The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aerojet Rocketdyne Holdings In Common Stock 007800105 4,917 101,825 SH   SOLE   101,825 0 0
AeroVironment Inc Common Stock 008073108 44,520 444,531 SH   SOLE   444,531 0 0
Alibaba Group Holding Ltd ADR 01609W102 104,920 462,651 SH   SOLE   462,651 0 0
Align Technology Inc Common Stock 016255101 7,151 11,703 SH   SOLE   11,703 0 0
Allegheny Technologies Inc Common Stock 01741R102 630 30,238 SH   SOLE   30,238 0 0
Alphabet Inc Common Stock 02079K107 172,538 68,841 SH   SOLE   68,841 0 0
Altair Engineering Inc Common Stock 021369103 27,258 395,210 SH   SOLE   395,210 0 0
Amazon.com Inc Common Stock 023135106 63,756 18,533 SH   SOLE   18,533 0 0
AMETEK Inc Common Stock 031100100 7,121 53,344 SH   SOLE   53,344 0 0
ANSYS Inc Common Stock 03662Q105 61,434 177,014 SH   SOLE   177,014 0 0
AquaBounty Technologies Inc Common Stock 03842K200 36,643 6,836,344 SH   SOLE   6,836,344 0 0
Arcturus Therapeutics Holdings Common Stock 03969T109 97,618 2,884,682 SH   SOLE   2,884,682 0 0
Autodesk Inc Common Stock 052769106 23,774 81,444 SH   SOLE   81,444 0 0
Baidu Inc ADR 056752108 138,700 680,236 SH   SOLE   680,236 0 0
Renishaw PLC Common Stock G75006117 19,785 291,050 SH   SOLE   291,050 0 0
CareDx Inc Common Stock 14167L103 417,707 4,564,110 SH   SOLE   4,564,110 0 0
Carpenter Technology Corp Common Stock 144285103 646 16,058 SH   SOLE   16,058 0 0
Castle Biosciences Inc Common Stock 14843C105 185,203 2,525,613 SH   SOLE   2,525,613 0 0
Cellectis SA ADR 15117K103 72,075 4,659,018 SH   SOLE   4,659,018 0 0
Cerus Corp Common Stock 157085101 123,773 20,942,911 SH   SOLE   19,337,914 616,222 988,775
Codexis Inc Common Stock 192005106 151,275 6,675,879 SH   SOLE   6,675,879 0 0
Deere & Co Common Stock 244199105 87,247 247,363 SH   SOLE   247,363 0 0
DuPont de Nemours Inc Common Stock 26614N102 673 8,695 SH   SOLE   8,695 0 0
Eastman Chemical Co Common Stock 277432100 685 5,864 SH   SOLE   5,864 0 0
Editas Medicine Inc Common Stock 28106W103 406,678 7,180,055 SH   SOLE   6,115,265 846,439 218,351
ExOne Co/The Common Stock 302104104 47,592 2,199,252 SH   SOLE   2,152,905 0 46,347
Facebook Inc Common Stock 30303M102 100,623 289,387 SH   SOLE   289,387 0 0
FARO Technologies Inc Common Stock 311642102 6,610 84,989 SH   SOLE   84,989 0 0
Fate Therapeutics Inc Common Stock 31189P102 649,458 7,483,102 SH   SOLE   7,483,102 0 0
General Electric Co Common Stock 369604103 4,890 363,291 SH   SOLE   363,291 0 0
Grayscale Bitcoin Trust BTC Open-End Fund 389637109 284,916 9,557,723 SH   SOLE   8,822,412 709,918 25,393
Guardant Health Inc Common Stock 40131M109 12 93 SH   SOLE   93 0 0
HDFC Bank Ltd ADR 40415F101 19,106 261,302 SH   SOLE   261,302 0 0
HP Inc Common Stock 40434L105 23,179 767,759 SH   SOLE   767,759 0 0
Hexcel Corp Common Stock 428291108 746 11,955 SH   SOLE   11,955 0 0
Incyte Corp Common Stock 45337C102 248,097 2,948,967 SH   SOLE   2,948,967 0 0
