S-1 1 y91150sv1.htm FORM S-1 sv1
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As filed with the Securities and Exchange Commission on May 23, 2011
Registration No. 333-          
 
 
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
 
 
 
 
Form S-1
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
 
 
 
 
CERES, INC.
(Exact name of registrant as specified in its charter)
 
 
 
 
         
Delaware
(State or other jurisdiction of
incorporation or organization)
  100
(Primary Standard Industrial
Classification Code Number)
  33-0727287
(I.R.S. Employer
Identification Number)
 
1535 Rancho Conejo Boulevard
Thousand Oaks, CA 91320
(805) 376-6500
(Address, including zip code, and telephone number, including area code, of Registrant’s principal executive offices)
 
 
 
 
Richard Hamilton
President and Chief Executive Officer
Ceres, Inc.
1535 Rancho Conejo Boulevard
Thousand Oaks, CA 91320
Telephone: (805) 376-6500
Facsimile: (805) 498-1002
(Name, address, including zip code, and telephone number, including area code, of agent for service)
 
 
 
 
Copies to:
 
     
Danielle Carbone, Esq.
Shearman & Sterling LLP
599 Lexington Avenue
New York, New York 10022
Telephone: (212) 848-4000
Facsimile: (212) 848-7179
  Kevin P. Kennedy, Esq.
Simpson Thacher & Bartlett LLP
2550 Hanover Street
Palo Alto, California 94304
Telephone: (650) 251-5130
Facsimile: (650) 251-5002
 
 
 
 
Approximate date of commencement of proposed sale to the public:  As soon as practicable after the effective date of this Registration Statement.
 
If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box.  o
 
If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  o
 
If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  o
 
If this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  o
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer”, “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):
Large accelerated filer o Accelerated filer o Non-accelerated filer þ Smaller reporting company o
(Do not check if a smaller reporting company)
 
 
 
 
CALCULATIONS OF REGISTRATION FEE
 
                     
      Proposed Maximum
    Amount of
Title of Each Class of
    Aggregate
    Registration
Securities to be Registered     Offering Price(1)     Fee(1)
Common Stock, $0.01 par value
    $ 100,000,000       $ 11,610  
                     
 
(1) Estimated solely for the purpose of computing the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933. Includes the offering price of additional shares that the underwriters have the option to purchase.
 
The Registrant hereby amends this Registration Statement on such date or dates as may be necessary to delay its effective date until the Registrant shall file a further amendment which specifically states that this Registration Statement shall thereafter become effective in accordance with Section 8(a) of the Securities Act of 1933 or until the Registration Statement shall become effective on such date as the Commission, acting pursuant to said Section 8(a), may determine.
 


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The information in this preliminary prospectus is not complete and may be changed. These securities may not be sold until the registration statement filed with the Securities and Exchange Commission is effective. This preliminary prospectus is not an offer to sell nor does it seek an offer to buy these securities in any jurisdiction where the offer or sale is not permitted.
 
Subject to Completion. Dated May 23, 2011.
 
           Shares
 
(CERES LOGO)
 
Common Stock
 
 
 
 
This is an initial public offering of shares of common stock of Ceres, Inc. All of the       shares of common stock are being sold by the Company.
 
Prior to this offering, there has been no public market for the common stock. It is currently estimated that the initial public offering price per share will be between $      and $      . We intend to apply to list our common stock on the Nasdaq Global Market under the symbol “CERE”.
 
See “Risk Factors” on page 11 to read about factors you should consider before buying shares of the common stock.
 
 
 
 
Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.
 
 
 
 
                 
    Per Share     Total  
 
Initial public offering price
  $             $          
Underwriting discount
  $       $    
Proceeds, before expenses, to Ceres
  $       $  
 
To the extent that the underwriters sell more than           shares of common stock, the underwriters have the option to purchase up to an additional           shares from Ceres at the initial public offering price less the underwriting discount.
 
 
 
 
The underwriters expect to deliver the shares against payment in New York, New York on          , 2011.
 
Goldman, Sachs & Co. Barclays Capital
 
 
 
 
Prospectus dated          , 2011.


 

 
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 EX-23.1
 
 
 
 
Through and including          , 2011 (the 25th day after the date of this prospectus), all dealers effecting transactions in these securities, whether or not participating in this offering, may be required to deliver a prospectus. This is in addition to a dealer’s obligation to deliver a prospectus when acting as an underwriter and with respect to an unsold allotment or subscription.
 
 
 
 
We have not, and the underwriters and their affiliates have not, authorized anyone to provide you with any information or to make any representation not contained in this prospectus. We do not, and the underwriters and their affiliates do not, take any responsibility for, and can provide no assurance as to the reliability of, any information that others may provide to you. This prospectus is not an offer to sell or an offer to buy shares of our common stock in any jurisdiction where offers and sales are not permitted. The information in this prospectus is accurate only as of the date of this prospectus, regardless of the time of delivery of this prospectus or any sale of shares of our common stock.
 
Neither we nor any of the underwriters have done anything that would permit a public offering of the shares of our common stock or possession or distribution of this prospectus in any jurisdiction where action for that purpose is required, other than in the United States. Persons outside the United States who come into possession of this prospectus must inform themselves about, and observe any restrictions relating to, the offering of the shares of common stock and the distribution of this prospectus outside of the United States.


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PROSPECTUS SUMMARY
 
This summary highlights information contained elsewhere in this prospectus and does not contain all of the information you should consider in making your investment decision. You should read this summary together with the more detailed information, including our financial statements and the related notes, contained in this prospectus. You should carefully consider, among other things, the matters discussed in “Risk Factors”, before making an investment decision. Unless otherwise indicated in this prospectus, “Ceres”, “our company”, “the Company”, “we”, “us” and “our” refer to Ceres, Inc. and our subsidiary, Ceres Sementes do Brasil Ltda.
 
Business Overview
 
Our Company
 
We are an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks that can enable the large-scale replacement of petroleum and other fossil fuels. We use a combination of advanced plant breeding and biotechnology to develop new crops, known as dedicated energy crops, that we believe address the limitations of first-generation bioenergy feedstocks, such as corn and sugarcane, increase biomass productivity, reduce crop inputs and improve cultivation on marginal land.
 
Our first large-scale commercial products are proprietary sweet sorghum varieties that can be used as a “drop-in” feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills, the operating days of which are currently limited due to the inherent limitations of sugarcane physiology and growth patterns. Our dedicated energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Finally, baseload utility-scale electric power can also be generated from the biomass feedstocks grown from our seeds.
 
The seed industry has historically required very little capital to manufacture seeds, and seeds have typically been sold at prices that generate high gross margins. As a producer of proprietary seeds, we believe we are in the most attractive segment of the bioenergy value chain — upstream from the capital intensive refining and conversion of biomass. For example, in 2009 corn seed providers maintained high margins when volatile commodity prices significantly impacted corn ethanol refining margins. Therefore, we believe our success is tied to adoption of our products rather than the relative profitability of downstream participants. Our upstream position in the value chain also allows us to be largely independent of the success of any particular conversion technology or end use.
 
Our Technology
 
We develop low input dedicated energy crops capable of producing high yields of biomass per acre using innovative plant breeding and trait biotechnology. By developing these types of crops, we enable the scalable, sustainable and economic production of bioenergy, or the energy derived from biomass. Our proprietary collection of energy crop parent lines, known as germplasm, in combination with our pipeline of biotechnology traits allows us to develop bioenergy feedstocks to meet the needs of both biomass refineries and growers of biomass, all while using less water and less fertilizer than row crops like corn or soybean, even if grown on marginal land. We believe that the strength of our technology has been validated by the receipt of multiple competitive grants and collaborations, including a United States Agency for International Development, or USAID, grant and one of the U.S. Department of Energy’s first Advanced Research Project Agency for Energy, or ARPA-E, grants in 2009, as well as a $137 million multi-year collaboration with Monsanto Company signed in 2002. We also have significant intellectual property rights to our technology.


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Our Products
 
We recently began marketing sweet sorghum seeds in Brazil and have sold switchgrass and high biomass sorghum seeds in the United States under our brand, Blade Energy Crops, or Blade. Our largest immediate commercial opportunity is the Brazilian ethanol market, which currently uses sugarcane as its predominant feedstock. Due to the inherent limitations of sugarcane physiology and growth patterns, Brazilian mill operators, which have an estimated 3.4 million metric tons per day of crushing capacity, can only obtain usable sugarcane approximately 200 days per year. Boa Vista / Nova Fronteira, a joint venture of Grupo São Martinho S.A. and Petrobras Biofuels, recently planted, harvested and processed a commercial-scale planting of our sweet sorghum products and produced both ethanol and power using the existing agricultural equipment and processing infrastructure. Similar activities are in process with two other Brazilian ethanol producers, ADM do Brasil Ltda. and Usina Rio Pardo S.A. We believe the success of our first commercial-scale planting demonstrates the “drop-in” nature of our sweet sorghum products, and along with the seed-based propagation, shorter growing cycle and lower water and fertilizer requirements of sweet sorghum relative to sugarcane, will serve as the basis for expanded adoption of this product line as a feedstock for ethanol and power production in Brazil and other markets. We believe the adoption of our sweet sorghum hybrids could extend a mill’s operations by approximately 60 days.
 
We also work with refining technology companies in the emerging cellulosic biofuels and bio-based chemicals markets. We believe that dedicated energy crops will enable both individual renewable energy projects and the industry as a whole to reach greater scale and sustainability, at lower costs, than other potential sources of biomass. We believe our dedicated energy crop portfolio is compatible with a number of developing cellulosic biofuels conversion technologies and we are working with companies focusing on petroleum-refining technologies, such as UOP, LLC, as well as chemical companies, such as Gruppo Mossi & Ghisolfi, or Gruppo M&G, to test our energy crops in their respective production processes. We have also conducted joint trials with, or sold seed to, AGCO Corporation, EdeniQ, Inc. and Hawai’i BioEnergy, LLC, among others. We recently began a collaboration with Valero Services, Inc. to further evaluate feedstock supply strategies with dedicated energy crops.
 
Our dedicated energy crops also can be used to generate electricity in existing solid-fuel power facilities, such as coal-fired generating plants. We believe we will see a material increase in demand for biopower in the event that additional renewable energy legislation is passed in the United States, Europe or other countries that requires a higher percentage of generation from low-carbon sources or provides equal production incentives for the co-firing of biomass with coal, as are currently available for wind and solar power. We believe that our products can be used by existing growers, pellet mills and utilities, and can be cost competitive with existing biopower feedstocks, such as wood pellets.
 
Finally, due to the nature of biotechnology, we believe other crops can benefit from many of the traits we are developing for dedicated energy crops, such as traits that improve water use efficiency and salt tolerance. By combining genes into a series of stacks, we believe that we can achieve step-change improvements to the productivity of many row crops, including corn, soybean, rice and wheat. We have also generated many biotech traits specifically for cereal crops, such as rice, that increase grain yields and provide greater yield stability across different environments. We are inserting these and other traits into commercial rice varieties and plan to trial them in multiple locations in Asia this year.
 
Market Opportunity
 
The world continues to seek economic and environmentally sound alternatives to fossil fuel-based transportation fuels and power. We believe bioenergy is one of the few viable replacements for fossil fuels. Unlike other renewable technologies, biofuels are intended to utilize existing vehicles and transportation fuel infrastructure. Similarly, biopower, unlike wind and solar power, can provide baseload and dispatchable generation of renewable electricity. Despite the potential of biofuels, first-


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generation biofuel feedstocks have demonstrated their limitations in terms of scale, perceived competition with food production, net energy balance, and dependence on government subsidies. Similarly, current sources of biomass, such as forestry residues and agricultural wastes, are limited in scale and are not optimized for use in bioenergy. They are also by-products derived from other processes and therefore subject to supply disruptions. Our dedicated energy crops provide an attractive combination of high yield density, high net energy balances, low input requirements, the ability to grow on marginal land and, as a dedicated source of feedstock, the potential to be tailored for specific production and refining processes. We believe that dedicated energy crops will become a critical component for growth of the biofuel, bio-based chemicals and biopower markets.
 
Biofuels and Bio-Based Chemicals
 
Modern lifestyles and economies are highly reliant on petroleum and its by-products across a wide variety of industries, including light-duty transportation, aviation, diesel, shipping, lubricants, polymers, resins and cosmetics. According to the U.S. Energy Information Administration, or EIA, global oil production averaged 87.9 million barrels per day in the first quarter of 2011. The transportation fuel component of petroleum is valued at over $2 trillion per year, according to EIA. The vast majority of bio-based replacements for petroleum and petroleum-based chemicals are currently produced by fermentation of starch sources and free sugars primarily derived from corn and sugarcane, respectively. Commonly referred to as first-generation biofuels and bio-based chemicals, the production and conversion processes for these feedstocks are well-established. However, as the world looks to increase its consumption of biofuels and their derivatives, these first-generation feedstocks face challenges to meet increased demand.
 
In Brazil, where the country has recently been importing corn ethanol to meet its demand, we believe that mill operators will seek alternatives that will allow them to increase production utilization of their existing mills beyond the average 200 days per year schedule. On a global basis, we expect petroleum consumption will be further replaced by products made from the conversion of non-food biomass into biofuels and bio-based chemicals. Today, there are multiple companies, including large multinational companies, such as BP p.l.c., Royal Dutch Shell plc, Total S.A. and Valero Energy Corporation, and independent companies, such as KiOR, Inc. and Coskata, Inc., focused on improving non-food biomass conversion technologies. According to the International Energy Agency, or IEA, biofuel production could reach approximately 112 billion gallons per year by 2030, up from 26 billion gallons in 2010. To meet these targets, the IEA believes feedstock production would need to increase to 150 million acres in 2030, up from 75 million acres in 2010. We believe quadrupling the volume of biofuels while only doubling the feedstock production acres will require higher yielding second-generation feedstocks.
 
Biopower
 
Globally, 7.92 trillion kilowatt-hours of electricity were generated from coal in 2007, or 42% of total global power generation, according to the EIA, which we estimate required 3.6 billion tons of coal. By comparison, the EIA reports that globally, approximately 235 billion kilowatt-hours of electricity were generated from biomass and wastes, or 57% of all renewable energy generation, excluding hydropower, which we estimate required 200 million dry tons of biomass. The conversion of biomass to power has traditionally been fueled by bio-based waste products and residues from the paper and timber industries. As is the case for biofuels, we believe this practice has limited the size, location, efficiency and scale of biomass power generation because power producers can not reliably secure long-term supplies and consistent quality feedstock. We believe we will see a material increase in demand for biopower in the event that additional renewable energy legislation is passed in the United States, Europe or other countries that requires a higher percentage of generation from low-carbon sources, or that incentivizes the co-firing of biomass.


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Food and Feed Crops
 
According to the International Service for the Acquisition of Agri-Biotech Applications, or ISAAA, approximately 366 million acres of biotechnology crops were planted globally in 2010. The global market value of biotechnology crop seeds was $11.2 billion, as reported by ISAAA. In order to continue the productivity gains made in many crops over the past 75 years, and to do so in a more sustainable manner, we believe that advanced breeding methods, and biotech traits, in particular, will be required to produce higher performance crops that make more productive use of cultivated land, as well as to develop more robust, stress-tolerant crops that can grow under more difficult conditions and on marginal land.
 
Our Solutions
 
We believe that nearly all bioenergy and bio-based chemical applications will ultimately depend on high yielding, low-cost, low-carbon, scalable, reliable and sustainable sources of feedstock. We believe biomass from our dedicated energy crops and traits have the potential to become the common denominator in a broad array of bio-based products, including ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, as well as electric power and heat, and can enable the development of larger-scale processing facilities given the high yield density and conversion efficiency of dedicated energy crops. Specifically, our dedicated energy crops have the following characteristics, which we believe will make them a critical component in the large-scale production of these bio-based products:
 
“Drop-in” Products
 
Our products are “drop-in” solutions because they can be planted, harvested and processed using existing agricultural equipment with little or no modification and are being developed to be “drop-in” for all conversion technologies using sugarcane or biomass feedstocks, facilitating their rapid adoption.
 
High Yield Density
 
Our dedicated energy crops are developed to produce high biomass or sugar yields per acre. For cellulosic biofuels, bio-based chemicals and biopower, energy grasses can yield significantly more dry tons per acre per year compared to agricultural residues and woody biomass. This maximizes the productivity of available land and shortens the collection radius for a conversion facility of a particular size. As transportation costs can be a significant element in the total cost of biomass, we believe our high yield density crops will facilitate the construction of larger processing facilities because more biomass could be collected from a defined area of land around the facility. In turn, these larger facilities will benefit from economies of scale, resulting in lower production and capital cost per gallon produced.
 
Dedicated to Bioenergy
 
Unlike many other bioenergy feedstocks, our dedicated energy crops are currently not intended for other uses and are typically grown exclusively to be harvested as part of the bioenergy value chain, creating a stable supply that will appeal to owners of conversion technologies who will have invested significant capital in their infrastructure and will therefore require reliable and cost-effective feedstocks.
 
Suited to Marginal Land
 
Our dedicated energy crops can grow in a broad range of environments, including those not well-suited for most food crops. We are developing biotech traits that provide salt tolerance, drought tolerance and greater nitrogen use efficiency.


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Scalable to Meet Demand
 
Our energy crops are highly scalable, allowing us to match our production with growing demand for our seeds on relatively short notice compared to sugarcane, which can take several years to scale up commercially.
 
Competitive Strengths
 
We believe that we possess a number of competitive strengths that position us to become a leading provider of dedicated energy crop seeds and traits, including:
 
Commercial Products Available Today
 
We currently have a number of commercially available seed products, including sweet sorghum, switchgrass and high biomass sorghum. Our sweet sorghum hybrids have recently been successfully planted, harvested and processed into ethanol and power in Brazil in our first commercial-scale project. We are in active discussions with a number of Brazilian ethanol producers for use of our sweet sorghum seeds for the 2011-2012 growing season. We believe our demonstrated success in the 2010-2011 growing season will facilitate the rapid development of this market and enable the expansion of our market share in Brazil and in other geographies.
 
Attractive Business Model
 
Seed businesses traditionally incur significant research and development expenditures and have long product development time lines, but benefit from a combination of high gross margins, low capital expenditure requirements and intellectual property protection. We believe we can position our business to take advantage of low production costs relative to the high value of our products to our customers.
 
Innovative R&D Technology Platforms
 
In order to maintain the strong position we have established with our combined strengths in germplasm and field-validated traits, we use our research and development expertise to continually improve our product offerings. We believe that our innovative integrated breeding and biotechnology approach allows us to efficiently identify traits, effectively express these traits in crops, and more quickly commercialize new and improved seeds and traits for the market. We have both biotech traits and non-biotech traits and some of our biotech traits have been successfully evaluated in the field; however, they are still several years away from commercialization.
 
Extensive Proprietary Portfolios of Germplasm and Traits
 
While many companies have developed portfolios of germplasm or traits, we believe we are one of the only companies focused on dedicated energy crops with large portfolios of both germplasm and field-validated traits. We believe new market entrants would need to cultivate several generations of germplasm to achieve performance equivalent to our current product portfolio by which time we believe we will have further evolved our germplasm. Therefore, we believe our proprietary position would be difficult and time-consuming to replicate. We believe that we have established a strong intellectual property position in plant genes, traits and energy crop germplasm. As of April 30, 2011, we owned or had exclusive licensed rights to approximately 110 issued patents and approximately 200 pending patent applications in the United States and in various foreign jurisdictions.
 
Management Team with Significant Industry Experience
 
Our experienced management team possesses a deep understanding of a variety of agricultural, chemical and industrial biotechnology businesses, including the seed industry, as well as our regional markets of Brazil, the United States and Europe. Our management team also includes top scientists and industry experts, some of whom have served in leadership roles at large, multinational


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corporations, served on advisory committees for the U.S. Department of Energy, led ground-breaking research studies and published numerous scientific articles.
 
Our Strategy
 
Our objective is to be the leading provider of dedicated energy crop seeds and traits to the renewable energy industry, including first-generation biofuels such as ethanol as well as cellulosic biofuels, biopower and bio-based chemicals by employing the following strategies:
 
Expand Our Presence in Brazil
 
We intend to use our recent success with leading ethanol producers, including Boa Vista / Nova Fronteira, a joint venture of Grupo São Martinho S.A. and Petrobras Biofuels, to promote brand awareness and expand our presence in Brazil by partnering with additional ethanol mills and other industry participants to conduct field trials and larger-scale commercial plantings as well as introduce new products into the Brazilian market.
 
Expand Strategic Collaborations to Develop and Market Cellulosic Biofuels
 
We plan to play a significant role in developing the second-generation biofuels and bio-based chemicals market, which we believe represents a significant opportunity. We intend to establish new collaborations and expand our current collaborations with leading cellulosic biorefining companies, technology providers and project developers to further validate our products across various downstream technologies and to produce optimized feedstocks that are tailored to meet the specifications of existing and new refining technologies.
 
Expand Our Business into New Markets
 
We intend to market our Blade Energy Crops brand as a symbol of quality, innovation and value across multiple biofuel, bio-based chemicals and biopower markets in a broad range of climates and geographies. We intend to use our large portfolios of field-validated traits and germplasm, combined with our advanced technology platforms, to develop products for a wide variety of niches and seize upon future market opportunities, regardless of the fuel or chemical molecule (e.g., ethanol, butanol, farnesene, biogasoline, biodiesel, biocrude), biochemical (e.g., bioplastics, lubricants) or engine choice (e.g., all electric, E85, E15, diesel, hybrid, plug-in hybrid).
 
Build New Relationships and Enhance Established Collaborations in the Global Biopower Market
 
We intend to cultivate collaborations with new parties, particularly those in Europe where we believe the market opportunity for biopower is more established today and the market need is more immediate in light of existing government regulations. We will work with utility companies and independent power producers to drive demand for our dedicated energy crops in the biopower market.
 
Continue Innovation and New Product Development
 
We are continuing to develop innovative solutions using a broad range of technological tools, including genomics, biotechnology and proprietary bioinformatics in order to produce crop varieties with improved yields and other performance characteristics. For example, we have identified traits that will help optimize results for growers located in geographies with varying day lengths, rainfall, temperatures and soil composition (e.g., salt, aluminum and nitrogen).
 
Continue to Build Our Intellectual Property Portfolio
 
We believe we have established a strong intellectual property position in plant genes, traits and energy crop germplasm. We believe we are one of the few companies focused on dedicated energy


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crops that have this combination of intellectual property assets. We use our integrated technology platforms to continually improve our products and develop innovations that will further strengthen our intellectual property position.
 
Summary of Risk Factors
 
Our business is subject to a number of risks and uncertainties that you should understand before making an investment decision. These risks are discussed more fully in the section entitled “Risk Factors” following this prospectus summary. These risks include, but are not limited to, the following:
 
  •  We have a history of net losses; we expect to continue to incur net losses and we may not achieve or maintain profitability.
 
  •  Our products are in the early stages of commercialization.
 
  •  The markets for some of our dedicated energy crops are not well established and may take years to develop or may never develop and our growth depends on customer adoption of our dedicated energy crops.
 
  •  Our crops are new and most growers will require substantial instruction to successfully establish, grow and harvest crops grown from our seeds.
 
  •  Our largest immediate commercial opportunity is the Brazilian ethanol market and we only recently completed our first commercial-scale plantings of our sweet sorghum products in Brazil.
 
  •  We have not yet established pricing for our products, including our sweet sorghum products, for the Brazilian market.
 
  •  Our business will be adversely affected if the field trials being conducted by our collaborators or potential customers fail to perform as expected.
 
  •  Our inability to adequately protect our proprietary technologies and products could harm our competitive position.
 
  •  Litigation or other proceedings or third party claims of infringement could require us to spend time and money and could severely disrupt our business.
 
Corporate Information
 
We were incorporated in the State of Delaware in March 1996 under the name Ceres, Inc. Our corporate headquarters are located at 1535 Rancho Conejo Boulevard, Thousand Oaks, California 91320, and our telephone number is +1(805) 376-6500. Our website address is www.ceres.net. The information contained on our website or that can be accessed through our website is not part of this prospectus, and investors should not rely on any such information in deciding whether to purchase our common stock.
 
Our logos, “Ceres®”, “The Energy Crop Company®”, “Blade Energy Crops®”, “Blade®” and “Skyscraper®” and other trademarks or service marks of Ceres, Inc. appearing in this prospectus are the property of Ceres, Inc. This prospectus contains additional trade names, trademarks and service marks of other companies. We do not intend our use or display of other companies’ trade names, trademarks or service marks to imply relationships with, or endorsement or sponsorship of us by, these other companies.


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THE OFFERING
 
Common stock offered            shares.
 
Common stock to be outstanding after this offering            shares, or          shares if the underwriters exercise their option to purchase additional shares in full.
 
Use of proceeds We intend to use the net proceeds from this offering for seed production and commercialization expenses, research and development, capital expenditures, working capital and other general corporate purposes, which may include acquisitions of other companies, assets or technologies. See “Use of Proceeds”.
 
Proposed Nasdaq Global Market trading symbol “CERE”
 
 
 
 
The number of shares of common stock that will be outstanding after this offering is based on shares outstanding as of February 28, 2011, and excludes:
 
  •  7,192,391 shares of common stock issuable upon exercise of options to purchase our common stock outstanding as of February 28, 2011, at a weighted average exercise price of $1.62 per share;
 
  •  600,000 shares of common stock issuable upon exercise of warrants to purchase our common stock outstanding as of February 28, 2011, at a weighted average exercise price of $10.00 per share that do not expire on the completion of this offering;
 
  •  61,537 shares of common stock issuable upon exercise of warrants to purchase our preferred stock outstanding as of February 28, 2011, at a weighted average exercise price of $6.50 per share that do not expire on the completion of this offering; these preferred stock warrants will automatically convert to common stock warrants upon the completion of this offering;
 
  •  744,454 shares of common stock reserved as of February 28, 2011, for future issuance under our 2010 Stock Option/Stock Issuance Plan; and
 
  •            shares of common stock reserved for future issuance under our 2011 Equity Incentive Plan, which will become effective on the day prior to the day upon which we become subject to the reporting requirements of the Securities Exchange Act of 1934, as amended, or the Exchange Act.
 
Except as otherwise indicated, all information in this prospectus assumes:
 
  •  the automatic conversion of all outstanding shares of our convertible preferred stock into an aggregate of 46,059,819 shares of common stock effective immediately prior to the completion of this offering;
 
  •  the issuance of           shares of common stock immediately prior to the completion of this offering upon the net exercise of warrants outstanding to purchase shares of common stock issued to investors holding our Series F Convertible Preferred Stock, or the Series F Warrants, and our Series G Convertible Preferred Stock, or the Series G Warrants, which would otherwise expire upon the completion of this offering, based upon an assumed initial public offering price of $      per share, the midpoint of the range set forth on the cover of this prospectus;
 
  •  the filing of our amended and restated certificate of incorporation immediately prior to the completion of this offering; and
 
  •  no exercise by the underwriters of their right to purchase up to an additional          shares of common stock at the initial public offering price.


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SUMMARY CONSOLIDATED FINANCIAL DATA
 
The following table summarizes our consolidated financial data. In 2009, we changed our fiscal year end from December 31 to August 31. The change was effective for the eight-month period ended August 31, 2009. We have derived the following summary consolidated statement of operations data for the fiscal years ended December 31, 2007 and 2008, the eight months ended August 31, 2009, and the fiscal year ended August 31, 2010, from our audited consolidated financial statements appearing elsewhere in this prospectus. The summary consolidated financial data for the six-month periods ended February 28, 2010 and 2011 have been derived from our unaudited consolidated financial statements included elsewhere in this prospectus. The unaudited consolidated financial statements have been prepared on a basis consistent with our audited consolidated financial statements and include, in the opinion of management, all adjustments, consisting only of normal and recurring adjustments, necessary for a fair presentation of such consolidated financial data. Results for interim periods are not necessarily indicative of results for a full fiscal year. Historical results are not necessarily indicative of results for future periods. You should read the summary of our consolidated financial data set forth below together with the more detailed information contained in “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and our consolidated financial statements and the related notes appearing elsewhere in this prospectus.
 
                                                 
          Eight
             
          Months
          Six Months
 
          Ended
    Year Ended
    Ended
 
    Year Ended December 31,     August 31,     August 31,     February 28,  
   
2007
   
2008
   
2009
   
2010
   
2010
   
2011
 
                            (Unaudited)  
    (In thousands, except share and per share data)  
 
Consolidated Statement of Operations
                                               
Revenues
                                               
Product sales
  $     $ 64     $ 98     $ 288     $ 5     $ 9  
Collaborative research and government grants
    7,180       3,880       2,328       6,326       2,497       3,320  
                                                 
Total revenue
    7,180       3,944       2,426       6,614       2,502       3,329  
                                                 
Cost and operating expenses
                                               
Cost of product sales
          3,777       2,690       2,946       1,424       1,330  
Research and development
    19,220       20,309       12,397       16,697       8,516       8,641  
Selling, general and administrative
    9,811       8,784       6,645       9,207       4,237       4,339  
                                                 
Total cost and operating expenses
    29,031       32,870       21,732       28,850       14,177       14,310  
                                                 
Loss from operations
    (21,851 )     (28,926 )     (19,306 )     (22,236 )     (11,675 )     (10,981 )
                                                 
Interest expense
    (123 )           (5 )     (153 )     (3 )     (248 )
Interest income
    1,521       2,001       243       23       20       34  
Other income (expense)
    5             161       (152 )     (64 )     (85 )
                                                 
Loss before income taxes
    (20,448 )     (26,925 )     (18,907 )     (22,518 )     (11,722 )     (11,280 )
Income tax benefit (expense)
    (7 )     148       211       (65 )     (1 )     (1 )
                                                 
Net loss
  $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
                                                 
Basic and diluted net loss per share attributable to common stockholders(1)
  $ (3.84 )   $ (4.89 )   $ (3.33 )   $ (3.90 )   $ (2.04 )   $ (1.91 )
Weighted average outstanding common shares used for net loss per share attributable to common stockholders:
                                               
Basic and diluted(1)
    5,323,259       5,473,090       5,621,671       5,791,443       5,751,539       5,900,947  
Pro forma net loss per share:
                                               
Basic and diluted (unaudited)(2)
                          $ (0.46 )           $ (0.22 )
                                                 
Weighted average outstanding common shares used in computing pro forma net loss per share:
                                               
Basic and diluted (unaudited)(2)
                            49,339,144               51,960,766  
                                                 


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(1) The basic and diluted loss per share are computed by dividing the net loss attributable to common stockholders by the weighted average number of common shares outstanding during the period. For the periods where we presented losses, all potentially dilutive common shares comprising of stock options, warrants and convertible preferred stock are anti-dilutive.
 
(2) The unaudited pro forma basic and diluted loss per common share have been computed as though the conversion had occurred as of September 1, 2009 to give effect to: (i) the automatic conversion of all outstanding shares of our convertible preferred stock into an aggregate of 46,059,819 shares of common stock immediately prior to the completion of this offering using the if-converted method and (ii) the issuance of           shares of common stock immediately prior to the completion of this offering upon the net exercise of the Series F Warrants and Series G Warrants, which would otherwise expire upon the completion of this offering, based upon an assumed initial public offering price of $           per share, the midpoint of the range set forth on the cover of this prospectus using the treasury stock method.
 
Our consolidated balance sheet data as of February 28, 2011 is presented:
 
  •  on an actual basis;
 
  •  on a pro forma basis to give effect to (i) the conversion of all outstanding shares of our convertible preferred stock into 46,059,819 shares of our common stock and (ii) the issuance of           shares of our common stock upon the assumed net exercise of the Series F Warrants and Series G Warrants that would otherwise expire on the completion of this offering, based on an assumed initial public offering price of $      per share, the midpoint of the range set forth on the cover of this prospectus; and
 
  •  on a pro forma as adjusted basis to give effect to the pro forma adjustments and the sale of           shares of common stock by us in this offering at an assumed public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus, and after deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us.
 
                         
    As of February 28, 2011
            Pro Forma as
   
Actual
 
Pro Forma
 
Adjusted(1)
    (In thousands)
    (Unaudited)
 
Consolidated Balance Sheet Data:
                       
Cash and cash equivalents
  $ 22,489     $ 22,489     $          
Total assets
    35,213       35,213          
Total indebtedness (including short-term indebtedness)
    5,287       5,287          
Common and preferred stock warrant liabilities
    8,997                
Convertible preferred stock
    197,502                
Total stockholders’ (deficit) equity
    (181,480 )     25,019          
 
(1) Each $1.00 increase or decrease in the assumed public offering price of $      per share, the midpoint of the range reflected on the cover of this prospectus, would increase or decrease, as applicable, our cash and cash equivalents, total assets and total stockholders’ equity (deficit) by approximately $      million, assuming that the number of shares offered by us, as set forth on the cover of this prospectus, remains the same and after deducting the estimated underwriting discounts and commissions and estimated offering expenses payable by us.


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RISK FACTORS
 
Investing in our common stock involves a high degree of risk. You should carefully consider the risks and uncertainties described below, together with all of the other information in this prospectus, including the consolidated financial statements and the related notes appearing elsewhere in this prospectus, before making an investment decision. If any of the following risks actually occurs, our business, financial condition, results of operations and future prospects could be materially and adversely affected. The trading price of our common stock could decline due to any of these risks, and, as a result, you may lose all or part of your investment in our common stock.
 
Risks Related to Our Business
 
We have a history of net losses; we expect to continue to incur net losses and we may not achieve or maintain profitability.
 
With the exception of the fiscal years ended December 31, 2003, 2005 and 2006, we have incurred net losses each fiscal year since our inception, as well as for the six months ended February 28, 2011. From our inception to February 28, 2011, we had an accumulated deficit of $187.6 million. We expect to incur additional losses for at least the next several years as we continue to invest in our research and development programs, to develop new products and to move forward with our commercialization activities. The extent of our future net losses will depend, in part, on our product sales growth and revenue from collaborations and government grants, and on the level of our operating expenses. To date, substantially all of our revenue has been derived from collaboration agreements and government grants, and we have had very limited revenue from seed sales. Over the next several years, we expect our revenue will shift from being derived primarily from collaborations and government grants to product sales. Our ability to generate future revenue will depend upon our ability to meet our obligations under our collaborations and government grants, to enter into new collaborations or out-licensing agreements and to successfully commercialize our products. The market for seeds for dedicated energy crops is relatively new and still developing and our success in generating revenue from product sales depends in the near term in large part on the success of our sweet sorghum products in Brazil and in the future on the adoption of other dedicated energy crops as a biomass feedstock. Even if we do achieve profitability, we may not be able to sustain or increase our profitability on a quarterly or annual basis.
 
Our products are in the early stages of commercialization.
 
Our existing products are in the early stages of commercialization and our efforts to commercialize our products may not be successful. Our product sales for the year ended August 31, 2010 and the six months ended February 28, 2011 were minimal and were derived mainly from sales to third parties that were field testing our products. Before we can make commercial sales of our sweet sorghum seeds in Brazil, we need to obtain necessary governmental registrations, which we expect to receive in the fourth calendar quarter of 2011; however, we may not be able to obtain such registrations in our expected time frame, if at all. To date, we have not sold any sweet sorghum seeds in the Brazilian market. Although we are in discussions with various sugarcane-to-ethanol mill owners in Brazil for the purchase of our sweet sorghum products as a “drop-in” feedstock, we do not know whether they will purchase our sweet sorghum seeds for the 2011-2012 growing season, or if they do, how much they will purchase or at what price.
 
The markets for our other products, mainly switchgrass and high biomass sorghum, are not fully developed. We completed our first sale of switchgrass seeds in 2009 and high biomass sorghum seeds in 2010 and to date have sold less than $0.5 million of these products in the aggregate. In addition, our seed-propagated miscanthus product is still under development and is not yet available for commercial sale. Our business strategy going forward heavily relies on our ability to introduce


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crops with genetically engineered, or biotech traits. By contrast, our existing sweet sorghum, switchgrass and high biomass sorghum products have all been created through the use of conventional breeding. As a result, even if these products are successfully sold and adopted by customers, they do not necessarily demonstrate our ability to successfully develop, market and sell biotechnology products. If we are not able to bring our existing products or new products with significant commercial potential to market in a timely manner, we will not be successful in building a sustainable or profitable business.
 
The markets for some of our dedicated energy crops are not well established and may take years to develop or may never develop and our growth depends on customer adoption of our dedicated energy crops.
 
We sell proprietary seeds to produce dedicated energy crops for the renewable energy market, which is not well established and is evolving. Although our sweet sorghum products are targeted for use as a feedstock to produce ethanol, ethanol has historically been produced from corn in the United States and sugarcane in Brazil and we will need to demonstrate on a commercial scale that sweet sorghum can reliably be used as a cost-efficient feedstock for ethanol production. Cellulosic biofuels have been produced on a limited scale from woody biomass, such as wood chips, or agricultural residues, and we will need to demonstrate on a commercial scale that biomass grown from our seed products, including switchgrass and high biomass sorghum, can be used as cost-efficient feedstocks for the production of biofuels, biopower and other bio-based products.
 
Currently the market for dedicated energy crops is not well established, primarily because of the lack of infrastructure to support the development of this market, including the lack of commercial-scale production facilities capable of converting cellulosic feedstocks, referred to as cellulosic biorefineries. Existing first-generation ethanol biorefineries are not capable of using cellulosic feedstocks to produce ethanol. The development of this industry is also dependent, in large part, upon the efforts of many companies to improve conversion technologies which will play a significant role in enabling more cost-effective means of converting biomass into energy. A delay in the construction of cellulosic biorefineries or a failure to meaningfully improve conversion technologies could curtail one of our most significant market opportunities. Even if cellulosic biorefineries are established in the future, they may elect to use agricultural residues, waste material or woody biomass as feedstocks rather than dedicated energy crops, resulting in the lack of a robust market for our products.
 
Traditionally the market for biopower, which is the generation of electric power from combusting biomass, has been fueled mainly by bio-based waste products from the paper and timber industries. We believe that expansion of this market will be driven by governmental policies such as additional state and new federal mandates that require a certain percentage or absolute amount of electricity be generated from renewable sources by specified dates or production tax credits for co-firing biomass. We cannot predict the effect that existing legislation or the lack of legislation will have on the development of the biopower market in the United States or the European Union. To the extent that the market does not develop or biopower producers elect to continue to rely on bio-based waste products from the paper and timber industries, rather than dedicated energy crops, our market opportunity will be limited.
 
Our crops are new and most growers will require substantial instruction to successfully establish, grow and harvest crops grown from our seeds.
 
As part of our product development activities and customer support, we provide agricultural producers and biomass procurers with information and protocols regarding the establishment, management, harvest, transportation and storage of our energy crops for use in bioenergy. In addition to seed selections, such crop management recommendations may include equipment selection, planting and harvest timing, application of crop protection chemicals or herbicides and storage systems. While some of our crops, such as sorghum and switchgrass, have been grown for other uses, the crop


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management practices required for energy crop production are still new and are still evolving. Our general or specific protocols may not apply to all circumstances, may not be sufficient, or may be incorrect, leading to reduced yields, crop failures or other production problems or losses by our customers or collaborators. Such failures may harm our customer or collaborator relationships, our reputation and our ability to successfully market our products, and may lead to liability claims against us. Further, the use of our seeds may require a change in current planting, rotation or agronomic practices.
 
Our largest immediate commercial opportunity is the Brazilian ethanol market and we only recently completed our first commercial-scale plantings of our sweet sorghum products in Brazil.
 
We recently concluded our first commercial-scale plantings of sweet sorghum in Brazil. While we have received initial results from these plantings that indicate the plantings were successful, we do not have a complete analysis of the yield per variety, the fermentable sugar produced for each variety, any processing issues or ethanol or electricity yields. To the extent that these results do not meet our or our collaborators’ expectations, we may experience a significant delay in commercializing our sweet sorghum products in Brazil. We are working with a number of other mill owners in Brazil that are testing our sweet sorghum products, but those plantings have not yet been harvested and may not meet performance expectations. Certain of these plantings deliberately occurred on marginal land and the harvest has been delayed beyond the ideal time in order to stress test the results and determine the level to which adverse conditions will affect the yield and other performance characteristics of our products. We expect the results of these trials will therefore be less than optimal and could create the perception that the planting was a failure. This could in turn discourage other mill owners from trying our sweet sorghum products. The future success of our “drop-in” sweet sorghum products in Brazil will depend on mill owners’ ability or willingness to devote proper resources, including land, to our products and the timing of planting and harvesting of our sweet sorghum products. The decision to devote land and resources to a particular crop is dependent on many factors, some of which are outside of our control. To the extent that our sweet sorghum field trials do not result in expected yields or are not replicable on a larger scale, we may have difficulty convincing sugarcane-to-ethanol mill owners to field test our products or purchase our sweet sorghum products.
 
We have not yet established pricing for our products, including our sweet sorghum products, for the Brazilian market.
 
Our products are in the early stages of commercialization and there is no established market for them. We intend to base the pricing of our products on our assessment of the value that our products provide to the customer, rather than on the cost of production. We may include trait fees in our seed prices, but our potential customers may be unwilling to pay such fees. If our customers attribute a lower value to our products than we do, they may not be willing to pay the premium prices we expect to charge. Pricing levels may also be negatively affected if our products are unsuccessful in producing the yields we expect. In addition, if our competitors are able to develop competitive products and offer them at lower prices, we may be forced to lower our prices.
 
We have not established pricing for our sweet sorghum products in the Brazilian market. Although we are in active discussions with several mill owners in Brazil, we have not entered into a purchase order with any potential customer. To date, we have not charged for our sweet sorghum seeds used in our commercial-scale plantings in Brazil as our products were being field tested by the mills. Because we have not sold any of our sweet sorghum seeds in Brazil and there is no established market price for sweet sorghum, we will need to negotiate initial pricing with our potential customers. The customers we intend to target in Brazil are generally large mill owners with long operating histories in the sugarcane-to-ethanol market that will have significant leverage in negotiating commercial relationships with us. As a result, we do not know whether these pricing negotiations will result in


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adequate margins or accurately reflect our pricing strategies, which could have a material adverse effect on our results of operations.
 
Our business will be adversely affected if the field trials being conducted by our collaborators or potential customers fail to perform as expected.
 
We and our collaborators and potential customers are currently conducting field trials of our products in various geographies around the world. We have limited control over field trials that are conducted by third parties and are dependent on their ability to follow our suggested protocols. For example, if our seeds are planted too late in the growing season or are over or under-fertilized, the field trial may not perform as expected. If a field trial does not perform as expected or does not result in continued large-scale trials, the introduction of our products may be delayed or abandoned and our product sales revenue and profitability could be materially adversely affected.
 
Environmental factors, including weather, moisture, and plant infestations, may negatively affect the crops grown from our seeds or our seed inventories.
 
The plants grown from our seeds are subject to the vagaries of the weather and the environment, either of which can reduce crop yields. Weather conditions and natural disasters, such as heavy rains, hurricanes, hail, floods, tornados, freezing conditions, drought, fire or other natural disasters, can affect the timing of planting or harvesting and the acreage planted, as well as yields. The effects of disease, pests, fungi, bacteria and insect infestations can also be unpredictable and devastating to crops, potentially rendering all or a substantial portion of the affected harvests unsuitable for use. In addition, our crops and harvests may be adversely affected by climate change resulting from global warming, including changes in precipitation patterns and the increased frequency of extreme weather events. Each of these weather and environmental factors affects geographic regions differently. Should these or other environmental factors adversely affect the crops grown from our products, growers may be unable or unwilling to purchase our seeds or they may choose to purchase other seeds deemed better adapted to the particular climatic or environmental conditions they are facing.
 
The quality of our seed inventory could deteriorate due to a variety of factors, including the passage of time, temperature variations, moisture, insects, fungi, bacteria, disease or pests. If the quality of our seed inventory were to deteriorate below an acceptable level, the value of our seed inventory would decrease significantly and we might not be able to meet product demand. Should a substantial portion of our seed inventory be damaged by moisture, insects, fungi, bacteria, disease or pests, our business and financial condition could be materially and adversely harmed.
 
Our seed business is highly seasonal and subject to weather conditions and other factors beyond our control, which may cause our sales and operating results to fluctuate significantly.
 
