Note 8 - Other Financial Information

Prepaid Expenses

Prepaid expenses consist of the following at December 31 (in thousands):

	2012		2011
Laboratory supplies	$	1,592	$	1,616
Other prepaid expenses		967		825
Prepaid expenses	$	2,559	$	2,441

Property and Equipment, net

Property and equipment is comprised of the following at December 31 (in thousands):

	2012			2011
Construction in progress	$	5,248		$	56
Machinery and equipment		8,035			7,131
Leasehold improvements		4,629			4,548
Computer software and hardware		698			669
		18,610			12,404
Less ― accumulated depreciation and amortization		(7,154	)		(5,547	)
Property and equipment, net	$	11,456		$	6,857

Depreciation and amortization expense was approximately $1.7 million, $1.6 million and $1.4 million for the years ended December 31, 2012, 2011 and 2010, respectively. Machinery and equipment included $0.4 million of equipment acquired under a capital lease (see Note 9) with accumulated depreciation of less than $0.1 million as of December 31, 2012.

Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities consist of the following at December 31 (in thousands):

	2012		2011
Employee benefits and compensation	$	3,242	$	2,283
Research and development accruals		3,396		1,213
Other accrued expenses		592		1,000
Accrued interest		45		32
Accrued expenses and other current liabilities	$	7,275	$	4,528