Intellia Therapeutics Inc Common Stock 45826J105 1,244,188 7,684,441 SH   SOLE   6,354,596 1,022,687 307,158
Intercontinental Exchange Inc Common Stock 45866F104 100,892 849,974 SH   SOLE   801,914 7,249 40,811
Intuit Inc Common Stock 461202103 71,192 145,240 SH   SOLE   145,240 0 0
Intuitive Surgical Inc Common Stock 46120E602 48,013 52,209 SH   SOLE   52,209 0 0
OC Oerlikon Corp AG Common Stock H59187106 4,705 424,447 SH   SOLE   424,447 0 0
Invitae Corp Common Stock 46185L103 721,830 21,400,230 SH   SOLE   18,185,631 2,403,826 810,773
Ionis Pharmaceuticals Inc Common Stock 462222100 355,329 8,907,733 SH   SOLE   8,907,733 0 0
Iovance Biotherapeutics Inc Common Stock 462260100 480,088 18,450,713 SH   SOLE   17,619,669 521,169 309,875
Iridium Communications Inc Common Stock 46269C102 543,583 13,592,982 SH   SOLE   12,593,288 789,492 210,202
JD.com Inc ADR 47215P106 500,785 6,274,717 SH   SOLE   6,274,717 0 0
SGL Carbon SE Common Stock D6949M108 848 89,002 SH   SOLE   89,002 0 0
Kaiser Aluminum Corp Common Stock 483007704 5,340 43,239 SH   SOLE   43,239 0 0
Komatsu Ltd ADR 500458401 69,785 2,813,892 SH   SOLE   2,813,892 0 0
Kratos Defense & Security Solu Common Stock 50077B207 237,767 8,345,637 SH   SOLE   8,345,637 0 0
Henkel AG & Co KGaA Preference D3207M110 608 5,757 SH   SOLE   5,757 0 0
Bertrandt AG Common Stock D1014N107 5,754 87,340 SH   SOLE   87,340 0 0
LendingClub Corp Common Stock 52603A208 127,920 7,055,731 SH   SOLE   6,253,643 183,369 618,719
LendingTree Inc Common Stock 52603B107 1 6 SH   SOLE   6 0 0
Dassault Systemes SE Common Stock F2457H472 43,192 178,251 SH   SOLE   178,251 0 0
Lincoln Electric Holdings Inc Common Stock 533900106 5,271 40,018 SH   SOLE   40,018 0 0
Siemens AG Common Stock D69671218 4,673 29,386 SH   SOLE   29,386 0 0
Materialise NV ADR 57667T100 149,106 6,189,551 SH   SOLE   5,925,365 75,126 189,060
MercadoLibre Inc Common Stock 58733R102 189,304 121,521 SH   SOLE   121,521 0 0
Microsoft Corp Common Stock 594918104 25,411 93,801 SH   SOLE   93,801 0 0
Bezeq The Israeli Telecommunic Common Stock M2012Q100 5,770 5,301,698 SH   SOLE   5,301,698 0 0
Moog Inc Common Stock 615394202 4,807 57,181 SH   SOLE   57,181 0 0
Danel Adir Yeoshua Ltd Common Stock M27013107 6,472 30,909 SH   SOLE   30,909 0 0
Hilan Ltd Common Stock M5299H123 5,204 107,986 SH   SOLE   107,986 0 0
Nano Dimension Ltd ADR 63008G203 134,906 16,372,053 SH   SOLE   16,372,053 0 0
NanoString Technologies Inc Common Stock 63009R109 193,588 2,987,927 SH   SOLE   2,895,156 92,771 0
Elbit Systems Ltd Common Stock M3760D101 47,703 367,657 SH   SOLE   367,657 0 0
Partner Communications Co Ltd Common Stock M78465107 5,593 1,222,658 SH   SOLE   1,222,658 0 0
Netflix Inc Common Stock 64110L106 58,934 111,573 SH   SOLE   111,573 0 0
Nice Ltd ADR 653656108 5,901 23,846 SH   SOLE   23,846 0 0
NVIDIA Corp Common Stock 67066G104 53,779 67,215 SH   SOLE   67,215 0 0
NuVasive Inc Common Stock 670704105 4,840 71,410 SH   SOLE   71,410 0 0
