Other Financial Information (Tables)

12 Months Ended

Dec. 31, 2018

Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of the following at December 31 (in thousands):

	2018		2017
Laboratory supplies	$	11,974	$	13,085
Other prepaid expenses and other current assets		4,321		4,689
Prepaid expenses and other current assets	$	16,295	$	17,774

Property and Equipment, Net

Property and equipment is comprised of the following at December 31 (in thousands):

	2018			2017
Machinery and equipment	$	35,723		$	35,409
Leasehold improvements		22,276			23,664
Computer hardware		4,763			5,091
Construction in progress		1,347			1,129
		64,109			65,293
Less ― accumulated depreciation		(35,683	)		(29,306	)
Property and equipment, net	$	28,426		$	35,987

Accrued Expenses

Accrued expenses consist of the following at December 31 (in thousands):

	2018		2017
Employee benefits and compensation	$	9,632	$	11,186
Research and development accruals		8,476		17,542
Other accrued expenses		1,442		882
Accrued expenses	$	19,550	$	29,610