevenueArrangementTypeAxis
= sgmo_UpfrontFeeAndMilestoneRevenueMember
2,167us-gaap_LicenseAndServicesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
/ us-gaap_DeferredRevenueArrangementTypeAxis
= sgmo_UpfrontFeeAndMilestoneRevenueMember
1,986us-gaap_LicenseAndServicesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_ShireAgMember
/ us-gaap_DeferredRevenueArrangementTypeAxis
= sgmo_UpfrontFeeAndMilestoneRevenueMember
Sigma-Aldrich Corporation [Member]        
Revenue related to Biogen Collaboration:        
Royalty revenues   344us-gaap_RoyaltyRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
824us-gaap_RoyaltyRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
1,288us-gaap_RoyaltyRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
License fee and milestone revenues   448us-gaap_LicensesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
1,351us-gaap_LicensesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
1,000us-gaap_LicensesRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
Total   $ 792us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
$ 2,175us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember
$ 2,288us-gaap_ContractsRevenue
/ us-gaap_CounterpartyNameAxis
= sgmo_SigmaAldrichCorporationMember