Matrix IT Ltd Common Stock M6859E153 5,845 216,365 SH   SOLE   216,365 0 0
Toray Industries Inc Common Stock J89494116 714 107,308 SH   SOLE   107,308 0 0
PTC Inc Common Stock 69370C100 23,303 164,968 SH   SOLE   164,968 0 0
Pacific Biosciences of Califor Common Stock 69404D108 716,238 20,481,486 SH   SOLE   19,944,091 304,665 232,730
One Software Technologies Ltd Common Stock M75260113 6,429 429,180 SH   SOLE   429,180 0 0
PayPal Holdings Inc Common Stock 70450Y103 281,463 965,633 SH   SOLE   965,633 0 0
Personalis Inc Common Stock 71535D106 125,032 4,941,964 SH   SOLE   4,941,964 0 0
Straumann Holding AG Common Stock H8300N119 30,507 19,142 SH   SOLE   19,142 0 0
Pinduoduo Inc ADR 722304102 195,643 1,540,252 SH   SOLE   1,540,252 0 0
Pinterest Inc Common Stock 72352L106 130,721 1,655,743 SH   SOLE   1,655,743 0 0
Pluristem Therapeutics Inc Common Stock 72940R300 5,350 1,350,921 SH   SOLE   1,350,921 0 0
Proto Labs Inc Common Stock 743713109 278,212 3,030,630 SH   SOLE   2,541,588 350,104 138,938
Redhill Biopharma Ltd ADR 757468103 5,418 787,469 SH   SOLE   787,469 0 0
Roku Inc Common Stock 77543R102 2,177,585 4,741,612 SH   SOLE   4,256,384 379,155 106,073
Charles Schwab Corp/The Common Stock 808513105 36,054 495,180 SH   SOLE   495,180 0 0
Seres Therapeutics Inc Common Stock 81750R102 231,659 9,713,160 SH   SOLE   8,376,063 1,039,948 297,149
Shopify Inc Common Stock 82509L107 1,781,399 1,219,318 SH   SOLE   1,126,532 73,907 18,879
Snap Inc Common Stock 83304A106 150,907 2,214,665 SH   SOLE   2,214,665 0 0
Splunk Inc Common Stock 848637104 62,076 429,357 SH   SOLE   429,357 0 0
Square Inc Common Stock 852234103 1,959,995 8,039,354 SH   SOLE   7,389,737 498,023 151,594
Stryker Corp Common Stock 863667101 4,984 19,190 SH   SOLE   19,190 0 0
Taiwan Semiconductor Manufactu ADR 874039100 1 10 SH   SOLE   10 0 0
Teladoc Health Inc Common Stock 87918A105 2,663,467 16,016,998 SH   SOLE   14,885,372 869,875 261,751
Tencent Holdings Ltd ADR 88032Q109 452,095 6,003,916 SH   SOLE   5,655,590 293,074 55,252
Teradyne Inc Common Stock 880770102 372,987 2,784,316 SH   SOLE   2,655,097 78,742 50,477
Tesla Inc Common Stock 88160R101 3,693,287 5,433,702 SH   SOLE   5,042,773 387,875 3,054
Teva Pharmaceutical Industries ADR 881624209 5,073 512,442 SH   SOLE   512,442 0 0
Trade Desk Inc/The Common Stock 88339J105 168,684 2,180,502 SH   SOLE   2,180,502 0 0
3D Systems Corp Common Stock 88554D205 159,219 3,983,451 SH   SOLE   3,983,451 0 0
3M Co Common Stock 88579Y101 657 3,309 SH   SOLE   3,309 0 0
Trimble Inc Common Stock 896239100 430,294 5,258,393 SH   SOLE   5,121,920 83,419 53,054
Twilio Inc Common Stock 90138F102 1,467,300 3,722,599 SH   SOLE   3,390,742 265,901 65,956
Twist Bioscience Corp Common Stock 90184D100 673,561 5,054,864 SH   SOLE   4,837,420 110,896 106,548
2U Inc Common Stock 90214J101 390,953 9,382,118 SH   SOLE   8,051,689 932,994 397,435
Ultra Clean Holdings Inc Common Stock 90385V107 4,828 89,874 SH   SOLE   89,874 0 0
