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Income Taxes (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Valuation allowance, deferred tax asset, amount increase (decrease) $ 139,000 $ 28,300
Research Tax Credit Carryforward    
Tax credit carryforward 35,100  
Domestic    
Operating loss carryforwards, subject to expiration 1,300,000  
State and Local Jurisdiction    
Operating loss carryforwards, subject to expiration 756,000  
Foreign    
Operating loss carryforwards, subject to expiration $ 42,700