The sale of seeds is dependent upon planting and growing seasons, which vary from year to year, and are expected to result in both highly seasonal patterns and substantial fluctuations in quarterly sales and profitability. Our product sales for the year ended August 31, 2010 and the six months ended February 28, 2011 were minimal and, accordingly, we have not yet experienced the full nature or extent to which our business may be seasonal. We expect that sales of our seeds in Brazil will typically be higher in our first and fourth fiscal quarters, due to the timing of the planting decisions made by our customers. As we increase our sales in our current markets, and as we expand into new markets in different geographies, it is possible that we may experience different seasonality patterns in our business. Weather conditions and natural disasters, such as heavy rains, hurricanes, hail, floods, tornadoes, freezing conditions, drought or fire, also affect decisions by our customers about the types and amounts of seeds to plant and the timing of harvesting and planting such seeds. Disruptions that cause delays by our customers in harvesting or planting can result in the movement of orders to a future quarter, which would negatively affect the quarter and cause fluctuations in our operating results.


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A decline in the price of petroleum-based products may reduce the demand for many of our products and adversely affect our business.
 
We believe that some of the projected demand for renewable alternatives to fossil fuels is a result of the recent increase and volatility of oil prices that has occurred over the past few years. Oil and petroleum prices are currently at historically high levels. We anticipate that most of our product sales will be driven by the demand for alternatives to petroleum-based products. If the price of oil falls, and periods of lower oil prices are sustained, demand for biofuels or other bio-based products could also decline. Declining oil prices, or forecasts of a future decline in oil prices, may adversely affect the prices for renewable energy products and the prices we can obtain from our potential customers or cause potential customers to not buy our products, which could materially and adversely affect our operating results. We believe that our market opportunity to sell sweet sorghum seeds in Brazil is based, at least in part, on the recent shortages Brazil has encountered in producing sufficient quantities of sugarcane-based ethanol to satisfy local demand. We cannot predict whether these shortages will be sustained or whether the Brazilian market will experience periods of ethanol shortages in the future.
 
A significant increase in the price of sugar relative to the price of ethanol may reduce demand for our sweet sorghum and may otherwise adversely affect our business.
 
We intend to market our sweet sorghum varieties in Brazil as a “drop-in” feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills, the operating days of which are currently limited due to the inherent limitations of sugarcane physiology and growth patterns. For example, our proprietary varieties of sweet sorghum can be harvested from February to May while sugarcane, which is grown year-round, is typically harvested from April to December, depending on weather and market conditions. In addition, we may market our sweet sorghum seeds for planting on marginal land which would not otherwise be well suited for sugarcane. However, if the price of sugar, which is produced from sugarcane and which cannot be produced from sweet sorghum today, rises significantly relative to the price of ethanol, it may become more profitable for ethanol mill operators to grow sugarcane even in adverse conditions, such as through the expansion of sugarcane fields to marginal land or the extension of the sugarcane harvesting season. During sustained periods of significantly higher sugar prices, demand for our seeds may decrease, which could materially and adversely affect our operating results.
 
Our failure to accurately forecast demand for our seeds could result in an unexpected shortfall or surplus that could negatively affect our results of operations or our brand.
 
Because of the length of time it takes to produce commercial quantities of seeds, we must make seed production decisions well in advance of product bookings. For example, we must determine our expected demand for our sweet sorghum varieties approximately six months in advance of delivery, on average, while growers or mill operators make seed purchase decisions sometimes as late as 30 days in advance of planting. Our ability to accurately forecast demand can be adversely affected by a number of factors outside of our control, including changes in market conditions, environmental factors, such as pests and diseases, and adverse weather conditions. A shortfall in the supply of our products may reduce product sales revenue, damage our reputation in the market and adversely affect customer relationships. Any surplus in the amount of seed we have on hand, may negatively impact cash flows, reduce the quality of our inventory and ultimately result in write-offs of inventory. For example, in 2009, we produced an excess of switchgrass seeds because market demand for this product developed more slowly than anticipated. Any failure on our part to produce sufficient inventory or overproduction of a particular product could harm our business, results of operations and financial condition. Additionally, our customers may generally cancel an order or request a decrease in quantity at any time prior to delivery of the seed, which may lead to a surplus of our products. Even after delivery, a customer may occasionally return our seeds.


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The performance of our sweet sorghum products in Brazil may be adversely affected by delays to the start of the Brazilian ethanol production season.
 
Once a mill owner begins to crush sugarcane or other feedstock in its mill, it generally seeks a continuous supply of the feedstock to run its mill without interruption until the feedstock is depleted. Our sweet sorghum is intended to be used as a season-extending crop. Should the sugarcane harvest season be delayed due to weather or other factors, a mill may choose to delay the harvest of sweet sorghum to avoid the downtime caused by a supply gap between a season-extending crop like sweet sorghum and sugarcane. Since our sweet sorghum grows quickly and maintains its peak sugars for one to two weeks, depending on growing conditions, delays in harvesting beyond this time period may result in lower sugar volumes per acre as well as other potential production issues as mature plants begin to decline and may lodge. Such issues could impact growers’ perception of the quality or usefulness of our products and, as a result, their willingness to purchase these products from us in the future.
 
Our product development efforts use complex integrated technology platforms and require substantial time and resources to develop and our efforts may not be successful or the rate of product improvement may be slower than expected.
 
The development of successful agricultural products using complex technology discovery platforms such as ours requires significant levels of investment in research and development, including field testing, to demonstrate their effectiveness and can take several years or more. For the fiscal year ended December 31, 2008, the eight months ended August 31, 2009, the fiscal year ended August 31, 2010 and the six months ended February 28, 2011, we spent $20.3 million, $12.4 million, $16.7 million and $8.6 million, respectively, on research and development. We intend to continue to spend significant amounts on research and development in the future to continue to improve the performance of our products. Our substantial investment in research and development may not result in significant product revenues, particularly over the next several years. To date, companies have developed and commercialized relatively few dedicated energy crops, and no genetically engineered dedicated energy crops.
 
Development of new or improved agricultural products involves risks of failure inherent in the development of products based on innovative and complex technologies. These risks include the possibility that:
 
  •  our products will fail to perform as expected in the field;
 
  •  our products will not receive necessary regulatory permits and governmental clearances in the markets in which we intend to sell them;
 
  •  our products will be viewed as too expensive by our potential customers compared to competitive products;
 
  •  our products will be difficult to produce on a large scale or will not be economical to grow;
 
  •  proprietary rights of third parties will prevent us, our collaborators, or our licensees from marketing our products; and
 
  •  third parties may develop superior or equivalent products.
 
Loss of or damage to our germplasm collection would significantly slow our product development efforts.
 
We have access to a comprehensive collection of germplasm for sweet sorghum, high biomass sorghum, switchgrass and miscanthus through strategic collaborations with leading institutions. Germplasm comprises collections of genetic resources covering the diversity of a crop, the attributes of which are inherited from generation to generation. Germplasm is a key strategic asset since it forms the basis of plant breeding programs. To the extent that we lose access to these germplasm


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collections because of the termination or breach of our collaboration agreements, our product development capabilities would be severely limited. In addition, loss of or damage to these germplasm collections would significantly impair our research and development activities. Although we restrict access to our germplasm at our research facilities to protect this valuable resource, we cannot guarantee that our efforts to protect our germplasm collection will be successful. The destruction or theft of a significant portion of our germplasm collection would adversely affect our business and results of operations.
 
The successful commercialization of our products depends on our ability to produce high-quality seeds cost-effectively on a large scale.
 
The production of commercial-scale quantities of seeds requires the multiplication of the seeds through a succession of plantings and seed harvests, and if the product is a hybrid, it must be produced from parental lines, which are mated under controlled conditions. The cost-effective production of high-quality high-volume quantities of some of our products depends on our ability to scale our production processes to produce seeds in sufficient quantity to meet demand. We cannot assure you that our existing or future seed production techniques will enable us to meet our large-scale production goals cost-effectively for the products in our pipeline. Even if we are successful in developing ways to increase seed yields and enhance seed quality, we may not be able to do so cost-effectively or on a timely basis, which could adversely affect our ability to achieve profitability. If we are unable to maintain or enhance the quality of our seeds as we increase our production capacity, including through the expected use of third parties, we may experience reductions in customer demand, higher costs and increased inventory write-offs.
 
We depend, in part, on third parties to produce our seeds.
 
We produce commercial seed either on leased land managed by us or with contract seed producers. Our current production sites are located in the United States and Puerto Rico as well as Argentina, Bolivia and Brazil. In order to meet increased demand for our seeds, we will need to enter into additional land leases or arrangements with contract seed producers. If we need to engage contract seed producers, we may not be able to identify suitable producers in a specific region and if we do, we do not know whether they will have available capacity when we need their production services, that they will be willing to dedicate a portion of their production capacity to our products or that we will be able to enter into an agreement with them on acceptable terms. If any contract seed producer that we engage fails to perform its obligations as expected or breaches or terminates their agreements with us, or if we are unable to secure the services of such third parties when and as needed, we may lose opportunities to generate revenue from product sales.
 
We are at the beginning stages of developing our Blade brand and we have limited experience in marketing and selling our products and will need to expand our sales and marketing infrastructure.
 
We are in the beginning phases of building brand awareness for our dedicated energy crops. To date, we have had very little experience selling our products. We currently have limited resources to market and sell our products on a commercial-scale across various geographic regions. As of April 30, 2011, our sales and marketing and business development departments together had seven full-time employees. Developing our sales and marketing infrastructure and gaining the necessary expertise will require that we hire additional sales and marketing personnel, which could take longer than we expect and may require significant resources. We may be unable to grow our sales and marketing or business development infrastructure to adequately cover the geographic regions where we see the most opportunity, which could slow the adoption of our products and the growth of product revenue.


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We face significant competition in all areas of our business, and if we do not compete effectively, our business will be harmed.
 
The renewable energy industry is rapidly evolving and new competitors with competing technologies are regularly entering the market. We believe the primary competitive factors in the energy crop seed industry are yield, performance, scale, price, reliable supply and sustainability. We expect to face competitors on multiple fronts. First, we expect to compete with other providers of seed and vegetative propagation materials in the market for sweet sorghum, high biomass sorghum, switchgrass and miscanthus. While the competitive landscape in these crops is limited at this time, we anticipate that as our products gain market acceptance, other competitors will be attracted to this opportunity and produce their own seed varieties. Second, we believe that new as yet unannounced crops will be introduced into the renewable energy market and that existing energy crops will attempt to gain even greater market share. Existing crops, such as corn, sugarcane and oil palm trees, currently dominate the biofuels market. As new products enter the market, our products may become obsolete or our competitors’ products may be more effective, or more effectively marketed and sold, than our products. Changes in technology and customer preferences may result in short product life cycles. To remain competitive, we will need to develop new products and enhance and improve our existing products in a timely manner. Our failure to maintain our competitive position could have a material adverse effect on our business and results of operations.
 
Our principal competitors may include major international agrochemical and agricultural biotechnology corporations, such as Advanta India Limited, The Dow Chemical Company, Monsanto Company, Pioneer Hi Bred (DuPont), KWS and Syngenta, all of which have substantially greater resources to dedicate to research and development, production, and marketing than we have. We also face direct competition from other seed companies and biotechnology companies, and from academic and government research institutions. New competitors may emerge, including through consolidation within the seed or renewable energy industry. We are unable to predict what effect evolution of the industry may have on price, selling strategies, intellectual property or our competitive position.
 
In the broader market for renewable energy, we expect to face competition from other potential feedstocks, such as biomass residues from food crops, forestry trimmings and municipal waste materials, other renewable alternatives, such as algae, solar and wind-generated electricity, and other energy crops. There are multiple technologies that process biomass into biofuels and we have yet to determine compatibility of our feedstocks with all of these processes. Our failure to develop new or enhanced products that are compatible with these alternative technologies, or a lack of market acceptance of our products as the common denominator in a broad array of bio-based products that are alternatives to petroleum based products, could have an adverse effect on our business. Significant developments in alternative technologies, such as the inexpensive and large-scale storage of solar or wind-generated energy, may materially and adversely affect our business in ways that we do not currently anticipate.
 
A significant portion of our revenue to date is generated from our collaboration agreements and we must meet our obligations under these agreements in order to be entitled to the revenue streams from these agreements.
 
Historically, a significant portion of our revenue has been generated from payments to us under collaborative research agreements with third parties and we continue to opportunistically pursue new strategic collaborations. We are obligated under these agreements to perform research activities over a particular period of time. Certain of our agreements entitle us to milestone payments in the event the specified milestone is met. If we fail to perform our obligations under these agreements or any new collaborative research agreements we may enter into in the future, our revenues may decrease, or our collaborative partners may terminate or fail to renew the agreements. In addition, any of our collaborators may fail to perform their obligations as expected, which may hinder our research and development efforts. We and our collaborators may disagree as to which party had rights to


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intellectual property developed under the agreements. Disagreements with our collaborators could develop and any conflict with a collaborator may negatively affect our relationship with one or more existing collaborators or our ability to enter into future collaboration agreements.
 
Our results of operations will be affected by the level of royalty payments that we are required to pay to third parties.
 
We are a party to license agreements with third party collaborators, including The Texas A&M University System and The Samuel Roberts Noble Foundation, that require us to remit royalty payments to these third parties if we incorporate their licensed intellectual property into our products. While we are currently working on developing numerous products that incorporate aspects of this intellectual property, we have to date only sold small amounts of such products. The amount of royalties that we could owe under these license agreements is a function of our sales and the applicable royalty rates depend on a number of factors, including the portion of our third-party collaborator’s intellectual property that is present in our products.
 
Because of our historically limited volume of sales, we have little experience in calculating royalties under these license agreements and it is unclear exactly how much of this licensed intellectual property will be included in any final products we offer for commercial sale. As a result we cannot precisely predict the amount, if any, of royalties we will owe in the future. If, once we commence sales of these products, we determine that the products include more intellectual property of our third party collaborators than we had previously determined, or if our calculations of royalty payments are incorrect, we may owe more royalties, which could negatively affect our results of operations. As our product sales increase, we may, from time-to-time, disagree with our third party collaborators as to the appropriate royalty rate and the resolution of such disputes may be costly and may consume management’s time. Furthermore, we may enter into additional license agreements in the future, which may also include royalty payments.
 
We are also a party to license agreements pursuant to which we have received licenses on certain intellectual property related to biotechnology products. When we commence sales of our biotechnology products in the future, or grant licenses to third parties to commercialize such products, we will be required to remit royalty payments to the parties from whom we have licensed intellectual property that covers such products.
 
A significant portion of our revenue to date is generated from government grants and continued availability of government grant funding is uncertain and contingent on compliance with the requirements of the grant.
 
Historically, a significant portion of our revenue has been generated from payments to us from government entities in the form of government grants whereby we are reimbursed for certain expenses incurred in connection with our research and development activities, subject to our compliance with the specific requirements of the applicable grant, including rigorous documentation requirements. To the extent that we do not comply with these requirements, our expenses incurred may not be reimbursed. Any of our existing grants or new grants that we may obtain in the future may be terminated or modified.
 
Our ability to obtain grants or incentives from government entities in the future is subject to the availability of funds under applicable government programs and approval of our applications to participate in such programs. The application process for these grants and other incentives is highly competitive. We may not be successful in obtaining any additional grants, loans or other incentives. The recent political focus on reducing spending at the U.S. federal and state levels may reduce the scope and amount of funds dedicated to renewable energy products, if such funds will continue to be available at all. To the extent that we are unsuccessful in being awarded any additional government grants in the future, we would lose a potential source of revenue.


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Our government grants may subject us to government audits, which could expose us to penalties.
 
We may be subject to audits by United States government agencies as part of routine audits of our activities funded by our government grants. As part of an audit, these agencies may review our performance, cost structures and compliance with applicable laws, regulations and standards and the terms and conditions of the grant. If any of our costs are found to be allocated improperly, the costs may not be reimbursed and any costs already reimbursed for such contract may have to be refunded. Accordingly, an audit could result in a material adjustment to our results of operations and financial condition. Moreover, if an audit uncovers improper or illegal activities, we may be subject to civil and criminal penalties and administrative sanctions. In addition, we devote substantial resources to our systems used to track expenditures funded by our government grants.
 
The biofuel and biopower industries are highly dependent upon government subsidies and economic incentives, and any changes in such subsidies or incentives could materially and adversely affect the growth of the industry and our ability to sell dedicated energy crops.
 
The market for renewable energy in the United States is heavily influenced by government subsidies, economic incentives and tax credits and other regulatory initiatives that impact the production, distribution and adoption of renewable energy products. For example, the United States Renewable Fuel Standard program, or RFS, currently calls for 14 billion gallons of the liquid transportation fuels sold in 2011 to come from renewable biofuels, a mandate that grows to 36 billion gallons by 2022. Of this amount, the RFS currently states that 16 billion gallons of renewable biofuels used annually by 2022 must be cellulosic biofuel, such as could be created by our switchgrass product. The RFS has been modified in the past and may be modified again in the future. In the United States, the administrator of the Environmental Protection Agency, or EPA, in consultation with the Secretary of Energy and the Secretary of Agriculture may waive certain renewable fuel standards to avert economic harm or in response to inadequate supply. The administrator of the EPA is also required to reduce the mandate for cellulosic biofuel use if projected supply for a given year falls below a minimum threshold for that year. For example, because the supply of cellulosic biofuel was projected to be very limited in 2011, the EPA determined that the final volume standard for cellulosic biofuel for 2011 would be six million gallons, well below the 250 million gallon volume requirement target specified in the Energy Independence and Security Act. Any reduction in, or waiver of, mandated requirements for fuel alternatives may cause demand for renewable biofuels to grow more slowly or decline. Our business strategy in the United States is based, in part, on these standards remaining in place. Waivers of, or reduction in, the RFS or similar mandates, could have a material adverse affect on our ability to successfully grow demand for our cellulosic feedstock products in the United States.
 
In biopower, the reduction of, or failure to implement, certain government mandates, such as Renewable Electricity Standards in the U.S. or taxes on carbon emissions, as well as incentives, subsidies and tax credits to generate electric power from low-carbon sources, may adversely affect the viability of the field trials we conduct with our collaborators. These collaborators may terminate existing field trials or elect not to progress with planned field trials absent the implementation of such incentives.
 
In addition, the United States Congress has passed legislation that extends tax credits or other economic incentives for, among other things, the production of certain renewable fuel products. For example, the United States adopted the Renewable Energy Production Tax Credit that provides federal tax incentives for renewable energy projects, and the Biomass Crop Assistance Program, or BCAP, which provides risk mitigation and production incentives to encourage growers to produce dedicated energy crops. We believe that BCAP will influence the growth of the switchgrass and miscanthus markets; however, unless extended, BCAP expires in 2012. We cannot provide assurances that these tax credits or other economic incentives will remain in place. Any reduction in or phasing out or elimination of existing tax credits, subsidies and other incentives in the United States


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and foreign markets for renewable biofuels, or any inability of us or our prospective customers to access such credits, subsidies and other incentives, may adversely affect demand for, and increase the overall cost of our renewable transportation fuels, which would adversely the prospects for our business.
 
We believe that government incentives and economic initiatives in Europe and other countries will also affect demand for our dedicated energy crops. For example, in the United Kingdom, which is a potential export market for U.S.-grown biomass, independent power providers are required to obtain a certain portion of their power from renewable resources. Any reduction or termination of government incentives or economic initiatives outside the United States could also have a material adverse effect on our business.
 
Compliance with applicable government regulations, particularly with respect to biotechnology products, is time-consuming and costly.
 
There are certain regulatory requirements affecting the field testing and commercialization of our biotechnology products in each of the markets in which we operate. In the United States, the United States Department of Agriculture, or USDA, must review and deregulate our biotechnology products prior to commercial sale. The Biotechnology Regulatory Services, or BRS, within the USDA’s Animal and Plant Health Inspection Service, or APHIS, has direct oversight of the field testing and deregulation of our biotechnology products, The deregulation process for biotechnology products is a costly, multi-year process, with no guarantee of success. The length of the deregulation process varies based on a number of factors, including the extent of the supporting information required, the nature and extent of review by the USDA, including the type and scope of the environmental review conducted, and the number and types of public comments received. For example, after the initial filing of a petition for deregulation, the USDA may ask for additional data, including data on new areas of inquiry that might require us to conduct additional field tests or analyses, which may cause delays in the deregulation process. Deregulation of a product is not a guaranteed outcome. The USDA or other regulators may also impose costly monitoring requirements on the planting of our biotechnology products.
 
In Brazil, the commercialization of biotechnology products is regulated by the National Technical Commission of Biosafety, Comissão Técnica Nacional de Biossegurança, or CTNBio under the Ministry of Science and Technology. The approval process involves data collection and analysis, environmental impact assessments and public hearings on certain products. We are not currently subject to CTNBio oversight as our current product offerings in Brazil do not include biotechnology products. However, we do anticipate introducing biotechnology products in Brazil in the future. At such time, we will be subject to the approval processes dictated by CTNBio.
 
We have not yet applied for deregulation for any of our biotech traits. Any delays in obtaining or failure to obtain deregulation or regulatory approval, as the case may be, for any of the biotechnology products in our pipeline could delay or prevent the commercialization of our products. Regulatory authorities can block the sale or import of our products or can impose conditions that delay production and sale of our products, or that make the sale of our products technically or commercially unfeasible.
 
Before the USDA will review and deregulate our products, the USDA requires us to obtain permits to plant and test our biotechnology products, and there are similar permitting requirements in Brazil. In determining whether to grant a field test permit and what conditions to impose, regulators consider any significant impacts that field tests may have on the environment and on endangered or threatened species. In the United States, the permitting process for the initial field tests typically ranges from two to four months, but this time period can be significantly longer for novel products or circumstances. While to date our permits for our field trial locations have been obtained with minimal delays, there can be no assurance that we will not encounter material delays in the future as we test new biotechnology products. If we are not able to obtain the necessary field test permits or if there


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are significant delays in the permitting process, the commercialization of our products may be delayed or prevented and our business and results of operations may be adversely affected. A prolonged delay in the regulatory process could adversely affect our ability to generate product revenues.
 
Ethical, legal and social concerns about biotechnology products could limit or prevent the use of our products and technologies, which could negatively affect our ability to generate revenue.
 
Some of our products in development contain biotech traits. The commercial success of our products that contain biotech traits may be adversely affected by claims that biotechnology plant products are unsafe for consumption or use, pose risks of damage to the environment and create legal, social and ethical dilemmas. For example, some countries, primarily in the European Union, have instituted a de facto moratorium on the planting of some genetically engineered seeds. The import of biomass grown from genetically engineered seeds may also be regulated by the European Union. While we are not currently selling seeds containing biotech traits into the European Union, we plan to do so in the future. In addition, Brazil’s biosafety law prohibits the use, sale, registration, patenting and licensing of genetic use restriction technologies, which are a class of genetic engineering technologies that allow companies to introduce seeds whose sterile offspring cannot reproduce, preventing farmers from re-planting seeds from their harvest. While our current sweet sorghum products are not subject to this restriction, we may in the future introduce biotech traits that may be subject to such regulation. If we are not able to overcome these concerns and comply with these regulations, our products may not achieve market acceptance. Any of the risks discussed below could result in expenses, delays or other impediments to our development programs or the market acceptance and commercialization of our products that contain biotech traits. Our ability to develop and commercialize one or more of our technologies and products could be limited or prevented by the following factors:
 
  •  Public attitudes about the safety and environmental hazards of, and ethical concerns over, genetic research and biotechnology products, which could influence public acceptance of our technologies and products;
 
  •  Public attitudes regarding, and potential changes to laws governing, ownership of genetic material, which could weaken our intellectual property rights with respect to our genetic material and discourage collaborators from supporting, developing or commercializing our products and technologies;
 
  •  Governmental reaction to negative publicity concerning genetically engineered plants, which could result in greater government regulation of genetic research and derivative products; and
 
  •  Failure to maintain or secure consumer confidence in, or to maintain or receive governmental approvals for, our products.
 
We cannot predict whether or when any jurisdiction will change its regulations with respect to biotechnology products. Problems with any product could lead to increased scrutiny or regulation for our products. Limitations on the development of biotechnology products could be imposed that could delay, prevent or make more costly the development of such products, which would negatively affect our ability to commercialize products using our traits.
 
Advocacy groups have engaged in publicity campaigns and filed lawsuits in various countries against companies and regulatory authorities, seeking to halt biotechnology approval activities or influence public opinion against genetically engineered products. On occasion, there has been vandalism and destruction of property of companies in the biotechnology industry.


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Our non-biotechnology products, the products of third parties or the environment may be negatively affected by the unintended appearance of our transgenes.
 
The development and commercial success of our non-biotechnology products may be delayed or negatively affected because of adverse public perception or regulatory concerns about the safety of our products and the potential effects of these products on other plants, animals, human health and the environment. The potential for unintended but unavoidable trace amounts, sometimes called “adventitious presence”, of transgenes in conventional seed, or in the grain or products produced from conventional or organic crops, is another factor that could affect general public acceptance of these traits. For example, our current sweet sorghum, high biomass sorghum and switchgrass products have been produced exclusively through conventional breeding and have not been genetically engineered by us. It is possible, however, that trace amounts of our transgenes are nevertheless in our conventional products. In addition, trace amounts of transgenes may unintentionally be found outside our containment area in the products of third parties, which may result in negative publicity and claims of liability brought by such third parties against us. Furthermore, in the event of an unintended dissemination of our genetically engineered materials to the environment, we could be subject to claims by multiple parties, including environmental advocacy groups, as well as governmental actions such as mandated crop destruction, product recalls or additional stewardship practices and environmental cleanup or monitoring.
 
Ethical, legal and social concerns about land use could limit or prevent the widespread adoption of our products, which could negatively affect our ability to generate revenue.
 
The commercial success of our products also may be adversely affected by claims that the production of bioenergy displaces land that would otherwise be used for food and feed production, leading to shortages and higher prices for food and feed commodities. These claims are based, in part, on the assumption that there is a scarcity of available land for crop production, productivity is uniform across the globe and that productivity will remain flat over time. While these assumptions are not universally accepted, their acceptance by legislatures or advocacy groups could harm our ability to sell our products. The increased use of land for bioenergy production may also lead to claims that the increased planting of other crops in other regions may cause land clearing, such as in the Brazilian rainforest, and subsequent greenhouse gas releases — a theory known as indirect land use change. This theory proposes that such indirect effects, and their related greenhouse gas emissions should be applied to the emissions life cycle of bioenergy feedstocks, including dedicated energy crops. The perception that our products are resulting in higher greenhouse gas emissions could disadvantage our products related to other potential energy sources, or make it more difficult for our products to meet regulatory requirements for reduced emissions.
 
Development and commercialization, if any, of our products may incur scrutiny under the Convention on Biological Diversity Treaty.
 
The Convention on Biological Diversity, or the Convention, is an international treaty that was adopted at the Earth Summit in Rio de Janeiro, Brazil in 1992. The treaty provides that if a company uses genetic resources, such as an indigenous plant, from a participating country to develop a product, then such company must obtain the prior informed consent of the participating country and owes fair and equitable compensation to such country. Although the United States is not a participating country, most countries where we currently obtain or may obtain germplasm in the future, have ratified the treaty and are currently participants in the Convention. We may fall under scrutiny of the Convention with respect to the development or commercialization of any of our products derived from the germplasm originating from any of the countries that are participants in the Convention. There can be no assurances that the government of a participating country will not assert that it is entitled to fair and equitable compensation from us. Such compensation, if demanded, may make commercialization of our products not feasible.


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Our business is affected by changes in general economic conditions and a prolonged downturn could affect the demand for our products and our ability to fund our working capital.
 
Economic conditions in the United States, Brazil and Europe could adversely affect our efforts to achieve profitability. The purchasing decisions of utilities, mill operators, growers and other potential customers, and their ability to timely pay for our products, are impacted by their economic health. We may have to regularly extend credit to our customers to enable them to acquire seeds at the beginning of the growing season on terms that permit payment following the sales of their products. These credit practices may expose us to credit risk of utilities, mill operators and growers and other potential customers, and combined with the seasonality of our sales, make us dependent on our ability to fund our working capital requirements through other means. If the current difficult economic conditions continue or worsen, the economic health of our customers and potential customers could further deteriorate.
 
Our activities are currently conducted at limited number of locations, which makes us susceptible to damage or business disruptions caused by natural disasters.
 
Our headquarters and certain research and development operations are located at a single facility in Thousand Oaks, California. Our main breeding station is located at our College Station Research Center near College Station, Texas, with additional breeding and agronomy trials situated in select locations across the world, including the Americas, Europe and Asia. Our seed production takes place primarily in the United States and Puerto Rico, as well as Argentina, Bolivia and Brazil. Warehousing for seed storage is located primarily in Texas and the state of São Paulo, Brazil. We take precautions to safeguard our facilities, including insurance, health and safety protocols, and off-site storage of critical research results and computer data. However, a natural disaster, such as a hurricane, fire, flood, tornado or earthquake, could cause substantial delays in our operations, damage or destroy our equipment, inventory or development projects, and cause us to incur additional expenses. The insurance we maintain against natural disasters may not be adequate to cover our losses in any particular case.
 
We rely on the experience and expertise of our senior management team and other key personnel.
 
We depend on the experience and expertise of our senior management team and other key personnel, many of whom have been with our company for more than a decade. Our senior management team and key personnel bring extensive experience in the seed industry, agricultural biotechnology and plant genetics. The loss or unavailability of key members of our senior management team or other key personnel could impact the execution of our business strategy and make it more difficult to maintain and expand our important relationships in the bioenergy industry. The replacement of key members of our senior management team or other key personnel likely would involve significant time and costs.
 
If we are unable to recruit or retain qualified personnel, particularly in Brazil, our development and commercialization efforts may be significantly delayed.
 
Competition for qualified personnel is intense among agricultural biotechnology and other technology-based businesses, particularly for personnel with the appropriate level of education, experience and training. We may not be able to recruit and retain such personnel at compensation levels consistent with our existing compensation structure. The continued appreciation of the Brazilian Real against the U.S. dollar will make it more difficult for us to meet compensation expectations of Brazilian personnel. In addition, in making employment decisions, job candidates often consider the value of equity they may receive in connection with their employment. Therefore, significant volatility in the price of our stock after this offering may adversely affect our ability to attract or retain personnel. Competition for qualified personnel in Brazil is particularly intense due to the importance of the


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agricultural industry in Brazil and the recent increased activity levels of U.S. agricultural or renewable energy companies in Brazil, including Amyris Biotechnologies, Inc. and Monsanto Company.
 
If we lose qualified personnel or are unable to attract, retain and integrate additional highly trained and motivated personnel, particularly for our research and development activities, our ability to advance our product development and continue our commercialization efforts may be delayed or unsuccessful.
 
Unexpected fluctuations in our quarterly operating results may cause our stock price to fluctuate widely.
 
A large proportion of our costs are fixed, due in part to our significant research and development and production costs and general and administrative expenses. Thus, even a small decline in revenue could disproportionately affect our quarterly operating results and could cause such results to differ materially from expectations. If this occurs, we may fail to meet analyst and investor expectations, which could cause our stock price to decline. Other factors that could affect our quarterly operating results or cause them to differ materially from expectations include:
 
  •  demand for and acceptance of our products;
 
  •  weather conditions or the occurrence of natural disasters;
 
  •  changes in government regulations and incentives;
 
  •  competitive pressures resulting in lower selling prices; and
 
  •  unanticipated delays or problems in the introduction of new products.
 
We may require additional financing in the future and may not be able to obtain such financing on favorable terms, if at all, which could force us to delay, reduce or eliminate our research and development activities.
 
We will continue to need capital to fund our research and development projects and to provide working capital to fund other aspects of our business. If our capital resources are insufficient to meet our capital requirements, we will have to raise additional funds. If future financings involve the issuance of equity securities, our existing stockholders would suffer dilution. If we are able to raise additional debt financing, we may be subject to restrictive covenants that limit our operating flexibility. We may not be able to raise sufficient additional funds on terms that are favorable to us, if at all. If we fail to raise sufficient funds and continue to incur losses, our ability to fund our operations, take advantage of strategic opportunities, develop and commercialize products or technologies, or otherwise respond to competitive pressures could be significantly limited. If this happens, we may be forced to delay or terminate research and development programs or the commercialization of products, curtail operations or obtain funds through collaborative and licensing arrangements that may require us to relinquish commercial rights, or grant licenses to our technology on terms that are not favorable to us. If adequate funds are not available, we will not be able to successfully execute on our business strategy or continue our business.
 
We expect to derive a portion of our revenues from markets outside the United States, including Brazil, which will subject us to additional business risks.
 
Changes in exchange rates between the U.S. dollar and other currencies will result in increases or decreases in our costs and earnings, and also may affect the book value of our assets outside the United States. To date, most of our contracts have been entered into in the United States and accordingly have been denominated in U.S. dollars. Going forward we anticipate that our sales will be denominated in the local currency of the country in which the sale occurs. In addition, most of our operating expenses to date have been denominated in the currencies of the countries in which our operations are located, primarily the United States and Brazil. As a result, while our revenue and


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operating expenses are mostly hedged on a transactional basis, the translation of our operating results into U.S. dollars may be adversely impacted by strengthening U.S. currency.
 
In addition, international operations are subject to a number of other risks and uncertainties, including:
 
  •  changes in political, social or economic conditions;
 
  •  tariffs, trade protection measures and trade agreements;
 
  •  import or export licensing requirements;
 
  •  changes in regulatory requirements;
 
  •  reduced protection for intellectual property rights in some countries;
 
  •  economic downturns, civil disturbances or political instability;
 
  •  difficulties and costs of staffing and managing international operations;
 
  •  fluctuations in currency exchange rights;
 
  •  land reform movements;
 
  •  price controls;
 
  •  nationalization; and
 
  •  potentially burdensome taxation.
 
In the past, the Brazilian economy was characterized by frequent and occasionally extensive intervention by the Brazilian government and unstable economic cycles. The Brazilian government has changed in the past, and may change in the future, monetary, taxation, credit, tariff and other policies to influence the course of Brazil’s economy. For example, the government’s actions to control inflation have at times involved setting wage and price controls, adjusting interest rates, imposing taxes and exchange controls and limiting imports into Brazil. The Brazilian government has also in the past placed significant restrictions on the ability of foreign persons and companies to acquire property in Brazil. We have no control over, and cannot predict, what policies or actions the Brazilian government may take in the future. Any of these actions could adversely affect our international operations and, consequently, our results of operations.
 
Our ability to use our net operating loss carry forwards to offset future taxable income may be subject to certain limitations.
 
As of August 31, 2010, we had approximately $154.2 million of federal and $133.4 million of state operating loss carry-forwards available to offset future taxable income, which expire in varying amounts beginning in 2018 for federal and 2016 for state purposes if unused. It is possible that we will not generate taxable income in time to use these loss carry-forwards before their expiration. In addition, under Section 382 of the Internal Revenue Code, or Code, a corporation that undergoes an “ownership change” is subject to limitations on its ability to utilize its pre-change net operating loss carry forwards, or NOLs, to offset future taxable income. We have not completed a Section 382 analysis to determine if an ownership change has occurred. Until such analysis is completed, we cannot be sure that the full amount of the existing NOLs will be available to us, even if we do generate taxable income before their expiration.
 
We use hazardous materials in our business. Any claims relating to improper handling, storage or disposal of these materials could be time consuming and costly.
 
Our research and development processes involve the controlled use of hazardous materials, including chemical and biological materials. Federal, state and local laws and regulations govern the use, manufacture, storage, handling and disposal of these materials. Our operations also produce


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hazardous waste. We cannot eliminate entirely the risk of accidental contamination or discharge and any resultant injury from these materials. We may face liability for any injury or contamination that results from our use or the use by third parties of these materials, which depending on the severity of the injury or contamination could be significant. In addition, compliance with applicable environmental laws and regulations may be expensive, and current or future environmental regulations may impair our research, development or production efforts.
 
We may suffer liabilities relating soil and/or groundwater contamination at current and former properties and at third-party sites to which we sent hazardous wastes for disposal.
 
We are exposed to environmental risks associated with the ownership and operation of real property and the disposal of hazardous wastes. Environmental laws can require current owners and operators of real property to remediate soil and groundwater contamination even if such contamination was caused by another party, such as a former owner or operator. These laws can also require companies to clean up real property that they formerly owned or operated if releases of hazardous materials or wastes occurred during the period of their ownership or operation. Moreover, in certain circumstances these laws require companies to clean up third-party sites to which hazardous wastes were sent for disposal, notwithstanding that the original disposal activity accorded with all regulatory requirements. The discovery of previously unknown contamination at our current or former facilities, or at third-party sites to which we sent hazardous wastes for disposal, could require us to conduct or fund expensive cleanup efforts, which could materially and adversely affect our operating results.
 
We may be sued for product liability and if such lawsuits were determined adversely, we could be subject to substantial damages.
 
We may be held liable if any product we develop, or any product that uses or incorporates, any of our technologies, causes injury or is found otherwise unsuitable during product testing, production, marketing or sale. For example, the detection of unintended biotechnology material in pre-commercial seed, commercial seed varieties or the crops and products produced may result in the inability to market the crops grown, resulting in potential liability for us as the seed producer or technology provider. In the event this was to occur, we could be subject to claims by multiple parties based not only on the cost of our products but also on their lost profits and business opportunities. In addition, the detection of unintended biotechnology material in our seeds or in the environment could result in governmental actions such as mandated crop destruction, product recalls or environmental cleanup or monitoring. Concerns about seed quality related to biotechnology could also lead to additional regulations being imposed on our business, such as regulations related to testing procedures, mandatory governmental reviews of biotechnology advances, or the integrity of the food supply chain from the farm to the finished product.
 
We currently have limited product liability insurance coverage and additional insurance may be prohibitively expensive, or may not fully cover potential liabilities. If we are unable to obtain sufficient insurance coverage at an acceptable cost or otherwise or if the amount of any claim against us exceeds the coverage under our policy, we may face significant expenses.
 
Risks Related to our Intellectual Property
 
Our inability to adequately protect our proprietary technologies and products could harm our competitive position.
 
Our success depends in part on our ability to obtain patents and maintain adequate protection of our other intellectual property for our technologies and products in the United States and other countries. The laws of some foreign countries do not protect proprietary rights to the same extent as the laws of the United States, and many companies have encountered significant problems in protecting their proprietary rights in these foreign countries. These problems can be caused by, for


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example, a lack of rules and methods for defending intellectual property rights. Many countries do not allow patenting of genetically engineered plants. The legal systems of certain countries do not favor the enforcement of patents and other intellectual property protection, particularly those relating to biotechnology. This could make it difficult for us to stop the infringement of our patents or misappropriation of our other intellectual property rights. Proceedings to enforce our patents and other proprietary rights in foreign jurisdictions could result in substantial costs and divert our efforts and attention from other aspects of our business. Accordingly, our efforts to enforce our intellectual property rights in such countries may be inadequate to obtain a significant commercial advantage from the intellectual property that we develop. Even if we enforce our rights aggressively, injunctions, fines and other penalties may be insufficient to deter violations of our intellectual property rights. Changes in either the patent laws or in interpretations of patent laws in the United States and other countries may diminish the value of our intellectual property.
 
The patent positions of biotechnology companies, including our patent position, are generally uncertain and involve complex legal and factual questions. We will be able to protect our proprietary rights from unauthorized use by third parties only to the extent that our proprietary technologies are covered by valid and enforceable patents. We will apply for patents covering both our technologies and products as we deem appropriate. However, we cannot assure you that any pending or future patent applications held by us will result in an issued patent, or that if patents are issued to us, such patents will provide meaningful protection against competitors or against competitive technologies. Our existing patents and any future patents we obtain may not be sufficiently broad to prevent others from practicing our technologies or from developing competing products. Furthermore, others may independently develop similar or alternative technologies or design around our patented technologies. In addition, our patents may be challenged, invalidated or fail to provide us with any competitive advantages.
 
The value of our intellectual property could diminish due to technological developments or challenges by competitors, making our products less competitive.
 
Our intellectual property rights are important to the operation of our business and to our early mover advantage in crop biotechnology. We rely on a combination of patents, plant variety protection, plant breeders’ rights, copyrights, trademarks, trade secret laws, confidentiality provisions, and licensing arrangements to establish and protect our intellectual property. However, the importance of technology development and intellectual property protection in the agricultural industry increases the risk that technological advances by others could render our products less competitive. Our business could be negatively affected by any of the following:
 
  •  our issued patents, Plant Variety Protection certificates, plant breeders’ rights and trademark registrations may be successfully challenged by our competitors;
 
  •  our pending patent, Plant Variety Protection certificates, plant breeders’ rights and trademark registration applications may not be allowed or may be challenged successfully by our competitors;
 
  •  our products may inadvertently use the technology of others and, therefore, require us to obtain intellectual property licenses from other parties in order for us to sell our products;
 
  •  we may be unable to obtain intellectual property licenses that are necessary or useful to our business on favorable terms, or at all;
 
  •  new technology that is independently developed by others may supersede our technology and make our products less desirable or more costly in the marketplace; and
 
  •  competitors may design around our patented technologies or may reverse engineer our trade secret technologies.


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While we have exclusive rights to certain proprietary lines of switchgrass, miscanthus, high biomass sorghum and sweet sorghum through our collaborations with leading institutions, other parties may have access to certain lines of switchgrass, miscanthus, high biomass sorghum or sweet sorghum developed or released by such institutions, proprietary lines of such crops from other sources, and publicly available lines of such crops, from which they may develop products that compete with our products.
 
Litigation or other proceedings or third party claims of infringement could require us to spend time and money and could severely disrupt our business.
 
Our commercial success depends on not infringing patents or proprietary rights of third parties, nor breaching any licenses or other agreements that we have entered into with regard to our technologies, products and business. The patent positions of biotechnology and seed companies involve complex legal and factual questions and, therefore, enforceability cannot be predicted with certainty. Patents, if issued, may be challenged, invalidated or circumvented. We cannot be sure that relevant patents have not been issued that could block our ability to obtain patents or to operate as we would like without infringing patents or proprietary rights of other parties.
 
The biotechnology and seed industries have a history of litigation regarding patents and other intellectual property rights. Many biotechnology companies have employed intellectual property litigation as a way to gain a competitive advantage. We cannot assure you that we will not be sued by third parties for infringement of patents they may have relating to biotechnological traits or technologies in various crops.
 
Should any of our competitors have filed patent applications or obtain patents that claim inventions also claimed by us, we may have to participate in an interference proceeding declared by the U.S. Patent and Trademark Office to determine priority of invention and, thus, the right to a patent for these inventions in the United States. Such a proceeding could result in substantial cost to us even if the outcome is favorable. Even if successful on priority grounds, an interference proceeding may result in loss of claims based on patentability grounds raised in the proceeding. If we become involved in litigation or interference proceedings declared by the U.S. Patent and Trademark Office to defend our intellectual property rights or as a result of alleged infringement of the rights of others, or oppositions or other intellectual property proceedings outside of the United States, we might have to spend significant amounts of money to resolve such matters. We are aware of a significant number of pending patent applications relating to biotechnological traits or technologies in various crops filed by third parties.
 
Even if we prevail, litigation, interference proceedings or opposition proceedings could result in significant legal fees and other expenses, could divert our management time and efforts and could severely disrupt our business. Uncertainties resulting from initiation and continuation of any patent or related litigation could harm our ability to compete.
 
An adverse ruling arising out of any intellectual property dispute could undercut or minimize our intellectual property position. An adverse ruling that our operations violate a third party’s intellectual property rights could also subject us to significant liability for damages, prevent us from using processes or products, or require us to license disputed rights from third parties. Claims of intellectual property infringement against us may require us to enter into costly royalty or license agreements, subject us to substantial damage claims or cause us to stop using such technology absent a license agreement. Although patent and intellectual property disputes in the biotechnology area are often settled through licensing or similar arrangements, costs associated with these arrangements may be substantial and could include ongoing royalties. Furthermore, necessary licenses may not be available to us on satisfactory terms, if at all.


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Third parties may infringe on our intellectual property rights, and we may expend significant resources enforcing our rights or be competitively disadvantaged.
 
If we fail to protect our intellectual property rights from infringement by third parties, our competitive position could suffer, which could make it more difficult to grow our business. We may not be able to detect or prevent infringement of our intellectual property or may lose our competitive position in the market before we do so.
 
Confidentiality agreements with employees and others may not adequately prevent disclosure of trade secrets and other proprietary information.
 
