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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands, unless otherwise specified
6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Operating Activities:    
Net loss $ (12,996) $ (19,837)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 334 319
Amortization of premium/discount on marketable securities 490 786
Stock-based compensation 2,607 3,929
Changes in operating assets and liabilities:    
Interest receivable 132 (172)
Accounts receivable (2,322) (1,015)
Prepaid expenses and other assets (268) (356)
Accounts payable and accrued liabilities (2,867) (3,005)
Accrued compensation and employee benefits (378) (355)
Deferred revenues 12,122 277
Net cash used in operating activities (3,146) (19,429)
Investing Activities:    
Purchases of investments (47,505) (78,884)
Maturities of investments 52,120 44,556
Purchases of property and equipment (263) (196)
Net cash provided by (used in) investing activities 4,352 (34,524)
Financing Activities:    
Proceeds from issuance of common stock 504 51,590
Net cash provided by financing activities 504 51,590
Net increase/ (decrease) in cash and cash equivalents 1,710 (2,363)
Cash and cash equivalents, beginning of period 16,766 10,784
Cash and cash equivalents, end of period $ 18,476 $ 8,421