United Parcel Service Inc Common Stock 911312106 5,702 27,419 SH   SOLE   27,419 0 0
Veracyte Inc Common Stock 92337F107 267,437 6,689,263 SH   SOLE   6,515,408 173,855 0
Workday Inc Common Stock 98138H101 67,783 283,920 SH   SOLE   283,920 0 0
Xerox Holdings Corp Common Stock 98421M106 636 27,094 SH   SOLE   27,094 0 0
Zillow Group Inc Common Stock 98954M200 1,240,545 10,150,100 SH   SOLE   9,263,853 683,124 203,123
Koninklijke DSM NV Common Stock N5017D122 704 3,775 SH   SOLE   3,775 0 0
Arkema SA Common Stock F0392W125 671 5,355 SH   SOLE   5,355 0 0
MGI Digital Graphic Technology Common Stock F4090S113 23,619 431,454 SH   SOLE   431,454 0 0
Sandvik AB Common Stock W74857165 609 23,862 SH   SOLE   23,862 0 0
Cellcom Israel Ltd Common Stock M2196U109 6,757 1,555,351 SH   SOLE   1,555,351 0 0
Evonik Industries AG Common Stock D2R90Y117 620 18,439 SH   SOLE   18,439 0 0
Fattal Holdings 1998 Ltd Common Stock M4148G105 5,234 55,087 SH   SOLE   55,087 0 0
Meituan Common Stock G59669104 128,394 3,112,230 SH   SOLE   3,112,230 0 0
SLM Solutions Group AG Common Stock D6T690109 31,029 1,179,582 SH   SOLE   1,179,582 0 0
ZhongAn Online P&C Insurance C Common Stock Y989DF109 78,347 13,844,663 SH   SOLE   13,844,663 0 0
Adyen NV Common Stock N3501V104 128,220 52,517 SH   SOLE   52,517 0 0
Medtronic PLC Common Stock G5960L103 4,857 39,131 SH   SOLE   39,131 0 0
Sapiens International Corp NV Common Stock G7T16G103 4,459 169,723 SH   SOLE   169,723 0 0
CRISPR Therapeutics AG Common Stock H17182108 1,258,876 7,776,119 SH   SOLE   6,975,011 611,472 189,636
Spotify Technology SA Common Stock L8681T102 1,320,629 4,792,008 SH   SOLE   4,337,851 342,270 111,887
Allot Ltd Common Stock M0854Q105 6,369 321,159 SH   SOLE   321,159 0 0
AudioCodes Ltd Common Stock M15342104 5,952 179,866 SH   SOLE   179,866 0 0
Camtek Ltd/Israel Common Stock M20791105 6,301 167,088 SH   SOLE   167,088 0 0
Ceragon Networks Ltd Common Stock M22013102 5,759 1,527,459 SH   SOLE   1,527,459 0 0
Check Point Software Technolog Common Stock M22465104 5,552 47,812 SH   SOLE   47,812 0 0
Compugen Ltd Common Stock M25722105 99,158 11,975,607 SH   SOLE   11,623,545 219,844 132,218
CyberArk Software Ltd Common Stock M2682V108 5,107 39,203 SH   SOLE   39,203 0 0
Evogene Ltd - ADR Common Stock M4119S104 11,421 3,339,463 SH   SOLE   3,339,463 0 0
Evogene Ltd Common Stock M4119S104 2,935 853,880 SH   SOLE   853,880 0 0
Fiverr International Ltd Common Stock M4R82T106 6,110 25,198 SH   SOLE   25,198 0 0
Ituran Location and Control Lt Common Stock M6158M104 7,100 260,656 SH   SOLE   260,656 0 0
Nova Measuring Instruments Ltd Common Stock M7516K103 6,049 58,793 SH   SOLE   58,793 0 0
Radware Ltd Common Stock M81873107 6,060 196,887 SH   SOLE   196,887 0 0
Stratasys Ltd Common Stock M85548101 229,434 8,872,166 SH   SOLE   6,753,950 1,419,697 698,519
Taro Pharmaceutical Industries Common Stock M8737E108 5,512 76,598 SH   SOLE   76,598 0 0
