Other Financial Information (Tables)

12 Months Ended

Dec. 31, 2015

Other Financial Information [Abstract]

Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of the following at December 31 (in thousands):

	2015		2014
Laboratory supplies	$	12,968	$	7,564
Other prepaid expenses and other current assets		6,349		1,631
Prepaid expenses and other current assets	$	19,317	$	9,195

Property and Equipment, Net

Property and equipment is comprised of the following at December 31 (in thousands):

	2015		2014
Machinery and equipment	$	26,461	$	16,712
Leasehold improvements		12,440		8,843
Computer software and hardware		3,091		1,733
Construction in progress		6,167		3,719
		48,159		31,007
Less — accumulated depreciation and amortization		(15,817)		(11,270)
Property and equipment, net	$	32,342	$	19,737

Accrued Expenses

Accrued expenses consist of the following at December 31 (in thousands):

	2015		2014
Employee benefits and compensation	$	11,255	$	8,597
Research and development accruals		13,814		9,826
Other accrued expenses		1,665		974
Accrued expenses	$	26,734	$	19,397