In order to protect our proprietary technology and processes, we also rely in part on trade secret protection for our confidential and proprietary information. For example, we consider our genetic transformation methods, markers for marker-assisted breeding and sequence databases as trade secrets. We have taken security measures to protect our trade secrets and proprietary information. These measures may not provide adequate protection for our trade secrets or other proprietary information. We also seek to protect our proprietary information by entering into confidentiality agreements with employees, with potential and actual collaborators and licensees and with consultants and other advisors. These agreements may not effectively prevent disclosure of confidential information and may not provide an adequate remedy in the event of unauthorized disclosure of confidential information. In addition, others may independently develop substantially equivalent proprietary information or techniques and trade secret laws do not allow us to protect against such independent development. Costly and time-consuming litigation could be necessary to enforce and determine the scope of our proprietary rights, and failure to obtain or maintain trade secret protection could adversely affect our competitive business position.
 
We have received funding from U.S. government agencies, which could negatively affect our intellectual property rights.
 
Some of our research and development activities have been funded by grants from U.S. government agencies. For example, a portion of our research and development used to develop our nitrogen use efficiency trait was funded by a U.S. Department of Energy ARPA-E grant. When new technologies are developed with U.S. government funding, the government obtains certain rights in any resulting patents and technical data, generally including, at a minimum, a non-exclusive, nontransferable license authorizing the government to use the invention or technical data for non-commercial purposes. U.S. government funding must be disclosed in any resulting patent applications, and our rights in such inventions will normally be subject to government license rights, periodic progress reporting, foreign manufacturing restrictions and march-in rights.
 
March-in rights refer to the right of the U.S. government, under certain limited circumstances, to require us to grant a license to technology developed under a government grant to a responsible applicant, or, if we refuse, to grant such a license itself. March-in rights can be triggered if the government determines that we have failed, within a reasonable time, to take effective steps to achieve practical application of a technology or, if action is necessary to alleviate health or safety needs, to meet requirements for public use specified by federal regulations or to give preference to U.S. industry. We may also enter into collaborations with entities outside the United States that receive government funding or, in the future, we may apply for government funding from other countries. Regulations in these countries may provide for similar march-in rights. Any government’s rights in our intellectual property may lessen its commercial value, which could adversely affect our business.


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Risks Related to this Offering and Ownership of our Common Stock
 
No public market for our common stock currently exists and an active trading market may not develop or be sustained following this offering.
 
Prior to this offering, there has not been a public market for our common stock. An active and liquid trading market for our common stock may not develop following this offering or if it does develop, it may not be sustained. The lack of a liquid trading market may make it more difficult for you to sell your shares when you wish to sell them or at a price that you consider attractive. The lack of a liquid trading market may also reduce the fair market value of your shares. Also, an inactive trading market for our shares may negatively affect our ability to raise equity capital in the future by selling shares in a public offering or make it more difficult to acquire other companies by using our common stock as consideration.
 
The price of our common stock may be volatile and you may not be able to sell your shares at or above the initial public offering price.
 
The initial public offering price for our shares will be determined by negotiations between us and representatives of the underwriters and may not be indicative of prices that will prevail in the stock market following this offering. The market price for our common stock may decline below the initial public offering price and you may not be able to sell your shares at or above the initial public offering price. Our stock price may be subject to wide fluctuations in response to the factors listed in this section and others beyond our control, including:
 
  •  actual or projected fluctuations in our financial condition and operating results;
 
  •  our cash and cash equivalents position;
 
  •  actual or projected changes in our growth rate relative to our competitors;
 
  •  actual or projected fluctuations in our competitors’ financial condition or operating results;
 
  •  announcements of technological innovations by us, our collaborators or our competitors;
 
  •  announcements by us, our collaborators or competitors of significant acquisitions, strategic partnerships, joint ventures or capital commitments;
 
  •  the entry into, modification or termination of collaborative arrangements;
 
  •  changes in our customer base;
 
  •  additions or departures of key management or other key personnel;
 
  •  competition from existing products or new products that may emerge;
 
  •  issuances of new or updated research reports by securities or industry analysts;
 
  •  fluctuations in the share prices of companies perceived by investors to be comparable to us;
 
  •  disputes or other developments related to proprietary rights, including patents, litigation matters, the countries in which we source our germplasm, and our ability to obtain patent protection for our technologies;
 
  •  disputes or other developments relating to genetically engineered products, including claims of adventitious presence or environmental harm;
 
  •  changes in existing laws, regulations and policies applicable to our business and products, including the United States Renewable Fuel Standard program, and the adoption or failure to adopt additional carbon emissions regulations;
 
  •  announcements or the expectation of raising additional financing;


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  •  sales of our common stock by us, our insiders or other stockholders;
 
  •  general market conditions in our industry; and
 
  •  general economic conditions, including the impact of the recent financial crisis.
 
The stock markets in general, and the market for renewable energy stocks in particular, have experienced extreme volatility that have affected and continue to affect the trading prices of equity securities of many companies. These market fluctuations often have been unrelated or disproportionate to the operating performance of those companies. These fluctuations, as well as general economic, political and market conditions such as recessions, interest rate changes or international currency fluctuations, may negatively impact the market price of our common stock. In the past, companies that have experienced volatility in the market price of their stock have been subject to securities class action litigation. We may be the target of this type of litigation in the future. Securities litigation against us could result in substantial costs and divert our management’s attention from other business concerns.
 
A significant portion of our total outstanding shares of common stock is restricted from immediate resale, but may be sold into the public market in the near future. If there are substantial sales of our common stock, or the perception that these sales could occur in the future, the trading price of our common stock could decline.
 
The trading price of our common stock could decline as a result of sales of a large number of shares of our common stock in the public market after this offering. The perception that these sales could occur may also depress the trading price of our common stock. Based on the number of shares outstanding as of          , 2011, we will have           shares of common stock outstanding after the completion of this offering. Of these shares, the common stock sold in this offering will be freely tradable in the United States, except for any shares purchased by our “affiliates” as defined in Rule 144 under the Securities Act of 1933, as amended, or the Securities Act.
 
The holders of           shares of common stock have agreed with the underwriters, subject to certain exceptions, not to offer, sell, pledge or otherwise dispose of any of their common stock during the period beginning on the date of this prospectus and continuing through the date 180 days after the date of this prospectus (subject to extension under certain circumstances), except with the prior written consent of Goldman, Sachs & Co.
 
However, Goldman, Sachs & Co. can waive the provisions of these lock-up agreements and allow these stockholders to sell their shares at any time. After the expiration of the 180-day restricted period (subject to extension under certain circumstances), these shares may be sold in the public market in the United States, subject to prior registration in the United States, if required, or reliance upon an exemption from U.S. registration under Rule 144 or Rule 701 under the Securities Act. See “Shares Eligible for Future Sale”.
 
     
Number of Shares and
   
% of Total Outstanding
 
Date Available for Sale into Public Market
 
                    or               %     
  Immediately after this offering.
                    or               %
  90 days after the date of this prospectus.
                    or               %
  180 days after the date of this prospectus.
                    or               %
  From time to time after the date 180 days after the date of this prospectus.
 
In addition, as of          , 2011, there were           shares of common stock issuable upon the exercise of outstanding options or warrants that will become eligible for sale in the public market to the extent permitted by applicable vesting requirements, the lock-up agreements discussed in “Underwriting” and Rules 144 and 701 of the Securities Act.


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Holders owning an aggregate of           shares of common stock will be entitled, under contracts providing for registration rights, to require us to register shares of our common stock owned by them for public sale in the United States, subject to the restrictions of Rule 144. See “Description of Capital Stock — Registration Rights”. In addition, we intend to file a registration statement to register approximately           shares previously issued or reserved for future issuance under our equity compensation plans and agreements. Upon effectiveness of such registration statement, subject to the satisfaction of applicable exercise periods and, in certain cases, the lock-up agreements discussed in “Underwriting”, the shares of common stock issued upon exercise of outstanding options will be available for immediate resale in the United States in the open market.
 
If securities or industry analysts do not publish research or reports about our business or our industry, or publish negative reports about our business or our industry, our stock price and trading volume could decline.
 
The trading market for our common stock will be influenced by the research and reports that securities or industry analysts publish about us, our business, our industry or our competitors. If one or more of the analysts who cover us change their recommendation regarding our stock adversely, change their opinion of the prospects for our company in a negative manner, or provide more favorable relative recommendations about our competitors, our stock price would likely decline. If one or more of these analysts cease coverage of our company or fail to regularly publish reports on us, we could lose visibility in the financial markets, which could cause our stock price or trading volume to decline.
 
Purchasers in this offering will experience immediate and substantial dilution in the book value of their investment.
 
The initial public offering price will be substantially higher than the net tangible book value per share of our outstanding common stock immediately after this offering. Therefore, if you purchase shares of our common stock in this offering, you will experience immediate and substantial dilution of approximately $      per share in the price you pay for shares of our common stock as compared to its net tangible book value, assuming an initial public offering price of $      per share, the midpoint of the range set forth on the cover page of this prospectus. If outstanding options and the outstanding warrants that do not expire upon completion of this offering are exercised, you will experience further dilution. In addition, following this offering, purchasers in this offering will have contributed     % of the total consideration paid by our stockholders to purchase shares of common stock, in exchange for acquiring approximately     % of our total outstanding shares as of          , 2011. To the extent that outstanding options and warrants to purchase shares of common stock are exercised, there will be further dilution. For further information on this calculation, see the “Dilution” section of this prospectus.
 
We will incur significant increased costs as a result of operating as a public company, and our management will be required to devote substantial time to comply with the laws and regulations affecting public companies.
 
We have never operated as a public company. As a public company, we will incur significant legal, accounting and other expenses that we did not incur as a private company, including costs associated with public company reporting and corporate governance requirements, in order to comply with the rules and regulations imposed by the Sarbanes-Oxley Act, as well as rules implemented by the SEC and the Nasdaq Global Market. Our management and other personnel will need to devote a substantial amount of time to these compliance initiatives and our legal and accounting compliance costs will increase.
 
The Sarbanes-Oxley Act requires, among other things, that we maintain effective internal controls over financial reporting and disclosure controls and procedures. In particular, commencing in 2012, we must perform system and process evaluations and testing of our internal control over


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financial reporting to allow management and our independent registered public accounting firm to report on the effectiveness of our internal controls over financial reporting, as required by Section 404 of the Sarbanes-Oxley Act. Our testing, or the subsequent testing by our independent registered public accounting firm, may reveal deficiencies in our internal control over financial reporting that are deemed to be material weaknesses. Our compliance with Section 404 will require that we incur substantial accounting expense and management time on compliance-related issues. Moreover, if we are not able to comply with the requirements of Section 404 in a timely manner, or if we or our independent registered public accounting firm identify deficiencies in our internal control over financial reporting that are deemed to be material weaknesses, we could lose investor confidence in the accuracy and completeness of our financial reports, which could cause our stock price to decline.
 
Anti-takeover provisions in our certificate of incorporation and bylaws and under Delaware law could delay or prevent an acquisition of our company, even if the acquisition may be beneficial to our stockholders.
 
Provisions in our amended and restated certificate of incorporation and our bylaws, both of which will become effective upon the completion of this offering, may delay or prevent an acquisition of our company deemed undesirable by our board of directors. Among other things, our amended and restated certificate of incorporation and bylaws will (i) provide for a board of directors that is divided into three classes, with staggered three-year terms, (ii) provide that all stockholder action must be effected at a duly called meeting of the stockholders and not by a consent in writing, (iii) provide that only our board of directors, the chairman of the board of directors, our chief executive officer (or president in the absence of a chief executive officer) may call a special meeting of the stockholders, (iv) provide for the ability of our board of directors to issue undesignated preferred stock, (v) require that any amendment to the amended and restated certificate of incorporation be approved by a 662/3 stockholder vote, and (vi) establish advance notice requirements for nominations for election to our board of directors and for proposing matters that can be acted upon at stockholders meetings. These provisions may also frustrate or prevent any attempt by our stockholders to replace or remove our current management by making it more difficult for stockholders to replace members of our board of directors who are responsible for appointing the members of our management team. As a Delaware corporation, we are subject to the provisions of Section 203 of the Delaware General Corporation Law, which prohibits, with some exceptions, stockholders owning in excess of 15% of our outstanding stock from merging or combining with us without board of directors or stockholder approval. Although we believe these provisions together provide for an opportunity to receive higher bids by requiring potential acquirers to negotiate with our board of directors, they would apply even if an offer to acquire our company may be considered beneficial by some stockholders and could limit the opportunity for our stockholders to receive a premium for their shares.
 
Concentration of ownership among our existing officers, directors and principal stockholders may prevent other stockholders from influencing significant corporate decisions.
 
Based on the number of shares outstanding as of          , 2011, when this offering is completed, our officers, directors and existing stockholders who hold at least 5% of our stock will together beneficially own approximately     % of our outstanding common stock and if the underwriters’ option to purchase additional shares is exercised in full, such persons will beneficially own, in the aggregate, approximately     % of our outstanding common stock. If these officers, directors and principal stockholders or a group of our principal stockholder act together, they will be able to exert a significant degree of influence over our management and affairs and exercise a significant level of control over all matters requiring stockholder approval, including the election of directors and approval of mergers or other business combination transactions. This concentration of ownership may have the effect of delaying or preventing a change in control of our company or changes in management and will make the approval of certain transactions difficult or impossible without the support of these stockholders.


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After the completion of this offering, we do not expect to declare any dividends in the foreseeable future.
 
After the completion of this offering, we do not anticipate declaring any cash dividends to holders of our common stock in the foreseeable future. Our existing loan agreement prohibits us from paying dividends on our capital stock. Consequently, investors may need to rely on sales of their common stock after price appreciation, which may never occur, as the only way to realize any future gains on their investment. Investors seeking cash dividends should not purchase our common stock.
 
Our management will have broad discretion over the use of the net proceeds from this offering and may not apply the proceeds in ways that increase the value of your investment.
 
Although we currently intend to use the net proceeds from this offering as described in the “Use of Proceeds” section of this prospectus, our management will have broad discretion in the application of the net proceeds. Our management may not apply the net proceeds in ways that ultimately increase the value of your investment. You will not have the opportunity to influence our decisions on how to use the net proceeds from this offering.


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SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS
 
This prospectus, including the sections entitled “Prospectus Summary”, “Risk Factors”, “Use of Proceeds”, “Management’s Discussion and Analysis of Financial Condition and Results of Operations”, and “Business”, contains forward-looking statements. All statements, other than statements of historical facts contained in this prospectus, including statements regarding our efforts to develop and commercialize our products, our short-term and long-term business strategies, market and industry expectations and future results of operations and financial position, are forward-looking statements. In many cases, you can identify forward-looking statements by terms such as “may”, “will”, “should”, “expect”, “plan”, “anticipate”, “could”, “intend”, “target”, “project”, “contemplate”, “believe”, “estimate”, “potential”, “continue” or other similar words.
 
We based these forward-looking statements largely on our current expectations and projections about future events or trends that we believe may affect our business and financial performance. These forward-looking statements involve known and unknown risks and uncertainties that may cause our actual results, performance or achievements to materially differ from any future results, performance or achievements expressed or implied by these forward-looking statements. We have described in the “Risk Factors” section and elsewhere in this prospectus the material risks and uncertainties that we believe could cause actual results to differ from these forward-looking statements. Because forward-looking statements are inherently subject to risks and uncertainties, some of which we cannot predict or quantify, you should not rely on these forward-looking statements as guarantees of future results, performance or achievements.
 
The forward looking statements in this prospectus represent our views as of the date of this prospectus. We undertake no obligation to update publicly, except to the extent required by law, any forward-looking statements for any reason after the date of this prospectus to conform these statements to actual results or to changes in our expectations.
 
MARKET AND INDUSTRY DATA
 
Market data and certain industry data and forecasts included in this prospectus were obtained from internal company surveys, market research, consultant surveys, publicly available information, governmental agency reports and industry publications and surveys, including reports by the following authorities:
 
  •  The U.S. Energy Information Administration;
 
  •  The International Energy Agency;
 
  •  The Renewable Fuels Association; and
 
  •  Brazilian Sugarcane Industry Association.
 
This information involves a number of assumptions and limitations and you are cautioned not to give undue weight to this information. These industry and government publications, surveys and forecasts generally indicate that the information has been obtained from sources believed to be reliable, but that the accuracy and completeness of such information is not guaranteed. Although we believe the third party market and industry data and forecasts included in the prospectus are generally reliable, we have not independently verified any of the data from third party sources nor have we ascertained the underlying economic assumptions relied upon therein. Similarly, internally generated industry forecasts, which we believe to be reliable based on our management’s knowledge of the industry, have not been independently verified by a third party.


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USE OF PROCEEDS
 
We estimate that the net proceeds from this offering will be approximately $      million, assuming an initial public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus, and after deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us.
 
A $1.00 increase or decrease in the assumed initial public offering price of $      per share would increase or decrease the net proceeds from this offering by approximately $      million, assuming that the number of shares offered by us, as set forth on the cover of this prospectus, remains the same and after deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us. If the underwriters exercise their option to purchase additional shares in full, we estimate that our net proceeds will be approximately $      million, assuming an initial public offering price of $      per share and after deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us.
 
We intend to use the net proceeds from this offering for seed production and commercialization expenses, research and development, capital expenditures, working capital and other general corporate purposes. We may also use a portion of the net proceeds to expand our business through acquisitions of other companies, assets or technologies. However, we do not have any present understandings, commitments or agreements to enter into any potential agreements for any acquisitions.
 
Some of the other principal purposes of this offering are to create a public market for our common stock, increase our visibility in the marketplace and provide liquidity to existing stockholders. Creating a public market for our common stock will facilitate our ability to raise additional equity in the future and to use our common stock as a means of attracting and retaining key employees and as consideration for acquisitions.
 
We will have broad discretion in the way that we use the net proceeds of this offering. The amounts that we actually spend for the purposes described above may vary significantly and will depend, in part, on the timing and amount of our future revenues, our future expenses and any potential acquisitions that we may propose. Pending the uses of the net proceeds of this offering, as described above, we intend to invest the net proceeds in short-term investment-grade, interest-bearing securities.


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DIVIDEND POLICY
 
We have never declared or paid cash dividends on our common or convertible preferred stock. We currently intend to retain any future earnings and do not expect to declare or pay any cash dividends in the foreseeable future. Any future determination to pay dividends will be at the discretion of our board of directors, subject to applicable laws, and will depend on our financial condition, results of operations, capital requirements, general business conditions and other factors that our board of directors considers relevant. Our existing loan agreement prohibits us from paying dividends on our capital stock.


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CAPITALIZATION
 
The following table sets forth our cash and cash equivalents and our capitalization as of February 28, 2011:
 
  •  on an actual basis;
 
  •  on a pro forma basis to give effect to:
 
(1) the filing of our amended and restated certificate of incorporation immediately prior to the completion of this offering;
 
(2) the automatic conversion of all outstanding shares of our convertible preferred stock into an aggregate of 46,059,819 shares of common stock immediately prior to the completion of this offering;
 
(3) the issuance of           shares of common stock immediately prior to the completion of this offering upon the net exercise of warrants outstanding to purchase shares of common stock issued to investors holding our Series F Warrants and our Series G Warrants, which would otherwise expire upon the completion of this offering, based upon an assumed initial public offering price of $      per share, the midpoint of the range set forth on the cover of this prospectus; and
 
(4) the reclassification of the convertible preferred stock warrant liability to stockholders’ (deficit) equity upon the completion of this offering; and
 
  •  on a pro forma as adjusted basis to reflect the pro forma adjustments described above and our receipt of the estimated net proceeds from this offering.
 
The pro forma and pro forma as adjusted information below is illustrative only and our capitalization following the completion of this offering will be adjusted based on the actual initial public offering price and other terms of this offering determined at pricing. You should read this table together with “Management’s Discussion and Analysis of Financial Condition and Results of


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Operations” and our consolidated financial statements and the accompanying notes appearing elsewhere in this prospectus.
 
                         
    As of February 28, 2011  
                Pro Forma as
 
   
Actual
   
Pro Forma
   
Adjusted(1)
 
    (Unaudited)  
    (In thousands, except per share data)  
 
Cash and cash equivalents
  $ 22,489     $ 22,489     $        
                         
Long-term debt, less current portion
  $ 3,109     $ 3,109     $    
Common and Preferred stock warrant liabilities
    8,997                
Convertible preferred stock, $0.01 par value; 50,854,383 authorized, 46,059,819 shares issued and outstanding, actual; no shares authorized, issued or outstanding, pro forma and pro forma as adjusted
    197,502                
                         
Stockholders’ (deficit) equity:
                       
Preferred Stock, $0.01 par value; no shares authorized, issued and outstanding, actual;           shares authorized, pro forma and pro forma as adjusted; no shares issued and outstanding, pro forma and pro forma as adjusted
                   
Common Stock, $0.01 par value; 75,000,000 shares authorized; 5,930,417 shares issued and outstanding, actual;           shares authorized, pro forma and pro forma as adjusted;          shares issued and outstanding, pro forma;          shares issued and outstanding pro forma as adjusted
    59       520          
Additional paid-in capital
    6,069       212,107          
Accumulated deficit
    (187,608 )     (187,608 )        
                         
Total stockholders’ (deficit) equity
    (181,480 )     25,019          
                         
Total capitalization
  $ 28,128     $ 28,128     $  
                         
 
(1) A $1.00 increase or decrease in the assumed initial public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus, would increase or decrease each of cash and cash equivalents, and total stockholders’ (deficit) equity by $     , assuming that the number of shares offered by us, as set forth on the cover of this prospectus, remains the same, and after deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us. Each increase of 1.0 million shares in the number of shares of common stock offered by us would increase each of cash and cash equivalents, and total stockholders’ (deficit) equity by $     , assuming an initial public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus. Similarly, each decrease of 1.0 million shares in the number of shares offered by us would decrease each of cash and cash equivalents, and total stockholders’ equity (deficit) by $     . If the underwriters’ option to purchase additional shares was exercised in full, pro forma as adjusted cash, cash equivalents, common stock and additional paid-in capital, stockholders’ equity (deficit), and shares issued and outstanding as of February 28, 2011, would be $      , $      , $      and          , respectively.
 
The table above does not include:
 
  •  7,192,391 shares of common stock issuable upon exercise of options to purchase our common stock outstanding as of February 28, 2011 at a weighted average exercise price of $1.62 per share;


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  •  600,000 shares of common stock issuable upon the exercise of warrants to purchase our common stock at a weighted average exercise price of $10.00 per share that do not expire on the completion of this offering;
 
  •  61,537 shares of common stock issuable upon exercise of warrants to purchase our preferred stock outstanding as of February 28, 2011 at a weighted average exercise price of $6.50 per share that do not expire on the completion of this offering; these preferred stock warrants will automatically convert to common stock warrants upon the completion of this offering;
 
  •  744,454 shares of common stock reserved as of February 28, 2011 for future issuance under our 2010 Stock Option/Stock Issuance Plan as more fully described in “Compensation Discussion and Analysis — Executive Compensation — Equity Compensation Plans”; and
 
  •            shares of common stock reserved for future issuance under our 2011 Equity Incentive Plan, which will become effective on the day prior to the day upon which we become subject to the reporting requirements of the Securities Exchange Act of 1934, as amended, or the Exchange Act.


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DILUTION
 
If you invest in our common stock in this offering, your ownership interest will be immediately diluted to the extent of the difference between the initial public offering price per share of our common stock and the net tangible book value per share of our common stock immediately after this offering. As of February 28, 2011, our pro forma net tangible book value was $      million, or $      per share of our common stock. Pro forma net tangible book value per share represents the amount of our total tangible assets less our total liabilities, divided by the total number of shares of our common stock outstanding, after giving effect to (i) the automatic conversion of all of our outstanding convertible preferred stock into shares of common stock upon the completion of this offering, (ii) the reclassification of preferred stock warrant liabilities to stockholders’ (deficit) equity immediately prior to the completion of this offering and (iii) the issuance of           shares of common stock immediately prior to the completion of this offering upon the net exercise of Series F warrants and Series G warrants, which would otherwise expire upon completion of this offering, based upon an assumed initial offering price of $      per share, the midpoint of the range set forth on the cover of this prospectus.
 
After giving effect to the above referenced adjustment and the sale by us of           shares of our common stock in this offering at an assumed initial public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus, and after deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us, our pro forma as adjusted net tangible book value as of February 28, 2011, would have been approximately $      million, or $      per share of our common stock. This amount represents an immediate increase in our pro forma as adjusted net tangible book value of $      per share to our existing stockholders and an immediate dilution of $      per share to new investors purchasing shares of our common stock in this offering at the initial public offering price.
 
The following table illustrates this dilution on a per share basis:
 
         
Assumed initial public offering price per share
  $        
Pro forma net tangible book value per share as of February 28, 2011, before giving effect to this offering
  $    
Increase in pro forma net tangible book value per share attributable to new investors purchasing shares in this offering
       
         
Pro forma as adjusted net tangible book value per share after giving effect to this offering
       
         
Dilution per share to investors in this offering
  $  
         
 
A $1.00 increase or decrease in the initial public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus, would increase or decrease our pro forma as adjusted net tangible book value per share after this offering by approximately $     and would increase or decrease dilution per share to new investors by approximately $      , assuming that the number of shares offered by us, as set forth on the cover of this prospectus, remains the same. In addition, to the extent any outstanding options or warrants are exercised, new investors will experience further dilution.
 
If the underwriters exercise their option to purchase additional shares in full, based upon an assumed initial public offering price of           per share, the midpoint of the range set forth on the cover of this prospectus, the pro forma as adjusted net tangible book value will increase to $      per share, representing an immediate increase to existing stockholders of $      per share and an immediate dilution of $      per share to new investors.
 
The following table summarizes, as of February 28, 2011, on a pro forma as adjusted basis, the number of shares purchased or to be purchased from us, the total consideration paid or to be paid to us, and the average price per share paid or to be paid to us by existing stockholders and new investors purchasing shares of our common stock in this offering at an assumed initial public offering


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price of $      per share, before deducting estimated underwriting discounts and commissions and estimated offering expenses payable by us. As the table below shows, new investors purchasing shares of our common stock in this offering will pay an average price per share substantially higher than our existing stockholders paid.
 
                                         
                            Average
 
    Share Purchased     Total Consideration     Price per
 
   
Number
   
Percent
   
Amount
   
Percent
   
Share
 
 
Existing stockholders
            %   $             %   $        
New investors
                                       
                                         
Total
                100 %   $         100 %        
                                         
 
A $1.00 increase or decrease or in the assumed initial public offering price of $      per share, the midpoint of the price range set forth on the cover of this prospectus, would increase or decrease the total consideration paid to us by new investors by $      million and increase or decrease or the percent of total consideration paid to us by new investors by     %, assuming that the number of shares offered by us, as set forth on the cover of this prospectus, remains the same.
 
The above discussion and tables are based on our common stock outstanding as of February 28, 2011, after giving effect to (i) the automatic conversion of all outstanding shares of our convertible preferred stock into an aggregate of 46,059,819 shares of common stock immediately prior to the completion of this offering and (ii) the issuance of          shares of common stock immediately prior to the completion of this offering upon the net exercise of Series F and Series G warrants, which would otherwise expire upon completion of this offering, based upon an assumed initial public offering price of $      per share, the midpoint range set forth on the cover of this prospectus.
 
This number excludes:
 
  •  7,192,391 shares of common stock issuable upon exercise of options to purchase our common stock outstanding as of February 28, 2011 at a weighted average exercise price of $1.62 per share;
 
  •  600,000 shares of common stock issuable upon exercise of warrants to purchase our common stock outstanding as of February 28, 2011 at a weighted average exercise price of $10.00 per share that do not expire on the completion of the initial public offering;
 
  •  61,537 shares of common stock issuable upon exercise of warrants to purchase our preferred stock outstanding as of February 28, 2011 at a weighted average exercise price of $6.50 per share that do not expire on the completion of this offering; these preferred stock warrants will automatically convert to common stock warrants upon the completion of this offering;
 
  •  744,454 shares of common stock reserved as of February 28, 2011 for future issuance under our 2010 Stock Option/Stock Issuance Plan as more fully described in “Compensation Discussion and Analysis — Executive Compensation — Equity Compensation Plans”; and
 
  •            shares of common stock reserved for future issuance under our 2011 Equity Incentive Plan, which will become effective on the day prior to the day upon which we become subject to the reporting requirements of the Securities Exchange Act of 1934, as amended, or the Exchange Act.
 
If all our outstanding stock options and warrants outstanding had been exercised as of February 28, 2011, our pro forma net tangible book value as of February 28, 2011, would have been approximately $      million or $      per share of our common stock, and the pro forma net tangible book value after giving effect to this offering would have been $      per share, representing dilution in our pro forma net tangible book value per share to new investors of $      .


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SELECTED CONSOLIDATED FINANCIAL DATA
 
In 2009, we changed our fiscal year end from December 31 to August 31. The change was effective for the eight-month period ended August 31, 2009. The selected consolidated statement of operations data for fiscal years ended December 31, 2007 and 2008, the eight months ended August 31, 2009 and the fiscal year ended August 31, 2010 and the selected consolidated balance sheet data at December 31, 2008, August 31, 2009 and 2010 are derived from our audited Consolidated Financial Statements, appearing elsewhere in this prospectus. The consolidated financial data for the six-month periods ended February 28, 2010 and 2011 have been derived from our unaudited consolidated financial statements included elsewhere in this prospectus. The unaudited consolidated financial statements have been prepared on a basis consistent with our audited consolidated financial statements and include, in the opinion of management, all adjustments, consisting only of normal and recurring adjustments, necessary for a fair presentation of such consolidated financial data. Results for interim periods are not necessarily indicative of results for a full fiscal year. The selected consolidated statement of operations data for the fiscal year ended December 31, 2006 and the selected consolidated balance sheet data as of December 31, 2006 have been derived from our audited consolidated financial statements, which are not included in this prospectus. Historical results are not necessarily indicative of results for future periods.
 
You should read the following selected consolidated financial data in conjunction with “Management’s Discussion Analysis of Financial Condition and Results of Operations” and our Consolidated Financial Statements appearing elsewhere in this prospectus.
 
                                                         
          Eight Months
          Six Months
 
          Ended
    Year Ended
    Ended
 
    Year Ended December 31,     August 31,     August 31,     February 28,  
   
2006
   
2007
   
2008
   
2009
   
2010
   
2010
   
2011
 
                                  (Unaudited)  
    (In thousands except share and per share data)  
 
Revenues
                                                       
Product sales
  $     $     $ 64     $ 98     $ 288     $ 5     $ 9  
Collaborative research and government grants
    26,643       7,180       3,880       2,328       6,326       2,497       3,320  
                                                         
Total revenue
    26,643       7,180       3,944       2,426       6,614       2,502       3,329  
                                                         
Cost and operating expenses
                                                       
Cost of product sales
                3,777       2,690       2,946       1,424       1,330  
Research and development
    18,101       19,220       20,309       12,397       16,697       8,516       8,641  
Selling, general and administrative
    8,079       9,811       8,784       6,645       9,207       4,237       4,339  
                                                         
Total cost and operating expenses
    26,180       29,031       32,870       21,732       28,850       14,177       14,310  
                                                         
Income (loss) from operations
    463       (21,851 )     (28,926 )     (19,306 )     (22,236 )     (11,675 )     (10,981 )
                                                         
Interest expense
    (204 )     (123 )           (5 )     (153 )     (3 )     (248 )
Interest income
    760       1,521       2,001       243       23       20       34  
Other income (expense)
    34       5             161       (152 )     (64 )     (85 )
                                                         
Income (loss) before income taxes
    1,053       (20,448 )     (26,925 )     (18,907 )     (22,518 )     (11,722 )     (11,280 )
Income tax benefit (expense)
    (1 )     (7 )     148       211       (65 )     (1 )     (1 )
                                                         
Net income (loss) before cumulative effect of a change in accounting principle
    1,052       (20,445 )     (26,777 )     (18,696 )     (22,583 )     (11,723 )     (11,281 )
                                                         
Cumulative effect of a change in accounting principle(1)
    649                                      
                                                         
Net income (loss)
    1,701       (20,445 )     (26,777 )     (18,696 )     (22,583 )     (11,723 )     (11,281 )
                                                         
Net income (loss) allocable to preferred stockholders
    (1,701 )                                    
                                                         
Net loss attributable to common stockholders
        $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
                                                         


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          Eight Months
          Six Months
 
          Ended
    Year Ended
    Ended
 
    Year Ended December 31,     August 31,     August 31,     February 28,  
   
2006
   
2007
   
2008
   
2009
   
2010
   
2010
   
2011
 
                                  (Unaudited)  
    (In thousands except share and per share data)  
 
Basic and diluted net loss per share attributable to common stockholders(2)
        $ (3.84 )   $ (4.89 )   $ (3.33 )   $ (3.90 )   $ (2.04 )   $ (1.91 )
Weighted average outstanding common shares used for net loss per share attributable to common stockholders(2):
                                                       
Basic and diluted
    5,112,258       5,323,259       5,473,090       5,621,671       5,791,443       5,751,539       5,900,947  
Pro forma net loss per share:
                                                       
Basic and diluted (unaudited)(3)
                                  $ (0.46 )           $ (0.22 )
                                                         
Weighted average outstanding common shares used in computing pro forma net loss per share(1):
                                                       
Basic and diluted (unaudited)(3)
                                    49,339,144               51,960,766  
                                                         
 
(1) Effective January 1, 2006 the Company changed the manner in which it accounted for certain warrants that were contingently redeemable.
(2) The basic and diluted loss per share are computed by dividing the net loss attributable to common stockholders by the weighted average number of common shares outstanding during the period. For the periods where we presented losses, all potentially dilutive common shares comprising of stock options, warrants and convertible preferred stock are anti-dilutive.
(3) The unaudited pro forma basic and diluted loss per common share have been computed as though the conversion had occurred as of September 1, 2009 to give effect to: (i) the automatic conversion of all outstanding shares of our convertible preferred stock into an aggregate of 46,059,819 shares of common stock effective immediately prior to the completion of this offering using the if-converted method, and (ii) the issuance of           shares of common stock immediately prior to the completion of this offering upon the net exercise of the Series F and G warrants, which would otherwise expire upon the completion of this offering, based upon an assumed initial public offering price of $           per share, the midpoint of the range set forth on the cover of this prospectus using the treasury stock method.
 
Our stock-based compensation expense is as follows (in thousands):
 
                                                         
                      Eight Months
                   
                      Ended
    Year Ended
    Six Months Ended
 
    Year Ended December 31,     August 31,
    August 31,
    February 28,  
   
2006
   
2007
   
2008
   
2009
   
2010
   
2010
   
2011
 
                                  (Unaudited)  
 
Research and development
    154       338       705       737       891       403       330  
Selling, general and administrative
    177       389       467       345       409       209       265  
                                                         
Total stock-based compensation expense
  $ 331     $ 727     $ 1,172     $ 1,082     $ 1,300     $ 612     $ 595  
                                                         
 
                                                 
                        As of
    As of December 31,   As of August 31,   February 28,
   
2006
 
2007
 
2008
 
2009
 
2010
 
2011
                        (Unaudited)
    (In thousands)
 
Consolidated Balance Sheet Data:
                                               
Cash and cash equivalents
  $ 4,661     $ 13,863     $ 12,145     $ 14,960     $ 33,055     $ 22,489  
Working capital
    15,773       70,029       41,297       27,543       28,325       17,560  
Total assets
    30,683       84,500       57,718       41,094       46,648       35,213  
Common and preferred stock warrant liabilities
    27       13       13       2,944       8,911       8,997  
Total long-term liabilities
    546       358       290       3,197       13,310       12,281  
Convertible preferred stock
    112,106       183,079       183,079       183,079       197,502       197,502  
Total stockholders’ deficit
  $ (87,181 )   $ (103,358 )   $ (128,905 )   $ (149,577 )   $ (170,829 )   $ (181,480 )

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MANAGEMENT’S DISCUSSION AND ANALYSIS
OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
 
The following discussion and analysis of our financial condition and results of operations should be read together with our consolidated financial statements and the other financial information appearing elsewhere in this prospectus. This discussion contains forward-looking statements that involve risks and uncertainties. Our actual results could differ materially from those anticipated in the forward-looking statements as a result of various factors, including those discussed below and those discussed in the section entitled “Risk Factors” included elsewhere in this prospectus.
 
Overview
 
We are an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks that can enable the large-scale replacement of petroleum and other fossil fuels. We use a combination of advanced plant breeding and biotechnology to develop new crops, known as dedicated energy crops, that we believe address the limitations of first-generation bioenergy feedstocks, such as corn and sugarcane, increase biomass productivity, reduce crop inputs and improve cultivation on marginal land.
 
Our first large-scale commercial products are proprietary sweet sorghum varieties that can be used as a “drop-in” feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills, the operating days of which are currently limited due to the inherent limitations of sugarcane physiology and growth patterns. Our dedicated energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Finally, baseload utility-scale electric power can also be generated from the biomass feedstocks grown from our seeds.
 
We operate in one segment, and accordingly, our results of operations are presented on a consolidated basis. During 2009, we changed our fiscal year-end to August 31 from December 31 to better match the seasonality of the production and selling cycles related to the seeds and traits business. Therefore our results of operations for the period ended August 31, 2009 reflect an eight-month period and are not comparable to the prior twelve-month period.
 
To date the majority of our revenue and expense has been denominated in U.S. dollars and foreign currency fluctuations have not had a significant impact on our historical results of operations. As we pursue and enter markets outside the United States, we expect our product sales will be made in local currencies and accordingly, that foreign currency fluctuations will have a greater impact on our operating results.
 
We generate our revenues from government grants, research and development collaboration agreements and from product sales. We began selling products in 2008 and, while our product sales have been minimal to date, we expect product sales to eventually become the primary source of our revenues. We expect product revenues to include a combination of seed sales and technology fees, similar to current business models used for food crops incorporating biotech traits. As we continue to develop traits for our products, we expect that a significant portion of our product revenues will be generated from the sale of seeds that include our traits. We believe our largest immediate market opportunity is selling sweet sorghum into the Brazilian biofuel market. Our longer term strategies involve capitalizing on the development of the emerging cellulosic biofuel and biopower markets in the United States and Europe.
 
We have formed collaborations with major participants in the bioenergy value chain to evaluate yields and other performance or conversion characteristics of our products and the logistics related to the use of our products. Our collaborators include ethanol mills, utilities, independent power producers, cellulosic biofuel companies, growers, grower cooperatives, equipment manufacturers, enzyme or fermentation technology companies and other support technology providers.


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In row crops, like corn, cotton and soybean, we have out-licensed a portion of our traits and gene technology and we continue to pursue opportunities to out-license these technologies in other crops. We have chosen to be a technology provider or trait provider in these markets and our collaborators and customers in this area consist primarily of multi-national seed companies.
 
We will market our seeds and traits directly to ethanol mills, utilities, independent power producers, cellulosic biofuel companies, individual growers and grower cooperatives and to date we have sold our seeds mainly to customers who are testing them in various technologies and environments. We also work with technology providers and other market participants such as equipment manufacturers and enzyme or fermentation technology companies, to encourage the use of our proprietary products. We market our products to biorefineries and biopower facilities, regardless of conversion technology, end-molecule or end-use. In Brazil, where we are completing commercial-scale trials with leading ethanol mills, we are marketing our sweet sorghum hybrid seeds for the 2011-2012 growing season. In the United States and Europe, we have launched the first energy crops seed brand, Blade Energy Crops, under which we market proprietary switchgrass varieties and high biomass sorghum hybrids to the emerging biomass market.
 
We have invested significantly in research, development and technology and applied our proprietary technology platforms to energy crops. To develop high performing seeds and traits, we have integrated a suite of advanced research and development methods, which include conventional breeding, marker-assisted breeding, genomics and biotechnology, along with large, proprietary collections of germplasm (the collections of genetic resources covering the diversity of a crop, the attributes of which are inherited from generation to generation). We have utilized our existing germplasm assets along with our research and development methods to create improved seeds and traits. As a result, we believe that we have one of the leading pipelines of proprietary crop traits, based on the number and nature of our traits as well as the two-species approach we employ to validate and successfully select gene-trait combinations. Our research and development investments have been significant, amounting to $19.2 million, $20.3 million, $12.4 million and $16.7 million in the years ended December 31, 2007 and December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, respectively, and $8.5 million and $8.6 million for the six months ended February 28, 2010 and 2011, respectively.
 
The remainder of our operating expenses are related to selling, general and administrative expenses incurred to establish and build our market presence and business infrastructure as well as seed production costs. For the periods prior to the commencement of sales of our seeds, we expensed our seed production costs as research and development. We began selling seeds in the United States in 2008, and since then, seed production costs have been computed on a first-in, first-out basis and valued at the lower of cost or market and are included as cost of product sales. Due to the early stage of commercialization of our seed products and lack of pricing data, a full valuation reserve has been recorded against our inventory value. Our sales and marketing expenses have not been significant to date but we expect such expenses to increase as we pursue, enter and expand our market opportunities.
 
Historically, we have funded our operations from the proceeds from equity sales, debt financing, payments from collaborators and government grants. We have experienced significant losses as we invested heavily in research and development, and those costs have exceeded revenues earned through collaboration agreements and government grants and were incurred prior to generating significant revenues through product sales. As of February 28, 2011, we had an accumulated deficit of $187.6 million. We incurred net losses of $20.5 million, $26.8 million, $18.7 million and $22.6 million in the years ended December 31, 2007 and December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, respectively, and $11.7 million and $11.3 million for the six months ended February 28, 2010 and 2011, respectively.


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Key Components of Our Results of Operations
 
Revenues
 
To date, our revenues have related to our product sales, collaborative research and government grants.
 
  •  Product Sales.  Product sales are primarily composed of sales of seeds. Going forward, we may include trait fees in our seed prices. We began selling products in 2008 and our product sales have been minimal to date.
 
  •  Collaborative Research.  Collaborative research revenues generally consist of payments for research and development activities for specific projects. These arrangements may include a combination of non-refundable technology license fees, research and development fees, and/or fees for the achievement of contractually defined milestone events and royalties.
 
  •  Government Grants.  Government grant revenues consist of payments from government entities. The terms of these grants generally provide us with reimbursement for research and development services and certain types of capital expenditures over a contractually defined period.
 
Cost of Product Sales
 
Cost of product sales consists principally of the cost of labor, raw materials and third-party services related to growing, harvesting, packaging and shipping our seeds. These costs are comprised of the direct costs of our seed production employees, as well as the temporary seasonal labor costs during planting and harvesting times. Third-party services include contract labor, grower payments, and other professional services related to the cost of product sales. Cost of product sales also consists of input costs such as chemicals and seed production costs. Costs associated with collaboration, research and government grants are not included in cost of product sales but instead are included as research and development expenses. Although historically not significant, future royalty expenses associated with collaboration and license agreements with third parties will be included in cost of product sales. The amount of royalties we owe under these agreements is a function of our sales and the applicable royalty rates depend on a number of factors, including the portion of our third-party collaborator’s intellectual property that is present in our products. We believe that as we develop our agronomic production operations, we will be able to achieve lower cost of product sales. To date, we have relied principally on third parties for the production of our sweet sorghum seed for use in Brazil. We believe that as we increase seed production volumes, we will be able to achieve better economies of scale from these third parties. In addition, we intend to produce more of our own seeds in Brazil, which will allow us to further decrease our costs. For our switchgrass and high biomass sorghum products, we are currently producing seeds at our own facility in Texas and believe that we will be able to decrease our costs over time by taking advantage of greater economies of scale.
 
Research and Development
 
Research and development expenses principally consist of personnel costs related to our research and development staff in support of exploratory research, breeding, agronomy and technology development and protection. Research and development expenses also include costs incurred for laboratory supplies, reimbursable costs associated with government grants and our collaborative agreements, third-party contract payments, consultants and facility and related overhead costs. We expect to increase our investments in research and development by hiring additional research and development staff. As such, we expect that our research and development expenses will increase in absolute dollars. As a percentage of revenue, we expect our research and development expenses to increase in the near-term and eventually stabilize. Also included in research and development expenses are expenses in connection with warrants granted to The Texas A&M University System and The Samuel Roberts Noble Foundation, Inc. The warrants vest based on the achievement of certain


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research and commercialization milestones or the passage of time. The warrants are accounted for at fair value and remeasured until the vesting targets are met.
 
Selling, General and Administrative
 
Selling, general and administrative expenses consist primarily of personnel costs related to our executive, sales, legal, finance, and human resources staff and professional fees including legal and accounting. Selling costs relate to business development and our sales and marketing programs to build brand awareness. We improve our brand awareness through programs including publication of crop management guides, speaking roles at industry events, trade show displays and local-level grower meetings. Costs related to these activities, including travel, are included in selling expenses. While we expect our selling expenses to increase in the near term, we believe that our focus on a relatively small number of customers, particularly in Brazil, where we plan to primarily market our products to mill operators, should allow us to operate with relatively modest overall selling expenses. We expect selling, general and administrative expenses to increase in absolute dollars in order to drive product sales and as we commence operations as a public company. Such increases may include increased insurance premiums, investor relations expenses, legal and accounting fees associated with the expansion of our business and corporate governance, financial reporting expenses, and expenses related to Sarbanes-Oxley and other regulatory compliance obligations. We expect to hire additional personnel, particularly in the area of general and administrative activities to support the growth of our business. As a percentage of revenue, we expect our selling, general and administrative expenses to increase in the near-term but to eventually decline.
 
