SEC FORM 3

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

Weber David A

(Last)

(First)

(Middle)

C/O AFFYMETRIX, INC.

3420 CENTRAL EXPRESSWAY

(Street)

SANTA CLARA

95051

(City)

(State)

(Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
02/12/2013

3. Issuer Name and Ticker or Trading Symbol
AFFYMETRIX INC [ AFFX ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	EVP, Commercial Operations

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock⁽¹⁾	55,750⁽²⁾	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
Option to Purchase Common Stock	⁽³⁾	12/15/2018	Common Stock	90,000	$3.86	D
Option to Purchase Common Stock	⁽⁴⁾	02/14/2020	Common Stock	50,000	$3.84	D

Explanation of Responses:

1. This Form 3 does not include 50,000 performance-based restricted stock untits granted on February 14, 2013. These shares will be reported on subsequent Form 4s if and when the performance criteria are met.

2. Includes (1) 25,000 restricted stock units granted on December 15, 2011 and 30,000 restricted stock units granted on February 14, 2013 (each restricted stock unit grant vests in equal annual installments over four years from the grant date) and (2) 750 shares purchased through the Employee Stock Purchase Plan of Affymetrix, Inc. on November 14, 2012.

3. Stock option becomes exercisable in equal annual installments over four years from the grant date of December 15, 2011.

4. Stock option becomes exercisable in equal annual installments over four years from the grant date of February 14, 2013.

Remarks:

	/s/ Siang H. Chin, Attorney-in-Fact for David Weber	02/19/2013
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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