Tower Semiconductor Ltd Common Stock M87915274 5,525 187,735 SH   SOLE   187,735 0 0
UroGen Pharma Ltd Common Stock M96088105 4,829 316,248 SH   SOLE   316,248 0 0
Wix.com Ltd Common Stock M98068105 5,585 19,240 SH   SOLE   19,240 0 0
NXP Semiconductors NV Common Stock N6596X109 69,162 336,196 SH   SOLE   336,196 0 0
DocuSign Inc Common Stock 256163106 784,750 2,806,990 SH   SOLE   2,675,930 95,637 35,423
Discovery Ltd Common Stock S2192Y109 45,252 5,130,848 SH   SOLE   5,130,848 0 0
Inmode Ltd Common Stock M5425M103 6,321 66,761 SH   SOLE   66,761 0 0
Perion Network Ltd Common Stock M78673114 7,050 329,119 SH   SOLE   329,119 0 0
Silvergate Capital Corp Common Stock 82837P408 79,418 700,831 SH   SOLE   700,831 0 0
Meituan ADR 58533E103 202 2,453 SH   SOLE   2,453 0 0
Z Holdings Corp Common Stock J9894K105 92,735 18,502,126 SH   SOLE   18,502,126 0 0
Sea Ltd ADR 81141R100 777,095 2,829,917 SH   SOLE   2,623,634 160,115 46,168
Z Holdings Corp ADR 98877X101 193 19,440 SH   SOLE   19,440 0 0
Pure Storage Inc Common Stock 74624M102 297,918 15,254,370 SH   SOLE   13,670,280 1,158,855 425,235
Synopsys Inc Common Stock 871607107 43,308 157,033 SH   SOLE   157,033 0 0
HUYA Inc ADR 44852D108 56,203 3,184,322 SH   SOLE   3,184,322 0 0
RADA Electronic Industries Ltd Common Stock M81863124 5,172 424,628 SH   SOLE   424,628 0 0
PagerDuty Inc Common Stock 69553P100 365,916 8,593,607 SH   SOLE   7,444,434 869,254 279,919
Caterpillar Inc Common Stock 149123101 53,277 244,806 SH   SOLE   244,806 0 0
Arconic Corp Common Stock 03966V107 6,388 179,345 SH   SOLE   179,345 0 0
Adaptive Biotechnologies Corp Common Stock 00650F109 178,435 4,366,977 SH   SOLE   4,366,977 0 0
10X Genomics Inc Common Stock 88025U109 842,033 4,300,037 SH   SOLE   3,900,767 315,937 83,333
Bitcoin Fund/The Closed-End Fund 09175G104 10,315 279,234 SH   SOLE   0 0 279,234
Schrodinger Inc/United States Common Stock 80810D103 197,465 2,611,626 SH   SOLE   2,611,626 0 0
Slack Technologies Inc Common Stock 83088V102 6 126 SH   SOLE   126 0 0
TCS Group Holding PLC GDR 87238U203 73,434 839,243 SH   SOLE   839,243 0 0
Phreesia Inc Common Stock 71944F106 0 7 SH   SOLE   7 0 0
Adyen NV ADR 00783V104 59,272 1,206,182 SH   SOLE   1,206,182 0 0
Cie Generale des Etablissement Common Stock F61824144 5,305 33,289 SH   SOLE   33,289 0 0
voestalpine AG Common Stock A9101Y103 619 15,220 SH   SOLE   15,220 0 0
Yeahka Ltd Common Stock G9835C108 54,254 8,625,600 SH   SOLE   8,625,600 0 0
Accolade Inc Common Stock 00437E102 294,198 5,417,006 SH   SOLE   5,417,006 0 0
Berkeley Lights Inc Common Stock 084310101 309,333 6,903,209 SH   SOLE   6,903,209 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100 357,705 1,774,066 SH   SOLE   1,774,066 0 0
BYD Co Ltd ADR 05606L100 51,760 861,526 SH   SOLE   861,526 0 0
Kamada Ltd Common Stock M6240T109 5,358 915,006 SH   SOLE   915,006 0 0
BATM Advanced Communications L Common Stock M19199112 5,237 4,287,584 SH   SOLE   4,287,584 0 0
