CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenue:
Government contracts	$ 102	$ 6,307	$ 2,182	$ 29,273
Research and development collaborations	3,129	218	7,772	1,124
Total revenue	3,231	6,525	9,954	30,397
Expenses:
Research and development	52,983	30,664	186,839	86,740
General and administrative	13,556	9,060	38,183	21,991
Total expenses	66,539	39,724	225,022	108,731
Loss from operations	(63,308)	(33,199)	(215,068)	(78,334)
Other income (expense):
Investment income	554	194	1,701	450
Interest expense	(3,511)	(64)	(9,457)	(126)
Other income (expense)	11	(51)	(33)	(121)
Net loss	$ (66,254)	$ (33,120)	$ (222,857)	$ (78,131)
Basic and diluted net loss per share	$ (0.24)	$ (0.12)	$ (0.82)	$ (0.3)
Basic and diluted weighted average number of common shares outstanding	271,064	269,554	270,669	259,703