Interest Expense
 
We recognize interest expense on notes payable and other debt obligations. We expect interest expense to fluctuate in the future with changes in our debt obligations.
 
Interest Income
 
Interest income consists primarily of interest earned on investments and cash balances. Our interest income will vary each reporting period depending on our average investment and cash balances during the period and market interest rates. We expect interest income to fluctuate in the future with changes in average investment and cash balances and market interest rates.
 
Other Income (Expense)
 
Other income (expense) consists primarily of the change in the fair value of our convertible preferred warrants and certain of our common stock warrants. Our preferred stock warrants and certain of our common stock warrants that expire upon the consummation of this offering are classified as liabilities. Our preferred stock warrants convert to equity classified common stock warrants upon the consummation of this offering. We expect the impact to our results of operations from our preferred stock and certain of our common stock warrant liabilities to be eliminated following our initial public offering.
 
Provision for Income Tax Benefits
 
Since our inception, we have been subject to income taxes principally in the United States, and Brazil where we recently established a legal presence. We anticipate that as we expand our operations outside the United States, we will become subject to taxation based on the foreign statutory rates and our effective tax rate could fluctuate accordingly.
 
Income taxes are computed using the asset and liability method, under which deferred tax assets and liabilities are determined based on the difference between the financial statement and tax bases of assets and liabilities using enacted tax rates in effect for the year in which the differences are expected to affect taxable income. Valuation allowances are established when necessary to reduce deferred tax assets to the amount expected to be realized.


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As of August 31, 2010 and February 28, 2011, based on the available information, it is more likely than not that our deferred tax assets will not be realized, and accordingly we have taken a full valuation allowance against all of our United States deferred tax assets. As of August 31, 2010, we had approximately $154.2 million of federal and $133.4 million of state operating loss carry-forwards available to offset future taxable income, which expire in varying amounts beginning in 2018 for federal and 2016 for state purposes if unused. Federal and state laws impose substantial restrictions on the utilization of net operating loss and tax credit carry-forwards in the event of an “ownership change”, as defined in Section 382 of the U.S. Internal Revenue Code of 1986, as amended, or the Internal Revenue Code. We have not completed a 382 analysis to determine if a change in ownership has occurred. Until an analysis is completed, there can be no assurance that the existing net operating loss carryforwards or credits are not subject to significant limitation.
 
Critical Accounting Policies and Estimates
 
Our discussion and analysis of our financial condition and results of operations is based upon our consolidated financial statements, which have been prepared in accordance with accounting principles generally accepted in the United States. The preparation of these consolidated financial statements requires us to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses and related disclosures. We base our estimates and assumptions on historical experience and on various other factors that we believe to be reasonable under the circumstances. We evaluate our estimates and assumptions on an ongoing basis. The results of our analysis form the basis for making assumptions about the carrying values of assets and liabilities that are not readily apparent from other sources. Our actual results may differ from these estimates under different assumptions or conditions.
 
We believe the following critical accounting policies involve significant areas of management’s judgments and estimates in the preparation of our financial statements.
 
Revenue Recognition
 
Revenues are recognized when the following criteria are met: (1) persuasive evidence of an arrangement exists; (2) transfer of product or technology has been completed or services have been rendered; (3) the fee is fixed or determinable; and (4) collectability is reasonably assured. To date, our primary source of revenues is derived from research collaborations and government grants. As our business continues to grow, we expect product sales will be our primary source of revenue.
 
Product Sales
 
Product sales are derived from sales of seeds and trait fees. Going forward, we may include trait fees in our seed prices. Product sales are recognized, net of discounts and allowances, once passage of title and risk of loss have occurred and contractually specified acceptance criteria have been met, provided all other revenue recognition criteria have also been met.
 
Collaborative Research and Government Grants
 
From time to time, we have entered into research and development collaboration agreements with third parties including a large agriculture supplier, consumer goods conglomerate and several biofuel producers. In addition, we have received grants from government agencies such as the Department of Energy and the United States Department of Agriculture. The research and development collaboration agreements typically provide us with multiple revenue streams, which may include upfront, non-refundable fees for licensing certain of our technologies, fees for research and development activities, and contingent milestone payments upon achievement of contractual criteria.
 
  •  Technology License Fees.  For collaboration agreements in which we have continuing involvement, license fees are recognized on a straight-line basis over the term of the arrangement. Licensing fees are non-refundable and not subject to future performance.


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  •  Government Grants.  We receive payments from government entities in the form of government grants. Government grants generally provide us with cost reimbursement for certain types of expenditures in return for research and development activities over a contractually defined period, as well as an allocated portion of our overhead expenses. Revenues from government grants are recognized in the period during which the related costs are incurred, provided that substantially all conditions under which the government grants were provided have been met and we only have perfunctory obligations outstanding.
 
  •  Research and Development Fees.  Generally, fees for research and development activities are recognized as the services are performed over the performance period, as specified in the respective agreements. Certain of our collaboration agreements require us to deliver research data by specific dates and that the collective program plan will result in reaching specific crop characteristics by certain dates. For such arrangements, we recognize revenues based on the approximate percentage of completion of services under the agreement, but the revenue recognized cannot exceed the payments that have accrued to us to date under the agreement. The research and development period is estimated at the inception of each agreement and is periodically evaluated.
 
  •  Milestone Payments.  Fees that are contingent upon achievement of substantive performance milestones at inception of the agreement are recognized based on the achievement of the milestone, as defined in the respective agreements.
 
We recognize deferred revenue to the extent that cash received under the collaboration agreement is in excess of the revenues recognized related to the agreement since the work under the agreement has not yet been performed at the time of cash receipt.
 
In April 2002, we entered into a multi-year discovery and development collaboration with Monsanto Company, focused on applying genomics technologies to identify genes that provide improvements in corn, soybean and certain row crops. Pursuant to this agreement, Monsanto licensed rights to a portion of our trait discovery pipeline in certain other row crops in exchange for license payments over several years. Monsanto also funded a research program with us. Substantially all of our revenues through December 31, 2007 were earned through this agreement. The research and collaboration portion of the agreement expired in April 2007. However, the license portion of the agreement entitles us to royalties for any products that Monsanto commercializes using our technology licensed under the agreement. In 2010, we and Monsanto agreed to amend the agreement. The amendment included an additional license fee pertaining to an expansion of the license grant. In connection with the collaboration agreement, Monsanto also purchased 3,333,333 shares of our Series E Preferred Stock.
 
In December 2007, we and a major consumer products company entered into a development and license agreement under which we are working to improve the yields of a food product. The agreement provided that we would receive $7.5 million in payments from this company over a five-year period provided milestones were met. In addition, the agreement provided that we would be entitled to receive a royalty based on the gross sales of crop varieties created under the agreement. We recognized revenue of zero, $1.0 million, $1.2 million and $1.9 million under this agreement in the years ended December 31, 2007 and December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, respectively. Revenue recognized under this agreement for the six months ended February 28, 2010 and 2011, was $0.9 million and $0.9 million, respectively.
 
We earn research funding revenues from several agreements with the Department of Energy, or the DOE, the USDA, and several leading biofuel producers whereby we perform research activities and receive revenues that partially reimburse our expenses incurred. Under such grants and agreements, we retain a proprietary interest in the products and technology we develop. These expense reimbursements primarily consist of direct expense sharing arrangements. We recorded revenue related to these grants of approximately $0.8 million, $2.0 million, $0.9 million and $2.8 million in the years ended December 31, 2007 and December 31, 2008, the eight months ended August 31,


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2009 and the year ended August 31, 2010, respectively, and $1.4 million and $1.5 million for the six months ended February 28, 2010 and 2011, respectively. The cumulative remaining amount to be claimed through September 2012 for all grants outstanding as of February 28, 2011 is approximately $5.7 million.
 
On December 16, 2008, we and a major agro-chemical company entered into a software license and collaboration agreement pursuant to which we provide software, software development and customer support for certain research application-based software. The agreement was structured into three phases and under the agreement, we are entitled to receive $1.5 million in payments over an approximate 4.5 year period. The software delivered is comprised of multiple elements, which include software, installation, training, customization of software, and software support. Software support is considered post-contract customer support, or PCS. We recognize revenues equal to the amount of expense recognized as services are rendered until the date that the PCS is the only undelivered element. Beginning on such date, the unrecognized revenue under the agreement will be recognized over the remaining PCS period. We recognized revenue and an equal amount of expenses totaling zero, $0.2 million and $0.3 million under this agreement in the year ended December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, respectively. Revenue and related costs recognized for the six months ended February 28, 2010 and 2011, were $0.1 million and $0.2 million, respectively.
 
Stock-based Compensation
 
We account for stock-based awards granted to employees and directors by recording compensation expense based on the awards’ grant date estimated fair values. Stock options or warrants granted to our non-employees are re-measured as they vest. The fair value and the resulting change in value, if any, is recognized in our consolidated statements of operations during the period the related services are rendered. We expect that our expense related to stock-based compensation will increase over time.
 
We estimate the fair value of our stock-based awards as of the date of grant using Black-Scholes option-pricing model. Determining the fair value of stock-based awards under this model requires judgment, including estimating the value per share of our common stock adjusted for our status as a private company, estimated volatility, expected term of the awards, estimated dividend yield and the risk-free interest rate. The assumptions used in calculating the fair value of stock-based awards represent our best estimates, based on management’s judgment and subjective future expectations. These estimates involve inherent uncertainties. If any of the assumptions used in the model change significantly, stock-based compensation recorded for future awards may differ materially from that recorded for awards granted previously.
 
The determination of the estimated value per share of our common stock is discussed below. We use the historical volatility of a group of comparative companies as an estimate for our estimated volatility. For purposes of determining the expected term of the awards in the absence of sufficient historical data relating to stock-option exercises for our company, we apply a simplified approach in which the expected term of an award is presumed to be the mid-point between the vesting date and the expiration date of the award. We base the risk-free rate used in the model on the United States Treasury zero coupon issues with remaining terms similar to the expected term of the stock options. Our estimated dividend yield is zero, as we have not and do not currently intend to declare dividends in the foreseeable future.
 
Once we have determined the estimated fair value of our employee stock-based awards, we recognize the portion of that value that corresponds to the portion of the award that is ultimately expected to vest, taking estimated forfeitures into account. This amount is recognized as an expense over the vesting period of the award using the straight-line method. We estimate forfeitures based upon our historical experience and, at each period, review the estimated forfeiture rate and make changes as factors affecting the forfeiture rate calculations and assumptions change.


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Information related to our stock-based compensation activity, including weighted average grant date fair values and associated Black-Scholes option-pricing model assumptions related to employee stock options, is as follows:
 
                                                 
            Eight Months
           
    Year Ended,
  Year Ended,
  Ended
  Year Ended
  Six Months Ended
    December 31,
  December 31,
  August 31,
  August 31,
  February 28,
   
2007
 
2008
 
2009
 
2010
 
2010
 
2011
                    (Unaudited)
 
Stock options granted (in thousands)
    1,471       996       94       972       251       876  
Weighted average exercise price
    $2.19       $2.25       $2.25       $2.25       $2.25       $2.43  
Weighted average grant date fair value per share of stock options granted
    $1.32       $1.59       $1.57       $1.51       $1.40       $1.61  
Weighted average Black-Scholes model assumptions:
                                               
Weighted average grant date fair value of common stock
    $2.11       $2.17       $2.16       $2.32       $2.17       $2.49  
Estimated volatility
    85 %     85 %     85 %     70 %     70 %     70 %
Estimated dividend yield
    0 %     0 %     0 %     0 %     0 %     0 %
Expected term (years)
    6.25       6.25       6.25       6.25       6.25       6.25  
Risk-free rates
    3.41%-5.15 %     1.92%-3.41 %     2.10%-3.18 %     2.29%-2.69 %     2.56%-2.69 %     1.48%-2.44 %
 
In 2006, we granted a warrant to purchase 400,000 shares of our common stock at an exercise price of $10 per share to The Samuel Roberts Noble Foundation. The warrant vests in four equal installments on each of May 2009, May 2011, May 2013 and May 2015 and will remain exercisable for a period of two years from the respective vesting date. These warrants are accounted for at fair value and re-measured until vested. The fair value, including the resulting change in value as a result of re-measurement is recognized as research and development expense.
 
In 2007, we granted a warrant to purchase 200,000 shares of our common stock at an exercise price of $10 per share to The Texas A&M University System. The warrant vests in various installments based on achievement of certain research and commercialization milestones and expires in August 2017. These warrants are accounted for at fair value and remeasured until the vesting targets are met. The fair value, including the resulting change in value as a result of re-measurement is recognized as research and development expense. No warrants had vested under this arrangement as of February 28, 2011.
 
Our stock-based compensation expense, including employee awards and non-employee stock options and equity classified warrants, is as follows (in thousands):
 
                                                 
                Eight Months
          Six Months
 
    Year Ended
    Ended
    Year Ended
    Ended
 
    December 31,     August 31,
    August 31,
    February 28,  
   
2007
   
2008
   
2009
   
2010
   
2010
   
2011
 
                            (Unaudited)  
 
Research and development
    338       705       737       891       403       330  
Selling, general and administrative
    389       467       345       409       209       265  
                                                 
Total stock-based compensation expense
  $ 727     $ 1,172     $ 1,082     $ 1,300     $ 612     $ 595  
                                                 


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Significant Factors, Assumptions and Methodologies Used in Determining Fair Value of Common Stock
 
We estimated the fair value of our common stock utilizing methodologies, approaches and assumptions consistent with the American Institute of Certified Public Accountants Practice Aid, “Valuation of Privately-Held-Company Equity Securities Issued as Compensation”, or the AICPA Practice Aid.
 
Given the absence of public market for our common stock, the fair values of our common stock underlying stock option grants were estimated by our board of directors, which intended all stock options granted to be exercisable at a price per share not less than the per share fair market value of our common stock underlying those options on the date of grant. To assist our board of directors in this determination and in order to set the exercise price of each stock option grant, our management informed them of the most recent available valuation analysis prior to the dates of grant.
 
In these valuations, we first estimated enterprise value and then allocated this value to the underlying classes of equity using the option-pricing method as outlined in the AICPA Practice Aid. In estimating the enterprise value, we used a combination of an income approach, which incorporated a discounted cash flow valuation, and a market approach. To allocate the enterprise value to the underlying classes of equity, the option-pricing method was used. This allocation was performed because the convertible preferred stockholders are entitled to certain preferences over common stockholders, including noncumulative dividends and liquidation preferences, which resulted in more of the enterprise value being allocated to the convertible preferred stockholders than common stockholders. The allocation model also considered time until liquidity event, risk-free rate, expected volatility and adjustment for the lack of marketability of our common stock.
 
The most recent valuations were performed as of December 31, 2008, August 31, 2009, August 31, 2010 and February 28, 2011. The valuations as of August 31, 2010 and February 28, 2011 were performed with the assistance of a third-party valuation firm. Prior to each grant date, the board of directors considered the most recent valuation along with other relevant objective and subjective factors it deemed important in each valuation, exercising significant judgment and reflecting the board of directors’ best estimates at the time. These factors included:
 
  •  the nature and history of our business;
 
  •  our operating and financial performance;
 
  •  general economic conditions and the specific outlook for our industry;
 
  •  the lack of liquidity for our common stock;
 
  •  the market price of companies engaged in the same or similar businesses with equity securities that are publicly traded;
 
  •  the differences between the terms of our preferred and common stock related to liquidation preferences, conversion rights, dividend rights, voting rights and other features; and
 
  •  the likelihood of achieving different liquidity events or remaining a private company.
 
We believe that we have used reasonable methodologies, approaches and assumptions in determining the fair value of our common stock. If we had made different assumptions and estimates, the amount of our recognized and to be recognized stock-based compensation expense could have been materially different.


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The table below sets forth information regarding stock options for grants between January 1, 2009 and February 28, 2011:
 
                                 
            Estimated
  Intrinsic
    Number of
  Exercise
  Fair Value of
  Value
Grants by month
 
Shares
 
Price
 
Common Stock
 
per Share
 
March 2009
    82,000     $ 2.25     $ 2.16        
June 2009
    12,000     $ 2.25     $ 2.16        
September 2009
    234,000     $ 2.25     $ 2.17        
December 2009
    17,000     $ 2.25     $ 2.24        
June 2010
    721,000     $ 2.25     $ 2.37     $ 0.12  
October 2010
    41,000     $ 2.25     $ 2.46     $ 0.21  
December 2010
    554,500     $ 2.44     $ 2.48     $ 0.04  
January 2011
    280,000     $ 2.44     $ 2.50     $ 0.06  
 
The table below sets forth the estimated fair value of our common stock at each valuation date since December 31, 2008:
 
         
    Estimated
    Fair Value of
Date
 
Common Stock
 
December 31, 2008
  $ 2.17  
August 31, 2009
  $ 2.16  
August 31, 2010
  $ 2.44  
February 28, 2011
  $ 2.52  
 
Valuation as of December 31, 2008
 
We estimated the fair market value of $2.17 per share of our common stock as of December 31, 2008 using an option-pricing method. We first estimated our enterprise value of $210 million and then allocated this value to the underlying classes of equity using the option-pricing method as outlined in the AICPA Practice Aid. In estimating the enterprise value, we used a combination of an income approach which incorporated a discounted cash flow valuation, and a market approach. To allocate the enterprise value to the underlying classes of equity, we used the option-pricing method. Within the allocation model, we estimated a time until liquidity event of 3 years, a risk-free rate of 1.34%, a volatility input of 85% and a 25% adjustment for the lack of marketability of our common stock.
 
Valuation as of August 31, 2009
 
We estimated the fair market value of $2.16 per share of our common stock as of August 31, 2009 using an option-pricing method. We first estimated our enterprise value of $209 million and then allocated this value to the underlying classes of equity. In estimating the enterprise value, we used a combination of an income approach, which incorporated a discounted cash flow valuation and a market approach. To allocate the enterprise value to the underlying classes of equity, we used the option-pricing method. Within the allocation model, we estimated a time until liquidity event of 3 years, a risk-free rate of 1.49% a volatility input of 85% and a 25% adjustment for the lack of marketability of our common stock.
 
Valuation as of August 31, 2010
 
We obtained the assistance of a third-party valuation firm in estimating the fair market value of our common stock as of August 31, 2010 using an option-pricing method. We first estimated our enterprise value of $264 million and then used the option-pricing method to allocate the estimated enterprise value between common and preferred stockholders. In estimating the enterprise value, we used a combination of an income approach, which incorporated a discounted cash flow valuation and


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a market approach. Within the allocation model, we used a volatility input of 70% based on the historically observed volatilities of selected public guideline companies and estimated a time until liquidity event of 3 years. Applying an appropriate risk free interest rate of 0.72% and a 25% adjustment for the lack of marketability of our common stock, we estimated a fair market value at August 31, 2010 of $2.44 per share of our common stock.
 
Valuation as of February 28, 2011
 
We obtained the assistance of a third-party valuation firm in estimating the fair market value of $2.52 per share of our common stock as of February 28, 2011 using an option-pricing method. We first estimated our enterprise value of $270 million and then allocated this value between common and preferred stockholders using the option-pricing method. In estimating the enterprise value, we used a combination of an income approach, which incorporated a discounted cash flow valuation and a market approach. Within the allocation model, we estimated a time until liquidity event of 2.5 years, a risk-free rate of 0.94% a volatility input of 70% based on the historically observed volatilities of selected public guideline companies, and a 25% adjustment for the lack of marketability of our common stock.
 
As of February 28, 2011 the date of our most recent valuation, we were considering a variety of financing alternatives, including financing from existing investors, debt financing and an initial public offering. As of February 28, 2011, an initial public offering was not anticipated in the near term. In April 2011, our board of directors approved plans to move forward with an initial public offering of our common stock. This determination was based in part on macroeconomic events and the anticipated success of our Brazilian seed trials scheduled for May 2011. We view the successful completion of our seed trials in Brazil as a significant value driving event and as such, we reasonably expect our enterprise value and common stock value to increase from the most recent valuation as of February 28, 2011.
 
Fair Value of Warrants
 
Liability Classified Warrants to Purchase Common Stock
 
We issued warrants to purchase our common stock in connection with the issuances of our Series F and Series G preferred stock. We have accounted for these warrants as liabilities as the warrants are not considered indexed to our common stock. We estimate the fair value of our liability classified warrants to purchase common stock using an option-pricing model, which incorporates several estimates and assumptions that are subject to significant management judgment. Changes in fair value at each period-end are recorded in other income (expense) in our consolidated statement of operations until the earlier of the exercise or expiration of the warrants, or the completion of this offering.
 
Upon the completion of this offering, these warrants to purchase common stock will either expire or be exercised for shares of common stock, and at that time, we will no longer record any changes in the fair value of these liabilities in our consolidated statement of operations.
 
Warrants to purchase the following shares of common stock were outstanding as follows:
 
                                                 
    As of
  As of
  As of
  As of
  As of
   
    December 31,
  August 31,
  August 31,
  February 28,
  February 28,
  Exercise
Series
 
2008
 
2009
 
2010
 
2010
 
2011
 
Price
                (Unaudited)    
 
Series F
    2,307,697       2,307,697       2,307,697       2,307,697       2,307,697     $ 6.50  
Series G
                3,076,923             3,076,923     $ 6.50  


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The fair value of the Series F warrants was calculated using the following assumptions:
 
                 
    As of
  As of
    August 31,   February 28,
   
2009
 
2010
 
2010
 
2011
            (Unaudited)
 
Expected term (in years)
  6.0   5.0   5.5   4.5
Expected volatility
  90%   90%   90%   90%
Risk free interest rate
  3.21%   1.47%   2.36%   2.13%
Expected dividend yield
  0%   0%   0%   0%
Estimated fair value (in thousands)
  $2,931   $2,994   $2,995   $2,945
 
The fair value of the Series G warrants was calculated using the following assumptions:
 
         
    As of
  As of
    August 31,   February 28,
   
2010
 
2011
        (Unaudited)
 
Expected term (in years)
  9.8   9.3
Expected volatility
  85%   85%
Risk free interest rate
  2.70%   3.42%
Expected dividend yield
  0%   0%
Estimated fair value (in thousands)
  $5,584   $5,721
 
Liability Classified Warrants to Purchase Convertible Preferred Stock
 
We have issued warrants to purchase our convertible preferred stock in connection with certain financing arrangements. We have accounted for these warrants as liabilities because the underlying shares of convertible preferred stock are redeemable in the case of a deemed liquidation. We estimate the fair value of our convertible preferred stock warrants using an option-pricing model, which incorporates several estimates and assumptions that are subject to significant management judgment. Changes in fair value at each period end are recorded in other income (expense) in our consolidated statement of operations until the earlier of the exercise or expiration of the warrants, or the completion of this offering.
 
Upon the completion of this offering, our warrants to purchase convertible preferred stock will convert to warrants to purchase common stock, and at that time, we will no longer record any changes in the fair value of these liabilities in our statement of operations.
 
Seed Inventory
 
Seed inventory costs are computed on a first-in, first-out basis and valued at the lower of cost or market and are included as cost of product sales. Due to the early stage of commercialization of our seed products and with no established market for our seed products, a full valuation reserve has been recorded against our inventory.
 
Income Taxes
 
Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. We


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record a valuation allowance when it is more likely than not that some of our net deferred tax assets will not be realized. In determining the need for valuation allowances, we consider our projected future taxable income and the availability of tax planning strategies. We have recorded a full valuation allowance to reduce our net deferred tax assets to zero except to the extent of federal credits refundable in 2009 because we have determined that it is not more likely than not that any of our net deferred tax assets will be realized. If in the future we determine that we will be able to realize any of our net deferred tax assets, we will make an adjustment to the allowance, which would increase our income in the period that the determination is made.
 
We operate in various tax jurisdictions and are subject to audit by various tax authorities. We recognize the effect of income tax positions only if those positions are more likely than not of being sustained. Recognized income tax positions are measured at the largest amount that is greater than 50% likely of being realized. Changes in recognition or measurement are reflected in the period in which the change in judgment occurs.
 
Impairment of Long-Lived Assets
 
Long-lived assets, such as property and equipment, are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. Our long-lived assets comprise a single asset group for evaluation purposes. We evaluate whether an impairment indicator occurs primarily based on progress achieved against our business plans. To the extent that an impairment indicator has occurred, recoverability of assets to be held and used is measured by a comparison of the carrying amount of an asset to estimated undiscounted future cash flows expected to be generated by the asset. If the carrying amount of an asset exceeds its estimated undiscounted future cash flows, an impairment charge is recognized in the amount by which the carrying amount of the asset exceeds the fair value of the asset. For all periods presented herein, no impairment indicators have occurred and therefore no impairment charges have been recognized.


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Results of Operations
 
The following table sets forth our consolidated results of operations for the periods shown:
 
                                                 
                            Six Months
 
                Eight Months
          Ended
 
    Year Ended
    Ended
    Year Ended
    February 28
 
    December 31,     August 31,
    August 31,
    (Unaudited),  
   
2007
   
2008
   
2009
   
2010
   
2010
   
2011
 
    (In thousands)  
 
Revenues
                                               
Product sales
  $     $ 64     $ 98     $ 288     $ 5     $ 9  
Collaborative research and government grants
    7,180       3,880       2,328       6,326       2,497       3,320  
                                                 
Total revenue
    7,180       3,944       2,426       6,614       2,502       3,329  
                                                 
Cost and operating expenses
                                               
Cost of product sales
          3,777       2,690       2,946       1,424       1,330  
Research and development
    19,220       20,309       12,397       16,697       8,516       8,641  
Selling, general and administrative
    9,811       8,784       6,645       9,207       4,237       4,339  
                                                 
Total cost and operating expenses
    29,031       32,870       21,732       28,850       14,177       14,310  
                                                 
Loss from operations
    (21,851 )     (28,926 )     (19,306 )     (22,236 )     (11,675 )     (10,981 )
Interest expense
    (123 )           (5 )     (153 )     (3 )     (248 )
Interest income
    1,521       2,001       243       23       20       34  
Other income (expense)
    5             161       (152 )     (64 )     (85 )
                                                 
Loss before income taxes
    (20,448 )     (26,925 )     (18,907 )     (22,518 )     (11,722 )     (11,280 )
Income tax benefit (expense)
    (7 )     148       211       (65 )     (1 )     (1 )
                                                 
Net loss
  $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
                                                 
 
Comparison of Six Months Ended February 28, 2010 and 2011
 
Revenues
 
                         
    Six Months Ended
       
    February 28 (Unaudited),        
   
2010
   
2011
   
Change
 
    (In thousands)  
 
Product sales
  $ 5     $ 9     $ 4  
Collaborative research and government grants
    2,497       3,320       823  
                         
Total revenue
  $ 2,502     $ 3,329     $ 827  
                         


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Our total revenues increased by $0.8 million to $3.3 million in the six months ended February 28, 2011 compared to the same period in the prior year. The increase was primarily the result of an increase of $0.6 million and $0.4 million in billings, respectively, related to a collaboration agreement and one of our new government grants with ARPA-E.
 
Cost and Operating Expenses
 
                         
    Six Months
       
    Ended
       
    February 28 (Unaudited),        
   
2010
   
2011
   
Change
 
    (In thousands)  
 
Cost of product sales
  $ 1,424     $ 1,330     $ (94 )
Research and development
    8,516       8,641       125  
Selling, general and administrative
    4,237       4,339       102  
                         
Total cost and operating expenses
  $ 14,177     $ 14,310     $ 133  
                         
 
Cost of Product Sales
 
Our cost of product sales decreased by $0.1 million to $1.3 million in the six months ended February 28, 2011 compared to the six months ended February 28, 2010. The cost of product sales was relatively unchanged for the comparative periods. During the 2011 period, we decreased our production and related costs of production for our switchgrass product as we determined we had produced adequate supply to meet existing demand at that time. This cost reduction was partially offset by higher production costs associated with increased production of our sweet sorghum and high biomass sorghum products.
 
Research and Development Expenses
 
Our research and development expense increased by $0.1 million for the six months ended February 28, 2011 compared to the six months ended February 28, 2010. The focus of our research and development spending varies year over year. During the 2011 period, we increased our spending associated with our breeding and trait development and agronomy programs by $0.2 million, which was almost entirely offset by lower spending on exploratory research on potential traits of $0.2 million.
 
Selling, General and Administrative Expenses
 
Our selling, general and administrative expenses remained relatively flat, increasing by $0.1 million to $4.3 million in the six months ended February 28, 2011 compared to the same period in the prior year. There was an increase in selling, general and administrative expense related to increased administrative and marketing support for the commencement of our commercial trials for sweet sorghum in Brazil.


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Interest Expense, Interest Income and Other Income (Expense)
 
                         
    Six Months Ended
       
    February 28 (Unaudited),        
   
2010
   
2011
   
Change
 
    (In thousands)  
 
Interest expense
  $ (3 )   $ (248 )   $ (245 )
Interest income
    20       34       14  
Other income (expense)
    (64 )     (85 )     (21 )
                         
Total
  $ (47 )   $ (299 )   $ (252 )
                         
 
Interest expense, interest income and other income (expense) increased by $0.3 million in the six months ended February 28, 2011 compared to the same period in the prior year. The increase was primarily the result of higher interest expense.
 
Interest Expense
 
Interest expense increased by $0.2 million in the six months ended February 28, 2011 compared to the same period in the prior year. The increase was primarily related to borrowings in February and August 2010 under our new Loan and Security Agreement with a commercial bank.
 
Interest Income
 
Interest income increased by $14,000 in the six months ended February 28, 2011 compared to the same period in the prior year. The increase was primarily the result of higher average cash invested balances.
 
Other Income (Expense)
 
Other income (expense) increased by $21,000 to $85,000 for the six months ended February 28, 2011 compared to $64,000 for the six months ended February 28, 2010. The increase is primarily the result of the fair value changes associated with our warrant valuations.
 
Comparison of Eight Months Ended August 31, 2009 and Year Ended August 31, 2010
 
During 2009 we changed our fiscal year-end from December 31 to August 31 for financial reporting purposes. The change was effective for the eight-month period ended August 31, 2009. The discussion below compares the eight months ended August 31, 2009 to the twelve months ended August 31, 2010.
 
Revenues
 
                         
    Eight Months
             
    Ended
    Year Ended
       
    August 31,
    August 31,
       
   
2009
   
2010
   
Change
 
    (In thousands)  
 
Product sales
  $ 98     $ 288     $ 190  
Collaborative research and government grants
    2,328       6,326       3,998  
                         
Total revenue
  $ 2,426     $ 6,614     $ 4,188  
                         


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Our total revenues increased by $4.2 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. While the increase was largely due to non-comparable periods (twelve months in 2010 as compared to eight months in 2009), the period-to-period increase was also due to higher billings related to our collaborative research agreements and an increase in revenue for our grants including the two new government grants from USAID and ARPA-E, which in the aggregate contributed $1.7 million to the 2010 period.
 
Cost and Operating Expenses
 
                         
    Eight Months
             
    Ended
    Year Ended
       
    August 31,
    August 31,
       
   
2009
   
2010
   
Change
 
    (In thousands)  
 
Cost of product sales
  $ 2,690     $ 2,946     $ 256  
Research and development
    12,397       16,697       4,300  
Selling, general and administrative
    6,645       9,207       2,562  
                         
Total cost and operating expenses
  $ 21,732     $ 28,850     $ 7,118  
                         
 
Cost of Product Sales
 
Our cost of product sales increased by $0.3 million to $2.9 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. The increase was partially due to non-comparable periods (twelve months in 2010 as compared to eight months in 2009). In addition, we decreased our production and related costs of production for our switchgrass as we determined we had produced adequate supply to meet existing demand at that time. This cost reduction was offset by higher production costs associated with our high biomass sorghum products in the United States.
 
Research and Development Expenses
 
Our research and development expenses increased by $4.3 million to $16.7 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. The increase was largely due to non-comparable periods (twelve months in 2010 as compared to eight months in 2009). In addition, during fiscal 2010, we increased our spending from $6.8 million to $9.9 million for trait development and plant breeding at our facility located near College Station, Texas and for our agronomy research at multiple locations in the United States.
 
Selling, General and Administrative Expenses
 
Our selling, general and administrative expenses increased by $2.6 million to $9.2 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. While the increase was largely due to non-comparable periods (twelve months in 2010 as compared to eight months in 2009), the period-to-period increase was partially due to increased spending related to the start up of our operations in Brazil, and also increased administrative costs in support of our research and operations in Texas.


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Interest Expense, Interest Income and Other Income (Expense)
 
                         
    Eight Months
             
    Ended
    Year Ended
       
    August 31,
    August 31,
       
   
2009
   
2010
   
Change
 
    (In thousands)  
 
Interest expense
  $ (5 )   $ (153 )   $ (148 )
Interest income
    243       23       (220 )
Other income (expense)
    161       (152 )     (313 )
                         
Total
  $ 399     $ (282 )   $ (681 )
                         
 
Interest Expense, Interest Income and Other Income (Expense) decreased by $0.7 million to $(0.3) million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. The decrease in dollars was largely due to non-comparable periods (twelve months in 2010 as compared to eight months in 2009) and an increase in fair value of our warrants, a decrease in interest income from cash investments, and an increase in interest expense related to our debt financing during 2010.
 
Interest Expense
 
Interest expense increased by $0.1 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. While the increase was partially due to non-comparable periods (twelve months in 2010 as compared to eight months in 2009), the period-to-period increase was primarily due to the higher outstanding principal balances on our bank debt in 2010 compared to 2009.
 
Interest Income
 
Interest income decreased by $0.2 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. The decrease in interest income was primarily due to a more conservative investment of available cash.
 
Other Income (Expense)
 
Other income (expense) decreased by $0.3 million in the year ended August 31, 2010 compared to the eight months ended August 31, 2009. The decrease was primarily due to higher expense related to the increase in the fair value of our warrants in fiscal 2010.
 
Comparison of Year Ended December 31, 2008 and Eight Months Ended August 31, 2009
 
During 2009 we changed our fiscal year-end from December 31 to August 31 for financial reporting purposes. The change was effective for the eight-month period ended August 31, 2009. The discussion below compares the year ended December 31, 2008 to the eight months ended August 31, 2009.


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Revenues
 
                         
          Eight Months
       
    Year Ended
    Ended
       
    December 31,
    August 31,
       
   
2008
   
2009
   
Change
 
    (In thousands)  
 
Product sales
  $ 64     $ 98     $ 34  
Collaborative research and government grants
    3,880       2,328       (1,552 )
                         
Total revenue
  $ 3,944     $ 2,426     $ (1,518 )
                         
 
Our total revenues decreased by $1.5 million to $2.4 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. While the decrease was largely due to non-comparable periods (eight months in 2009 as compared to twelve months in 2008), the period-to-period decrease was also due to lower billings related to the completion of one of our grants, which represented $0.2 million in fiscal 2008.
 
Cost and Operating Expenses
 
                         
          Eight Months
       
    Year Ended
    Ended
       
    December 31,
    August 31,
       
   
2008
   
2009
   
Change
 
    (In thousands)  
 
Cost of product sales
  $ 3,777     $ 2,690     $ (1,087 )
Research and development
    20,309       12,397       (7,912 )
Selling, general and administrative
    8,784       6,645       (2,139 )
                         
Total cost and operating expenses
  $ 32,870     $ 21,732     $ (11,138 )
                         
 
Cost of Product Sales
 
Our cost of product sales decreased by $1.1 million to $2.7 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. While the decrease was largely due to non-comparable periods (eight months in 2009 as compared to twelve months in 2008), the period-to-period decrease was partially offset by higher operating costs related to the operations of our seed facility located in Amarillo, Texas during the eight months ended August 31, 2009.
 
Research and Development Expenses
 
Our research and development expenses decreased by $7.9 million to $12.4 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. The decrease in dollars was largely due to non-comparable periods (eight months in 2009 as compared to twelve months in 2008) and as a result of a $1.1 million reduction in personnel and related activities as we transitioned our efforts from exploratory trait research to agronomy, plant breeding and field research in support of our transition to a commercial seed business.
 
Selling, General and Administrative Expenses
 
Our selling, general and administrative expenses decreased by $2.1 million to $6.6 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. The lower selling, general and administrative expenses were due to non-comparable periods (eight months in 2009 as compared to twelve months in 2008).


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Interest Expense, Interest Income and Other Income (Expense)
 
                         
          Eight Months
       
    Year Ended
    Ended
       
    December 31,
    August 31,
       
   
2008
   
2009
   
Change
 
    (In thousands)  
 
Interest expense
  $     $ (5 )   $ (5 )
Interest income
    2,001       243       (1,758 )
Other income
          161       161  
                         
Total
  $ 2,001     $ 399     $ (1,602 )
                         
 
Interest Expense, Interest Income and Other Income (Expense), decreased by $1.6 million to $0.4 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. The decrease in dollars was largely due to non-comparable periods (eight months in 2009 as compared to twelve months in 2008) and the reduction of interest income earned on investments.
 
Interest Expense
 
Interest expense increased by $5,000 in the eight months ended August 31, 2009 compared to the year ended December 31, 2008.
 
Interest Income
 
Interest income decreased by $1.8 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. The decrease in dollars was primarily due to a more conservative investment of available cash.
 
Other Income
 
Other income increased by $0.2 million in the eight months ended August 31, 2009 compared to the year ended December 31, 2008. The increase was due to the change in the fair value of our warrants in fiscal 2008.
 
Comparison of Years Ended December 31, 2007 and 2008
 
Revenues
 
                         
    Year Ended
    Year Ended
       
    December 31,
    December 31,
       
   
2007
   
2008
   
Change
 
    (In thousands)  
 
Product sales
  $     $ 64     $ 64  
Collaborative research and government grants
    7,180       3,880       (3,300 )
                         
Total revenue
  $ 7,180     $ 3,944     $ (3,236 )
                         
 
Our total revenues decreased by $3.2 million to $3.9 million in the year ended December 31, 2008 compared to the year ended December 31, 2007. The decrease was primarily the result of the completion of a discovery and development collaboration agreement which represented $6.3 million in revenue in 2007, and was partially offset by increased revenues of $2.1 million related to two of our other collaborative agreements along with increased billings for our government grants.


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Cost and Operating Expenses
 
                         
    Year Ended
    Year Ended
       
    December 31,
    December 31,
       
   
2007
   
2008
   
Change
 
    (In thousands)  
 
Cost of product sales
  $     $ 3,777     $ 3,777  
Research and development
    19,220       20,309       1,089  
Selling, general and administrative
    9,811       8,784       (1,027 )
                         
Total cost and operating expenses
  $ 29,031     $ 32,870     $ 3,839  
                         
 
Cost of Product Sales
 
Our cost of product sales increased to $3.8 million in the year ended December 31, 2008 compared to the same period in the prior year. This increase was largely a result of commencing commercial seed production activity, primarily in the United States, for switchgrass in 2008. Prior to January 1, 2008, we had not commenced commercial seed production.
 
Research and Development Expenses
 
Our research and development expenses increased by $1.1 million in the year ended December 31, 2008 compared to the same period in the prior year. This increase was primarily the result of increased research payments to third parties for field trials and related expenses in the U.S. for switchgrass and high biomass sorghum.
 
Selling, General and Administrative Expenses
 
Our selling, general and administrative expenses decreased by $1.0 million to $8.8 million in the year ended December 31, 2008 compared to the same period in the prior year. The decrease was primarily the result of a reduction in patent expenses and legal and professional fees of $1.4 million, partially offset by an increase in personnel costs of $0.3 million.
 
Interest Expense, Interest Income and Other Income (Expense)
 
                         
    Year Ended
    Year Ended
       
    December 31,
    December 31,
       
   
2007
   
2008
   
Change
 
    (In thousands)  
 
Interest expense
  $ (123 )   $     $ 123  
Interest income
    1,521       2,001       480  
Other income (expense)
    5             (5 )
                         
Total
  $ 1,403     $ 2,001     $ 598  
                         
 
Interest expense, interest income and other income (expense), increased by $0.6 million to $2.0 million in the year ended December 31, 2008 compared to the same period in the prior year. The increase was the result of an increase in interest income of $0.5 million from higher invested cash balances and a decrease in interest expense of $0.1 million from the reduction in debt and associated interest cost.
 
Interest Expense
 
Interest expense decreased by $0.1 million for the year ended December 31, 2008 as all debt and related interest expense obligations were repaid during the year ended December 31, 2007.


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Interest Income
 
Interest income increased by $0.5 million to $2.0 million in the year ended December 31, 2008 compared to the same period in the prior year. This increase was a result of increased levels of invested cash for the year ended December 31, 2008.
 
Other Income (Expense)
 
Other income (expense) remained relatively flat, decreasing by $5,000 in the year ended December 31, 2008 compared to the same period in the prior year.
 
Liquidity and Capital Resources
 
Since inception, we have funded our operations through the sale of preferred stock and warrants, collaborative research and government grant revenues, and borrowings under financing arrangements. As of February 28, 2011, our cash and cash equivalents totaled $22.5 million.
 
Since our inception, we have incurred significant net losses, and, as of February 28, 2011, we had an accumulated deficit of $187.6 million. We expect to incur additional losses related to the continued development and expansion of our business including research and development, seed production and operations, and sales and marketing. There is also no assurance that profitable operations will be achieved, or if achieved, can be sustained on a continued basis.
 
In 2010, we entered into a Loan and Security Agreement, or the Loan Agreement, with a commercial bank. The Loan Agreement provides financing for qualified equipment purchases. We borrowed a total of $7.0 million in two tranches at interest rates of Bank Prime plus 2.75% (6.0% as of February 28, 2011). Monthly principal repayments on the first tranche are $75,000 per month through the maturity date of June 2013. Monthly principal repayments on the second tranche total $111,000 per month through the maturity date of August 2013. Currently, we make monthly principal payments of approximately $186,000 and interest payments of approximately $27,000 per month based on the 6.0% borrowing rate. The Loan Agreement is secured by certain of our assets, excluding intellectual property. The Loan Agreement requires compliance with covenants that require certain reporting obligations, the maintenance of $3.0 million in restricted cash and a minimum quick ratio, which is a ratio of certain current assets to current liabilities. At February 28, 2011, we were in compliance with the Loan Agreement debt covenants.
 
We believe that our existing cash and cash equivalents and the net proceeds of this offering will provide adequate resources to fund our operations, including research and development expenses, planned capital expenditures and working capital requirements for at least the next 18 months. In order to fund our operations beyond that time, we may need to raise additional funds through the issuance of equity, equity-related or debt securities or through obtaining credit from government or financial institutions. We cannot be certain that additional funds will be available to us on favorable terms when required, or at all.
 
Capital Expenditures
 
For the year ended December 31, 2007, the year ended December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, we used $2.3 million, $3.8 million, $1.6 million and $2.1 million, respectively, in cash to fund capital expenditures. For the six months ended February 28, 2010 and 2011, we used $1.3 million and $0.2 million to fund capital expenditures. We currently anticipate that our aggregate capital expenditures will be between $0.3 million and $0.5 million through the year ended August 31, 2011, which will primarily relate to agronomy and breeding. We currently anticipate making aggregate capital expenditures between $1.1 million and $2.5 million for the year ended August 31, 2012.


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The following table sets forth a summary of our cash flows for the periods indicated:
 
                                                 
            Eight Months
      Six Months Ended
            Ended
  Year Ended
  February 28,
    Year Ended December 31,   August 31,
  August 31,
  (Unaudited)
   
2007
 
2008
 
2009
 
2010
 
2010
 
2011
            (In thousands)        
 
Net cash used in operating
activities
  $ (10,032 )   $ (24,899 )   $ (13,508 )   $ (18,846 )   $ (10,276 )   $ (9,272 )
Net cash (used in) provided by investing activities
    (53,817 )     23,433       16,329       10,372       12,553       (204 )
Net cash provided by (used in) financing activities
    73,050       (252 )     (6 )     26,569       3,015       (1,090 )
 
Cash Flows from Operating Activities
 
For all periods presented, we have incurred net losses and net cash used in operating activities. The net cash used in operating activities primarily resulted from significant research and development expenses and seed production costs to develop and produce our improved seeds and traits. Such expenses and costs have exceeded our revenues, which have primarily been generated from collaborative research and government grants and, to a much lesser extent, product sales.
 
