Other Financial Information (Tables)

12 Months Ended

Dec. 31, 2016

Other Financial Information [Abstract]

Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of the following at December 31 (in thousands):

	2016		2015
Laboratory supplies	$	15,736	$	12,968
Other prepaid expenses and other current assets		6,068		6,349
Prepaid expenses and other current assets	$	21,804	$	19,317

Property and Equipment, Net

Property and equipment is comprised of the following at December 31 (in thousands):

	2016		2015
Machinery and equipment	$	32,596	$	26,461
Leasehold improvements		22,642		12,440
Computer software and hardware		4,285		3,091
Construction in progress		2,938		6,167
		62,461		48,159
Less — accumulated depreciation and amortization		(22,277)		(15,817)
Property and equipment, net	$	40,184	$	32,342

Accrued Expenses

Accrued expenses consist of the following at December 31 (in thousands):

	2016		2015
Employee benefits and compensation	$	7,300	$	11,255
Research and development accruals		15,744		13,814
Other accrued expenses		1,464		1,665
Accrued expenses	$	24,508	$	26,734