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Other Financial Information
12 Months Ended
Dec. 31, 2017
Other Financial Information [Abstract]  
Other Financial Information
Note 8 – Other Financial Information
 
Prepaid Expenses and Other Current Assets
 
Prepaid expenses and other current assets consist of the following at December 31 (in thousands):
 
 
 
2017
 
2016
 
Laboratory supplies
 
$
13,085
 
$
15,736
 
Other prepaid expenses and other current assets
 
 
4,689
 
 
6,301
 
Prepaid expenses and other current assets
 
$
17,774
 
$
22,037
 
 
Property and Equipment, net
 
Property and equipment is comprised of the following at December 31 (in thousands):
 
 
 
2017
 
2016
 
Machinery and equipment
 
$
35,409
 
$
32,596
 
Leasehold improvements
 
 
23,664
 
 
22,642
 
Computer hardware
 
 
5,091
 
 
4,285
 
Construction in progress
 
 
1,129
 
 
2,938
 
 
 
 
65,293
 
 
62,461
 
Less — accumulated depreciation
 
 
(29,306)
 
 
(22,277)
 
Property and equipment, net
 
$
35,987
 
$
40,184
 
 
Depreciation expense was approximately $7.6 million, $7.7 million and $5.1 million for the years ended December 31, 2017, 2016 and 2015, respectively.
 
Accrued Expenses
 
Accrued expenses consist of the following at December 31 (in thousands):
 
 
 
2017
 
2016
 
Employee benefits and compensation
 
$
11,186
 
$
7,300
 
Research and development accruals
 
 
17,542
 
 
15,744
 
Other accrued expenses
 
 
882
 
 
1,464
 
Accrued expenses
 
$
29,610
 
$
24,508