Net cash outflows of $9.3 million from operating activities during the six months ended February 28, 2011 primarily resulted from our net loss of $11.3 million, which included non-cash items, including $1.1 million in depreciation expense and $0.6 million in stock-based compensation expense.
 
Net cash outflows of $10.3 million from operating activities during the six months ended February 28, 2010 primarily resulted from our net loss of $11.7 million, a decrease of $0.8 million in accounts payable and accrued expenses and increase of $0.9 million in deferred revenue. The net loss of $11.7 million also included non-cash items, including $1.2 million in depreciation expense and $0.6 million in stock-based compensation expense.
 
Net cash outflows of $18.8 million from operating activities during the year ended August 31, 2010 primarily resulted from our net loss of $22.6 million, an increase in accounts receivables of $0.7 million and a decrease in accounts payable and accrued expenses of $0.3 million. These uses of cash were partially offset by non-cash items, including $2.4 million in depreciation expense and $1.3 million in stock-based compensation expense, and a $0.4 million increase in deferred revenue.
 
Net cash outflows of $13.5 million from operating activities during the eight months ended August 31, 2009 primarily resulted from our net loss of $18.7 million which included non-cash items of $1.5 million in depreciation expense and $1.1 million in stock-based compensation expense. These cash outflows were partially offset by a decrease of $1.3 million in accounts receivable and an increase of $0.9 million in accounts payable and accrued expenses.
 
Net cash outflows of $24.9 million from operating activities during the year ended December 31, 2008 primarily resulted from our net loss of $26.8 million, an increase in accounts receivables of $1.5 million, and a decrease in accounts payable and accrued expenses of $0.8 million. These uses of cash were partially offset by non-cash items, including $2.2 million in depreciation expense and $1.2 million in stock-based compensation expense, and a decrease of $0.5 million in other assets.
 
Net cash outflows of $10.0 million from operating activities during the year ended December 31, 2007 primarily resulted from our net loss of $20.5 million, a decrease of $1.0 million in deferred revenue, and an increase of $1.0 million in other assets. These uses of cash were partially offset by a decrease of $8.8 million in accounts receivables primarily due to the collection of receivables from Monsanto, an increase of $1.2 million in accounts payable and accrued expenses, and by non-cash


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items, including $1.9 million in depreciation expense and $0.7 million in stock-based compensation expense.
 
Cash Flows from Investing Activities
 
Our investing activities consisted primarily of net investment purchases, maturities of investments and capital expenditures.
 
Net cash used in investing activities of $0.2 million during the six months ended February 28, 2011 was due to purchases of property and equipment.
 
Net cash provided by investing activities of $12.6 million during the six months ended February 28, 2010 was primarily due to $15.4 million in maturities of investments, partially offset by a $1.5 million increase in restricted cash and investments and $1.3 million in purchases of property and equipment.
 
Net cash provided by investing activities of $10.4 million during the year ended August 31, 2010 primarily resulted from $15.4 million in maturities of investments, partially offset by a $2.9 million increase in restricted cash and investments and $2.1 million in purchases of property and equipment.
 
Net cash provided by investing activities of $16.3 million during the eight months ended August 31, 2009 primarily resulted from $48.2 million in maturities of investments, partially offset by $30.3 million in purchases of investments, and $1.6 million in purchases of property and equipment.
 
Net cash provided by investing activities of $23.4 million during the year ended December 31, 2008 primarily resulted from $74.0 million in maturities of investments and a $2.6 million decrease in restricted cash and investments, partially offset by $49.4 million in purchases of investments, and $3.8 million in purchases of property and equipment.
 
Net cash used in investing activities of $53.8 million during the year ended December 31, 2007 primarily resulted from $58.1 million in purchases of investments and $2.3 million in purchases of property and equipment, partially offset by $6.4 million in maturities of investments.
 
Cash Flows from Financing Activities
 
Net cash used in financing activities of $1.1 million during the six months ended February 28, 2011 was primarily due to loan repayments.
 
Net cash provided by financing activities of $3.0 million during the six months ended February 28, 2010 was primarily due to amounts received under a loan agreement with a bank.
 
Net cash provided by financing activities of $26.6 million during the year-ended August 31, 2010 was primarily due to $20.0 million in proceeds from the issuance of Series G Preferred stock and common stock warrants and $7 million in amounts received under a loan agreement with a bank, partially offset by loan repayments totaling $0.5 million.
 
Net cash used in financing activities was $6,000 during the eight months ended August 31, 2009.
 
Net cash used in financing activities of $0.3 million during the year ended December 31, 2008 was primarily due to repayments on borrowings.
 
Net cash provided by financing activities of $73.1 million during the year-ended December 31, 2007 was primarily due to $74.2 million in proceeds from the issuance of Series F Preferred stock and common stock warrants partially offset by loan repayments totaling $1.5 million.


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Contractual Obligations
 
The following is a summary of our contractual obligations as of February 28, 2011 (unaudited):
 
                                                 
                                  2015 and
 
Contractual Obligations
 
Total
   
2011
   
2012
   
2013
   
2014
   
Beyond
 
    (In thousands)  
 
Operating Lease Obligations
    2,393       466       824       620       368       115  
Interest Payments Relating to Long-Term Debt
    446       162       215       69              
Research Collaboration Agreements
    3,550       1,271       1,984       251       44        
Long-Term Debt
    5,287       1,089       2,175       2,019       4        
                                                 
Total
    11,676       2,988       5,198       2,959       416       115  
                                                 
 
Off-Balance Sheet Arrangements
 
We did not have during the periods presented, and we do not currently have, any off-balance sheet arrangements, as defined under SEC rules, such as relationships with unconsolidated entities or financial partnerships, which are often referred to as structured finance or special purpose entities, established for the purpose of facilitating financing transactions that are not required to be reflected on our consolidated balance sheets.
 
Seasonality
 
The sale of seeds is dependent upon planting and growing seasons, which vary from year to year, and are expected to result in both highly seasonal patterns and substantial fluctuations in quarterly sales and profitability. Our product sales for the year ended August 31, 2010 and the six months ended February 28, 2011 were minimal and, accordingly, we have not yet experienced the full nature or extent to which our business may be seasonal. We expect that the sale of our seeds in Brazil will typically be higher in our first and fourth fiscal quarters, due to the timing of the planting decisions made by our customers. As we increase our sales in our current markets, and as we expand into new markets in different geographies, it is possible we may experience different seasonality patterns in our business. Weather conditions and natural disasters, such as heavy rains, hurricanes, hail, floods, tornadoes, freezing conditions, drought or fire, also affect decisions by our customers about the types and amounts of seeds to plant and the timing of harvesting and planting such seeds. Disruptions that cause delays by our customers in harvesting or planting can result in the movement of orders to a future quarter, which would negatively affect the quarter and cause fluctuations in our operating results.
 
Inflation
 
We believe that inflation has not had a material impact on our results of operations for the year ended December 31, 2007, the year ended December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, or for the six months ended February 28, 2010 and 2011. There can be no assurance that future inflation will not have an adverse impact on our operating results and financial condition.
 
Quantitative and Qualitative Disclosures about Market Risk
 
We are exposed to the effect of interest rate changes, foreign currency fluctuations and changes in commodity prices. We are also exposed to changes in the general economic conditions in the countries where we conduct business, which currently is substantially all in the United States and Brazil. As of February 28, 2011, we had only cash, cash equivalents and restricted cash, and therefore we were not exposed to changes in equity or debt prices. Our current investment strategy is to invest in financial instruments that are highly liquid, readily convertible into cash and which mature


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within three months from the date of purchase. To date, we have not used derivative financial instruments to manage any of our market risks or entered into transactions using derivative financial instruments for trading purposes. All of the potential changes noted below are based on sensitivity analyses performed on our financial position as of February 28, 2011. Actual changes may prove to be greater or less than those hypothesized.
 
We do not believe our cash equivalents have significant risk of default or illiquidity. While we believe our cash equivalents do not contain excessive risk, we cannot provide absolute assurance that in the future our investments will not be subject to adverse changes in market value. In addition, we maintain significant amounts of cash and cash equivalents at one or more financial institutions that are in excess of federally insured limits. We cannot be assured that we will not experience losses on these deposits.
 
Interest Rate Risk
 
Our exposure to market risk for changes in interest rates primarily relates to our equipment loans, which are variable-rate debt obligations. As of February 28, 2011, we had two tranches of equipment loans outstanding amounting to $5.3 million at an interest rate of 6.0% (Prime Rate plus 2.75%). If interest rates increase by 100 basis points related to the outstanding amounts as of February 28, 2011, our interest expense would change by approximately $53,000 on an annual basis prior to considering monthly principal repayment.
 
Foreign Currency Risk
 
We have foreign currency risks related to our operating expenses denominated in currencies other than the U.S. Dollar. Changes in exchange rates between the U.S. Dollar and other currencies will result in increases or decreases in our costs and earnings, and also may affect the book value of our assets outside the United States. To date, most of our contracts have been entered into in the United States and accordingly have been denominated in U.S. Dollars. Going forward we anticipate that our sales will be denominated in the local currency of the country in which the sale occurs. In addition, our operating expenses to date have been denominated in the currencies of the countries in which our operations are located, primarily the United States and Brazil. As a result, while our revenue and operating expenses are mostly hedged on a transactional basis, the translation of our operating results into U.S. Dollars may be adversely impacted by strengthening U.S. currency.
 
Through February 28, 2011, our operations in Brazil have not been significant and therefore fluctuations in the Brazil Real have had a minimal impact on our results of operations. As our international operations in Brazil grow, the risks associated with fluctuations in the Brazil Real will become greater, and we will continue to reassess our approach to managing this risk.
 
Commodity Risk
 
Our exposure to market risk for changes in commodity prices currently is minimal. As our commercial operations grow, our exposure will relate mostly to the demand side as our customers are highly exposed to fluctuations in prices of sugar and crude oil and somewhat exposed to fluctuations in agricultural commodities, especially soybean. For example, if the price of sugar, which is produced from sugarcane and which cannot be produced from sweet sorghum today, rises significantly relative to the price of ethanol, it may become more profitable for ethanol mill operators to grow sugarcane even in adverse conditions, such as through the expansion of sugarcane fields to marginal land or the extension of the sugarcane harvesting season. During sustained periods of significantly higher sugar prices, demand for our seeds may decrease, which could materially and adversely affect our operating results. We are also indirectly exposed to fluctuations in soft commodities prices like soybean when we negotiate production contracts with seed producers. We currently do not use derivative financial instruments to hedge any price volatility of agricultural commodities.


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Recent Accounting Pronouncements
 
In October 2009, the FASB issued Accounting Standards Update, or ASU, No. 2009-13, Revenue Recognition (Topic 605): Multiple Deliverable Revenue Arrangements. ASU No. 2009-13 addresses how to determine whether an arrangement involving multiple deliverables contains more than one unit of accounting and how to allocate consideration to each unit of accounting in the arrangement. This ASU replaces all references to fair value as the measurement criteria with the term selling price and establishes a hierarchy for determining the selling price of a deliverable. ASU 2009-13 also eliminates the use of the residual value method for determining the allocation of arrangement consideration. This standard was adopted by us on September 1, 2010 and the adoption of this standard did not have a material impact on our consolidated financial statements.
 
Effective September 1, 2010, we adopted ASU No. 2010-06, Fair Value Measurements and Disclosures, which requires previous fair value hierarchy disclosures to be further disaggregated by class of assets and liabilities. A class is often a subset of assets or liabilities within a line item in the balance sheet. In addition, significant reclassifications between Levels 1 and 2 of the fair value hierarchy are required to be disclosed. These additional requirements became effective September 1, 2011 for quarterly and annual reporting. Their adoption did not have any impact on our financial statements. In addition, ASU 2010-06 requires more detailed disclosures regarding changes in Level 3 instruments. This disclosure change will be effective September 1, 2012 and is not expected to have an impact on our consolidated financial statements.
 
In April 2010, the FASB issued an ASU No. 2010-17, Revenue Recognition — Milestone Method (Topic 605): Milestone Method of Revenue Recognition. The standard provides guidance on defining a milestone and determining when it may be appropriate to apply the milestone method of revenue recognition for research or development transactions. Research or development arrangements frequently include payment provisions whereby a portion or all of the consideration is contingent upon milestone events such as successful completion of phases in a study or achieving a specific result from the research or development efforts. The amendments in these standards provide guidance on the criteria that should be met for determining whether the milestone method of revenue recognition is appropriate. The standard is effective for fiscal years and interim periods within those years beginning on or after June 15, 2010, with early adoption permitted, and applies to milestones achieved on or after that time. This standard was adopted by us on September 1, 2010 and the adoption of this standard did not have a material impact on our consolidated financial statements.


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BUSINESS
 
Our Company
 
We are an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks that can enable the large-scale replacement of petroleum and other fossil fuels. We use a combination of advanced plant breeding and biotechnology to develop new crops, known as dedicated energy crops, that we believe address the limitations of first-generation bioenergy feedstocks, such as corn and sugarcane, increase biomass productivity, reduce crop inputs and improve cultivation on marginal land.
 
Our first large-scale commercial products are proprietary sweet sorghum varieties that can be used as a “drop-in” feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills, the operating days of which are currently limited due to the inherent limitations of sugarcane physiology and growth patterns. Our dedicated energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Finally, baseload utility-scale electric power can also be generated from the biomass feedstocks grown from our seeds.
 
The seed industry has historically required very little capital to manufacture seeds, and seeds have typically been sold at prices that generate high gross margins. As a producer of proprietary seeds, we believe we are in the most attractive segment of the bioenergy value chain — upstream from the capital intensive refining and conversion of biomass. For example, in 2009 corn seed providers maintained high margins when volatile commodity prices significantly impacted corn ethanol refining margins. Therefore, we believe our success is tied to adoption of our products rather than the relative profitability of downstream participants. Our upstream position in the value chain also allows us to be largely independent of the success of any particular conversion technology or end use.
 
We develop low input dedicated energy crops capable of producing high yields of biomass per acre using innovative plant breeding and trait biotechnology. By developing these types of crops, we enable the scalable, sustainable and economic production of bioenergy, or the energy derived from biomass. Our proprietary collection of energy crop parent lines, known as germplasm, in combination with our pipeline of biotechnology traits allows us to develop bioenergy feedstocks to meet the needs of both biomass refineries and growers of biomass, all while using less water and less fertilizer than row crops like corn or soybean, even if grown on marginal land. We believe that the strength of our technology has been validated by the receipt of multiple competitive grants and collaborations, including a United States Agency for International Development, or USAID, grant and one of the U.S. Department of Energy’s first Advanced Research Project Agency for Energy, or ARPA-E, grants in 2009, as well as a $137 million multi-year collaboration with Monsanto Company signed in 2002. We also have significant intellectual property rights to our technology.
 
We recently began marketing sweet sorghum seeds in Brazil and have sold switchgrass and high biomass sorghum seeds in the United States under our brand, Blade Energy Crops, or Blade. Our largest immediate commercial opportunity is the Brazilian ethanol market, which currently uses sugarcane as its predominant feedstock. Due to the inherent limitations of sugarcane physiology and growth patterns, Brazilian mill operators, which have an estimated 3.4 million metric tons per day of crushing capacity, can only obtain usable sugarcane approximately 200 days per year. Boa Vista / Nova Fronteira, a joint venture of Grupo São Martinho S.A. and Petrobras Biofuels, recently planted, harvested and processed a commercial-scale planting of our sweet sorghum products and produced both ethanol and power using the existing agricultural equipment and processing infrastructure. Similar activities are in process with two other Brazilian ethanol producers, ADM do Brasil Ltda, and Usina Rio Pardo S.A. We believe the success of our first commercial-scale planting demonstrates the “drop-in” nature of our sweet sorghum products, and along with seed-based propagation, shorter growing cycles and lower water and fertilizer requirements of sweet sorghum relative to sugarcane, will serve as the basis for expanded adoption of this product line as a feedstock for ethanol and power


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production in Brazil and other markets. We believe the adoption of our sweet sorghum hybrids could extend a mill’s operations by approximately 60 days.
 
We also work with refining technology companies in the emerging cellulosic biofuels and bio-based chemicals markets. We believe that dedicated energy crops will enable both individual renewable energy projects and the industry as a whole to reach greater scale and sustainability, at lower costs, than other potential sources of biomass. We believe our dedicated energy crop portfolio is compatible with a number of developing cellulosic biofuels conversion technologies and we are working with companies focusing on petroleum-refining technologies, such as UOP, LLC, as well as chemical companies, such as Gruppo Mossi & Ghisolfi, or Gruppo M&G, to test our energy crops in their respective production processes. We have also conducted joint trials with, or sold seed to, AGCO Corporation, EdeniQ, Inc. and Hawai’i BioEnergy, LLC, among others. We recently began a collaboration with Valero Services, Inc. to further evaluate feedstock supply strategies with dedicated energy crops.
 
Our dedicated energy crops also can be used to generate electricity in existing solid-fuel power facilities, such as coal-fired generating plants. We believe we will see a material increase in demand for biopower in the event that additional renewable energy legislation is passed in the United States, Europe or other countries that requires a higher percentage of generation from low-carbon sources or provides equal production incentives for the co-firing of biomass with coal, as are currently available for wind and solar power. We believe that our products can be used by existing growers, pellet mills and utilities, and can be cost competitive with existing biopower feedstocks, such as wood pellets.
 
Finally, due to the nature of biotechnology, we believe other crops can benefit from many of the traits we are developing for dedicated energy crops, such as traits that improve water use efficiency and salt tolerance. By combining genes into a series of stacks, we believe that we can achieve step-change improvements to the productivity of many row crops, including corn, soybean, rice and wheat. We have also generated many biotech traits specifically for cereal crops, such as rice, that increase grain yields and provide greater yield stability across different environments. We are inserting these and other traits into commercial rice varieties and plan to trial them in multiple locations in Asia this year.
 
Market Opportunity
 
The world continues to seek economic and environmentally sound alternatives to fossil fuel-based transportation fuels and power. We believe bioenergy is one of the few viable replacements for fossil fuels. Unlike other renewable technologies, biofuels are intended to utilize existing vehicles and transportation fuel infrastructure. Similarly, biopower, unlike wind and solar power, can provide baseload and dispatchable generation of renewable electricity. Despite the potential of biofuels, first-generation biofuel feedstocks have demonstrated their limitations in terms of scale, perceived competition with food production, net energy balance, and dependence on government subsidies. Similarly, current sources of biomass, such as forestry residues and agricultural wastes, are limited in scale and are not optimized for use in bioenergy. They are also by-products derived from other processes and therefore subject to supply disruptions. Our dedicated energy crops provide an attractive combination of high yield density, high net energy balances, low input requirements, the ability to grow on marginal land and, as a dedicated source of feedstock, the potential to be tailored for specific production and refining processes. We believe that dedicated energy crops will become a critical component for growth of the biofuel, bio-based chemicals and biopower markets.
 
Biofuels and Bio-Based Chemicals
 
Modern lifestyles and economies are highly reliant on petroleum and its by-products across a wide variety of industries, including light-duty transportation, aviation, diesel, shipping, lubricants, polymers, resins and cosmetics. According to the U.S. Energy Information Administration, or EIA, global oil production averaged 87.9 million barrels per day in the first quarter of 2011. The


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transportation fuel component of petroleum is valued at over $2 trillion per year, according to EIA. The vast majority of bio-based replacements for petroleum and petroleum-based chemicals are currently produced by fermentation of starch sources and free sugars primarily derived from corn and sugarcane, respectively. Commonly referred to as first-generation biofuels and bio-based chemicals, the production and conversion processes for these feedstocks are well-established. However, as the world looks to increase its consumption of biofuels and their derivatives, these first-generation feedstocks face challenges to meet increased demand.
 
In Brazil, where the country has recently been importing corn ethanol to meet its demand, we believe that mill operators will seek alternatives that will allow them to increase production utilization of their existing mills beyond the average 200 days per year schedule. On a global basis, we expect petroleum consumption will be further replaced by products made from the conversion of non-food biomass into biofuels and bio-based chemicals. Today, there are multiple companies, including large multinational companies, such as BP p.l.c., Royal Dutch Shell plc, Total S.A. and Valero Energy Corporation, and independent companies, such as KiOR, Inc. and Coskata, Inc., focused on improving non-food biomass conversion technologies. According to the International Energy Agency, or IEA, biofuel production could reach approximately 112 billion gallons per year by 2030, up from 26 billion gallons in 2010. To meet these targets, the IEA believes feedstock production would need to increase to 150 million acres in 2030, up from 75 million acres in 2010. We believe quadrupling the volume of biofuels while only doubling the feedstock production acres will require higher yielding second-generation feedstocks.
 
Biopower
 
Globally, 7.92 trillion kilowatt-hours of electricity were generated from coal in 2007, or 42% of total global power generation, according to the EIA, which we estimate required 3.6 billion tons of coal. By comparison, the EIA reports that globally, approximately 235 billion kilowatt-hours of electricity were generated from biomass and wastes, or 57% of all renewable energy generation, excluding hydropower, which we estimate required 200 million dry tons of biomass. The conversion of biomass to power has traditionally been fueled by bio-based waste products and residues from the paper and timber industries. As is the case for biofuels, we believe this practice has limited the size, location, efficiency and scale of biomass power generation because power producers can not reliably secure long-term supplies of consistent quality feedstock. We believe we will see a material increase in demand for biopower in the event that additional renewable energy legislation is passed in the United States, Europe or other countries that requires a higher percentage of generation from low-carbon sources, or that incentivizes the co-firing of biomass.
 
Food and Feed Crops
 
According to the International Service for the Acquisition of Agri-Biotech Applications, or ISAAA, approximately 366 million acres of biotechnology crops were planted globally in 2010. The global market value of biotechnology crop seeds was $11.2 billion, as reported by ISAAA. As people in many countries become more affluent, they tend to consume more of their dietary protein in the form of meat and dairy products, driving the demand for animal feed grains higher. Therefore, greater production of food, feed, fiber and fuel will require higher crop productivity levels among all crops over time. In order to continue the productivity gains made in many crops over the past 75 years, and to do so in a more sustainable manner, we believe that advanced breeding methods, and biotech traits, in particular, will be required to produce higher performance crops that make more productive use of cultivated land, as well as to develop more robust, stress-tolerant crops that can grow under more difficult conditions and on marginal land.
 
Our Solutions
 
We believe that nearly all bioenergy and bio-based chemical applications will ultimately depend on high yielding, low-cost, low-carbon, scalable, reliable and sustainable sources of feedstock. We


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believe biomass from our dedicated energy crops and traits have the potential to become the common denominator in a broad array of bio-based products, including ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, as well as electric power and heat, and can enable the development of larger-scale processing facilities given the high yield density and conversion efficiency of dedicated energy crops. Specifically, our dedicated energy crops have the following characteristics, which we believe will make them a critical component in the large-scale production of these bio-based products:
 
“Drop-in” Products
 
Our products are “drop-in” solutions because they can be planted, harvested and processed using existing agricultural equipment with little or no modification and are being developed to be “drop-in” for all conversion technologies using sugarcane or biomass feedstocks, facilitating their rapid adoption. In collaboration with Boa Vista/Nova Fronteira, a joint venture of leading ethanol producers Grupo São Martinho, S.A. and Petrobras Biofuels, we recently completed a commercial-scale trial on approximately 250 hectares of our sweet sorghum, which was planted and harvested using existing planting and harvesting equipment, fermented into ethanol without retrofitting or altering the existing mill and the remaining biomass combusted for electricity production, using existing boilers. We have also conducted smaller trials using our other energy crops with numerous industry participants involved in cellulosic biofuels and biopower production. Our products have been tested in the respective conversion processes of Amyris Biotechnologies, Inc., Choren USA LLC, EdeniQ, Inc., Gruppo M&G, ICM, Inc., Novozymes North America, Inc., ThermoChem Recovery International, Inc. and UOP, LLC (a Honeywell company), among others. DuPont Danisco Cellulosic Ethanol LLC, or DDCE, also plans to validate our products in their conversion process.
 
High Yield Density
 
Our dedicated energy crops are developed to produce high biomass or sugar yields per acre. For cellulosic biofuels, bio-based chemicals and biopower, energy grasses can yield significantly more dry tons per acre per year compared to agricultural residues and woody biomass. This maximizes the productivity of available land and shortens the collection radius for a conversion facility of a particular size. As transportation costs can be a significant element in the total cost of biomass, we believe our high yield density crops will facilitate the construction of larger processing facilities because more biomass could be collected from a defined area of land around the facility. In turn, these larger facilities will benefit from economies of scale, resulting in lower production and capital cost per gallon produced.
 
Dedicated to Bioenergy
 
Unlike many other bioenergy feedstocks, our dedicated energy crops are currently not intended for other uses and are typically grown exclusively to be harvested as part of the bioenergy value chain, creating a stable supply that will appeal to owners of conversion technologies who will have invested significant capital in their infrastructure and will therefore require reliable and cost-effective feedstocks. Additionally, we are working to tailor our products to improve the efficiency and reduce the cost of certain conversion technologies. For example, we are developing a trait that reduces enzyme requirements to convert biomass into certain bio-based products. As high enzyme costs continue to be an issue for some biochemical cellulosic conversion technologies, this trait could be very valuable to refineries employing those technologies. We believe that our ability to deliver products such as these to our customers will facilitate adoption of dedicated energy crops over other forms of biomass.
 
Suited to Marginal Land
 
Our dedicated energy crops can grow in a broad range of environments, including those not well-suited for most food crops. For example, our sweet sorghum hybrids need substantially less water and fertilizer than sugarcane to grow to harvestable maturity. We are developing biotech traits that


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provide salt tolerance, drought tolerance and greater nitrogen use efficiency. We believe that by facilitating the use of marginal land, our crops will create opportunities for landowners who previously could not use their land as productively.
 
Scalable to Meet Demand
 
Our energy crops are highly scalable, allowing us to match our production with growing demand for our seeds on relatively short notice compared to sugarcane, which can take several years to scale up commercially. Our products are generally seed-propagated, similar to row crops such as corn and soybean, which makes them cost-effective to plant on a large scale using existing seed planting equipment. Several of our products also have shorter growing cycles and can be rapidly cultivated as compared to other feedstocks, such as trees or sugarcane. For example, sweet sorghum has growth cycles ranging from 90 to 140 days, while sugarcane has a 12 to 18 month growth cycle and a more laborious planting process because it is vegetatively propagated.
 
Competitive Strengths
 
We believe that we possess a number of competitive strengths that position us to become a leading provider of dedicated energy crop seeds and traits, including:
 
Commercial Products Available Today
 
We currently have a number of commercially available seed products, including sweet sorghum, switchgrass and high biomass sorghum. Our sweet sorghum hybrids have recently been successfully planted, harvested and processed into ethanol and power in Brazil in our first commercial-scale project. We are in active discussions with a number of Brazilian ethanol producers for use of our sweet sorghum seeds for the 2011-2012 growing season. We believe our demonstrated success in the 2010-2011 growing season will facilitate the rapid development of this market and enable the expansion of our market share in Brazil and in other geographies.
 
Attractive Business Model
 
Seed businesses traditionally incur significant research and development expenditures and have long product development time lines, but benefit from a combination of high gross margins, low capital expenditure requirements and intellectual property protection. Once developed, seeds require little physical infrastructure or production cost to be replicated for sale. Seeds are typically priced, however, based on a share of the value created to the customer as opposed to their cost of production. In general, seed costs to a grower are a relatively small percentage of their total production cost, but the performance of those seeds are critical to the growers’ economics. We believe we can position our business to take advantage of low production costs relative to the high value of our products to our customers.
 
Innovative R&D Technology Platforms
 
In order to maintain the strong position we have established with our combined strengths in germplasm and field-validated traits, we use our research and development expertise to continually improve our product offerings. To develop higher performing varieties and traits, we use several advanced research and development methods, including biotechnology, marker-assisted breeding and genomics. We believe that our innovative integrated breeding and biotechnology approach allows us to efficiently identify traits, effectively express these traits in crops, and more quickly commercialize new and improved seeds and traits for the market. We have both biotech traits and non-biotech traits, and some of the biotech traits have been successfully evaluated in the field; however, they are still several years away from commercialization. We believe we were one of the first companies to implement the practice of developing biotech traits using two test species, rather than just one, which allows us to more successfully select gene-trait combinations that enhance commercial crops. In order


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to capitalize upon our internal “catalog” of genetic information as well as information in the public realm, we developed our own proprietary software, including our Persephone genome viewer software, which serves as an important tool for locating, mapping and annotating genetic information in plants. This software program was recently licensed by a major agro-chemical company. We believe that our ability to continue to apply our advanced research and development methods will enable us to further enhance our proprietary germplasm and traits portfolios going forward.
 
Extensive Proprietary Portfolios of Germplasm and Traits
 
While many companies have developed portfolios of germplasm or traits, we believe we are one of the only companies focused on dedicated energy crops with large portfolios of both germplasm and field-validated traits. Having both germplasm and field-validated trait portfolios allows us to leverage the synergies created by combining the two and facilitates innovation in a way that would not be possible with germplasm or traits alone. We have leveraged our access to leading germplasm for sweet sorghum, high biomass sorghum, switchgrass and miscanthus through strategic collaborations with leading institutions and established in-house programs. We believe new market entrants would need to cultivate several generations of germplasm to achieve performance equivalent to our current product portfolio, by which time we believe we will have further evolved our germplasm. Therefore, we believe our proprietary position would be difficult and time-consuming to replicate. We believe that we have established a strong intellectual property position in plant genes, traits and energy crop germplasm. As of April 30, 2011, we owned or had exclusive licensed rights to approximately 110 issued patents and approximately 200 pending patent applications in the United States and in various foreign jurisdictions.
 
Management Team with Significant Industry Experience
 
Our Chairman, Walter De Logi, is one of the founders of Ceres. Mr. De Logi and Richard Hamilton, our Chief Executive Officer, have been with Ceres for 15 and 13 years, respectively, and have extensive experience in the field of agricultural biotechnology. Our experienced management team possesses a deep understanding of a variety of agricultural, chemical and industrial biotechnology businesses, including the seed industry, as well as our regional markets of Brazil, the United States and Europe. Our management team also includes top scientists and industry experts, some of whom have served in leadership roles at large, multinational corporations, served on advisory committees for the U.S. Department of Energy, led ground-breaking research studies and published numerous scientific articles.
 
Our Strategy
 
Our objective is to be the leading provider of dedicated energy crop seeds and traits to the renewable energy industry, including first-generation biofuels such as ethanol as well as cellulosic biofuels, biopower and bio-based chemicals by employing the following strategies:
 
Expand Our Presence in Brazil
 
Boa Vista/Nova Fronteira, a joint venture of leading ethanol producers Grupo São Martinho, S.A. and Petrobras Biofuels, recently planted, harvested and processed a commercial-scale planting of our sweet sorghum products and produced both ethanol and power using existing agricultural equipment and processing infrastructure. We intend to use our recent success to promote brand awareness and expand our presence in Brazil by partnering with additional ethanol mills and other industry participants to conduct field trials and larger-scale commercial plantings as well as introduce new products into the Brazilian market. We will continue to position our seeds in the Brazilian market as a premium brand that incorporates the latest technology in energy crops. We are in active discussions with a number of other Brazilian ethanol producers for use of our sweet sorghum seeds for the 2011-2012 growing season. We believe the adoption of sweet sorghum in Brazil can follow similar


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rapid adoption curves seen for other seed and agricultural innovations such as hybrid corn in the United States and herbicide-tolerant soybean in the Americas.
 
Expand Strategic Collaborations to Develop and Market Cellulosic Biofuels
 
We plan to play a significant role in developing the second-generation biofuels and bio-based chemicals market, which we believe represents a significant opportunity. Our switchgrass and high biomass sorghum products are specifically targeted at this market. We intend to establish new collaborations and expand upon our current collaborations with leading cellulosic biorefining companies, technology providers and project developers to further validate our products across various downstream technologies and to produce optimized feedstocks that are tailored to meet the specifications of existing and new refining technologies. Our products have been tested in the respective conversion processes of several companies, including Choren USA LLC, EdeniQ, Inc., Gruppo M&G, ICM, Inc., Novozymes North America, Inc., ThermoChem Recovery International, Inc. and UOP, LLC. DDCE also plans to validate our products in their conversion process. We have also conducted joint trials, or sold seed to, AGCO Corporation, EdeniQ, Inc. and Hawai’i BioEnergy, LLC, among others. We recently began collaborating with Valero Services, Inc. to further evaluate feedstock supply strategies with dedicated energy crops.
 
Expand Our Business into New Markets
 
We intend to market our Blade Energy Crops brand as a symbol of quality, innovation and value across multiple biofuel, bio-based chemicals and biopower markets in a broad range of climates and geographies. We intend to use our large portfolios of field-validated traits and germplasm, combined with our advanced technology platforms, to develop products for a wide variety of niches and seize upon future market opportunities, regardless of the fuel or chemical molecule (e.g., ethanol, butanol, farnesene, biogasoline, biodiesel, biocrude), biochemical (e.g., bioplastics, lubricants) or engine choice (e.g., all electric, E85, E15, diesel, hybrid, plug-in hybrid).
 
Build New Relationships and Enhance Established Collaborations in the Global Biopower Market
 
Our switchgrass, high biomass sorghum and miscanthus crops can be used in power generation generally, and in particular, for co-firing with coal using the existing power generation infrastructure. To date, we have engaged in field trials of our energy crops with utility companies and independent power producers. We intend to cultivate collaborations with new parties, particularly those in Europe where we believe the market opportunity for biopower is more established today and the market need is more immediate in light of existing government regulations. We will work with utility companies and independent power producers to drive demand for our dedicated energy crops in the biopower market.
 
Continue Innovation and New Product Development
 
We are continuing to develop innovative solutions using a broad range of technological tools, including genomics, biotechnology and proprietary bioinformatics in order to produce crop varieties with improved yields and other performance characteristics. We believe we can accomplish these goals by finding innovative ways to utilize and combine traits and germplasm to further enhance our products. In addition, we will continue to develop varieties of seeds to meet the specific needs of growers in different geographic regions. For example, we have identified traits that will help optimize results for growers located in geographies with varying day lengths, rainfall, temperatures and soil composition (e.g., salt, aluminum and nitrogen).
 
Continue to Build Our Intellectual Property Portfolio
 
We believe we have established a strong intellectual property position in plant genes, traits and energy crop germplasm. We believe we are one of the few companies focused on dedicated energy crops that have this combination of intellectual property assets. We use our integrated technology


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platforms to continually improve our products and develop innovations that will further strengthen our intellectual property position.
 
Our Technology Platforms
 
Our integrated technology platforms are a combination of existing genetic assets, specifically germplasm and traits, and competences in genomics, biotechnology and bioinformatics. Integration of these platforms allows us to improve our existing genetic assets as well as develop and commercialize new products from them. This combination of assets and research and development capability has resulted in one of the largest licensing transactions in the agricultural biotechnology industry, multiple competitive grants and collaborations, including a USAID grant to develop several traits in rice and one of the U.S. Department of Energy’s first ARPA-E grants in 2009. For the year ended December 31, 2008, the eight months ended August 31, 2009, the year ended August 31, 2010 and the six months ended February 28, 2011, we spent $20.3 million, $12.4 million, $16.7 million and $8.6 million, respectively, on research and development, with the main emphases on traits and breeding.
 
Germplasm
 
We believe we have access to the most comprehensive germplasm collections for our dedicated energy crops, and have assembled a leading germplasm portfolio for dedicated energy crops. Our belief is based on the diversity and nature of the entries we have and how well they are characterized, which is the method by which different characteristics are evaluated and measured, and cataloged. Germplasm comprises collections of parental lines and other genetic resources representing the diversity of a crop, the attributes of which are inherited from generation to generation. Germplasm is a key strategic asset since it forms the basis of plant breeding programs.
 
Our early entry into the energy crop industry has allowed us to acquire access to valuable germplasm through strategic collaborations with leading institutions. We believe our competitors would need to cultivate several generations of germplasm to achieve performance equivalent to our current product portfolio, by which time we will have further evolved our germplasm. Therefore, we believe that we have a strong proprietary position that would be difficult and time-consuming to replicate. We are currently involved in three major germplasm development collaborations, each with a history of successful research and germplasm development in an energy crop.
 
Switchgrass — The Samuel Roberts Noble Foundation, Inc.  In May 2006, we entered into an agreement with The Samuel Roberts Noble Foundation, a non-profit agricultural institute, for the development and commercialization of switchgrass. This relationship provides us access to extensive breeding infrastructure and exclusive licenses to elite switchgrass varieties, breeding lines and advanced cultivars.
 
Miscanthus — Institute of Biological, Environmental and Rural Sciences of Aberystwyth University.  In April 2007, we entered into an agreement with the Institute of Biological, Environmental, and Rural Sciences of Aberystwyth University in Wales, U.K., or IBERS, for morphological characterization, genetic evaluation, and the development and commercialization of miscanthus species as an energy crop. This relationship provides us access to an extensive scientific research infrastructure and includes exclusive licenses to miscanthus germplasm, breeding lines and varieties produced by IBERS, except that IBERS has a non-exclusive license in the United Kingdom to varieties resulting from the joint program.
 
Sorghum — Texas A&M University.  In August 2007, we entered into an agreement with The Texas A&M University System, or Texas A&M, for the development and commercialization of high biomass sorghum, sweet sorghum and selected related crops as energy crops, together with the discovery of molecular markers for certain traits. This relationship provides us with access to a highly regarded sorghum breeding program and the extensive sorghum genetics, breeding and genomics infrastructure of Texas A&M. This agreement provides exclusive options and licenses to elite sorghum breeding lines, parental lines, advanced hybrids and genomic markers.


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Our Traits
 
We are able to further improve the quality of our future product offerings by adding our proprietary traits to our germplasm collections. This can provide additional yield increases, greater water use efficiency, increased nitrogen use efficiency, salt tolerance, enhanced biomass-to-sugar conversion profiles and other improved characteristics. We believe that our integrated breeding and biotechnology approach allows us to efficiently identify traits, effectively express these traits in crops and more quickly commercialize new and improved seeds and traits for the market. We target traits with the greatest commercial potential in energy crops. We believe these traits will enable the bioenergy industry to scale more rapidly, by improving production and delivery economics, making greater use of marginal land, providing greater yield stability and increasing energy yield per acre.
 
We have both genetically engineered traits, or biotech traits, and non-biotech traits. In some instances, a gene introduced through biotechnology may confer more than one beneficial trait, such as salt tolerance and drought tolerance, or increased biomass yields through greater nitrogen use efficiency. Our strategy is to focus on genes and gene stacks that have shown large, step increases in performance, and whose benefits are largely maintained across multiple species.
 
Biotechnology allows us to precisely add traits not readily feasible through conventional breeding methods. In many cases, the same trait can be added to multiple crops with similar effect. For example, our genomics capabilities and proprietary gene expression system have enabled us to expand from single genes and traits to groups of genes and traits, or stacks. We also have control over how, when and where genes are expressed in plants. This system includes using recombinant DNA, cell culture, and related technology as well as gene transfer systems needed to create plants with biotech traits and optimized gene-trait combinations identified by our trait pipeline.
 
To develop biotech traits, we have utilized a novel research and development methodology. Similar to other companies, we use test or model plant systems to speed discoveries and reduce risk and technical uncertainty in the development of biotech traits. This includes evaluating gene function, regulation, interaction and potential usefulness. However, we typically utilize two test species, rather than just one, as is more customary in the industry. Our test or model plants represent the two principal evolutionary branches of flowering plants commonly known as dicots and monocots. This two-species approach allows us to more successfully select gene-trait combinations which enhance commercial crops. The small, fast-growing test plant called Arabidopsis is our model dicot, and rice is our model monocot. Rice is a grass species and a close relative of energy grasses. Our evaluations in Arabidopsis are completed at our headquarters in Thousand Oaks, California. Our high-throughput field evaluations of rice are conducted in China by the Institute of Crop Sciences of the Chinese Academy of Agricultural Sciences. We believe, and our results have confirmed, that by selecting genes that perform similarly in both our model plant species, we can readily identify superior genes among thousands of candidates. We believe that, given the large evolutionary distance between our model species, genes that function similarly in both will likely have application in a broad range of flowering crop plants. We have also identified superior genes by utilizing rice and Arabidopsis alone.
 
We also intend to stack gene-trait combinations, such as those conferring greater nitrogen or water use efficiency, together to amplify the benefits. We describe the combination of such complementary genes as “synergistic trait stacks”. This differs from many current approaches which produce incremental yield increases through the introduction of a single novel gene.
 
The following traits have been commercialized or are at various stages of development in our trait development pipeline:
 
Skyscraper
 
Skyscraper is a non-biotech, commercial trait that provides a significant increase in biomass yields and is included in our proprietary high biomass hybrids ES 5200 and ES 5201. Developed through our collaboration with Texas A&M University, the Skyscraper trait delays flowering and extends


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the growth phase of the sorghum plant’s lifecycle. Plants with the Skyscraper trait put more of their energy into growing rather than reproducing (making seeds). Since Skyscraper was identified and developed using molecular marker technology, we have been able to rapidly incorporate it into our elite breeding lines.
 
High Biomass
 
We have a number of genes that have been shown to substantially increase biomass growth per plant. We are currently field-trialing four of these genes in switchgrass in four states in the United States Second-year results have shown significant yield increases over experimental control plants. We plan to field test these genes in miscanthus and sorghum and then breed them into elite varieties. We are also creating synergistic trait stacks with these genes with the goal of achieving even greater biomass yields per plant. Yield per acre can also be increased through higher plant populations per acre. We are evaluating biotech traits that make plants grow more upright, allowing greater light capture at higher densities. We anticipate that this trait could allow growers to greatly increase the number of plants they sow per acre.
 
Nitrogen Use Efficiency
 
We have genes that increase biomass under normal and reduced nitrogen fertilizer conditions. In field trials, we have recorded steady yields on significantly less nitrogen fertilizer than normally used. In addition to greater efficiency in terms of tons of biomass per unit of nitrogen, reducing nitrogen fertilizer inputs would reduce greenhouse gas emissions, increase lifecycle energy ratios, reduce run-offs and water pollution, and lower production costs. We are currently field-testing four nitrogen use efficiency genes in switchgrass in four states in the United States. We also plan to field test these genes in miscanthus and sorghum. We are also developing synergistic trait stacks with these genes with the goal of increasing efficiency and yields.
 
Water Use Efficiency and Drought Tolerance
 
We have several genes that allow plants to use water more efficiently and/or recover from water deficits more readily. We are currently field-testing water use efficiency and drought tolerance genes in switchgrass that have resulted in the production of steady yields on less water in greenhouse tests. In addition to producing more tons of biomass per unit of water, we believe that in seasons of intermittent drought, this trait could provide greater yield stability for rain-fed crops as well as expand the geographic range where economic yields can be obtained.
 
Salt Tolerance
 
We have genes that have been shown in our greenhouse to provide tolerance and enhanced recovery to both acute and prolonged salt stress. If results are confirmed in the field, we believe that this trait could return salt-damaged acres to productivity and open more marginal land to bioenergy production. We also believe that salt tolerance is complementary to drought tolerance since salt stress tends to induce drought symptoms in plants. We are currently evaluating these and other salt tolerance genes in energy crops and rice in the greenhouse.
 
Aluminum Tolerance
 
We are developing genes that allow plants to withstand toxic levels of aluminum in the soil, a consequence of highly acidic soils, such as those found in Brazil. We believe that this trait could bring high aluminum soils into cultivation and open more marginal land to bioenergy production. We are currently evaluating these genes in multiple crops in the greenhouse.


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Enhanced Conversion of Biomass to Fermentable Sugars
 
We have developed genes that enable multi-fold decreases in the cellulase enzyme cocktails required to release fermentable sugars from plant biomass. Reducing the recalcitrance of biomass to conversion could significantly reduce enzyme costs in certain biochemical conversion processes, and could further reduce both capital and operating costs for the biorefinery. For instance, a more easily converted feedstock would impact installation costs for biorefineries since smaller holding tanks would be required for a given capacity. We believe therefore that this trait could be a key enabler of the large-scale use of biochemical processes and fermentation to produce biofuels and bio-based chemicals from cellulosic biomass.
 
