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Stock-Based Compensation - Employee Stock Purchase Plan (Details) - ESPP - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Fair Value        
Risk-free interest rate, minimum 3.20% 0.10% 0.60% 0.10%
Risk-free interest rate, maximum 3.30% 0.20% 3.30% 0.20%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Volatility, minimum 103.00% 114.90% 103.00% 114.90%
Volatility, maximum 114.80% 150.60% 142.90% 159.40%
Minimum        
Fair Value        
Range of Black-Scholes fair values of ESPP shares granted (in usd per share) $ 23.59 $ 83.47 $ 23.59 $ 83.47
Expected term (in years) 6 months 6 months 6 months 6 months
Maximum        
Fair Value        
Range of Black-Scholes fair values of ESPP shares granted (in usd per share) $ 39.73 $ 152.11 $ 79.74 $ 238.85
Expected term (in years) 2 years 2 years 2 years 2 years