Other Financial Information (Accrued Expenses) (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Employee benefits and compensation	$ 7,300	$ 11,255
Research and development accruals	15,744	13,814
Other accrued expenses	1,464	1,665
Accrued expenses	$ 24,508	$ 26,734