Altered Flower Development
 
We are pursuing multiple approaches to regulate flower development for the purpose of increasing biomass and sugar accumulation, as well as rendering plants resistant to fungal diseases that infect flowers. Similar to the impact of our Skyscraper trait, preventing flowering or reproduction allows plants to put more of their energy into biomass growth. We are currently field-testing genes that impact different aspects of flowering, pollen production and seed development. We believe that by creating synergistic stacks of these traits we can amplify such effects. In addition, when stacked with our other traits, we believe these genes provide a stewardship advantage. In the unlikely event of an unintended outcross of a biotech trait to a wild plant, for instance, the presence of a stack that included genes that disrupt floral development and reproduction should put the resulting plant at a severe reproductive disadvantage, thereby limiting the spread of unintended progeny plants.
 
Research and Development Programs
 
In order to maintain the lead we have established through our combination of superior germplasm and field-validated traits, we have developed research and development expertise that we believe will allow us to continue to improve our offerings over time. To develop higher performing seeds and traits, we deploy a variety of research and development methods and tools, including genomics, conventional and marker-assisted breeding, agronomy and other genomics-based technologies.
 
Genomics
 
Plant genomics involves the large-scale, simultaneous study of large numbers of genes, their effects and their interactions. One of our strengths in genomics involves our ability to organize the genetic data we amass into actionable information via proprietary relational databases, software and algorithms. We believe that both our technological capabilities and proprietary knowledge base in this area are highly advanced, and their application to both our breeding program, through the development of trait-linked molecular markers, and our trait development program provides us a substantial competitive advantage.
 
In general, we have focused our research efforts on determining gene function, gene regulation and finding which genes enhance desirable traits. In addition to identifying novel gene-trait combinations, our genomics tools allow us to work with large groups of genes and complex biological processes controlled by multiple genes. To date, we have sequenced more than 100,000 full-length copies of DNA, called cDNA, from a variety of plant species. We have also identified and characterized hundreds of promoters that can be important for achieving the optimum expression of traits. We believe we are one of the few companies focused on dedicated energy crops with large portfolios of both germplasm and field-validated traits. Having both germplasm and trait portfolios allows us to leverage the synergies created by combining the two and facilitates innovation in a way that would not be possible with germplasm or traits alone.


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Conventional and Marker-Assisted Breeding
 
Plant breeding is the act of bringing together specific parent plants to produce a new “offspring” plant. This “cross”, as plant breeders call it, creates a new plant that will contain a mixture of the characteristics of its parents. The offspring are tested under various conditions to determine which has the superior combination of desired attributes. Further improvements are made by mating and continuing selection of superior parents and offspring through additional generations. Plant breeding allows researchers to identify plants with the most favorable combination of desired characteristics to serve as both parental lines and products.
 
In addition to conventional plant breeding, we believe that our genomics expertise makes the identification of proprietary molecular markers more direct and more comprehensive, which allows us to select key crop characteristics more rapidly and accurately than conventional plant breeding alone. Marker-assisted breeding integrates molecular biology and information systems with plant breeding to identify important genetic sequences and flags them so that they can be readily found in seeds or plant tissue at any stage of plant development. This platform allows us to track and select the most effective combination of genes, increase the number of progenies and breeding lines created at early stages in the breeding program, cull them using marker-based selection and, hence, make greater gains per breeding cycle. Markers are especially useful when seeking to combine multiple non-biotech traits into elite commercial lines.
 
We have developed thousands of SNP-based (single nucleotide polymorphism) molecular markers, which allow us to differentiate individual plants based on variations detected at the level of a single nucleotide base in the genome. SNPs allow us to automate many processes and are especially useful for hybrid breeding systems. Most importantly, we precisely map these SNPs onto the chromosomes of switchgrass, sorghum and miscanthus, and then link them to important traits by genetic analyses and then deploy them in our breeding programs using proprietary computational biology software systems. Furthermore, when an important gene is developed in one crop, we can often find the equivalent gene in another related crop using our genomics and molecular marker platforms to gain breeding advantages across crops.
 
Agronomy
 
The performance of plant varieties and traits is influenced by the growing environment, which includes climate, day length, soil quality, pests, length of the growing season and crop management practices. We have established what we believe is one of the industry’s largest network of field trials for energy grasses, based on the number of trials and geographic diversity. Extending across numerous hardiness zones and regions, including Europe, the Americas and Asia, this network provides regional performance data and market fit information to support our research and commercialization efforts.


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Our Product Pipeline
 
We believe that a portfolio of energy crops will be required to produce biofuel, biopower and bio-based chemicals at greater scale than today. The mix of crops will be heavily dependent upon geographic and climatic considerations, soil quality, storage characteristics and harvest timing, among other considerations.
 
The following table summarizes our current product pipeline:
 
                               
                  Initial
          Traits Under
 Crop     Status     Seed Varieties     Market     Key Advantages     Development
Sweet Sorghum
    Commercial
Ready
(2011-2012*)
    >10 products in
registration**
    Brazil     Season
extension; fast
growing; quick
scale up; low
water usage
    High sugars, delayed
flowering, NUE+ and
WUE+
High Biomass
Sorghum
    Commercial
(2009)
   
ES 5200 with
Skyscraper

ES 5201 with
Skyscraper
ES 5140
ES 5150
ES 5155
    USA and
Brazil
    High yields;
fast-growing;
low water usage
    Field validation of
high biomass/NUE+
traits scheduled for
2012
Switchgrass
    Commercial
(2009)
    EG 1101
EG 1102
EG 2101
    USA and
Europe
    High yields;
low water
usage; perennial
crop
    Field validation of
high
biomass/NUE+/WUE+
traits ongoing in AZ,
GA, TN and TX
Miscanthus
    Under
development
    Seed-propagated
varieties under
development
    USA and
Europe
    High yields;
highly efficient,
perennial crop
    High biomass/NUE
field validation
scheduled for 2011
Row Crops
    Traits under
development
    Traits only     Global     High yields;
stress tolerance;
productivity on
marginal land
    Multiple field
evaluations of lead
traits scheduled for
2011 and 2012 in
Asia
                               
 
Subject to receipt of necessary governmental registrations, which we expect to receive in the fourth calendar quarter of 2011.
 
** Final list of commercial hybrids to be determined
 
+ NUE = nitrogen use efficiency; WUE= water use efficiency
 
Sweet Sorghum
 
Sweet sorghum is a type of sorghum that accumulates free sugars in its stalk much like sugarcane. It is sown by seed, grows faster than sugarcane, and typically requires substantially less water and nitrogen fertilizer than sugarcane to grow to harvestable maturity. Sweet sorghum plants can be harvested in 90 to 140 days after sowing compared to 12 to 18 months for sugarcane. Because sweet sorghum is an annual crop, multiple harvests or crop rotations may be possible during the season compared to sugarcane, a perennial crop. This flexibility allows mill operators to use existing land more efficiently. In general, yields of fermentable sugars from improved sweet sorghum hybrids are comparable to sugarcane during our targeted harvesting period; however, the sugary juice is not well-suited to crystalline table sugar production today. We believe that, based on our internal results and data from Brazil’s Ministério da Agricultura, Pecuária e Abastecimento, sweet sorghum yields in Brazil can range from 25 to 100 wet metric tons per hectare with sugar content, or juice Brix


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values, from 10% to 20% today. This compares to typical values for sugarcane of 50 to 90 wet tons per hectare on average, and juice Brix values ranging from 14% to over 20%.
 
In Brazil, sweet sorghum can be planted from October through January, and harvested from February to May, or later if conditions permit. This complements sugarcane, which is grown year-round, but harvested from April to December depending on weather and market conditions. In practice, sweet sorghum juice is extracted through crushing in existing sugarcane equipment, and then fermented to fuel. The leftover biomass, called bagasse, is combusted for biopower like sugarcane bagasse. Because sweet sorghum plants mature more quickly than sugarcane, and reach optimal sugar levels at different times of the year, existing sugar-to-ethanol mills can extend their operational season through the use of our sweet sorghum product by approximately 60 days. We also believe that sweet sorghum will facilitate the geographic expansion of sugar-based ethanol production into areas where sugarcane is not well adapted; for instance, where there is insufficient rainfall for sugarcane. Sweet sorghum is also advantageous during the scale up of new facilities because its seeds can be planted quickly and it has a shorter growing cycle than sugarcane. In contrast, sugarcane requires a laborious process to plant cuttings and, due to a low multiplication factor, typically requires years to provide sufficient feedstock for a mill to operate at full capacity. Therefore, we believe that sweet sorghum can enable new or expanded mill facilities to avoid long lead times or operate at their designed capacity during their first few years of operation.
 
Historically, sweet sorghum has received less improvement through modern breeding or biotechnology compared to commodity crops such as corn or soybean. Existing varieties were not developed for bioenergy, and generally have low-to-moderate sugar levels, are slower growing and have lower biomass than high biomass types. We are developing a number of improved sweet sorghum hybrids with high sugar content for immediate use in both existing markets in Brazil as well as new markets in the United States and elsewhere. In Brazil, we established agronomy trials throughout major ethanol production areas with mills, including ADM do Brasil Ltda., Usina Rio Pardo S.A. and Boa Vista/Nova Fronteira, a joint venture of Grupo São Martinho, S.A. and Petrobras Biofuels. Most notably, Boa Vista/Nova Fronteira recently planted, harvested and processed a large-scale planting of our sweet sorghum products, and produced both ethanol and power. These trials help us identify the best varieties and traits for different local conditions. They also allow us to better understand how different cultivation practices impact harvest, transportation and processing parameters. Based on the results of these trials, we plan to select our best performing seed varieties for sale during the 2011-2012 season in Brazil.
 
Concurrently, we are developing, through marker-assisted breeding and biotechnology, a succession of improved hybrids and traits that offer producers increased yields, better pest management and greater tolerance to environmental stress, among other features. Since sweet sorghum is a fast-growing annual crop, with multiple breeding cycles possible each year, we believe that product development cycles will outpace improvements that can be made in sugarcane. It is much more efficient to breed sweet sorghum varieties and hybrids than commercial sugarcane varieties and hybrids, which suffer from chromosomal instability and other factors that slow the pace and increase the complexity of making improvements through plant breeding and biotechnology.
 
High Biomass Sorghum
 
High biomass sorghum is a type of sorghum which is primarily developed for enhanced biomass yield potential as opposed to sugar content. As such, high biomass sorghum is ideally suited for the generation of renewable electric power and the creation of cellulosic biofuels. Like other types of sorghum, high biomass types are seed propagated, and generally require less water and nitrogen fertilizer than corn. As an annual crop, sorghum is harvested the year it is planted. This provides bioenergy facilities with a quick growing and flexible source of biomass, and a complementary feedstock to perennials, such as sugarcane, which may require 12 to 18 months before the first harvest, or switchgrass, which may require 12 to 24 months before the first harvest.


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In 2009, we introduced our ES 5200 and ES 5201 products that contain our Skyscraper trait. These hybrids, developed through our partnership with Texas A&M University, are designed for single-cut production systems that endeavor to maximize per-acre yields while minimizing crop input and management expenditures. Using marker-assisted breeding, we expect to develop and commercialize sorghum hybrids that offer additional increases in biomass. We are also developing hybrids with biotech traits that offer increased yield, greater tolerance to environmental stress and enhanced processing characteristics. We expect to field trial our nitrogen use efficiency and high biomass biotech traits in sorghum under our ARPA-E grant project in 2012.
 
Switchgrass
 
Switchgrass is a perennial grass indigenous to North America that tolerates a wide range of environmental conditions and offers high biomass yield potential compared to many other perennial grasses and crop plants. It generally requires substantially less water and nitrogen fertilizer than corn, and can grow under semi-arid conditions. Like sorghum, switchgrass is seed propagated. As a perennial, switchgrass is generally not harvested for sale during the first year when the crop is being established. A properly managed stand of switchgrass may persist for a decade. However, we believe that producers will likely choose to upgrade to a new variety in approximately 5 to 7 years as new generations of switchgrass seeds with even higher yields or more desirable characteristics become available.
 
From 2009 to 2010, we introduced three proprietary products: EG 1101, EG 1102 and EG 2101. These high-yielding varieties, developed through our partnership with The Samuel Roberts Noble Foundation, have demonstrated higher biomass yields on average over comparable varieties depending on the variety and trial location. EG 1101 and EG 1102 have also shown improved establishment characteristics and better disease resistance when compared to the next best public varieties. Since switchgrass has been subjected to fewer breeding efforts than most commodity crops, we believe that rapid and significant improvements can be made through advanced plant breeding and biotechnology. Current yield increases observed in our breeding program support this view. We plan to introduce a succession of enhancements to our product portfolio, including additional increases in biomass yield and other agronomic and compositional improvements. We are currently field-testing biotech traits that improve nitrogen use efficiency and biomass yields. We are also field-testing drought-tolerance traits and traits that regulate floral development. We believe that switchgrass revenue will ultimately consist of both seed sales as well as annual trait fees.
 
Miscanthus
 
Miscanthus x giganteus is a tall perennial grass that grows well in cooler climates. Unlike switchgrass and sorghum, it is vegetatively propagated. It has been used as an energy crop on a small scale across Europe for two decades. The Miscanthus genus includes several perennial species that have potential as dedicated energy crops. The variety adopted in the United States and Europe to date, miscanthus x giganteus, is a sterile hybrid of M. sinensis and M. sacchariflorus. While biomass yields for this variety may exceed those of switchgrass within its region of adaptation, we estimate that, due to its vegetative propagation system, very large-scale production is not commercially feasible at this time since establishment costs are as much as 10 times higher than seed-sown switchgrass or sorghum.
 
In general, this miscanthus hybrid requires about the same water as corn, but up to two-thirds less nitrogen depending on crop management practices. As a perennial crop, miscanthus is generally not harvested for sale during the first year when the crop is being established. The focus of our work in miscanthus is to develop seed-propagated varieties that have the same high-yielding attributes of giant miscanthus, yet with establishment costs more comparable to other energy crops. We are also working on extending the region of adaptation. To these ends, we are collaborating with the Institute of Biological, Environmental, and Rural Sciences of Aberystwyth University in Wales, U.K. Under this collaboration, we have characterized miscanthus accessions across the native range of these species.


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These accessions are currently under evaluation for plant performance in multiple locations. The highest performing lines have been entered into our breeding program. As with switchgrass, we believe that continued germplasm improvement through marker-assisted breeding will increase biomass yield, bioenergy conversion yield and agronomic performance. We are also developing miscanthus with biotech traits that have been validated in switchgrass, rice and a model test plant. We are establishing field trials of our nitrogen use efficiency and high biomass traits in miscanthus in four states under our ARPA-E grant project, and also a joint U.S. Department of Energy and U.S. Department of Agriculture Biomass R&D Initiative, or BRDI, grant.
 
Row Crops
 
Due to the conservation across species of mechanisms underlying traits, other crops can benefit from many of the biotech traits developed for energy crops. This provides us with an additional outlet for our technology and genes, and mitigates the cost and risk of trait development. By combining these genes into a series of stacks, we believe we may be able to make gains in the productivity in many row crops, such as corn, soybean, rice and wheat. Given the number of entrenched competitors in these markets and the high barriers to entry, we have chosen to be a technology provider or a trait provider to companies in this sector, rather than a direct producer of seeds.
 
We have already generated many biotech traits specifically for cereal crops such as rice that increase grain yields and provide greater yield stability across environments. We have genes that increase the number of seeds in a panicle (flower head), increase the filling of the seeds, and increase the seed yield per unit shoot mass (harvest index). Some of these have demonstrated double-digit yield increases, relative to average annual yield improvements for grain of approximately 1% as reported by Economic Botany. We also have a number of genes that make rice plants early flowering and smaller, or later flowering and larger. These flowering-time genes can increase grain yields as well. Flowering-time traits are important for rice breeders since growing season lengths vary widely among different rice cultivation regions. We have also identified genes in rice that reduce lodging and provide more efficient hybrid production systems. We are moving these and other traits into commercial rice varieties and plan to trial them in multiple locations in Asia this year.
 
Seed Production and Operations
 
Seed companies typically develop and produce three types of commercial seed and plant lines: inbred, open-pollinated and hybrid. Inbred lines maintain the characteristics indigenous to the specific parent line over many generations. Open-pollinated products are reproduced from a group of plants. These are often populations of plants that are significantly different and vary over generations. Hybrid seeds, called the F1 generation, are the first-generation progeny of two different and distinct parental lines. These seeds often possess the hereditary characteristics of the parent lines as well as enhanced performance characteristics over the parent lines due to a genetic phenomenon called “hybrid vigor”. However, subsequent generations from hybrid seeds will not inherit equivalent enhanced performance characteristics of the hybrid F1 seed. Therefore, growers of hybrid crops generally purchase new seed from seed companies for each new planting.
 
The production of commercial-scale quantities of seeds requires the multiplication of seeds through a succession of plantings and seed harvests, and if the product is a hybrid, it is produced from parent lines that are mated under controlled conditions to produce commercial hybrid seeds. For perennials, like switchgrass, an established stand can produce saleable seed for multiple years. Annual seed crops like sorghum are planted for each seed harvest. In our experience, one acre of sorghum seed production has yielded saleable seed for 500 acres of commercial production, depending on the hybrid parents, and growing conditions. In our experience, one acre of switchgrass seed production has yielded saleable seed to plant approximately 80 acres of commercial production, depending on the variety and growing conditions. We are developing ways to increase seed yields and enhance seed quality, and have already made significant gains. In addition, in switchgrass, we have developed agronomic practices that allow us to harvest seed during the same planting year, thus


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making it possible to produce seed up to 12 months sooner than with common production techniques. We believe that these improvements provide us with a competitive advantage in terms of both quality and also lower costs per unit than other seed and vegetative propagation systems.
 
We produce commercial seed either on leased land managed by us or with contract seed producers. Our current production sites are located in the United States and Puerto Rico as well as Argentina, Bolivia and Brazil. Seed production sites in both the northern and southern hemispheres allow us to schedule planting on a year round basis and reduce inventory requirements. This capability also enables us to scale up inventory to meet demand for a new product in the opposing hemisphere. During the season, we inspect seed fields for quality and anticipated seed yields. When ready, seeds are harvested using specialized techniques, cleaned, quality tested and packaged prior to sale to the customer. Healthy seed can remain saleable for several years if stored under optimal conditions.
 
In 2009, we purchased a 46,000 sq. ft. facility on a 32-acre parcel in Amarillo, Texas to serve as a seed warehouse and order fulfillment center. This site is used to receive, condition, treat, package, and warehouse our sorghum and switchgrass seed grown in the northern hemisphere. We currently warehouse and process 300,000 pounds of seed annually and anticipate that we will be able to warehouse and process up to 10 million pounds of seed annually at this facility. In Brazil, we contract seed conditioning, packaging warehousing and order fulfillment services to support our trialing and commercialization activities. We plan to add a dedicated Ceres seed facility in South America in the near future.
 
Sales and Marketing
 
We market our seed varieties and traits under the trade name Blade Energy Crops, or Blade. We are positioning Blade in the marketplace as a premium brand that represents the latest technology in energy crops. As a result, we price our proprietary products based on their added value, and not on production costs. Our seed prices are determined based on a series of complex considerations, including the best alternative use of land and perceived added value to growers and mill owners. Our pricing philosophy is to share a portion of the added value we create with our customers.
 
To gain greater brand awareness, we actively promote our products, capabilities and brand to the bioenergy and agricultural industries. In the United States, in addition to our direct relationship with bioenergy companies and project developers, we take a leading role in teaching the grower community about energy crops and related agronomic systems through the publication of crop management guides, speaking roles at industry events, trade show displays and local-level grower meetings. We also use these opportunities to build brand awareness and loyalty.
 
We sell and distribute our seed products directly to our customers, which include ethanol mills, utilities, independent power producers, cellulosic biofuel companies, individual growers and grower cooperatives. We also work with technology providers and other industry participants such as equipment manufacturers, enzyme or fermentation technology companies, to encourage the use of our products. We believe that, compared to the corn or soybean seed industry, our sales force can be significantly smaller due to the more consolidated nature and more vertically integrated business models of the bioenergy industry.
 
We are building our customer base primarily by forming collaborations with biorefineries, power generators and biomass users at their existing, planned and future facility locations. We are in active discussions with a number of Brazilian ethanol producers for the 2011-2012 season in Brazil. In the United States, our seed sales to date have been driven primarily by pilot and demonstration-scale projects with advanced biofuel and biopower companies as well as growers and grower associations. Typically these multi-year collaborations include agronomy trials, harvest and handling evaluations, test conversions or burns, and various post-harvest assays. In addition to informing our market development and research efforts, these trials allow participants in the value chain to gain confidence with the yields and other performance characteristics they should expect to see from our products. We believe that our expertise in feedstock performance and production practices across many growing


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regions, combined with our extensive relationships throughout the bioenergy value chain, is a key competitive advantage.
 
In Brazil, we market and sell our sweet sorghum products directly to ethanol mills, rather than to growers, which is the prevailing practice in the seed industry, as mill operators typically manage all major aspects of feedstock selection and production. Given the close-knit nature of the ethanol industry in Brazil, we believe that successful trials with several large mills will encourage other operators to evaluate and adopt our sweet sorghum products. We have ongoing trials with a number of large mill operators, including ADM do Brasil Ltda., Usina Rio Pardo S.A. and Boa Vista/Nova Fronteira, a joint venture of Grupo São Martinho, S.A. and Petrobras Biofuels. We also have collaborations with international companies active in Brazil, including Amyris Biotechnologies, Inc. and Novozymes North America, Inc.
 
In the biopower market, our current activities encompass field trials, test burns and sales of commercial seed to project developers and growers who sell or intend to sell biomass to power plants or pellet mills. In the United States, we have worked on a trial basis with major utilities and large industrial producers of heat and power. We are also helping European utilities identify U.S. suppliers of biomass produced from our dedicated energy crops.
 
Our activities in cellulosic biofuels encompass a wide range of activities including field trials, co-evolution agreements, and commercial sales. Our products have been tested in the respective conversion processes of EdeniQ, Inc., Choren USA LLC, Gruppo M&G, ICM, Inc., and UOP, LLC (a Honeywell company), among others. DDCE also plans to validate our products in their conversion process. We have also conducted joint trials with, or sold seed to, AGCO Corporation, EdeniQ, Inc. and Hawai’i BioEnergy, LLC, among others. We recently began a collaboration with Valero Services, Inc. to further evaluate feedstock supply strategies with dedicated energy crops. We also work with refining technology companies to optimize feedstock for their refining processes. These collaborators include Novozymes North America, Inc. and ThermoChem Recovery International, Inc.
 
Major Research Collaborations
 
Monsanto Company
 
In April 2002, we entered into a multi-year discovery and development collaboration with Monsanto Company focused on applying genomics technologies to identify genes that provide improvements in corn, soybean and certain other row crops. Pursuant to this agreement, Monsanto licensed rights to a portion of our trait discovery pipeline in certain row crops in exchange for license payments over several years. Monsanto also funded a research program with us. We believe the $137 million transaction with Monsanto validated our technology platforms and provided us a channel to begin to deploy our traits into corn, soybean and other commodity crops. We remain free under this agreement to develop and commercialize the genes and traits developed under this collaboration for deployment in our energy crops and certain other crops such as rice. With respect to corn, soybean and other row crops, we are free to license some of the genes discovered during this collaboration on a non-exclusive basis to third parties. We can also develop and exclusively license to third parties genes not covered under this agreement and which we have subsequently developed for use in corn, soybean and other row crops.
 
In connection with entering into the collaboration agreement, Monsanto also purchased 3,333,333 shares of our Series E Preferred Stock.
 
The Samuel Roberts Noble Foundation, Inc.
 
In May 2006, we entered into an agreement with The Samuel Roberts Noble Foundation, Inc., a non-profit agricultural institute for the development and commercialization of switchgrass. This relationship provides us access to extensive breeding infrastructure and exclusive licenses to elite


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switchgrass varieties, breeding lines and advanced cultivars. We use our markers and other genomics technologies to expand the conventional and molecular breeding program in switchgrass at the Noble Foundation.
 
Institute of Biological, Environmental and Rural Sciences of Aberystwyth University
 
In April 2007, we entered into an agreement with the Institute of Biological, Environmental, and Rural Sciences of Aberystwyth University in Wales, U.K., or IBERS, for morphological characterization, genetic evaluation, and the development and commercialization of miscanthus species as an energy crop. This relationship provides us access to an extensive scientific research infrastructure and includes exclusive licenses to miscanthus germplasm, breeding lines and varieties produced by IBERS, except that IBERS has a non-exclusive license in the United Kingdom to varieties resulting from the joint program. We use our expertise in genomics-based technologies and plant breeding to expand the miscanthus breeding program at IBERS.
 
Texas A&M University
 
In August 2007, we entered into an agreement with The Texas A&M University System for the development and commercialization of high biomass sorghum, sweet sorghum and selected related crops as energy crops, together with the discovery of molecular markers for certain traits. This relationship provides us with access to a highly regarded sorghum breeding program and the extensive sorghum genetics, breeding and genomics infrastructure of Texas A&M University. This agreement provides exclusive options and licenses to elite sorghum breeding lines, parental lines, advanced hybrids and genomic markers.
 
Government Grant Awards
 
Grant awards help mitigate the costs and risks of developing new products and have historically allowed us to broaden the scope and speed of our research and development activities. Over the past five years, we have received several grants from the DOE, the USDA, the USAID, and BRDI program as well as state-level grants. These have allowed us to investigate the use of our biotech traits for increased yield, nitrogen use efficiency, flowering regulation, improved carbon sequestration and manipulation of cell wall composition in crops. Our grant funding totaled $3.0 million in the fiscal year ended August 31, 2010.
 
Our projects funded in whole or in part by grants during fiscal year 2010-11 include:
 
  •  A $5.1 million U.S. Department of Energy ARPA-E grant to develop high biomass, low-input energy crops;
 
  •  A $3.0 million USAID grant to develop several traits in rice for Asia;
 
  •  A subcontract award of $2.2 million under a $25 million DOE Integrated Biorefinery grant awarded to Amyris Biotechnologies, Inc. to conduct multi-site trials of sweet sorghum;
 
  •  A contract of $161,000 under a $250,000 Alabama Department of Economic and Community Affairs, grant awarded to Amyris Biotechnologies, Inc. to study the viability of sweet sorghum and sugarcane;
 
  •  A $491,000 subcontract award from the DOE’s BioEnergy Science Center to field trial traits to reduce recalcitrance and improve conversion of switchgrass to biofuels;
 
  •  A subcontract award of $86,000 under a $4.7 million BRDI grant to the University of Tennessee together with DuPont Danisco Cellulosic Ethanol LLC to plant 1,000 acres of switchgrass to investigate agronomy and biomass supply chain logistics;
 
  •  A $883,000 BRDI grant with Choren USA, LLC, a biorefining company, to investigate desirable biomass compositional characteristics for biomass gasification;


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  •  A $1.5 million BRDI grant with Rohm & Haas (now part of Dow Chemical) to investigate the production of methacrylate as a co-product in switchgrass; and
 
  •  A contract of $22,000 under a $25 million DOE Integrated Bio-Refinery, or IBR, grant to UOP, LCC, a Honeywell company, to build a demonstration unit in Hawaii to convert cellulosic biomass into renewable transportation fuels.
 
Intellectual Property
 
Our success depends in large part on our proprietary products and technology for which we seek protection under patent, plant variety protection, plant breeders’ rights, copyright, trademark and trade secret laws. Protection of products, technology and trade secrets is also maintained using confidential disclosure agreements entered into by our employees, consultants and potential and actual third party collaborators. Protection of our technologies enables us to offer our customers and partners proprietary products unavailable from our competitors, and to exclude our competitors from practicing technology that we have developed or exclusively licensed from other parties. If competitors in our industry have access to the same technology, our competitive position may be adversely affected.
 
We believe that we have established a broad intellectual property position in plant genes, traits and energy crop germplasm. As of April 30, 2011, we owned or had exclusive licensed rights to approximately 110 issued patents and approximately 200 pending patent applications in the United States and in various foreign jurisdictions. The patents for Ceres-developed inventions are set to expire beginning in 2020. Our patents or patent applications generally relate to compositions of matter for DNA and protein sequences, plants and plant parts, and methods of improving plants. Our patents and applications encompass more than 100,000 full-length, functionally annotated cDNA sequences from several species, hundreds of gene-trait associations, and hundreds of characterized promoters with specialized expression patterns. In addition, we hold dozens of applications for patents, Plant Variety Protection certificates and plant breeders’ rights for our commercial varieties, hybrids and inbreds, as well as for methods for the improvement, propagation, production, and use of dedicated energy crops. We continue to file new patent applications, for which terms generally extend 20 years from the filing date in the United States. Our registered and pending trademarks in the United States and in selected foreign countries include Ceres, The Energy Crop Company, Blade Energy Crops, Blade and Skyscraper.
 
We will continue to file and prosecute patent, Plant Variety Protection certificate, plant breeders’ rights, and trademark applications in the United States and foreign jurisdictions, as well as maintain trade secrets as is consistent with our business plan in an ongoing effort to protect our intellectual property.
 
Competition
 
The renewable energy industry is rapidly evolving and new competitors with competing technologies are regularly entering the market. We expect to face competitors on multiple fronts. First, we expect to compete with other providers of seed and vegetative propagation materials in the market for sweet sorghum, high biomass sorghum, switchgrass and miscanthus. While the competitive landscape in these crops is limited at this time, we anticipate that as our products gain market acceptance, other competitors will be attracted to this opportunity and produce their own seed varieties. Second, we believe that new as yet unannounced crops will be introduced into the renewable energy market and that existing energy crops will attempt to gain even greater market share. Existing crops, such as corn, sugarcane and oil palm trees, currently dominate the biofuels market. We believe the primary competitive factors in the energy crop seed industry are yield, performance, scale, price, reliable supply and sustainability. As new products enter the market, our products may become obsolete or our competitors’ products may be more effective, or more effectively marketed and sold, than our products. Changes in technology and customer preferences may result in short product life cycles. To


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remain competitive, we will need to develop new products and enhance and improve our existing products in a timely manner. Our failure to maintain our competitive position could have a material adverse effect on our business and results of operations.
 
Our principal competitors may include major international agrochemical and agricultural biotechnology corporations, such as Advanta India Limited, The Dow Chemical Company, Monsanto Company, Pioneer Hi-Bred (DuPont), KWS and Syngenta, all of which have substantially greater resources to dedicate to research and development, production or marketing than we have. We also face direct competition from other seed companies and biotechnology companies, and from academic and government research institutions. New competitors may emerge, including through consolidation within the seed or renewable energy industry. We are unable to predict what effect evolution of the industry may have on price, selling strategies, intellectual property or our competitive position.
 
In the broader market for renewable energy, we expect to face competition from other potential feedstocks, including biomass residues from food crops, forestry trimmings and municipal waste materials as well as other energy crops. There are multiple technologies that process biomass into biofuels and we have yet to determine compatibility of our feedstocks with all of these processes. Our failure to develop new or enhanced products that are compatible with these alternative technologies, or a lack of market acceptance of our products as the common denominator in a broad array of bio-based products that are alternatives to petroleum based products, could have an adverse effect on our business. Significant developments in alternative technologies, such as the inexpensive and large-scale storage of solar or wind-generated energy, may materially and adversely affect our business in ways that we do not currently anticipate.
 
We believe the primary competitive factors in the energy crop seed industry are yield, performance, scale, price, reliable supply and sustainability. As new products enter the market, our products may become obsolete or our competitors’ products may be more effective, or more effectively marketed and sold, than our products. Changes in technology and customer preferences may result in short product life cycles. To remain competitive, we will need to develop new products and enhance our existing products in a timely manner.
 
Government Policies and Incentives
 
There are numerous mandates, incentive programs, tax credits, support schemes and pending legislation that impact the establishment and growth of bioenergy markets. Some of the most relevant to our near term business opportunities are highlighted below:
 
Renewable Fuel Standard 2 — The U.S. Energy Independence and Security Act of 2007, or EISA, increased the volume of renewable fuel required to be blended into transportation fuel to 36 billion gallons per year by 2022, representing an increase of 27 billion gallons from the 2008 target level of 9 billion gallons. EISA also established new categories of renewable fuel and set separate volume requirements for each one, including a 16 billion gallon per year target by 2022 for cellulosic biofuels. While these targets have been adjusted periodically to take into account cellulosic production capabilities, we believe this target demonstrates the U.S. commitment to significantly expand its use of cellulosic fuels. EISA required Environmental Protection Agency to apply lifecycle greenhouse gas performance threshold standards to ensure that each category of renewable fuel emits fewer greenhouse gases than the petroleum fuel it replaces.
 
Biomass Crop Assistance Program, or BCAP — Established by the 2008 U.S. Farm Bill, BCAP provides risk mitigation and production incentives to encourage growers to produce dedicated energy crops. BCAP provides two categories of assistance: (i) matching payments at a rate of $1 for each $1 per dry ton paid by a qualified biomass conversion facility, in an amount up to $45 per dry ton, for a period of 2 years, and (ii) establishment payments up to 75% of costs of establishing a qualified perennial crop, including the cost of seed and stock, to growers who enter into contracts with the Commodity Credit Corporation, or CCC, to produce eligible biomass crops on contract acres within BCAP project areas. Annual payments, which are


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determined by CCC and based on local land rental rates, are also available for both annuals and perennials. Such payments are reduced if the biomass is sold to a conversion facility. We believe that BCAP will be advantageous to the growth of the switchgrass and miscanthus markets, in particular. The program will expire in 2012, unless extended as part of the next Farm Bill.
 
Renewable Electricity Standard — Twenty-nine states plus the District of Columbia have Renewable Electricity Standards (also known as Renewable Portfolio Standards or RPS); seven additional states have voluntary goals. There is no federal standard currently. States with renewable portfolio standards require that a certain percentage (or absolute amount) of electricity be generated from renewable sources by a specified date. Under existing state regulations, these standards range from 8% to 40% of electricity production. To comply, companies must typically own a qualified facility and its output, purchase renewable energy credits or purchase bundled renewable electricity. Contracted, closed-loop biomass is an eligible renewable feedstock in all states with RPS.
 
Renewable Energy Production Tax Credit, or PTC — Originally enacted by the U.S. Energy Policy Act of 1992, and updated by the American Recovery and Reinvestment Act of 2009, the PTC provides federal tax incentives for renewable energy projects. In general, the PTC reduces the federal income taxes of qualified tax-paying owners of renewable energy projects based on output. In 2010 the credit ranged from 1.1 to 2.2 cents per kilowatt-hour. Currently, a full PTC is available to dedicated biomass-fired facilities utilizing 100% closed-loop biomass, which is biomass grown exclusively for energy. A half-PTC is available for dedicated biomass-fired facilities utilizing open-loop biomass and other biomass sources, usually waste materials. The PTC is not available for co-firing coal with open-loop biomass, but it is technically available for co-firing closed-loop biomass with coal or open-loop biomass. We believe our customers can utilize our products to produce closed-loop biomass, thereby taking advantage of these tax credits to improve the economics of their operations. However, due to a legislative error, new PTC applications for co-firing with closed-loop biomass, whether with coal or in a dedicated biopower facility with open-loop biomass, cannot be approved since the approving agencies no longer exist despite multiple extensions of the biomass option by Congress and an existing federal budget line item for the program. We have joined utility industry representatives in lobbying Congress for new legislation to correct the error.
 
Renewables Obligation Certificates — The United Kingdom, which is a potential export market for U.S.-grown biomass, favors biomass from energy grasses in its renewable electricity mandates. Renewables Obligation Certificates, or ROCs, are issued for each megawatt hour, or MWh, of renewable electricity generated. These ROCs are tradable. Compliance can be achieved by acquiring ROCs from generation or purchase, or paying a buy-out price. On March 29, 2011, the average price for ROCs was £49.89. ROCs are earned at various rates, with different categories of generation receiving a different number of ROCs per MWh generated. Co-firing of non-energy crop biomass, for instance, currently receives 0.5 ROCs/MWh, while a full ROC/MWh is earned from co-firing of contracted, closed-loop sources of biomass as well as open-loop sources of pre-approved crops, such as miscanthus. Switchgrass and high biomass sorghum are currently under review as possible pre-approved feedstocks. These rates and categories are subject to ongoing review by regulators. We believe that this regulatory scheme, especially when paired with U.S. incentive programs, provides attractive economics for U.S. growers with nearby access to seaports.
 
Regulatory Matters
 
Some of our products and operations are subject to complex regulations.


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U.S. Regulatory Process for Our Biotechnology Products
 
Under the Plant Protection Act of 2000, regulatory approval is required before the introduction, including the environmental release, interstate movement, and importation, of certain genetically engineered organisms, including our biotechnology products. The primary U.S. regulatory agency overseeing field testing and deregulation for commercialization of our biotechnology products is the United States Department of Agriculture, or USDA. Currently, our products do not include pesticide or herbicide tolerant traits and, consequently, do not require the involvement of the Environmental Protection Agency. Moreover, our products are not intended for food or animal feed uses and, consequently, do not require the involvement of the Food and Drug Administration. The Biotechnology Regulatory Services, or BRS, within the USDA’s Animal and Plant Health Inspection Service, or APHIS, has direct oversight of the field testing and deregulation of our biotechnology products.
 
In the typical product development process for our biotechnology products, approval by APHIS initially is required for field testing of a new product. Field testing of our biotechnology products is subject to a rigorous permit process that, if successful, results in authorization by APHIS for a defined field testing period in a specific location. As of April 30, 2011, we have been granted permits for field trials of certain of our biotechnology products in development in four field test locations, located in Arizona, Georgia, Tennessee and Texas. We are currently trialing, or intend to trial, several traits in switchgrass, miscanthus and sorghum.
 
The permit application must contain detailed information about the product, including a description of the inserted genes, their origin, the purpose of the test, how it will be conducted and any actions taken to prevent the release of pollen or seed from the test site. In determining whether to grant a permit and what conditions to impose, APHIS considers any possible impacts of the field test on the environment and any endangered or threatened species. The permitting process for the establishment of initial field tests typically ranges from two to four months, but can be significantly longer for novel products or circumstances.
 
We must petition APHIS to deregulate any of our biotechnology products before being able to commercialize the product. The petition process is a multi-year process that varies based on a number of factors, including the extent of the supporting information required, the nature and extent of review by APHIS, including the type and scope of the environmental review conducted, and the number and types of public comments received. Deregulation of a product is not a guaranteed outcome when a petition to deregulate a biotechnology plant is submitted to APHIS.
 
The process for obtaining favorable action on petitions for non-regulated status, as well as permits for field testing, has become more complex and time consuming in recent years. In October 2008, APHIS issued proposed regulations that would significantly revise the permitting process; however whether or when APHIS will issue final regulations is not known.
 
We are a founding member of the Excellence Through Stewardship, or ETS, organization, which encourages implementation of biotechnology-derived product stewardship practices, including third-party audits of members to verify that stewardship programs and quality management systems are in place and consistent with ETS initiative. We successfully completed our initial ETS third-party audit in December 2009. We continue to conduct yearly internal audits and a third-party audit every three years.
 
Brazilian Regulatory Process for Our Biotechnology Products
 
In Brazil, the approval of biotechnology products is regulated by the National Technical Commission of Biosafety, Comissão Técnica Nacional de Biossegurança, or CTNBio, under the Ministry of Science and Technology. CTNBio is composed of 27 members with specialists with scientific and technical knowledge from four different areas, including specialists in animal, plant, environment and health (12 members), ministerial representatives of the federal government (9 members) and specialists from other areas such as consumer defense and family farming (6 members) that meet once per month to review applications. CTNBio has developed guidance describing the information required as


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part of an application for commercial approval of a biotechnology product. Once an application is submitted it is analyzed by a team of reviewers who then present the application to the broader committee for a decision. The review team or the committee can request additional information from the applicant. The application process is generally an iterative process with the applicant providing additional data for review and consideration at subsequent monthly meetings until all the reviewers’ and the committee’s questions have been resolved. During the review process, CTNBio will evaluate the need for further environmental impact assessments. CTNBio may conduct public hearings on certain products to seek additional input. CTNBio may refer applications to, among others, the National Biosafety Council, or CNBS, to review any socio-economic aspects or national interests that may be implicated. We are not currently subject to CTNBio oversight as our current product offerings in Brazil do not include biotechnology products. However, we do anticipate introducing biotechnology products in Brazil in the future. At such time, we will be subject to the approval processes dictated by CTNBio and a Certificate of Quality in Biosafety, or CQBs, must be obtained from CTNBio prior to the commencement of field trials.
 
Other Regulation
 
Phytosanitary Certification.  Nearly all countries, including the United States and Brazil, and many local jurisdictions, require phytosanitary certificates to import seed or plant materials. These certificates, issued by government agricultural inspectors where seeds or plants are produced or packaged, attest that seeds or plants are clean, free of prohibited impurities and have been tested for the presence of various pathogens that can be carried in or on the seeds or plant tissue. We obtain such certificates when necessary, including in connection with the use of our seeds for research or sample testing.
 
Seed and Plant Variety Registration.  Seed and plant variety registration provides an organized system for protecting seed and plant variety owners as well as growers from misleading marketing practices. Registration of seed and plant varieties is voluntary in the United States under the Federal Seed Act. Applicants must attest that their product is phenotypically unique; that is, verifiably different from varieties that currently exist in the market. A similar system exists in Brazil, the European Union and many other countries; however, the registration process itself may be more regulated, and is sometimes required prior to the commencement of seed sales. In Brazil, sweet sorghum requires two seasons of trial data to be registered, which must be completed prior to the commencement of sales. We have completed our first season of trial data and are substantially complete with the second season of trial data. We expect to submit our application for registration of our non-biotech sweet sorghum varieties in Brazil in the second half of 2011. Similarly, in the European Union, two years of field trials with a national authority are required to receive registration for all member states. Registration is required prior to the commencement of sales for new high biomass sorghum and sweet sorghum seed varieties; there is no registration requirement for switchgrass or miscanthus at this time.
 
Regulation of Laboratory and Greenhouse Facilities.  The use of genetically engineered organisms in laboratory and greenhouse facilities is subject to rules intended to ensure that such organisms are handled safely and do not pose an unacceptable risk to human health or the environment. The National Institute of Health’s Guidelines for Research Involving Recombinant DNA Molecules, or the NIH Guidelines, describe methods for the safe handling of transgenic materials in laboratory settings. Appendix P (Physical and Biological Containment for Recombinant DNA Research Involving Plants) of the NIH Guidelines describes specific requirements for facilities and practices to meet containment standards for each of the different biosafety levels from lowest containment (designated BL1-P) through the highest containment (designated BL4-P). Appendix P is also used as a guideline for practices relating to conducting experiments to construct, develop, and propagate genetically engineered plants. Our current biosafety level is BL1-P, which requires a low level of containment for experiments involving our biotechnology plants.
 
Hazardous Materials.  Our laboratory and field activities inherently involve the use of potentially hazardous materials, which are subject to health, safety and environmental regulations. Our infrastructure, procedures and equipment are designed to meet our obligations under these regulations. We


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perform recurring internal and third-party audits and provide employees ongoing training and support, as required. All employees must comply with safety instructions and procedures, which are codified in our employment policies.
 
Employees
 
As of April 30, 2011, we had approximately 88 full-time employees. Of these employees, approximately 58 were engaged in research and development. Our employees are located in the United States and Brazil. We consider our employee relations to be good. None of our employees are represented by a labor union or collective bargaining agreement.
 
Facilities
 
Headquarters
 
Our headquarters is located in Thousand Oaks, California, where we lease approximately 49,000 square feet of office, laboratory and greenhouse space. The lease expires on March 31, 2014. We have one option to extend the lease for an additional term of five years, provided that we give notice to the landlord at least six months prior to the expiration of the initial term of the lease.
 
College Station Research Center
 
Our plant breeding and field research center is located in Burleson County near College Station, Texas. Completed in 2009, the site consists of approximately 12,000 square feet of office, laboratory, warehouse and greenhouse space. The research center sits on approximately five acres of leased land, which we hold the option to purchase. Adjacent to our facility, we also lease approximately 200 acres of farmland under a five-year lease expiring in 2013, with two options to extend this lease by five years each.
 
Amarillo Operations
 
Our primary U.S. seed warehousing, conditioning, packaging and order fulfillment facility is located in Amarillo, Texas. Purchased in 2009, the site consists of approximately 46,000 square feet of office and warehouse space on a 32-acre parcel. We currently warehouse and process 300,000 pounds of seed annually and anticipate that we will be able to warehouse and process up to 10 million pounds of seed annually at this facility.
 
Brazil
 
We lease an office located in the Municipality of Piracicaba, São Paulo, Brazil. We have an option to extend the lease for an additional term of five years. We also have an option to purchase the property. The lease expires on December 31, 2011. While we currently contract seed warehousing, conditioning, packaging and fulfillment services to support our trialing and commercialization activities, we expect to add a dedicated Ceres breeding and seed production facility in South America.
 
