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STATEMENTS OF CASH FLOWS (USD $)
In Thousands
9 Months Ended
Sep. 30, 2011
Sep. 30, 2010
Operating Activities:  
Net loss$ (15,659)$ (29,423)
Reconciliation of net loss to net cash used in operating activities:  
Change in fair value of warrant liability(1,973)(1,771)
Depreciation and amortization1,197991
Amortization of net premiums on short-term investments317134
Impairment of property and equipment60127
Loss of disposal of property and equipment032
Deferred rent(254)(206)
Non-cash stock-based compensation1,6771,141
Changes in operating assets and liabilities:  
Accounts receivables37(341)
Unbilled receivables(3,848)0
Prepaid expenses and other current assets(1,127)947
Accounts payable and accrued expenses(3,687)1,468
Deferred revenue2,500(143)
Net cash used in operating activities(20,760)(27,044)
Investing Activities:  
Capital expenditures(414)(1,424)
Proceeds from maturities of short-term investments20,23511,000
Purchases of short-term investments(2,082)(27,545)
Net cash provided by (used in) by investing activities17,739(17,969)
Financing Activities:  
Principal payments of notes payable(60)(66)
Net proceeds from sales of common stock, net of offering costs of $0.2 million and $0.4 million, respectively9,18222,114
Proceeds from the exercise of stock options156423
Net cash provided by financing activities9,27822,471
Net increase (decrease) in cash and cash equivalents6,257(22,542)
Cash and cash equivalents at beginning of period8,06138,757
Cash and cash equivalents at end of period14,31816,215
Supplemental disclosure of non-cash activities:  
Equipment purchases included in accounts payable168128
Settlement of notes receivable (See Note 9)$ 1,522$ 0