CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIT) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Treasury Stock	Accumulated Other Comprehensive Income (Loss)
Balance beginning (in shares) at Dec. 31, 2020		71,350,365
Balance beginning at Dec. 31, 2020	$ 627,209	$ 714	$ 2,535,476	$ (1,874,199)	$ (41,806)	$ 7,024
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	151,457		151,457
Stock issued under incentive programs (in shares)		2,044,191
Issuance of common stock, net of issuance costs	21,441	$ 20	58,747		(37,326)
Issuance of common stock, net of issuance costs (in shares)		2,578,967
Issuance of common stock, net of issuance costs	564,859	$ 26	564,833
Unrealized loss on marketable securities	(9)					(9)
Foreign currency translation adjustment	(6,154)					(6,154)
Net loss	(897,467)			(897,467)
Balance ending (in shares) at Sep. 30, 2021		75,973,523
Balance ending at Sep. 30, 2021	461,336	$ 760	3,310,513	(2,771,666)	(79,132)	861
Balance beginning (in shares) at Jun. 30, 2021		74,672,351
Balance beginning at Jun. 30, 2021	745,562	$ 747	3,237,085	(2,449,235)	(47,205)	4,170
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	45,274		45,274
Stock issued under incentive programs (in shares)		1,301,172
Issuance of common stock, net of issuance costs	(3,760)	$ 13	28,154		(31,927)
Foreign currency translation adjustment	(3,309)					(3,309)
Net loss	(322,431)			(322,431)
Balance ending (in shares) at Sep. 30, 2021		75,973,523
Balance ending at Sep. 30, 2021	461,336	$ 760	3,310,513	(2,771,666)	(79,132)	861
Balance beginning (in shares) at Dec. 31, 2021		76,433,151
Balance beginning at Dec. 31, 2021	(351,673)	$ 764	3,351,967	(3,617,950)	(85,101)	(1,353)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	104,367		104,367
Stock issued under incentive programs (in shares)		573,960
Issuance of common stock, net of issuance costs	67	$ 6	4,900		(4,839)
Issuance of common stock, net of issuance costs (in shares)		2,197,398
Issuance of common stock, net of issuance costs	179,385	$ 22	179,363
Foreign currency translation adjustment	(22,441)					(22,441)
Net loss	(475,690)			(475,690)
Balance ending (in shares) at Sep. 30, 2022		79,204,509
Balance ending at Sep. 30, 2022	(565,985)	$ 792	3,640,597	(4,093,640)	(89,940)	(23,794)
Balance beginning (in shares) at Jun. 30, 2022		78,776,234
Balance beginning at Jun. 30, 2022	(416,950)	$ 788	3,604,614	(3,925,027)	(86,455)	(10,870)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	33,386		33,386
Stock issued under incentive programs (in shares)		428,275
Issuance of common stock, net of issuance costs	(884)	$ 4	2,597		(3,485)
Foreign currency translation adjustment	(12,924)					(12,924)
Net loss	(168,613)			(168,613)
Balance ending (in shares) at Sep. 30, 2022		79,204,509
Balance ending at Sep. 30, 2022	$ (565,985)	$ 792	$ 3,640,597	$ (4,093,640)	$ (89,940)	$ (23,794)