We believe that our facilities in California, Texas and Brazil, including our planned breeding and seed production facility in South America, will adequately meet our needs in the near term.
 
Legal Proceedings
 
We are not currently a party to any material litigation or other material legal proceedings.


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MANAGEMENT
 
Executive Officers and Directors
 
The following table sets forth information regarding our executive officers, directors and key employees as of May 1, 2011.
 
             
Name
 
Age
 
Position
 
Board of Directors:
           
Walter De Logi, Ph.D.(1)(2)
    60     Chairman of the Board
Pascal Brandys(2)
    52     Director
Raymond Debbane
    56     Director
Ruth Devenyns
    46     Director
Richard Flavell, Ph.D. 
    67     Director, Chief Scientific Officer
Robert Goldberg, Ph.D.(2)
    66     Director
Richard Hamilton, Ph.D. 
    48     Director, President and Chief Executive Officer
Thomas Kiley(1)
    68     Director
David B. Krieger
    37     Director
Edmund Olivier(1)(2)
    73     Director
Gerard Van Acker
    67     Director
Other Executive Officers and Key Employees:
           
Paul M. Kuc
    49     Chief Financial Officer
Wilfriede van Assche
    56     Senior Vice President, General Counsel and Secretary
J. Jefferson Gwyn, Ph.D. 
    52     Vice President of Breeding and Genomics
Michael Stephenson
    68     Vice President of Operations
Roger Pennell, Ph.D. 
    51     Vice President of Trait Development
 
(1) Member of Audit Committee
 
(2) Member of Compensation Committee
 
(3) Member of the Nominating and Governance Committee
 
Our executive officers are elected by, and serve at the discretion of, our board of directors. There are no family relationships among any of our directors and executive officers.
 
Board of Directors
 
Walter De Logi, Ph.D., Chairman of the Board
 
Dr. De Logi is one of the founders of Ceres and served as our President and Chief Executive Officer from the founding of the Company in 1996 until September 2002. Dr. De Logi has served on our board of directors since our inception. From 1986 to 1996, he was the Chief Executive Officer of Plant Genetic Systems, an eminent first-generation plant biotechnology company that was sold to Hoechst Schering AgrEvo GmbH, now part of Bayer AG in 1996. He holds an M.B.A. from Harvard University and a Ph.D. from the California Institute of Technology. Dr. De Logi was nominated to serve on our board of directors pursuant to the terms of the Voting Agreement. Dr. De Logi brings extensive experience in the plant biotechnology business to the board of directors.
 
Pascal Brandys, Director
 
Mr. Brandys has served on our board of directors since December 1997. Mr. Brandys is the President of Biobank Technology Ventures, LLC, an early-stage life sciences investment company which he co-founded in 2001. He was previously a co-founder of the genomics company Genset S.A., and also served as its Chairman and Chief Executive Officer from 1989 to 2000. Mr. Brandys is currently a director of several private companies and previously served as a director of Ilog S.A and


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Innogenetics N.V. He holds an M.S. in Economic Systems from Stanford University and is a graduate of the Ecole Polytechnique of Paris. Mr. Brandys brings extensive business experience in the genomics field and experience as an executive and an investment professional to our board of directors.
 
Raymond Debbane, Director
 
Mr. Debbane has served on our board of directors since March 1998. Mr. Debbane is President and Chief Executive Officer of The Invus Group, LLC, a New York based multi-billion dollar investment firm which is the exclusive investment advisor of Artal Luxembourg S.A., a shareholder of Ceres. Prior to forming The Invus Group in 1985, Mr. Debbane was a manager and consultant for The Boston Consulting Group in Paris, France. He is currently a director of Artal Group S.A. and Lexicon Pharmaceuticals, Inc., as well as a number of private companies in which Artal or Invus, L.P. is an investor. Mr. Debbane is also the Chairman of the board of directors of Weight Watchers International. He holds an M.B.A. from Stanford Graduate School of Business, an M.S. in Food Science and Technology from the University of California, Davis and a B.S. in Agricultural Sciences and Agricultural Engineering from American University of Beirut. Mr. Debbane was nominated to serve on our board of directors by Artal Luxembourg S.A. pursuant to the terms of the Voting Agreement. Mr. Debbane brings extensive business and finance experience to our board of directors, as well as experience as a director of a number of companies.
 
Ruth Devenyns, Director
 
Ms. Devenyns has served on our board of directors since June 2010. Ms. Devenyns is an Investment Director at KBC Private Equity NV, a shareholder of Ceres, where she manages KBC’s investments in life sciences. She began her career with KBC in 1986, as a research analyst covering several industries including the chemical and pharmaceutical industry and held various positions with KBC during her career, including advising the Belgian government on its privatization program. In 2001, Ms. Devenyns co-launched KBC Private Equity Fund Biotech, a Euronext-listed dedicated private equity fund focused on life sciences. She is a director of FlandersBio, an organization representing the Flemish life sciences cluster. Ms. Devenyns has a Masters Degree in Applied Economics from Ghent University. Ms. Devenyns was nominated to serve on our board of directors by KBC Private Equity N.V. pursuant to the terms of the Voting Agreement. Ms. Devenyns brings extensive experience in business and finance, as well as experience as an investment professional in the life sciences industry, to our board of directors.
 
Richard Flavell, Ph.D., FRS, CBE, Chief Scientific Officer and Director
 
Dr. Flavell joined Ceres in 1998 as Chief Scientific Officer and has served on our board of directors since June 2009. He is currently an Adjunct Professor in the Department of Molecular, Cellular and Developmental Biology at the University of California, Los Angeles. From 1987 to 1998, Dr. Flavell was the Director of the John Innes Centre in Norwich, England, a premier plant and microbial research institute. He has published over 200 scientific articles, lectured widely and contributed significantly to the development of modern biotechnology in agriculture. Dr. Flavell is an expert in cereal plant genomics, having produced the first molecular maps of plant chromosomes to reveal the constituent sequences. In 1999, Dr. Flavell was named a Commander of the British Empire for his contributions to plant and microbial sciences. Dr. Flavell received his Ph.D. from the University of East Anglia and is a Fellow of European Molecular Biology Organization and of The Royal Society of London. Dr. Flavell brings extensive experience and knowledge of plant biotechnology to our board of directors.
 
Robert Goldberg, Ph.D., Director
 
Dr. Goldberg is a Distinguished Professor of Molecular, Cell and Developmental Biology at the University of California, Los Angeles and a founder of Ceres. He has been a Professor at the


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University of California, Los Angeles for the past 35 years, teaching genetic engineering and studying the genes that are required for seed formation. Dr. Goldberg is a member of the National Academy of Sciences and has consulted extensively in the agriculture and biotechnology industries. Dr. Goldberg has served as a director of Ceres since 1996. Dr. Goldberg received his Bachelor’s Degree in botany from Ohio University, his Ph.D. in plant genetics from the University of Arizona, and was a Postdoctoral Fellow in developmental biology at the California Institute of Technology. Dr. Goldberg brings extensive experience in the agriculture and biotechnology industries to our board of directors.
 
Richard Hamilton, Ph.D., President, Chief Executive Officer and Director
 
Dr. Hamilton joined Ceres in 1998. He served as our Chief Financial Officer until September 2002, at which time he was appointed President and Chief Executive Officer. He has served on our board of directors since 2002. In addition to his leadership role at Ceres, Dr. Hamilton sits on the Keck Graduate Institute Advisory Council and he is a founding member of the Council for Sustainable Biomass Production. He has served on the U.S. Department of Energy’s Biomass Research and Development Technical Advisory Committee and has been active in the Biotechnology Industry Organization where he has served as Vice Chairman of the organization, chaired its Food and Agriculture Governing Board and served in other leadership roles. From 1992 to 1997, Dr. Hamilton was a principal at Oxford Bioscience Partners, one of the leading investors in the genomics field and a founder of Ceres. From 1990 to 1991, he was a Howard Hughes Medical Institute Research Fellow at Harvard Medical School. Dr. Hamilton holds a Ph.D. in molecular biology from Vanderbilt University. Dr. Hamilton brings extensive management experience and renewable energy industry expertise to our board of directors.
 
Thomas Kiley, Director
 
Mr. Kiley has served as a director of Ceres since May 2003. He was the first general counsel of Genentech and later served as its vice president for corporate development until 1988. Previously, Mr. Kiley practiced intellectual property litigation as a partner of Lyon & Lyon. Mr. Kiley is a director of Geron, Inc., a publicly traded biopharmaceutical company and Transcept Pharmaceuticals, Inc., a publicly traded pharmaceutical company, and several privately-held development stage companies. He received his B.S. in chemical engineering from The Pennsylvania State University and his J.D. from The George Washington University School of Law. Mr. Kiley brings extensive experience as an intellectual property attorney and director of other public companies to our board of directors.
 
David B. Krieger, Director
 
Mr. Krieger has served as a director of Ceres since February 2011. Mr. Krieger is a managing director at Warburg Pincus LLC, (which through its affiliates is a shareholder of Ceres), and has been with Warburg Pincus since 2000. Prior to joining Warburg Pincus, he worked at McKinsey & Company in Atlanta and Europe. He is currently a board member of Black Swan Energy Ltd., Canbriam Energy Inc., Fairfield Energy Limited, Kosmos Energy Ltd., MEG Energy Corp. and Osum Oil Sands Corp. He received a B.S. in Economics from the Wharton School of the University of Pennsylvania, an M.S. from the Georgia Institute of Technology and an M.B.A. from Harvard Business School. Mr. Krieger was nominated to serve on our board of directors by Warburg Pincus pursuant to the terms of the Voting Agreement and brings extensive experience in business and finance and the energy industry to our board of directors.
 
Edmund Olivier, Director
 
Mr. Olivier has served on our board of directors since our inception in 1996. Mr. Olivier is a founding general partner of Oxford Bioscience Partners, one of the founders of Ceres. He has overseen investments in numerous life science companies in the United States, Europe, India and Japan. He has also served on the board of directors of a number of Oxford Bioscience’s portfolio companies. Mr. Olivier received an M.B.A. from Harvard Business School and a B.S. in Chemical


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Engineering from Rice University. He is a Life Fellow and member of the International Council of the Salk Institute and a Regent of Harris Manchester College, Oxford University. Mr. Olivier was nominated to serve on our board of directors by entities affiliated with Oxford Bioscience Partners pursuant to the terms of the Voting Agreement and brings extensive experience in business and finance, as well as an understanding of the life sciences industry, to our board of directors.
 
Gerard Van Acker, Director
 
Mr. Van Acker has served on our board of directors since April 2009. He also served on our board of directors from 1998 until 2001. From 1980 to 2000, Mr. Van Acker was Chief Executive Officer and Chairman of the Executive Committee of Gimv N.V., Belgium’s leading private equity firm and a shareholder of Ceres. Mr. Van Acker was one of the founders and vice chairman of Plant Genetic Systems, an eminent first-generation plant biotechnology company that was sold to Hoechst Schering AgrEvo, GmbH, now part of Bayer AG, until 1996. He was also the chairman of Biotech Fonds Vlaanderen until 2000. He has also held director positions in a number of leading listed Belgian companies including Barco, a global technology company, Telenet Group, a cable and phone company and Kinepolis Group. He has also been on the board of directors of VIB, a life sciences research institute in Belgium, since its inception. He is currently the Chairman of the board of directors of Montea, a listed real estate company. Mr. Van Acker holds a Doctorate in Law and a Master’s Degree in Political and Administrative Sciences from the Free University of Brussels. Mr. Van Acker was nominated to serve on our board of directors by Gimv N.V. pursuant to the terms of the Voting Agreement and brings extensive experience in business and finance to our board of directors, as well as his experience as a director of a number of other companies.
 
Executive Officers
 
Paul M. Kuc, Chief Financial Officer
 
Mr. Kuc joined Ceres in 2008 as Chief Financial Officer, following a 12-year career with Monsanto Company, where he held various regional and global finance positions, including posts in Argentina, Brazil, Canada, Mexico and the United States. At Monsanto, among other responsibilities, he developed and implemented international costing and financial systems for the seed and agricultural biotechnology company. Mr. Kuc began his career at the pharmaceutical company Eli Lilly and Company. He holds a Master’s of Science degree in Economics from the University of Lodz, Poland and an M.B.A. from the Ivey Business School, University of Western Ontario, Canada.
 
Wilfriede van Assche, Senior Vice President & General Counsel and Secretary
 
Ms. van Assche joined Ceres in 2000. She has more than 20 years of legal experience in the plant biotechnology and seed industry. Until 2000, Ms. van Assche was the General Counsel of the plant biotechnology and seed divisions of Aventis, a leading life sciences company that is now part of Bayer AG. Previously, she was the General Counsel at Plant Genetic Systems N.V. since 1988. Ms. van Assche holds a law degree from the University of Leuven and a postgraduate degree from the College of Europe. She is a member of the State Bar of California.
 
J.  Jefferson Gwyn, Ph.D., Vice President of Breeding and Genomics
 
Dr. Gwyn joined Ceres in 2008. He oversees crop improvement in switchgrass, sorghum and other energy crops. He also manages our field research center near College Station, Texas. Prior to joining Ceres, Dr. Gwyn was head of soybean trait development at Syngenta Seeds, Inc. Earlier in his career, Dr. Gwyn established and managed cotton breeding and trait programs stations in the United States and Brazil for Bayer Cotton Seed International. He was also a project director and program manager in corn trait breeding for DeKalb Genetics. Dr. Gwyn began his career as a cotton breeder and plant geneticist with Chembred, Inc. (American Cyanamid). He holds a Ph.D. in genetics from


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Texas A&M University and a Master’s Degree in genetics and plant breeding from Iowa State University. He completed his undergraduate studies at the University of Arkansas.
 
Michael Stephenson, Vice President of Operations
 
Mr. Stephenson joined Ceres in 2008. Prior to joining Ceres, Mr. Stephenson was a general manager for one of the brands of AgReliant Genetics, the fifth largest corn seed company in the United States, from 2000 to 2008. In addition to his commercial experience, Mr. Stephenson has chaired the American Seed Trade Association’s corn and sorghum division, and served as President of the Soybean Research Foundation and Regional Vice President of American Seed Trade Association. Mr. Stephenson holds a B.S. in Business Administration from the University of Kansas.
 
Roger Pennell, Ph.D., Vice President of Trait Development
 
Dr. Pennell joined Ceres in 1998 and held various research management positions until 2009 when he assumed his current role as Vice President of Trait Development. Dr. Pennell is an Adjunct Professor in the Department of Molecular, Cellular and Developmental Biology at the University of California, Los Angeles and a frequent reviewer for the scientific press. Dr. Pennell holds a Ph.D. from University College London. He performed post-doctoral research at the John Innes Institute and Wageningen Agricultural University, and in 1990 was the recipient of a prestigious Royal Society University Research Fellowship, which he used at University College London and, from 1995, at the Salk Institute. During this time, Dr. Pennell studied cellular and molecular aspects of plant growth, development and disease resistance, and has published more than 40 scientific papers on these subjects.
 
Board of Directors
 
Our board of directors currently consists of eleven members. Our amended and restated certificate of incorporation and bylaws, which will become effective immediately prior to the completion of this offering, will permit our board of directors to establish by resolution the authorized number of directors.
 
Our amended and restated certificate of incorporation and our amended and restated bylaws will provide for a classified board of directors consisting of three classes, with staggered three-year terms as follows:
 
  •  Class I directors, whose initial term will expire at the annual meeting of stockholders to be held in 2012;
 
  •  Class II directors, whose initial term will expire at the annual meeting of stockholders to be held in 2013; and
 
  •  Class III directors, whose initial term will expire at the annual meeting of stockholders to be held in 2014.
 
At each annual meeting of stockholders after the initial classification, upon expiration of the term of a class of directors, directors in that class will be elected for three-year terms at the annual meeting of stockholders held in the year in which that term expires. Each director’s term continues until the election and qualification of his or her successor, or his or her earlier death, resignation or removal. Any increase or decrease in the number of directors will be distributed among three classes so that, as nearly as possible, each class will consist of one-third of the total number of directors.
 
Upon the completion of this offering, the Class I directors will consist of          ,          , and          ; the Class II directors will consist of          ,          ,          and           ; and the Class III directors will consist of          ,          ,          and          .
 
The classification of our board of directors and provisions described above may have the effect of delaying or preventing changes in our control or management. See “Description of Capital Stock —


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Anti-Takeover Provisions to be in Effect Upon the Completion of this Offering — Amended and Restated Certificate of Incorporation and Bylaw Provisions”.
 
Risk Oversight
 
The board of directors is responsible for general oversight of company risk and risk management, and reviews management’s strategies for adequately mitigating and managing the identified risks. Although our board of directors administers this risk management oversight function, our Audit Committee supports our board of directors in discharging its oversight duties and address risks. Our board of directors expects company management to consider risk and risk management in its business decisions, to develop and monitor risk management strategies and processes for day-to-day activities and to implement risk management strategies adopted by the committees and the board of directors.
 
Director Independence
 
Upon the completion of this offering, we expect that our common stock will be listed on the Nasdaq Global Market. Under the rules of the Nasdaq Global Market, independent directors must comprise a majority of a listed company’s board of directors within a specified period of the completion of this offering. In addition, the rules of the Nasdaq Global Market require that, subject to specified exceptions, each member of a listed company’s audit, compensation and nominating and governance committees be independent. Audit committee members must also satisfy the independence criteria set forth in Rule 10A-3 under the Exchange Act. Under the rules of the Nasdaq Global Market, a director will only qualify as an “independent director” if, in the opinion of that company’s board of directors, that person does not have a relationship that would interfere with the exercise of independent judgment in carrying out the responsibilities of a director.
 
In order to be considered to be independent for purposes of Rule 10A-3, a member of an audit committee of a listed company may not, other than in his or her capacity as a member of the audit committee, the board of directors, or any other board committee: (1) accept, directly or indirectly, any consulting, advisory, or other compensatory fee from the listed company or any of its subsidiaries; or (2) be an affiliated person of the listed company or any of its subsidiaries.
 
In           2011, our board of directors undertook a review of its composition, the composition of its committees and the independence of each director. Based upon information requested from and provided by each director concerning his or her background, employment and affiliations, including family relationships, our board of directors has determined that none of Messrs. De Logi, Brandys, Debbane, Goldberg, Kiley, Krieger, Olivier, Van Acker and Ms. Devenyns, representing nine of our eleven directors, has a relationship that would interfere with the exercise of independent judgment in carrying out the responsibilities of a director and that each of these directors is “independent” as that term is defined under the rules of the Nasdaq Global Market.
 
Our board of directors also determined that Messrs.           ,           and          , who comprise our Audit Committee, and Messrs.           ,          ,           and          , who comprise our Compensation Committee, satisfy the independence standards for those committees established by applicable SEC rules and the rules of The Nasdaq Stock Market. In making this determination, our board of directors considered the relationships that each non-employee director has with our company and all other facts and circumstances our board of directors deemed relevant in determining their independence, including the beneficial ownership of our capital stock held by each non-employee director.
 
Committees of the Board of Directors
 
Our board of directors has established an Audit Committee and a Compensation Committee and intends to establish a Nominating and Governance Committee prior to the completion of this offering.


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Each committee will have the composition and responsibilities described below as of the completion of this offering.
 
Audit Committee
 
Our Audit Committee is currently comprised of Mr. Kiley, Mr. Olivier and Mr. De Logi, who is the chair of the Audit Committee. The composition of our Audit Committee will meet the requirements for independence under the current Nasdaq Global Market and SEC rules and regulations within the specified time periods. Each member of our Audit Committee possesses financial sophistication as defined under the rules of the Nasdaq Global Market. Mr.            is our “Audit Committee financial expert” as that term is defined in Item 407(d)(5)(ii) of Regulation S-K promulgated under the Securities Act. Being an “Audit Committee financial expert” does not impose on Mr.            any duties, obligations or liabilities that are greater than are generally imposed on him as a member of our Audit Committee and our board of directors. Our board of directors will adopt a new charter for our Audit Committee, which provides, among other things, that our Audit Committee will:
 
  •  oversee our accounting and financial reporting processes and audits of our financial statements;
 
  •  be directly responsible for the appointment, retention, compensation and oversight of the work of the independent registered public accounting firm;
 
  •  have the sole authority to preapprove any non-audit services to be provided by the independent registered public accounting firm and to review with the lead audit partner whether any of the audit team members receive any discretionary compensation from the audit firm with respect to non-audit services performed by the independent registered public accounting firm;
 
  •  actively engage in dialogue with the independent registered public accounting firm with respect to any disclosed relationships or services that may impact the objectivity and independence of the independent registered public accounting firm and recommending that the board of directors take, appropriate action to oversee the independence of the independent auditor; and
 
  •  discuss the adequacy of the Company’s internal control over financial reporting with the independent registered public accounting firm and management and review and discuss any changes implemented by management to address control deficiencies or to make controls more effective.
 
Compensation Committee
 
Our Compensation Committee is comprised of Messrs. Brandys, De Logi, Goldberg and Olivier, who is the chair of the Compensation Committee. The composition of our Compensation Committee will meet the requirements for independence under the current Nasdaq Global Market and SEC rules and regulations within the specified periods. The purpose of our Compensation Committee is to set compensation policy, administer compensation plans and recommend compensation for executive officers to the board of directors. Our board of directors will adopt a new charter for our Compensation Committee prior to this offering. Under this new charter, our Compensation Committee will discharge the responsibilities of our board of directors relating to compensation of our executive officers, and will, among other things:
 
  •  establish and review our overall compensation philosophy and executive compensation levels and make recommendations to the board of directors;
 
  •  review and approve, or recommend that our board of directors approve, the compensation of our executive officers other than the chief executive officer;
 
  •  review and approve the compensation of the chief executive officer;
 
  •  review and recommend to our board of directors the compensation of our directors;


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  •  review and approve, or recommend that our board of directors approve, the terms of any material agreements with our executive officers and new or prospective hires;
 
  •  establish and administer bonus and other performance-based compensation programs;
 
  •  administer our equity incentive plans and review and approve, or recommend that our board of directors approve, awards thereunder;
 
  •  review and approve, or recommend that our board of directors approve, perquisites, equity incentive awards and cash payments made to executive officers;
 
  •  assist in developing and evaluating the senior leadership team and assist in developing succession and continuity plans;
 
  •  review our compensation and benefit plans to determine whether they create risks that are reasonably likely to have a material adverse effect on the company; and
 
  •  review, discuss with management, and approve the compensation, discussion and analysis for our public filings.
 
Nominating and Governance Committee
 
We intend to establish a Nominating and Governance Committee prior to the completion of this offering. Our Nominating and Governance Committee will be comprised of          ,          ,          and          . The composition of our Nominating and Governance Committee will meet the requirements for independence under the current Nasdaq Global Market and SEC rules and regulations within the specified periods. Our Nominating and Governance Committee will, among other things:
 
  •  identify and recommend director nominees;
 
  •  recommend directors to serve on our various committees; and
 
  •  implement our corporate governance guidelines.
 
We intend to post the charters of our Audit, Compensation and Nominating and Governance Committees, and any amendments that may be adopted from time to time, on our website.
 
Compensation Committee Interlocks and Insider Participation
 
During fiscal 2010, our Compensation Committee was comprised of Messrs. Brandys, De Logi, Goldberg and Olivier. None of them has at any time during the last fiscal year been one of our officers or employees, and none has had any relationships with our company of the type that is required to be disclosed under Item 404 of Regulation S-K. None of our executive officers served as a member of the board of directors, or as a member of the compensation or similar committee, of an entity that has one or more executive officers who served on our board of directors or Compensation Committee during fiscal 2010. Mr. Olivier has pecuniary interests in his affiliated fund and may be deemed to have an interest in certain transactions with us, as more fully described in “Certain Relationships and Related Party Transactions” below.
 
Code of Business Ethics and Conduct
 
Our board of directors has adopted a code of business ethics and conduct. The code of business ethics and conduct applies to all of our employees, officers and directors, including those officers responsible for financial reporting. The full text of our code of business ethics and conduct is posted on our website at www.ceres.net. We intend to disclose future amendments to our code of business ethics and conduct, or waivers of these provisions, on our website and also in our periodic filings with the SEC.


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Limitation of Liability and Indemnification of Officers and Directors
 
Our amended and restated certificate of incorporation and bylaws, which will become effective upon the completion of this offering, limit the liability of our directors, officers, employees and other agents to the fullest extent permitted by Delaware law. Section 145 of the Delaware General Corporation Law permits indemnification of officers, directors and other agents under certain circumstances and subject to certain limitations. Delaware law also permits a corporation to not hold its directors personally liable for monetary damages for breach of their fiduciary duties as directors, except for liability for:
 
  •  breach of their duty of loyalty to us or our stockholders;
 
  •  acts or omissions not in good faith or that involve intentional misconduct or a knowing violation of law;
 
  •  unlawful payments of dividends or unlawful stock repurchases or redemptions as provided in Section 174 of the Delaware General Corporation Law; and
 
  •  any transaction from which the director derived an improper personal benefit.
 
These limitations of liability do not apply to liabilities arising under the federal or state securities laws and do not affect the availability of equitable remedies such as injunctive relief or rescission. Our amended and restated certificate of incorporation will also permit us to secure insurance on behalf of any officer, director, employee or other agent for any liability arising out of his or her actions in this capacity. We have obtained directors’ and officers’ liability insurance to cover certain liabilities described above. We plan to enter into separate indemnity agreements with each of our directors and executive officers that require us to indemnify such persons against any and all expenses (including attorneys’ fees), witness fees, judgments, fines, settlements and other amounts incurred (including expenses of a derivative action) in connection with any action, suit or proceeding or alternative dispute resolution mechanism, inquiry hearing or investigation, whether threatened, pending or completed, to which any such person may be made a party by reason of the fact that such person is or was a director, an officer or an employee of us or any of our affiliated enterprises, provided that such person must follow the procedures for determining entitlement to indemnification set out in the indemnity agreements. The indemnity agreements will also set forth other procedures that will apply in the event of a claim for indemnification thereunder. We believe that these provisions and agreements are necessary to attract and retain qualified persons as executive officers and directors of our company.
 
At present, there is no pending litigation or proceeding involving any of our directors or executive officers as to which indemnification is required or permitted, and we are not aware of any threatened litigation or proceeding that may result in a claim for indemnification.
 
The limitation of liability and indemnification provisions in our amended and restated certificate of incorporation and bylaws may discourage stockholders from bringing a lawsuit against directors for breach of their fiduciary duties. They may also reduce the likelihood of derivative litigation against directors and officers, even though an action, if successful, might provide a benefit to us and our stockholders. Our results of operations and financial conditions may be negatively affected to the extent we pay the costs of settlement and damage awards against directors and officers pursuant to these indemnification provisions.
 
Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, executive officers or persons controlling us, we have been informed that, in the opinion of the SEC, such indemnification is against public policy as expressed in the Securities Act and is therefore unenforceable.
 
Director Compensation
 
Director Compensation Prior to this Offering
 
Prior to this offering, we have not paid our directors any cash compensation or directors’ fees for their service on the board of directors. We have, however, provided annual stock option grants to


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Messrs. Brandys and Kiley, pursuant to their director services arrangements. These option grants generally vest over four years, with 25 percent vesting after the first year and the remainder vesting ratably each month thereafter over the next three years. We also have a consulting agreement with Dr. Goldberg pursuant to which we reimburse him for reasonable out of pocket expenses incurred in the performance of his consulting duties of up to $40,000 per year. In addition, pursuant to the consulting agreement, Dr. Goldberg received four stock option grants, each covering 15,000 shares of common stock, up to an aggregate of 60,000 stock options. The following table shows, for the year ended August 31, 2010, certain information with respect to the compensation of our non-employee directors:
 
                 
    Option
   
    Awards
   
Name
 
($)(1)(2)
 
Total ($)
 
Pascal Brandys
    23,270       23,270  
Thomas Kiley
    46,540       46,540  
 
(1) The amounts in the “Option Awards” column reflect the aggregate grant date fair value of stock options granted during fiscal 2010, computed in accordance with ASC Topic 718, including a grant of options to purchase 15,000 shares to Mr. Brandys and options to purchase 30,000 shares to Mr. Kiley, each with an exercise price of $2.25 per share. The assumptions used by us in determining the grant date fair value of option awards are set forth in Note 6 to our consolidated financial statements included elsewhere in this prospectus. These amounts do not correspond to the actual value that may be recognized by the directors.
 
(2) As of August 31, 2010, members of our board of directors held outstanding stock option awards as follows: Mr. De Logi held 250,000 outstanding stock option awards, Mr. Brandys held 75,000 outstanding stock option awards, Mr. Debbane held 20,000 outstanding stock option awards, Dr. Goldberg held 80,000 outstanding stock option awards, Mr. Kiley held 170,000 outstanding stock option awards, and Mr. Olivier held 20,000 outstanding stock option awards.
 
Our employee directors, Richard Hamilton and Richard Flavell, do not receive any compensation for their service as directors. The compensation that we pay to Dr. Hamilton is discussed in the “Executive Compensation” section of this prospectus. Dr. Flavell is employed in the capacity of Chief Scientific Officer and receives cash compensation and equity awards in such capacity, as determined by our Compensation Committee.


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COMPENSATION DISCUSSION AND ANALYSIS
 
Executive Compensation
 
The following discussion describes and analyzes the compensation of our “named executive officers” for fiscal 2010, who are Richard Hamilton, our President and Chief Executive Officer, or CEO, Paul Kuc, our Chief Financial Officer, or CFO, and J. Jefferson Gwyn, our Vice President of Breeding and Genomics, Roger Pennell, our Vice President of Trait Development and Michael Stephenson, our Vice President of Operations, our three most highly compensated executive officers during fiscal 2010, other than the CEO and CFO.
 
We were formed in 1996 and became operational in 1997. While our founders continue to serve us in key roles, we have added a number of executive officers since our formation, including our CEO, CFO and other executives. These additional executives have joined us at various times since 1996. We are building a fully integrated seed company capable of serving the commercial-scale needs of the emerging renewable energy industry. Our success depends, among other things, on attracting and retaining executive officers with experience and skills in a number of different areas as we continue to develop new products and seek to commercialize them.
 
Executive Compensation Procedures
 
Annually, we review the compensation of our management and employees, including our named executive officers. We follow a formal review process, which consists primarily of individual evaluations and scoring of employee performance, based on meeting personal, departmental and overall company goals. Potential compensation changes are based on the rank and distribution of these scores within the individual employee’s level, department and the overall company, as well as budgetary goals.
 
Our Compensation Committee has historically reviewed and recommended, and our board of directors has approved, the compensation of our CEO, CFO and other named executive officers. Our Compensation Committee has taken into consideration the input and recommendations of our CEO regarding the performance and compensation of named executive officers other than himself. Upon completion of this offering, we expect that our Compensation Committee will continue to review and approve (or recommend to the board of directors for approval) the compensation of all of our named executive officers and oversee and administer our executive compensation programs and initiatives, and will also be responsible for the evaluation of the performance of our named executive officers. The Compensation Committee will continue to take into consideration input and recommendations from our CEO with respect to the performance and compensation of executive officers other than himself; however, the Compensation Committee will retain the authority to make the final recommendation to the board for approval. Furthermore, the Compensation Committee will meet outside the presence of the CEO when determining his compensation.
 
Our approach to structuring and determining compensation for our named executive officers is related to our stage of development. Prior to this offering, we have been a privately held company. In determining executive compensation, we informally considered a wide variety of factors in arriving at our compensation decisions, including the competitive market for corresponding positions within comparable geographic areas, and compensation arrangements at companies of similar size and stages of development in the biotechnology and renewable energy industries. Information about these corresponding positions was based on the general and personal knowledge of our Compensation Committee members and board of directors and their experiences with other companies, as well as consultations with our CEO and human resources staff and their prior experience and personal knowledge from contacts with other professionals in the industry. In addition, our Compensation Committee and board of directors consulted publicly available compensation surveys to understand our compensation practices as compared to those of other companies with similar employee numbers, revenues, market capitalization, and other measures within our industry. The primary survey that we reviewed in 2010 was the Radford Global Life Sciences Survey (Southern California), which


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aggregated survey results from 130 biotechnology, pharmaceutical and medical device companies with revenues of less than $1 billion. We targeted our compensation structure for our executive management team to meet a 60th percentile benchmark, although individual compensation levels may vary from this target based on the other factors discussed herein.
 
In addition to the foregoing factors, our Compensation Committee also considered the experience levels and past performance of our named executive officers in determining their compensation levels.
 
Compensation Philosophy and Objectives
 
We favor a “pay-for-performance” compensation philosophy that is driven by individual and corporate performance, while balancing short-term and long-term company goals. We use a combination of cash payments and equity awards that we believe to be appropriate for motivating our executive officers. In addition, we believe that internal pay equity is an important consideration in determining executive compensation. However, we do not use a formulaic approach to determine pay components or amounts. As we gain experience as a public company, we expect that the specific direction, emphasis and components of our executive compensation program will continue to evolve. Our executive compensation program is currently designed to:
 
  •  align the interests of our executive officers with stockholders by motivating executive officers to meet our long-term objectives and increase stockholder value by rewarding executive officers when stockholder value increases;
 
  •  attract and retain talented and experienced executives who will strategically address our short-term and long-term needs;
 
  •  reward executives whose knowledge, skills and performance are critical to our success;
 
  •  ensure fairness among the executive management team by recognizing the contributions each executive makes to our success; and
 
  •  foster a shared commitment among executives by aligning their individual goals with the goals of the executive management team and our stockholders.
 
Our executive compensation program rewards corporate achievement, as well as team and individual accomplishments, by emphasizing a combination of corporate results and individual accountability. To help achieve these objectives, the Compensation Committee has tied a portion of the executives’ overall compensation to key business, financial and operational goals, such as revenue, product development, manufacturing metrics, business development and innovation.
 
We also seek to promote a long-term commitment to us by our executives. We believe that there is great value to us in having a team of long-tenured, seasoned managers. Our team-focused culture and management processes are designed to foster this commitment. In addition, our equity compensation program and the vesting schedule attached to equity awards is based upon the requirement of continued employment for four years for the executive to fully vest in the equity award, and is intended to retain our executives and reinforce this long-term commitment.
 
Elements of Compensation and Pay Mix
 
For fiscal 2010, our executive compensation consisted of the following elements (discussed in detail below) to promote our pay-for-performance philosophy and other compensation goals and objectives:
 
  •  base salary;
 
  •  annual cash bonuses linked to our overall performance and individual performance;
 
  •  grants of long-term equity-based compensation;


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  •  health and retirement benefits generally available to employees;
 
  •  limited severance payments for certain of our executives; and
 
  •  limited personal benefits for certain of our executives.
 
We combine these elements to form compensation packages that provide competitive pay, reward the achievement of financial, operational and strategic objectives, align the interests of our executive officers and other senior personnel with those of our stockholders, and balance short-term and long-term incentives.
 
We believe this combination of elements provides a well-proportioned mix of secure compensation, and at-risk compensation. By following this approach, we motivate our executives to focus on business results that will produce a high level of short-term and long-term performance for us and potential long-term value creation for our executives, as well as reducing the risk of recruitment of top executive talent by competitors.
 
Short-Term Incentives
 
Base Salary.  Base salary is designed to provide our executive officers with steady cash flow during the course of the year that is not contingent on short-term variations in our corporate performance. The base salaries established for fiscal 2010 for each of our named executive officers were intended to reflect wages that we believe are competitive for positions in companies of similar size and stage of development. The setting of salaries also includes a subjective judgment as to appropriate levels taking into account each individual’s job duties, responsibilities and experience and comparisons to the salaries of our other named executive officers. Base salaries are reviewed at least annually (or more frequently in specific circumstances) and may be recommended for adjustment from time to time based on the results of this review. Following our initial public offering, we expect that salary increases will continue to be determined using a combination of relevant competitive market data and assessment of individual performance. In fiscal 2010, we did not increase the base salaries of our named executive officers. In 2011, based on the Compensation Committee’s review of the Company’s performance as well as the individual named executive officer’s contributions to that performance in fiscal 2010, we increased the base salaries of our named executive officers as follows: Dr. Hamilton’s base salary was increased by 2.7%, Mr. Kuc’s base salary was increased by 5%, Dr. Gwyn’s base salary was increased by 15%, Dr. Pennell’s base salary was increased by 8.7%, and Mr. Stephenson’s base salary was increased by 2.8%. The higher increases for Dr. Gwyn and Dr. Pennell were implemented in order to bring their base salaries in line with our targeted benchmark of our peer companies as described above.
 
Cash Bonuses.  Historically, we have awarded cash bonuses to our named executive officers shortly after the end of each calendar year. Target bonus amounts are individually negotiated at the time each named executive is hired and actual amounts are awarded each year based on performance during the prior fiscal year. The Compensation Committee evaluates company and individual performance throughout the year and, after the end of the fiscal year, determines bonuses based on such performance and recommends bonus payout levels to the board of directors for approval.
 
For fiscal 2010, our bonus payout was not based on a specific formula but was determined based upon the Compensation Committee’s review of the following factors: (1) our success in achieving our corporate objectives for the plan year, (2) the individual’s contributions to the successful completion of such corporate objectives, and (3) the individual’s success in achieving his or her personal goals and objectives for the plan year. Our corporate objectives were a combination of business, operating, financial and technology based goals that were evaluated throughout the year by the board of directors. For fiscal 2010, some of the key corporate objectives used by the Compensation Committee to determine bonus payouts were as follows:
 
  •  achievement of targeted technical goals in agronomy, breeding, trait and product development;


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  •  expansion of collaborations with potential customers and end-users of our products;
 
  •  achievement of successful fermentation and field trial results with sweet sorghum; and
 
  •  achievement of key finance, audit and budgetary goals.
 
At the end of fiscal 2010, the Compensation Committee (in consultation with the CEO other than with respect to himself) assessed our accomplishments in achieving our corporate goals described above and our overall performance and subjectively determined the percentage payout for each of the named executive officers. The following table sets forth the 2010 bonuses paid as a percentage of base salary for each of the named executive officers:
 
                 
    Target Bonus as a
  Actual Bonus as
    Percent of Base
  Percent of Base
Name
 
Salary (%)
 
Salary (%)
 
Richard Hamilton
    35       17.5  
Paul Kuc
    30       25  
J. Jefferson Gwyn
    30       25  
Roger Pennell
    30       20  
Michael Stephenson
    30       20  
 
The Compensation Committee determined that bonus payouts to named executive officers would be less than the target amounts for fiscal 2010 based on several subjective and objective factors, including the following: the Company’s desire to enhance internal pay equity for the fiscal year among other non-executive officers, budgetary constraints, Company performance, general economic factors, and an analysis of actions taken at other companies in our industry.
 
The Compensation Committee then recommended these payout levels to the board of directors, and the board of directors approved the payments.
 
Long-Term Incentives
 
Long-Term Equity Compensation.  Our equity incentive program is intended to reward longer-term performance and to help align the interests of our executive officers with those of our stockholders. We believe that long-term performance is achieved through an ownership culture that rewards such performance by our executive officers through the use of equity incentives. Prior to this offering, our long-term incentives to date have consisted of stock option grants. Our stock option grants generally have a four-year vesting schedule with 25 percent vesting after the first year and the remainder vesting ratably each month thereafter over the next three years. We believe that our equity incentive program is an important retention tool for our employees, including our named executive officers.
 
Initial equity compensation awards for our named executive officers are individually negotiated with each executive officer at the time they are hired. In fiscal 2010, we granted additional stock option awards in connection with our named executive officers’ annual performance reviews and promotions. Equity awards to executive officers have not historically been based upon a formula, but rather are determined on a case-by-case basis considering the factors described above in our compensation philosophy and objectives. As a recruitment incentive, we have also granted restricted stock awards with time and performance-based vesting to Dr. Gwyn. The performance-based criteria applicable to the restricted stock grant are tied to Mr. Gwyn’s annual performance ratings on his achievement of certain leadership, development and research goals related to our breeding programs.
 
In connection with our transition to a publicly-traded company, we expect to continue to grant stock options to our executive officers, and we may also utilize other types of equity awards. We also intend to adopt a new 2011 Equity Compensation Plan to become effective immediately prior to the completion of this offering.


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Other Compensation and Benefits
 
Other Employee Benefits.  We maintain a 401(k) plan in which substantially all of our employees are entitled to participate, under which we provide matching contributions of 50 percent of the employee’s contributions up to a maximum of 4 percent of the employee’s income (or 50 percent of employee contributions of up to 8 percent of the employee’s base salary). We provide health care, dental, vision, life insurance, disability and other welfare benefits to all full-time employees, including our executive officers. These benefits are available to substantially all employees, subject to applicable laws. We generally do not provide other personal benefits to our named executive officers that are not available to other full-time employees on the same terms, though we occasionally provide reimbursement of moving expenses and associated tax gross ups for those amounts as a recruitment tool. We have also provided our CFO with reimbursement of legal expenses relating to his immigration and naturalization. In addition, in accordance with our company policy, Dr. Gwyn and a number of other non-executive employees who work as breeders and agronomists are provided with a company vehicle in order to drive to different field locations. These employees, including Dr. Gwyn, may also occasionally use the company vehicles for personal reasons. The only incremental cost to us for personal use of these vehicles is the cost of gasoline when the employee is driving the vehicle for personal reasons. We have estimated this cost for Dr. Gwyn below in the “Summary Compensation Table”.
 
Severance and Change of Control Benefits.  Other than with respect to our CEO and CFO, our named executive officers are not generally entitled to contractual severance or change in control benefits, and any severance provided to a named executive officer would be negotiated at the time of his or her departure. Our arrangements with our CEO and CFO were individually negotiated in connection with their hire. Our CEO is entitled to limited salary continuation in the event his employment is terminated by us without cause. In addition, our CFO is entitled to a severance payment in the event his employment is terminated in connection with an acquisition of the Company. Under our 2010 Stock Option/Stock Issuance Plan, or the 2010 Plan, vesting of equity awards will accelerate under certain circumstances as described in detail below in the section captioned “Executive Compensation — Potential Severance Payments upon Termination and upon Termination Following a Change in Control”. We believe that these limited benefits provide us with the most flexibility to make a change in executive management, if such a change is in our stockholders’ best interests, while providing a certain amount of certainty and security to our top executives so they can focus on their duties. For more detail on our severance and change in control arrangements, please see “Potential Severance Payments upon Termination and upon Termination Following a Change in Control” and “Executive Employment Agreements”.
 
Tax Considerations.  Section 162(m) of the Internal Revenue Code disallows a tax deduction for any publicly held corporation for individual compensation exceeding $1.0 million in any taxable year for our named executive officers (other than our chief financial officer), unless compensation is performance-based. As we are not currently publicly-traded, our board of directors has not previously taken the deductibility limit imposed by Section 162(m) into consideration in setting compensation. We expect that our Compensation Committee may in the future, where reasonably practicable, take steps to ensure that the variable compensation paid to our executive officers is deductible by the Company. However, our Compensation Committee may, in its judgment, authorize compensation payments that do not meet the deductibility requirements imposed by Section 162(m) when it believes that such payments are appropriate to attract and retain executive talent.


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Summary Compensation Table
 
The following table sets forth information regarding compensation earned by our named executive officers during fiscal 2010.
 
                                                 
                    All Other
   
                Option
  Compensation
   
Name and Principal Position
 
Year
 
Salary ($)
 
Bonus ($)(1)
 
Awards ($)(2)
 
($)
 
Total ($)
 
Richard Hamilton
                                               
President and Chief Executive Officer
    2010       380,000       66,500             7,616(3)       454,116  
Paul Kuc
                                               
Chief Financial Officer
    2010       260,000       65,000       155,133       65,021(4)       545,154  
J. Jefferson Gwyn
                                               
Vice President of Breeding and Genomics
    2010       200,577       50,000       315,558       29,129(5)       595,264  
Roger Pennell
                                               
Vice President of Trait Development
    2010       231,154       46,000       214,421       8,278(6)       499,853  
Michael Stephenson
                                               
Vice President of Operations
    2010       250,000       50,000       155,133       6,744(7)       461,877  
 
(1) The amounts reported in this column represent discretionary bonuses determined by the board of directors in respect of performance in fiscal 2010. These bonuses were paid in early 2011.
 
(2) The amounts in the “Option Awards” column reflect the aggregate grant date fair value of stock options granted, computed in accordance with ASC Topic 718. The assumptions used by us in determining the grant date fair value of option awards are set forth in Note 6 to our Consolidated Financial Statements included elsewhere in this prospectus. See the “Grants of Plan-Based Awards” table for more information on stock option grants made in fiscal 2010. These amounts do not correspond to the actual value that may be recognized by the named executive officers.
 
