Major Customers, Partnerships and Strategic Alliances (Tables)

12 Months Ended

Dec. 31, 2013

Shire AG [Member]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Shire for the years ended December 31, 2013 and 2012, were as follows (in thousands):

	Year ended December 31,
	2013		2012
Revenues related to Shire Collaboration:
Amortization of upfront fee	$	2,167	$	1,986
Research services		14,286		9,026
Total	$	16,453	$	11,012

Sigma-Aldrich Corporation [Member]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Sigma for the years ended December 31, 2013, 2012 and 2011, were as follows (in thousands):

	Year ended December 31,
	2013		2012		2011
Revenue related to Sigma Collaboration:
Royalty revenues	$	824	$	1,288	$	938
License fee and milestone revenues		1,351		1,000		671
Total	$	2,175	$	2,288	$	1,609