Gamida Cell Ltd Common Stock M47364100 4,417 689,129 SH   SOLE   689,129 0 0
Gilat Satellite Networks Ltd Common Stock M51474118 5,659 555,902 SH   SOLE   555,902 0 0
PolyPid Ltd Common Stock M8001Q118 5,482 605,382 SH   SOLE   605,382 0 0
Silicom Ltd Common Stock M84116108 5,466 124,047 SH   SOLE   124,047 0 0
Nintendo Co Ltd ADR 654445303 379,636 5,234,196 SH   SOLE   4,662,598 455,213 116,385
Organovo Holdings Inc Common Stock 68620A203 4,022 427,833 SH   SOLE   424,305 3,528 0
Surface Oncology Inc Common Stock 86877M209 33,410 4,478,546 SH   SOLE   4,478,546 0 0
Takeda Pharmaceutical Co Ltd ADR 874060205 260,747 15,492,997 SH   SOLE   15,492,997 0 0
Niu Technologies ADR 65481N100 74,864 2,292,934 SH   SOLE   2,292,934 0 0
Thermo Fisher Scientific Inc Common Stock 883556102 662 1,312 SH   SOLE   1,312 0 0
Exact Sciences Corp Common Stock 30063P105 1,333,447 10,726,790 SH   SOLE   9,850,261 698,179 178,350
Snowflake Inc Common Stock 833445109 24 98 SH   SOLE   98 0 0
Unity Software Inc Common Stock 91332U101 1,297,116 11,810,212 SH   SOLE   10,822,501 753,861 233,850
Beam Therapeutics Inc Common Stock 07373V105 831,643 6,461,367 SH   SOLE   6,461,367 0 0
Novartis AG Common Stock H5820Q150 389,457 4,274,698 SH   SOLE   4,186,770 45,229 42,699
Regeneron Pharmaceuticals Inc Common Stock 75886F107 398,266 713,048 SH   SOLE   713,048 0 0
Repare Therapeutics Inc Common Stock 760273102 63,207 2,027,160 SH   SOLE   2,027,160 0 0
KE Holdings Inc ADR 482497104 276,607 5,801,313 SH   SOLE   5,599,125 130,578 71,610
Cloudflare Inc Common Stock 18915M107 64,948 613,639 SH   SOLE   613,639 0 0
Palantir Technologies Inc Common Stock 69608A108 808,772 30,681,798 SH   SOLE   27,860,855 2,168,398 652,545
Raven Industries Inc Common Stock 754212108 47,941 828,704 SH   SOLE   828,704 0 0
Zoom Video Communications Inc Common Stock 98980L101 1,419,861 3,668,607 SH   SOLE   3,385,820 212,368 70,419
Honeywell International Inc Common Stock 438516106 6,820 31,092 SH   SOLE   31,092 0 0
Alphabet Inc Common Stock 02079K305 7 3 SH   SOLE   3 0 0
Roche Holding AG ADR 771195104 235,070 5,002,547 SH   SOLE   5,002,547 0 0
Sarepta Therapeutics Inc Common Stock 803607100 39,215 504,442 SH   SOLE   504,442 0 0
Opendoor Technologies Inc Common Stock 683712103 179,769 10,139,232 SH   SOLE   10,139,232 0 0
BASE Inc Common Stock J0433G101 40,050 2,634,200 SH   SOLE   2,634,200 0 0
Kaspi.KZ JSC GDR 48581R205 24,563 231,722 SH   SOLE   231,722 0 0
908 Devices Inc Common Stock 65443P102 95,106 2,454,357 SH   SOLE   2,454,357 0 0
Magna International Inc Common Stock 559222401 50,958 550,068 SH   SOLE   550,068 0 0
Peloton Interactive Inc Common Stock 70614W100 209,425 1,688,639 SH   SOLE   1,688,639 0 0
Veeva Systems Inc Common Stock 922475108 272,264 875,589 SH   SOLE   875,589 0 0
Grayscale Ethereum Trust Open-End Fund 389638107 16,150 721,936 SH   SOLE   0 721,936 0
Bristol-Myers Squibb Co Common Stock 110122108 127,148 1,902,838 SH   SOLE   1,902,838 0 0
