Goodwill and Other Intangible Assets - Identifiable Intangible Assets (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Intangible assets:
Amortization expense	$ 100	$ 100
Finite-lived intangible assets:
Gross Carrying Amount	11,618		$ 11,961
Accumulated  Amortization	(7,083)		(7,191)
Intangible Assets, Net	4,535		4,770
Proprietary adjuvant technology
Finite-lived intangible assets:
Gross Carrying Amount	8,004		8,239
Accumulated  Amortization	(3,469)		(3,469)
Intangible Assets, Net	4,535		4,770
Collaboration agreements
Finite-lived intangible assets:
Gross Carrying Amount	3,614		3,722
Accumulated  Amortization	(3,614)		(3,722)
Intangible Assets, Net	$ 0		$ 0