Stock-Based Compensation - Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Compensation expense:
Total stock-based compensation expense	$ 31,547	$ 45,274	$ 102,525	$ 151,457
Cost of sales
Compensation expense:
Total stock-based compensation expense	51	0	51	0
Research and development
Compensation expense:
Total stock-based compensation expense	16,107	21,860	52,692	70,429
General and administrative
Compensation expense:
Total stock-based compensation expense	$ 15,389	$ 23,414	$ 49,782	$ 81,028