SPDR S&P 500 ETF Trust ETP 78462F103 6 14 SH   SOLE   14 0 0
1Life Healthcare Inc Common Stock 68269G107 107,614 3,255,103 SH   SOLE   3,255,103 0 0
PyroGenesis Canada Inc Common Stock 74734T104 666 127,521 SH   SOLE   127,521 0 0
Arad Ltd Common Stock M1492B104 5,258 388,109 SH   SOLE   388,109 0 0
Augwind Energy Tech Storage Lt Common Stock M6058P108 4,428 212,501 SH   SOLE   212,501 0 0
Bet Shemesh Engines Holdings 1 Common Stock M20119109 5,172 257,562 SH   SOLE   257,562 0 0
Electra Consumer Products 1970 Common Stock M3798N105 7,002 121,947 SH   SOLE   121,947 0 0
E&M Computing Ltd Common Stock M4026X105 5,317 809,346 SH   SOLE   809,346 0 0
Intercure Ltd Common Stock M549GJ111 4,579 642,714 SH   SOLE   642,714 0 0
Itamar Medical Ltd Common Stock M61483109 5,674 7,201,116 SH   SOLE   7,201,116 0 0
Magic Software Enterprises Ltd Common Stock 559166103 5,597 346,820 SH   SOLE   346,820 0 0
Malam - Team Ltd Common Stock M87437105 6,450 188,192 SH   SOLE   188,192 0 0
Plasson Industries Ltd Common Stock M7933B108 6,204 112,303 SH   SOLE   112,303 0 0
RoboGroup T E K Ltd Common Stock M20330102 4,819 3,313,095 SH   SOLE   3,313,095 0 0
Desktop Metal Inc Common Stock 25058X105 21,483 1,868,070 SH   SOLE   1,868,070 0 0
DarioHealth Corp Common Stock 23725P209 6,410 300,092 SH   SOLE   300,092 0 0
Enlivex Therapeutics Ltd Common Stock M4130Y106 4,582 514,807 SH   SOLE   514,807 0 0
JFrog Ltd Common Stock M6191J100 4,884 107,301 SH   SOLE   107,301 0 0
Eastman Kodak Co Common Stock 277461406 768 92,313 SH   SOLE   92,313 0 0
Kornit Digital Ltd Common Stock M6372Q113 6,682 53,745 SH   SOLE   53,745 0 0
Lockheed Martin Corp Common Stock 539830109 109,732 290,028 SH   SOLE   290,028 0 0
Nano-X Imaging Ltd Common Stock M70700105 4,958 154,711 SH   SOLE   154,711 0 0
PACCAR Inc Common Stock 693718108 26,965 302,131 SH   SOLE   302,131 0 0
SolarEdge Technologies Inc Common Stock 83417M104 5,792 20,959 SH   SOLE   20,959 0 0
Skillz Inc Common Stock 83067L109 534,396 24,603,886 SH   SOLE   23,469,279 683,174 451,433
Teledyne Technologies Inc Common Stock 879360105 43,263 103,295 SH   SOLE   103,295 0 0
Twitter Inc Common Stock 90184L102 854,351 12,416,085 SH   SOLE   11,389,900 819,674 206,511
AbbVie Inc Common Stock 00287Y109 61,548 546,411 SH   SOLE   546,411 0 0
Butterfly Network Inc Common Stock 124155102 114,843 7,931,137 SH   SOLE   7,931,137 0 0
CM Life Sciences Inc Common Stock 18978W109 64,214 4,583,442 SH   SOLE   4,583,442 0 0
Signify Health Inc Common Stock 82671G100 122,226 4,016,621 SH   SOLE   4,016,621 0 0
ARK Innovation ETF ETP 00214Q104 3,059 23,389 SH   SOLE   23,389 0 0
Ping An Healthcare and Technol Common Stock G71139102 72,434 5,817,500 SH   SOLE   5,817,500 0 0
Bill.com Holdings Inc Common Stock 090043100 41,043 224,060 SH   SOLE   224,060 0 0
DraftKings Inc Common Stock 26142R104 710,986 13,628,251 SH   SOLE   12,529,452 860,698 238,101
