CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue:
Revenues	$ 734,577	$ 178,844	$ 1,624,473	$ 924,090
Expenses:
Cost of sales	434,593	0	720,874	0
Research and development	304,297	408,195	977,428	1,571,551
Selling, general, and administrative	122,876	77,793	327,028	214,144
Total expenses	861,766	485,988	2,025,330	1,785,695
Loss from operations	(127,189)	(307,144)	(400,857)	(861,605)
Other expense:
Interest expense	(4,169)	(5,182)	(15,279)	(15,989)
Other expense	(34,783)	(4,064)	(53,002)	(7,267)
Loss before income tax expense	(166,141)	(316,390)	(469,138)	(884,861)
Income tax expense	2,472	6,041	6,552	12,606
Net loss	$ (168,613)	$ (322,431)	$ (475,690)	$ (897,467)
Earnings Per Share [Abstract]
Basic (in usd per share)	$ (2.15)	$ (4.31)	$ (6.13)	$ (12.13)
​Weighted average number of common shares outstanding
Basic (in shares)	78,274	74,745	77,631	73,972
Product sales
Revenue:
Revenues	$ 626,091	$ 0	$ 1,267,174	$ 0
Grants
Revenue:
Revenues	106,273	135,007	313,348	854,390
Royalties and other
Revenue:
Revenues	$ 2,213	$ 43,837	$ 43,951	$ 69,700