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Goodwill and Other Intangible Assets (Tables)
12 Months Ended
Dec. 31, 2018
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of Goodwill
The changes in the carrying amounts of goodwill for the years ended December 31, 2018 and 2017 were as follows (in thousands):
 
 
 
Year Ended

December 31,
 
 
 
2018
 
 
2017
 
Beginning balance
 
$
53,563
 
 
$
51,673
 
Currency translation adjustments
 
 
(1,596
)
 
 
1,890
 
Ending balance
 
$
51,967
 
 
$
53,563
 
Schedule of Identifiable Intangible Assets
Purchased intangible assets consisted of the following as of December 31, 2018 and 2017 (in thousands):
 
 
 
December 31, 2018
 
 
December 31, 2017
 
 
 
Gross

Carrying

Amount
 
 
Accumulated

Amortization
 
 
Intangible

Assets, Net
 
 
Gross

Carrying

Amount
 
 
Accumulated

Amortization
 
 
Intangible

Assets, Net
 
Finite-lived intangible assets:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Proprietary adjuvant technology
 
$
8,357
 
 
$
(2,263
)
 
$
6,094
 
 
$
9,086
 
 
$
(2,006
)
 
$
7,080
 
Collaboration agreements
 
 
3,773
 
 
 
(3,326
)
 
 
447
 
 
 
4,103
 
 
 
(3,310
)
 
 
793
 
Total identifiable intangible assets
 
$
12,130
 
 
$
(5,589
)
 
$
6,541
 
 
$
13,189
 
 
$
(5,316
)
 
$
7,873
 
Schedule of Estimated Amortization Expense Estimated amortization expense for existing intangible assets for each of the five succeeding years ending December 31, is as follows (in thousands):
 
Year
 
Amount
 
2019
 
$
700
 
2020
 
 
583
 
2021
 
 
418
 
2022
 
 
418
 
2023
 
 
418