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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenue:      
Revenues $ 1,146,290 $ 475,598 $ 18,662
Expenses:      
Research and development 2,534,508 747,027 113,842
Gain on sale of assets 0 0 (9,016)
General and administrative 298,358 145,290 34,417
Total expenses 2,832,866 892,317 139,243
Loss from operations (1,686,576) (416,719) (120,581)
Other income (expense):      
Investment income 1,364 1,014 1,512
Interest expense (21,127) (15,145) (13,612)
Other income (expense) (8,197) 12,591 (13)
Loss before income tax expense (1,714,536) (418,259) (132,694)
Income tax expense 29,215 0 0
Net loss $ (1,743,751) $ (418,259) $ (132,694)
Earnings per share, basic (USD per share) $ (23.44) $ (7.27) $ (5.51)
Earnings per share, diluted (USD per share) $ (23.44) $ (7.27) $ (5.51)
Weighted average number of shares outstanding, diluted (in shares) 74,400 57,554 24,100
Weighted average number of shares outstanding, basic (in shares) 74,400 57,554 24,100
Grants      
Revenue:      
Revenues $ 948,709 $ 453,210 $ 15,937
Royalties and other      
Revenue:      
Revenues $ 197,581 $ 22,388 $ 2,725