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Leases (Details)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
ft²
Dec. 31, 2021
USD ($)
Lessee, Lease, Description [Line Items]            
Right of use assets and lease liabilities obtained, operating lease     $ 44,000      
Long-term supply agreement, incremental borrowing rate 5.00%   5.00%      
Short-term lease (benefit) expense $ (46,600) $ 111,300 $ 37,300 $ 325,500    
Research and development 304,297 408,195 977,428 1,571,551    
Lease expense 24,200 4,400   17,100    
Interest expense 900 $ 1,600 4,300 $ 5,600    
Right of use asset, net 108,543   108,543     $ 40,123
700 Quince Orchard Road Agreement            
Lessee, Lease, Description [Line Items]            
Lease expense         $ 5,800  
Facility, number of square feet | ft²         170,000  
Operating lease term         15 years  
Right of use asset, net 73,200   73,200      
Lease obligation 73,200   73,200      
Settlement Agreement            
Lessee, Lease, Description [Line Items]            
Research and development $ 98,300   $ 98,300