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Other Financial Information
12 Months Ended
Dec. 31, 2018
Other Financial Information
Note 8 – Other Financial Information
 
Prepaid Expenses and Other Current Assets
 
Prepaid expenses and other current assets consist of the following at December 31 (in thousands):
 
 
 
2018
 
 
2017
 
Laboratory supplies
 
$
11,974
 
 
$
13,085
 
Other prepaid expenses and other current assets
 
 
4,321
 
 
 
4,689
 
Prepaid expenses and other current assets
 
$
16,295
 
 
$
17,774
 
 
Property and Equipment, net
 
Property and equipment is comprised of the following at December 31 (in thousands):
 
 
 
2018
 
 
2017
 
Machinery and equipment
 
$
35,723
 
 
$
35,409
 
Leasehold improvements
 
 
22,276
 
 
 
23,664
 
Computer hardware
 
 
4,763
 
 
 
5,091
 
Construction in progress
 
 
1,347
 
 
 
1,129
 
 
 
 
64,109
 
 
 
65,293
 
Less ― accumulated depreciation
 
 
(35,683
)
 
 
(29,306
)
Property and equipment, net
 
$
28,426
 
 
$
35,987
 
 
Depreciation expense was approximately $7.4 million, $7.6 million and $7.7 million for the years ended December 31, 2018, 2017 and 2016, respectively.
 
Accrued Expenses
 
Accrued expenses consist of the following at December 31 (in thousands):
 
 
 
2018
 
 
2017
 
Employee benefits and compensation
 
$
9,632
 
 
$
11,186
 
Research and development accruals
 
 
8,476
 
 
 
17,542
 
Other accrued expenses
 
 
1,442
 
 
 
882
 
Accrued expenses
 
$
19,550
 
 
$
29,610