CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenue:
Revenues	$ 1,981,872,000	$ 1,146,290,000	$ 475,598,000
Expenses:
Cost of sales	902,639,000	0	0
Research and development	1,235,278,000	2,534,508,000	747,027,000
Selling, general, and administrative	488,691,000	298,358,000	145,290,000
Total expenses	2,626,608,000	2,832,866,000	892,317,000
Loss from operations	(644,736,000)	(1,686,576,000)	(416,719,000)
Other income (expense):
Interest expense	(19,880,000)	(21,127,000)	(15,145,000)
Other income (expense)	10,969,000	(6,833,000)	13,605,000
Loss before income tax expense	(653,647,000)	(1,714,536,000)	(418,259,000)
Income tax expense	4,292,000	29,215,000	0
Net loss	$ (657,939,000)	$ (1,743,751,000)	$ (418,259,000)
Net loss per share:
Basic (in usd per share)	$ (8.42)	$ (23.44)	$ (7.27)
Diluted (in usd per share)	$ (8.42)	$ (23.44)	$ (7.27)
Weighted average number of common shares outstanding:
Basic (in shares)	78,183	74,400	57,554
Diluted (in shares)	78,183	74,400	57,554
Product sales
Revenue:
Revenues	$ 1,554,961,000	$ 0	$ 0
Grants
Revenue:
Revenues	382,921,000	948,709,000	453,210,000
Royalties and other
Revenue:
Revenues	$ 43,990,000	$ 197,581,000	$ 22,388,000