Atlas Crest Investment Corp Common Stock 049284102 33,672 3,380,765 SH   SOLE   3,380,765 0 0
One Common Stock G7000X105 21,362 2,140,432 SH   SOLE   2,140,432 0 0
Vuzix Corp Common Stock 92921W300 79,310 4,322,093 SH   SOLE   4,322,093 0 0
ARK Genomic Revolution ETF ETP 00214Q302 776 8,391 SH   SOLE   8,391 0 0
Seer Inc Common Stock 81578P106 49,462 1,508,918 SH   SOLE   1,508,918 0 0
iShares Russell 1000 Growth ET ETP 464287614 28 104 SH   SOLE   104 0 0
Airbus SE Common Stock N0280G100 8,945 69,618 SH   SOLE   69,618 0 0
Thales SA Common Stock F9156M108 24,654 241,827 SH   SOLE   241,827 0 0
Komatsu Ltd Common Stock J35759125 22,257 895,688 SH   SOLE   895,688 0 0
Boeing Co/The Common Stock 097023105 17,741 74,056 SH   SOLE   74,056 0 0
Garmin Ltd Common Stock H2906T109 6,398 44,236 SH   SOLE   44,236 0 0
HEICO Corp Common Stock 422806109 6,245 44,790 SH   SOLE   44,790 0 0
L3Harris Technologies Inc Common Stock 502431109 32,512 150,416 SH   SOLE   150,416 0 0
The 3D Printing ETF ETP 00214Q500 43,593 1,095,858 SH   SOLE   1,095,858 0 0
ROBLOX Corp Common Stock 771049103 87,065 967,608 SH   SOLE   967,608 0 0
Reinvent Technology Partners Common Stock G7483N129 11,885 1,190,925 SH   SOLE   1,190,925 0 0
Jaws Spitfire Acquisition Corp Common Stock G50740102 34,535 3,450,052 SH   SOLE   3,450,052 0 0
Spirit AeroSystems Holdings In Common Stock 848574109 16,335 346,164 SH   SOLE   346,164 0 0
UiPath Inc Common Stock 90364P105 806,729 11,875,886 SH   SOLE   11,400,688 295,034 180,164
Coinbase Global Inc Common Stock 19260Q107 1,422,891 5,617,415 SH   SOLE   5,123,079 386,495 107,841
TuSimple Holdings Inc Common Stock 90089L108 461,118 6,472,735 SH   SOLE   5,544,203 787,624 140,908
CM Life Sciences II Inc Unit 125842203 38,313 2,848,522 SH   SOLE   2,848,522 0 0
Recursion Pharmaceuticals Inc Common Stock 75629V104 86,822 2,378,675 SH   SOLE   2,378,675 0 0
Zymergen Inc Common Stock 98985X100 43,939 1,098,211 SH   SOLE   1,098,211 0 0
Galileo Acquisition Corp Common Stock G3770A102 5 466 SH   SOLE   466 0 0
Okta Inc Common Stock 679295105 89,528 365,899 SH   SOLE   365,899 0 0
Blade Air Mobility Inc Common Stock 092667104 41,299 3,933,232 SH   SOLE   3,933,232 0 0
JD Logistics Inc Common Stock G5074S101 28,951 5,315,408 SH   SOLE   5,315,408 0 0
Hexagon AB Common Stock W4R431112 7,375 497,855 SH   SOLE   497,855 0 0
StoneCo Ltd Common Stock G85158106 39,268 585,570 SH   SOLE   585,570 0 0
Dicerna Pharmaceuticals Inc Common Stock 253031108 12,257 328,441 SH   SOLE   328,441 0 0
Dynamics Special Purpose Corp Common Stock 268010105 20,740 2,086,512 SH   SOLE   2,086,512 0 0
Walt Disney Co/The Common Stock 254687106 26,788 152,406 SH   SOLE   152,406 0 0
Quantum-Si Inc Common Stock 74765K105 49,632 4,048,303 SH   SOLE   4,048,303 0 0
Verve Therapeutics Inc Common Stock 92539P101 33,040 548,389 SH   SOLE   548,389 0 0
Kanzhun Ltd ADR 48553T106 41,586 1,048,822 SH   SOLE   1,048,822 0 0
Etsy Inc Common Stock 29786A106 72,748 353,421 SH   SOLE   353,421 0 0