(3) This amount includes a company matching contribution to our 401(k) plan in the amount of $7,350 and company-paid life insurance premiums in the amount of $266.
 
(4) This amount includes a company matching contribution to our 401(k) plan in the amount of $5,600, company-paid life insurance premiums in the amount of $266, an amount of $6,750 to cover legal expenses associated with Mr. Kuc’s naturalization, reimbursement of a $28,650 realtor’s fee associated with the sale of Mr. Kuc’s primary residence pursuant to the terms of his offer letter, and an amount of $23,755 to cover the taxes associated with the reimbursement.
 
(5) This amount includes a company matching contribution to our 401(k) plan in the amount of $8,023, company-paid life insurance premiums in the amount of $266, and $13,373 in a closing cost reimbursements associated with the purchase of Dr. Gwyn’s primary residence according to his offer letter, a gross up amount of $5,481 gross-up to pay taxes associated with the reimbursement, and $503 for miscellaneous moving expense reimbursement, and the estimated portion his company vehicle’s gasoline expense incurred by us that is attributable to his personal use of the vehicle in the amount of $1,483.
 
(6) This amount includes a company matching contribution to our 401(k) plan in the amount of $8,012 and company-paid life insurance premiums in the amount of $266.
 
(7) This amount includes a company matching contribution to our 401(k) plan in the amount of $6,494 and company-paid life insurance premiums in the amount of $250.
 
Grants of Plan-Based Awards
 
The following table sets forth information regarding grants of compensation in the form of plan-based awards made during fiscal 2010 to our named executive officers.
 
                                 
        All Other Option
       
        Awards: Number of
  Exercise or Base
  Grant Date Fair
        Securities Underlying
  Price of Option
  Value of Option
Name
 
Grant Date
 
Options (#)(1)
 
Awards ($/Sh)(2)
 
Awards ($)(3)
 
Paul Kuc
    6/8/2010       100,000       2.25       155,133  
J. Jefferson Gwyn
    9/15/2009 (4)     115,000       2.25       160,425  
      6/8/2010       100,000       2.25       155,133  
Roger Pennell
    9/15/2009 (4)     42,500       2.25       59,288  
      6/8/2010       100,000       2.25       155,133  
Michael Stephenson
    6/8/2010       100,000       2.25       155,133  


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(1) Stock option awards vest as to 25% of the original number of shares on the first anniversary of the vesting commencement date, which is a date fixed by our board of directors when granting options, and the remainder of the shares vest ratably each month thereafter until the fourth anniversary of the vesting commencement date. Notwithstanding the foregoing, awards may be subject to acceleration of vesting upon a change in control of our company and termination of employment following a change in control, as further described below in “Executive Compensation — Potential Severance Payments upon Termination and upon Termination Following a Change in Control”. All options were granted under either our 2000 Stock Option/Stock Issuance Plan, as amended, or our 2010 Stock Option/Stock Issuance Plan, which are described below under “Compensation Discussion and Analysis — Executive Compensation — Equity Compensation Plans”.
 
(2) Represents the fair market value of a share of our common stock, as determined by our board of directors, on the respective option grant date. For a discussion of our methodology for determining the fair value of our common stock, see the “Management’s Discussion and Analysis of Financial Condition and Results of Operations — Critical Accounting Policies and Estimates” section of this prospectus.
 
(3) Reflects the grant date fair value of each stock option granted computed in accordance with ASC Topic 718. The assumptions used by us in determining the grant date fair value of option awards are set forth in Note 6 to our Consolidated Financial Statements included elsewhere in this prospectus. These amounts do not correspond to the actual value that may be recognized by the named executive officers.
 
(4) The grants to Dr. Gwyn and Dr. Pennell on September 15, 2009 were made outside the annual grant process in connection with their internal promotions.
 
Outstanding Equity Awards at Fiscal 2010 Year-End
 
The following table itemizes outstanding options and restricted stock awards held by the named executive officers as of August 31, 2010.
 
                                                                 
        Option Awards   Stock Awards
        Securities
  Securities
  Total
               
        Underlying
  Underlying
  Number of
              Market
        Unexercised
  Unexercised
  Securities
          Number of
  Value of
        Options
  Options
  Underlying
  Option
  Option
  Shares That
  Shares That
    Option
  Exercisable
  Unexercisable
  Unexercised
  Exercise
  Expiration
  Have Not
  Have Not
   
Grant Date
 
(#)(1)*
 
(#)(1)
 
Options (#)
 
Price ($)(2)
 
Date
 
Vested (#)(3)
 
Vested ($)(4)
 
Richard Hamilton
    12/19/2002       1,200,000               1,200,000 (5)     0.65       12/18/2012                  
      1/16/2006       205,000               205,000 (6)     1.30       1/15/2016                  
      12/21/2007       562,000               562,000 (7)     2.25       12/20/2017                  
Paul Kuc
    9/3/2008       330,000               330,000 (8)     2.25       9/2/2018                  
      6/8/2010       100,000               100,000 (9)     2.25       6/7/2020                  
J. Jefferson Gwyn
    8/19/2008       75,000               75,000 (10)     2.25       8/18/2018                  
      9/15/2009       115,000               115,000 (11)     2.25       9/14/2019                  
      6/8/2010       100,000               100,000 (9)     2.25       6/7/2020       5,000       12,200  
Roger Pennell
    5/17/2006       80,000               80,000 (12)     1.30       5/16/2016                  
      9/15/2009       42,500               42,500 (11)     2.25       9/14/2019                  
      6/8/2010       100,000               100,000 (9)     2.25       6/7/2020                  
Michael Stephenson
    6/4/2008       300,000               300,000 (13)     2.25       6/3/2018                  
      6/8/2010       100,000               100,000 (9)     2.25       6/7/2020                  
 
Stock options may be exercised prior to vesting, subject to repurchase rights that expire over the vesting periods indicated in the footnotes below. Accordingly, all stock options outstanding as of August 31, 2010 were exercisable in full.
 
(1) All options vest as to 25% of the original number of shares on the first anniversary of the vesting commencement date, which is a date fixed by our board of directors when granting options, and the remainder of the shares vest ratably each month thereafter until the fourth anniversary of the vesting commencement date. Notwithstanding, awards may be accelerated upon a change in control of our company, and/or termination of employment following a change in control, as further described below in “Executive Compensation — Potential Severance Payments upon Termination and upon Termination Following a Change in Control”. Unvested options are subject to early exercise, in which case, until they vest, the shares acquired pursuant to such exercise will be restricted and subject to repurchase by the Company at the exercise price upon the participant termination of employment.
 
(2) The option exercise price represents the fair market value of our common stock as of the date of grant, as determined by our board of directors.
 
(3) The remainder of the restricted stock award held by Dr. Gwyn vests in equal annual installments on the following dates: April 1, 2011 (which installment did vest), and April 1, 2012, subject to the achievement of certain performance milestones.


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(4) The aggregate dollar value of unvested restricted stock represents the product of the fair market value of our common stock on August 31, 2010, which was determined by our board of directors to be approximately $2.44 per share, and the number of shares that remained unvested on August 31, 2010.
 
(5) The vesting commencement date of this grant is September 23, 2002.
 
(6) The vesting commencement date of this grant is January 16, 2006.
 
(7) The vesting commencement date of this grant is December 21, 2007.
 
(8) The vesting commencement date of this grant is September 3, 2008.
 
(9) The vesting commencement date of this grant is June 8, 2010.
 
(10) The vesting commencement date of this grant is August 11, 2008.
 
(11) The vesting commencement date of this grant is August 1, 2009.
 
(12) The vesting commencement date of this grant is April 1, 2006.
 
(13) The vesting commencement date of this grant is June 1, 2008.
 
Option Exercises and Stock Vested in Fiscal 2010
 
The following table contains information about stock awards that vested for each of our named executive officers during fiscal 2010, including the number of shares acquired upon the vesting of stock awards and the value realized, before payment of any applicable withholding taxes. There were no stock options exercised by our named executive officers during fiscal 2010.
 
                 
    Stock Awards
    Number of Shares
   
    Acquired on
  Value Realized on
Name
 
Vesting
 
Vesting (1)
 
J. Jefferson Gwyn
    2,500     $ 5,800  
 
(1) The aggregate dollar value realized upon vesting of restricted stock represents the product of the fair market value of our common stock on the vesting date, which was determined by our board of directors to be approximately $2.32 per share, and the number of shares that vested on such date. For a discussion of our methodology for determining the fair value of our common stock, see the “Management’s Discussion and Analysis of Financial Condition and Results of Operations — Critical Accounting Policies and Estimates” section of this prospectus.
 
Pension Benefits and Non-Qualified Deferred Compensation
 
None of our named executive officers participates in, or has an account balance in, a qualified or non-qualified pension plan or deferred compensation plan sponsored by us.
 
Potential Severance Payments upon Termination and upon Termination Following a Change in Control
 
Our CEO is entitled to certain severance payments in the event of his termination of employment without cause, and our CFO is entitled to certain severance payments in the event he is terminated in connection with an acquisition of the Company.
 
The following table summarizes the potential payments and benefits payable to each of our named executive officers upon (i) termination of employment without cause in the absence of a change in control and (ii) termination of employment without cause or “involuntary termination” (as


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defined in the 2010 Plan and described below) following a change in control, assuming, in each situation, that termination and change of control, as applicable, occurred on August 31, 2010.
 
                                 
        Involuntary Termination in
    Termination Without Cause
  Connection with or within
    in the Absence of a
  12 Months Following a
    Change in Control   Change in Control
        Value of
      Value of
        Accelerated
      Accelerated
    Base Salary
  Options or
  Base Salary
  Options or
Name
 
($)(1)
 
Shares ($)
 
($)(1)
 
Shares ($)(2)
 
Richard Hamilton
    285,000               285,000       35,593  
Paul Kuc
                    260,000       51,656  
J. Jefferson Gwyn
                            54,713  
Roger Pennell
                            25,056  
Michael Stephenson
                            45,125  
 
(1) The amounts in this column represent the salary continuation of our CEO in the event of his termination of employment by us without cause, and a lump sum payment to our CFO in the event of his termination in connection with an acquisition of the Company.
 
(2) This column assumes that options and restricted stock accelerate in the event of an “involuntary termination” (as defined in the 2010 Plan and described below) within 12 months after a change in control or similar corporate transaction. The amounts represent, in (1) respect of each unvested stock option outstanding as of August 31, 2010, the number of shares underlying such stock option, multiplied by the excess of the fair market value of our common stock on such date, as determined by our board of directors to be $2.44 per share, over the exercise price of such option, and (2) in respect of any outstanding restricted stock, the number of shares of restricted stock outstanding as of August 31, 2010, multiplied by the fair market value of our common stock on such date, as determined by our board of directors to be $2.44 per share.
 
Executive Employment Agreements
 
We do not have formal employment agreements with any of our named executive officers. The initial compensation and terms of employment of each named executive officer was set forth in an offer letter that we executed with him or her at the time his or her employment with us commenced. Each offer letter provides for an initial base salary, bonus opportunity, equity grant and other benefits to be provided to the executive officer. Other than the CEO and CFO, none of our named executive officers is entitled to any contractual severance benefits upon termination of employment, and each individual is employed “at will”. Under our CEO’s offer letter, both we and the CEO are required to provide 90 days’ notice to the other party if we or he intend to terminate his employment for any reason. In addition, our CEO is entitled to severance in the form of continued base salary payments for a period of nine months in the event his employment is terminated without cause by us. Our CFO is entitled to severance in the amount of 12 months’ salary in the event that his employment is terminated in connection with an acquisition of the Company. Mr. Stephenson’s offer letter provides that if we decide to terminate his employment or if he resigns, 6 months’ notice must be given to the other party.
 
Equity Compensation Plans
 
Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
 
General.  Our board of directors adopted, and our stockholders approved, the 2010 Plan on June 7, 2010. The 2010 Plan provides for the grant of incentive stock options, nonstatutory stock options, and shares of restricted or unrestricted common stock. Upon the signing of the underwriting


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agreement for this offering, no further awards will be granted under the 2010 Plan. However, all outstanding awards will continue to be governed by their existing terms.
 
Share Reserve.  The maximum number of shares of common stock issuable under the 2010 Plan is 1,757,400, increased by the number of shares underlying awards granted under the 2010 Plan and predecessor plans that were expired or were otherwise forfeited; provided that no more than 8,029,345 shares may be issued under the plan. As of May 1, 2011, 782,599 shares of common stock remained available for future issuance.
 
Administration.  The 2010 Plan is administered by our board of directors, but administrative functions may be delegated to the Compensation Committee.
 
Eligibility.  Employees, non-employee members of the board of directors and consultants and other independent service providers are eligible to participate in the 2010 Plan. The plan administrator determines which eligible individuals will receive grants and the terms of their awards. Incentive stock options, however, may be granted only to employees.
 
Stock Options.  With respect to stock options granted under the 2010 Plan, the exercise price may not be less than 100% of the fair market value of our common stock on the date of grant (or for incentive stock options, 110% of fair market value if the grantee is a ten percent stockholder). In general, the maximum term of stock options granted under the 2010 Plan may not exceed ten years from the date of grant (or in the case of incentive stock options granted to any 10% stockholder, the term may not exceed five years from the date of grant). Unless otherwise provided by a participant’s stock option agreement, if a participant’s service relationship with us ceases for any reason other than disability or death, the participant may exercise the vested portion of any options for three months following the cessation of service. If a participant’s service relationship with us terminates by reason of disability or death, the participant or a personal representative may generally exercise the vested portion of any options for 12 months after the date of such termination. In no event, however, may an option be exercised beyond the expiration of its original term. The plan administrator may allow a participant to exercise unvested stock options, upon which such participant will receive restricted shares that will vest in accordance with the stock option’s existing vesting schedule. These restricted shares are subject to repurchase by us if the participant terminates service with us.
 
Stock Issuance.  Restricted or unrestricted stock may be issued for a purchase price of not less than 85% of fair market value of our common stock (or 110% of fair market value if the grantee is a ten percent stockholder). The purchase price consideration may be provided in the form of cash or check, or provision of past services to the Company. If the participant terminates employment for any reason, any unvested shares will be forfeited, and any cash consideration paid will be repaid to the participant. The plan administrator may waive these forfeiture provisions. To the extent shares issued are restricted, they may vest in accordance with terms determined by the administrator, including performance or time-based vesting. Shares of common stock acquired under such awards may, but need not, be subject to a share repurchase option in our favor in accordance with a vesting schedule to be determined by our board of directors. If a participant’s service relationship with us terminates, we may repurchase or otherwise reacquire any or all of the shares of common stock subject to the award that have not vested as of the date of termination.
 
Repurchase Rights.  The Company has a right of first refusal over any stock issued under the 2010 Plan until the common stock is first registered. The Company also has the right to repurchase any unvested shares at the exercise or purchase price of such shares upon a participant’s termination of employment.
 
Corporate Transactions.  In the event of an acquisition of the Company, a merger, or other significant “corporate transaction”, (as defined in the 2010 Plan) all outstanding stock options and restricted shares will vest in full, unless the successor company assumes or replaces such stock options or restricted shares. In addition, all repurchase rights of the Company will terminate unless those rights are assigned to the successor company. Alternatively, in the case of stock options, the


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plan administrator may provide, either at grant or thereafter, that upon the occurrence of a corporate transaction, (1) all or a portion of outstanding stock options will automatically accelerate and repurchase rights will terminate, or (2) all or a portion of outstanding stock options will automatically accelerate and repurchase rights will terminate if the participant suffers an “involuntary termination” (as defined in the 2010 Plan and described below) within up to 12 months after the corporate transaction. With respect to stock issued under the plan, in the event of a significant corporate transaction, all repurchase rights will terminate and all restricted shares will vest in full, unless the successor corporation is assigned the repurchase rights. The plan administrator may alternatively provide either at grant or thereafter that upon a corporate transaction, the repurchase rights relating to outstanding shares will terminate and vesting will accelerate if the participant suffers an “involuntary termination” within up to 18 months after the corporate transaction. Under our current outstanding stock option agreements and restricted stock agreement, if a participant’s employment is terminated due to an involuntary termination within 12 months following a corporate transaction all outstanding awards will automatically vest. Under the 2010 Plan and the outstanding award agreements, “corporate transaction” means any person becoming the beneficial owner of 20% or more of our outstanding securities, a change in the majority of the members of our board of directors, our consummation of a merger or consolidation, our shareholders’ approval of a plan of complete liquidation or dissolution of Ceres or our sale of all or substantially all of our assets. “Involuntary termination” means a participant’s involuntary dismissal by us other than for “misconduct”, or his or her voluntary resignation following a change in position that results in a material reduction in responsibility level, a reduction in compensation by more than 15 percent or a relocation of more than 50 miles. “Misconduct” means the commission of an act of fraud, embezzlement or dishonesty, an unauthorized use of confidential information or trade secrets or any other intentional misconduct that materially adversely affects our business or affairs.
 
Ceres, Inc. 2000 Stock Option/Stock Issuance Plan
 
We have also granted equity awards (and awards remain outstanding) under the Company’s 2000 Stock Option/Stock Issuance Plan, as amended, the terms of which are substantially the same as the 2010 Plan. No further awards will be granted under the 2000 Stock Option/Stock Issuance Plan.
 
Ceres, Inc. 2011 Equity Incentive Plan
 
The following is a summary of the Ceres, Inc. 2011 Equity Incentive Plan, or the 2011 Plan, which was adopted by our board of directors on          , and approved by the Company’s shareholders on          . This summary is not intended to be a complete description of all provisions of the Plan and is qualified in its entirety by reference to the 2011 Plan, which will be filed as an exhibit to this registration statement.
 
General.  The 2011 Plan provides for grants of equity and equity-based awards to certain members of our board of directors, employees and consultants.
 
Share Reserve.  The maximum number of shares of common stock issuable under the 2011 Plan is , which will be increased by any shares tendered or withheld to pay the exercise price of an award or to satisfy any Company withholding obligations, as well as the number of shares underlying awards granted under the 2011 Plan, the 2010 Plan and predecessor plans that have expired or were otherwise forfeited.
 
Administration.  The 2011 Plan will be administered by the Compensation Committee. The Compensation Committee may delegate certain of its authority to one or more officers of the Company.
 
Eligibility.  Employees, members of our board of directors and certain consultants will be eligible to participate in the 2011 Plan. The plan administrator determines which eligible individuals will receive grants, and the terms of their awards. Incentive stock options, however, may be granted only to employees.


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Performance-Based Awards.  The Compensation Committee may grant performance-based awards that will be based upon the Company’s achievement of objective performance criteria as selected by the Compensation Committee within 90 days following the beginning of the applicable performance period. The performance criteria will be one or more of the following measures: .
 
Stock Options.  The plan administrator may grant incentive stock options (intended to qualify under Section 422 of the Internal Revenue Code) or nonqualified stock options under the 2011 Plan. The exercise price of any stock option granted may not be less than 100% of the fair market value of the Company’s common stock on the date of grant (or, for incentive stock options, 110% of fair market value if the grantee is a ten percent stockholder). The term of any stock option granted may not exceed ten years (or, for incentive stock options, five years for any grantee who is a ten percent stockholder). The plan administrator will determine the vesting conditions and schedule for each stock option granted, which may be based upon the participant’s service with the Company, the achievement of performance criteria, or any other criteria.
 
Restricted Stock.  The plan administrator may grant restricted stock under the 2011 Plan. The plan administrator will determine the restrictions and vesting conditions and schedule for each grant of restricted stock, which may be based upon the participant’s service with the Company, the achievement of performance criteria, or any other criteria.
 
Stock Appreciation Rights.  The plan administrator may grant stock appreciation rights. The exercise price of any stock appreciation right granted may not be less than 100% of the fair market value of the Company’s common stock on the date of grant. The plan administrator will determine the vesting conditions and schedule for each stock appreciation right, which may be based upon the participant’s service with the Company, the achievement of performance criteria, or any other criteria.
 
Performance Awards, Dividend Equivalents, Stock Payments, Restricted Stock Units and Other Awards.  The plan administrator may also grant performance awards that are linked to the performance criteria set forth in the 2011 Plan or other criteria. Performance awards may be paid in common stock, cash or a combination thereof, as determined by the plan administrator. The plan administrator may also make grants of dividend equivalents, stock payments, deferred stock, restricted stock units (settled in cash, common stock or a combination thereof) and other equity or equity based awards. The term, exercise or purchase price, vesting conditions and other terms and conditions of any such awards will be determined by the plan administrator.
 
Corporate Events.  In the event of a transaction between the Company and its stockholders that affects the number or kind of shares of common stock or the share price of common stock and causes a change in the per-share value of the common stock underlying outstanding awards, the number and type of securities underlying outstanding awards will be equitably adjusted and the plan administrator will make equitable adjustments to the aggregate number and kind of shares that may be issued under the 2011 Plan. In the event of any other stock dividend, stock split, combination or exchange of shares, merger, consolidation or other distribution (other than normal cash dividends) of Company assets to stockholders, or any other change affecting the shares of the Company’s stock or the share price of the Company’s stock, the plan administrator may make equitable adjustments to the aggregate number and kind of shares issuable under the 2011 Plan, the number and kind of shares underlying outstanding awards and the terms and conditions of outstanding awards. In such event, the plan administrator may also take any one or more of the following actions: terminate the award for cash, replace the award for other rights or property, provide for the assumption or substitution of the award by a successor corporation, make adjustments to awards, accelerate the vesting or exercisability of the award, or provide that the award cannot vest or be exercised after the event.
 
Amendment and Termination.  The 2011 Plan may be amended, suspended or terminated by the board of directors; however, any material amendments are subject to shareholder approval.
 
Certain Federal Income Tax Consequences.  The following is a brief summary of certain significant United States Federal income tax consequences under the Internal Revenue Code, as in


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effect on the date of this summary, applicable to the Company and plan participants in connection with awards under the 2011 Plan. This summary assumes that all awards will be exempt from, or comply with, the rules under Section 409A of the Internal Revenue Code regarding nonqualified deferred compensation. If an award constitutes nonqualified deferred compensation and fails to comply with Section 409A, the award will be subject to immediate taxation and tax penalties in the year the award vests. This summary is not intended to be exhaustive, and, among other things, does not describe state, local or non-United States tax consequences, or the effect of gift, estate or inheritance taxes. References to “the Company” in this summary of tax consequences mean Ceres, Inc., or any affiliate of Ceres, Inc. that employs or receives the services of a recipient of an award under the 2011 Plan, as the case may be.
 
The grant of stock options under the 2011 Plan will not result in taxable income to the recipient of the options or an income tax deduction for the Company. However, the transfer of our common stock to an option holder upon exercise of his or her option may or may not give rise to taxable income to the option holder and a tax deduction for the Company depending upon whether such option is a nonqualified stock option or an incentive stock option.
 
The exercise of a nonqualified stock option by an option holder generally results in immediate recognition of taxable ordinary income by the option holder and a corresponding tax deduction for the Company in the amount by which the fair market value of the shares of our common stock purchased, on the date of such exercise, exceeds the aggregate exercise price paid. Any appreciation or depreciation in the fair market value of those shares after the exercise date will generally result in a capital gain or loss to the holder at the time he or she disposes of those shares.
 
The exercise of an incentive stock option by the option holder is exempt from income tax, although not from the alternative minimum tax, and does not result in a tax deduction for the Company if the holder has been an employee of the Company at all times beginning with the option grant date and ending three months before the date the holder exercises the option (or twelve months in the case of termination of employment due to disability). If the option holder has not been so employed during that time, the holder will be taxed as described above for nonqualified stock options. If the option holder disposes of the shares purchased more than two years after the option was granted and more than one year after the option was exercised, then the option holder will recognize any gain or loss upon disposition of those shares as capital gain or loss. However, if the option holder disposes of the shares prior to satisfying these holding periods (known as a “disqualifying disposition”), the option holder will be obligated to report, as taxable ordinary income for the year in which that disposition occurs, the excess, with certain adjustments, of the fair market value of the shares disposed of, on the date the incentive stock option was exercised, over the exercise price paid for those shares. The Company would be entitled to a tax deduction equal to that amount of ordinary income reported by the option holder. Any additional gain realized by the option holder on the disqualifying disposition would be capital gain. If the total amount realized in a disqualifying disposition is less than the exercise price of the incentive stock option, the difference would be a capital loss for the holder.
 
The grant of stock appreciation rights does not result in taxable income to the recipient of a stock appreciation right or a tax deduction for the Company. Upon exercise of a stock appreciation right, the amount of any cash the participant receives (before applicable tax withholdings) and the fair market value as of the exercise date of any common stock received are taxable to the participant as ordinary income and deductible by the Company.
 
A participant will not recognize any taxable income upon the award of shares of restricted stock which are not transferable and are subject to a substantial risk of forfeiture. Dividends paid with respect to restricted stock prior to the lapse of restrictions applicable to that stock will be taxable as compensation income to the participant. Generally, the participant will recognize taxable ordinary income at the first time those shares become transferable or are no longer subject to a substantial risk of forfeiture, in an amount equal to the fair market value of those shares when the restrictions lapse. However, a participant may elect to recognize taxable ordinary income upon the award date of


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restricted stock based on the fair market value of the shares of common stock subject to the award on the award date. If a participant makes that election, any dividends paid with respect to that restricted stock will not be treated as compensation income, but rather as dividend income, and the participant will not recognize additional taxable income when the restrictions applicable to his or her restricted stock award lapse. Assuming compliance with the applicable tax withholding and reporting requirements, the Company will be entitled to a tax deduction equal to the amount of ordinary income recognized by a participant in connection with his or her restricted stock award in the Company’s taxable year in which that participant recognizes that ordinary income.
 
The grant of restricted stock units does not result in taxable income to the recipient of a restricted stock unit or a tax deduction for the Company. The amount of cash paid (before applicable tax withholdings) or the then-current fair market value of the common stock received upon settlement of the restricted stock units is taxable to the recipient as ordinary income and deductible by the Company.
 
The grant of a cash-based award, other stock-based award or dividend equivalent right generally should not result in the recognition of taxable income by the recipient or a tax deduction by the Company. The payment or settlement of a cash-based award, other stock-based award or dividend equivalent right should generally result in immediate recognition of taxable ordinary income by the recipient equal to the amount of any cash paid (before applicable tax withholding) or the then-current fair market value of the shares of common stock received, and a corresponding tax deduction by the Company. If the shares covered by the award are not transferable and subject to a substantial risk of forfeiture, the tax consequences to the participant and the Company will be similar to the tax consequences of restricted stock awards, described above. If an other stock-based award consists of unrestricted shares of common stock, the recipient of those shares will immediately recognize as taxable ordinary income the fair market value of those shares on the date of the award, and the Company will be entitled to a corresponding tax deduction.
 
Under section 162(m) of the Internal Revenue Code, the Company may be limited as to federal income tax deductions to the extent that total annual compensation in excess of $1 million is paid to our CEO or any one of our three highest paid executive officers, other than the CEO or CFO, who are employed by us on the last day of our taxable year. However, certain “performance-based compensation” the material terms of which are disclosed to and approved by our stockholders is not subject to this deduction limitation. The 2011 Plan has been structured with the intention that compensation resulting from stock options and stock appreciation rights granted under the 2011 Plan will be qualified performance-based compensation and, assuming the plan is approved by the stockholders, deductible without regard to the limitations otherwise imposed by section 162(m) of the Internal Revenue Code. The 2011 Plan allows the Compensation Committee discretion to award restricted stock, restricted stock units, cash-based awards and other stock-based awards in the form of performance compensation awards that are intended to be qualified performance-based compensation, as described under “Performance-Based Awards” above.
 
New Plan Benefits
 
As of          , there were approximately           directors, approximately          employees and          approximately           consultants who would be eligible to receive awards under the 2011 Plan. Because it will be within the plan administrator’s discretion to determine which directors, employees and consultants will receive awards under the 2011 Plan and the types and amounts of those awards, it is not possible at present to specify the benefits that would be received under the 2011 Plan by directors, employees and consultants.


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EQUITY COMPENSATION PLAN INFORMATION
 
The following table provides information as of August 31, 2010 regarding compensation plans under which our equity securities are authorized for issuance:
 
                         
                Number of
 
                Securities
 
                Remaining
 
    Number of
    Weighted
    Available
 
    Securities
    Average
    for Future
 
    to be Issued
    Exercise
    Issuance
 
    Upon Exercise of
    Price of
    Under Equity
 
    Outstanding
    Outstanding
    Compensation
 
Plan Category
 
Options
   
Options
   
Plans
 
 
Equity compensation plans approved by stockholders
    6,874,588 (1)   $ 1.48       1,148,257 (2)
Equity compensation plans not approved by stockholders
                 
                         
Total
    6,874,588     $ 1.48       1,148,257  
                         
 
(1) Consists of shares underlying stock options granted under the 2010 Plan and the 2000 Plan.
 
(2) Consists of shares issuable under the 2010 Plan. No additional shares are available for future issuance under the 2000 Plan other than in respect of shares underlying outstanding stock options. The shares issuable under the 2010 Plan may be increased by the number of shares that would have been issuable under any stock option granted under the 2010 Plan or the 2000 Plan that were forfeited or that expired without being exercised. Upon the completion of this offering and the approval of the 2011 Plan, no future grants will be made under the 2010 Plan.


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CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS
 
In addition to the compensation arrangements, including employment, termination of employment and change-in-control and indemnification arrangements, discussed above under “Management”, “Compensation Discussion and Analysis” and the registration rights described below under “Description of Capital Stock — Registration Rights”, the following is a description of each transaction since January 1, 2007, and each currently proposed transaction in which:
 
  •  we have been or are to be a participant;
 
  •  the amount involved exceeds or will exceed $120,000; and
 
  •  any of our directors, executive officers or holders of more than 5% of any class of our capital stock at the time of the transactions in issue, or any immediate family member of or person sharing the household with any of these individuals, had or will have a direct or indirect material interest.
 
Preferred Stock Financings
 
Series F Convertible Preferred Stock Financing
 
In September 2007, we sold an aggregate of 11,538,462 shares of Series F convertible preferred stock in a private placement at a per share purchase price of $6.50 pursuant to a stock purchase agreement. Purchasers of the Series F convertible preferred stock also received, for each share purchased, a warrant to purchase 0.20 shares of our common stock at an exercise price of $6.50 per share. Purchasers of the Series F convertible preferred stock included holders of more than 5% of our outstanding capital stock and affiliates of certain of our directors. The following table summarizes purchases of Series F convertible preferred stock:
 
                         
            Shares of Common
    Number of
  Aggregate
  Stock Underlying
Name
 
Shares
 
Purchase Price
 
Warrants
 
Artal Luxembourg S.A. 
    568,518     $ 3,695,367.00       113,704  
Gimv N.V. 
    196,154     $ 1,275,001.00       39,231  
Adviesbeheer Gimv Life Sciences N.V. 
    34,616     $ 225,004.00       6,924  
H&Q Healthcare Investors
    40,846     $ 265,499.00       8,170  
H&Q Life Sciences Investors
    28,385     $ 184,502.50       5,677  
KBC Private Equity N.V. 
    77,000     $ 500,500.00       15,400  
KBC Private Equity Fund Biotech N.V. 
    37,500     $ 243,750.00       7,500  
Oppenheimer International Growth Fund
    1,900,000     $ 12,350,000.00       380,000  
Quantum Industrial Partners LDC
    287,923     $ 1,871,499.50       57,585  
SFM Domestic Investments LLC
    31,991     $ 207,941.50       6,399  
Rothschild Trust Guernsey Limited as Trustee F/B/O the Ambergate Trust
    308,000     $ 2,002,000.00       61,600  
Warburg Pincus Private Equity IX, L.P. 
    6,923,078     $ 45,000,007.00       1,384,616  
Galleon Admiral’s Offshore, Ltd. 
    552,225     $ 3,589,462.50       110,446  
Galleon Technology Partners II, LP
    87,360     $ 567,840.00       17,472  
Galleon Technology Offshore, Ltd. 
    464,866     $ 3,021,629.00       92,973  
 
Series G Convertible Preferred Stock Financing
 
In June 2010, we sold an aggregate of 3,076,923 shares of Series G convertible preferred stock in a private placement at a per share purchase price of $6.50 pursuant to a stock purchase agreement. Purchasers of the Series G convertible preferred stock also received, for each share purchased, a warrant to purchase one share of our common stock at an exercise price of $6.50 per share. Purchasers of the Series G convertible preferred stock included holders of more than 5% of our


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outstanding capital stock and affiliates of certain of our directors. The following table summarizes purchases of Series G convertible preferred stock:
 
                         
            Shares of Common
    Number of
  Aggregate
  Stock Underlying
Name
 
Shares
 
Purchase Price
 
Warrants
 
Artal Luxembourg S.A. 
    1,361,538     $ 8,849,997.00       1,361,538  
Rothschild Trust Guernsey Limited as Trustee F/B/O the Ambergate Trust
    1,300,000     $ 8,450,000.00       1,300,000  
Gimv N.V. 
    340,000     $ 2,210,000.00       340,000  
Adviesbeheer Gimv Life Sciences 2004 N.V. 
    60,000     $ 390,000.00       60,000  
The Kiley Revocable Trust
    15,385     $ 100,002.50       15,385  
 
Indemnification Arrangements
 
We have entered, or will enter, into an indemnity agreement with each of our directors and officers. The indemnity agreements and our amended and restated certificate of incorporation and amended and restated bylaws will require us to indemnify our directors and officers to the fullest extent permitted by Delaware law. Please see “Management — Limitation of Liability and Indemnification of Officers and Directors”.
 
Executive Compensation and Employment Arrangements
 
Please see “Compensation Discussion and Analysis — Executive Compensation” for information on compensation arrangements with our executive officers, including option grants and agreements with executive officers.
 
Investors’ Rights Agreement
 
We have entered into an investors’ rights agreement with certain holders of our common stock and preferred stock that provides for certain rights relating to the registration of their shares of common stock, including those issued upon conversion of their preferred stock. See “Description of Capital Stock — Registration Rights” below for additional information.
 
Offer Letters
 
We have entered into offer letters and other agreements containing compensation, termination and change of control provisions, among others, with certain of our executive officers as described under the caption “Compensation Discussion and Analysis — Executive Compensation — Executive Employment Agreements” above.
 
Related Person Transaction Policy
 
As provided in our current Audit Committee charter, our Audit Committee is responsible for reviewing and approving all related party transactions on an ongoing basis and must review any potential conflict of interest situations where appropriate.
 
Director Independence
 
For a discussion of the independence of our directors, please see “Management — Director Independence” above.


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PRINCIPAL STOCKHOLDERS
 
The following table sets forth information with respect to the beneficial ownership of our common stock, as of February 28, 2011, by:
 
  •  each person, or group of affiliated persons, who is known by us to beneficially own more than 5% of our voting securities;
 
  •  each of our directors;
 
  •  each of our named executive officers; and
 
  •  all of our directors and executive officers as a group.
 
Beneficial ownership is determined in accordance with the rules of the SEC and generally includes any shares over which the individual or entity has sole or shared voting power or investment power. The information does not necessarily indicate beneficial ownership for any other purpose. Except as indicated in the footnotes to this table and pursuant to applicable community property laws, to our knowledge the persons named in the table below have sole voting and investment power with respect to all shares of common stock beneficially owned.
 
Percentage ownership of our common stock in the table prior to the offering is based on 51,990,236 shares of our common stock outstanding on February 28, 2011. This number and the numbers of beneficially owned shares reported in the table below assume the automatic conversion of all outstanding shares of our preferred stock into 46,059,819 shares of common stock in connection with the completion of this offering. Percentage ownership of our common stock after this offering also assumes our sale of the           shares in this offering.
 
The number of shares beneficially owned by each person or group as of February 28, 2011 includes shares of common stock that such person or group had the right to acquire on or within 60 days after February 28, 2011, upon the exercise of options and warrants. References to options and warrants in the footnotes of the table below include only options and warrants outstanding as of February 28, 2011 that were exercisable on or within 60 days after February 28, 2011. For the purposes of calculating each person’s or group’s percentage ownership, stock options and warrants exercisable within 60 days after February 28, 2011 are included for that person or group but not the stock options or warrants of any other person or group.


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Except as otherwise set forth below, the address of the beneficial owner is c/o Ceres, Inc., 1535 Rancho Conejo Blvd., Thousand Oaks, CA 91320.
 
                                 
    Shares Beneficially Owned
  Shares Beneficially Owned
    Prior to Offering   After Offering
Name and Address of Beneficial Owner
 
Number (#)
 
Percentage (%)
 
Number (#)
 
Percentage (%)
 
5% Stockholders
                               
Artal Luxembourg S.A.(1)
    9,665,288       18.08                  
Warburg Pincus Private Equity IX, L.P.(2)
    8,307,694       15.56                  
Ambergate Trust(3)
    7,467,824       14.00                  
Oxford Bioscience entities(4)
    5,535,609       10.65                  
Gimv entities(5)
    4,444,978       8.48                  
Oppenheimer Growth entities(6)
    4,430,867       8.46                  
Quantum Industrial Partners LDC(7)(9)
    3,002,320       5.77                  
SFM Domestic Investments LLC(8)(9)
    333,592       *                  
Monsanto Company(10)
    3,333,333       6.41                  
Directors and Named Executive Officers
                               
Walter De Logi(11)
    1,600,000       3.06                  
Pascal Brandys(12)
    250,707       *                  
Raymond Debbane(13)
    50,000       *                  
Ruth Devenyns
          *                  
Richard Flavell(14)
    725,000       1.38                  
Robert Goldberg(15)
    624,083       1.20                  
Richard Hamilton(16)
    2,237,000       4.15                  
Thomas Kiley(17)
    200,770       *                  
David B. Krieger(2)(18)
    8,307,694       15.56                  
Edmund Olivier(4)(19)
    5,555,609       10.68                  
Gerard Van Acker
          *                  
Paul M. Kuc(20)
    430,000       *                  
J. Jefferson Gwyn(21)
    300,000       *                  
Roger Pennell(22)
    300,000       *                  
Michael Stephenson(23)
    400,000       *                  
All directors and executive officers as a group (16 persons)
    21,223,363       36.58                  
 
Represents beneficial ownership of less than 1%.
 
(1) Includes 1,475,242 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by Artal Luxembourg S.A. The address for Artal Luxembourg S.A. is 105 Grand-Rue, L-1661, Luxembourg.
 
(2) Includes 1,384,616 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by Warburg Pincus Private Equity IX, L.P., a Delaware partnership, or WP IX. The sole general partner of WP IX is Warburg Pincus IX LLC, a New York limited liability company, or WP IX LLC. Warburg Pincus Partners, LLC, a New York limited liability company, or WP Partners, is the sole member of WP IX LLC. Warburg Pincus & Co., a New York general partnership, or WP, is the managing member of WP Partners. WP IX is managed by Warburg Pincus LLC, a New York limited liability company, or WP LLC. David B. Krieger, one of


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our directors, is a Managing Director of WP LLC and a General Partner of WP. The shares and shares underlying warrants acquired by WP IX are reflected as indirectly owned by Mr. Krieger because of his affiliation with the Warburg Pincus entities. Mr. Krieger disclaims beneficial ownership of the shares and shares underlying warrants held by WP IX, except to the extent of his pecuniary interests therein. Charles R. Kaye and Joseph P. Landy are Managing General Partners of Warburg Pincus and Managing Members and Co-Presidents of WP and may be deemed to control the Warburg Pincus entities. Messrs. Kaye and Landy disclaim beneficial ownership of all shares held by the Warburg Pincus entities. The address for WP IX, WP IX LLC, WP Partners, WP, WP LLC, and Messrs. Kaye, Krieger and Landy is 450 Lexington Avenue, New York, NY 10017.
 
(3) Represents 7,467,824 shares of common stock held by Rothschild Trust Guernsey Limited as Trustee F/B/O the Ambergate Trust. Includes 1,361,600 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by Rothschild Trust Guernsey Limited as Trustee F/B/O the Ambergate Trust. Mr. De Logi is the settlor of the Ambergate Trust and one of the beneficiaries. Mr. De Logi disclaims beneficial ownership of the shares held by the Ambergate Trust. The address for Rothschild Trust Guernsey Limited is PO Box 472, St. Peter’s House, Le Bordage, St. Peter Port GY1 6AX, Guernsey.
 
(4) Represents 2,380,010 shares of common stock held by Oxford Bioscience Partners II, L.P., 309,695 shares of common stock held by Oxford Bioscience Partners (GS-Adjunct) II, L.P., 663,333 shares of common stock held by Oxford Bioscience Management Partners II, 487,227 shares of common stock held by Oxford Bioscience Partners (Adjunct) II, L.P. and 1,695,344 shares of common stock held by Oxford Bioscience Partners (Bermuda) II, Limited Partnership. OBP Management II L.P. is the general partner of Oxford Bioscience Partners II L.P., Oxford Bioscience Partners (Adjunct) II L.P. and Oxford Bioscience Partners (GS-Adjunct) II L.P. Edmund Olivier, Alan Walton, Cornelius Ryan and Jonathan Fleming are the general partners of OBP Management II L.P. OBP Management (Bermuda) II Limited Partnership is the general partner of Oxford Bioscience Partners (Bermuda) II Limited Partnership. Edmund Olivier, Alan Walton, Cornelius Ryan and Jonathan Fleming are the general partners of Oxford Bioscience Partners (Bermuda) II Limited Partnership. Messrs. Olivier, Walton, Ryan and Fleming all disclaim beneficial ownership of the shares except to the extent of their pecuniary interests therein. The shares acquired by the Oxford Bioscience entities are reflected as indirectly owned by Mr. Olivier because of his affiliation with the Oxford Bioscience entities. The address for Oxford Bioscience Partners is 222 Berkeley St. Suite 1960, Boston, MA 02116.
 
(5) Represents 254,007 shares of common stock held by Adviesbeheer Gimv Life Sciences 2004 N.V. and 4,190,971 shares of common stock held by Gimv N.V. Includes 66,924 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by Adviesbeheer Gimv Life Sciences 2004 N.V. and 379,231 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by Gimv N.V. The address for Adviesbeheer Gimv Life Sciences 2004 N.V. and Gimv N.V. is Karel Oomsstraat 37, B-2018, Antwerpen, Belgium.
 
(6) Represents 3,024,347 shares of common stock held by Oppenheimer International Growth Fund and 1,026,520 shares of common stock held by Oppenheimer MassMutual International Equity Fund. Includes 380,000 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by Oppenheimer International Growth Fund. The address for Oppenheimer International Growth Fund is 2 World Financial Center, 225 Liberty Street, New York, NY 10281.
 
(7) Represents 2,944,735 shares of common stock held by Quantum Industrial Partners LDC, an exempted limited duration company formed under the laws of the Cayman Islands, or QIP, and 57,585 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by QIP. The principal address of QIP is Kaya Flamboyan 9, Willemstad, Curacao. QIH Management Investor, L.P., or QIHMI, an investment advisory firm organized as a


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Delaware limited partnership, is a minority stockholder of, and is vested with investment discretion with respect to portfolio assets held for the account of QIP. The sole general partner of QIHMI is QIH Management LLC, a Delaware limited liability company, or QIH Management.
 
(8) Represents 327,193 shares of common stock held by SFM Domestic Investments LLC, a Delaware limited liability company, or SFMD, and 6,399 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by SFMD. The principal address of SFMD is at 888 Seventh Avenue, 33rd Floor, New York, New York 10106.
 
(9) Soros Fund Management LLC, or SFM LLC, a Delaware limited liability company, may be deemed the beneficial owner of the shares held for the account of SFMD and QIP. SFM is the manager of SFMD and the sole managing member of QIH Management. George Soros serves as Chairman of SFM LLC, Robert Soros serves as Deputy Chairman of SFM LLC, and Jonathan Soros serves as President and Deputy Chairman of SFM LLC.
 
(10) The address for Monsanto Company is 800 North Lindbergh Boulevard, St. Louis, Missouri 63167. Pursuant to the terms of the Investors’ Rights Agreement, Monsanto agreed that, subject to certain exceptions, it would not increase its ownership position to more than 15% of our then outstanding voting stock.
 
(11) Includes 160,000 shares of common stock held by Lynda De Logi, Walter De Logi’s spouse, and 250,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011.
 
(12) Includes 75,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 21,251 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Mr. Brandys’s cessation of service with us prior to vesting.
 
(13) Includes 20,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011.
 
(14) Includes 455,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 68,750 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Dr. Flavell’s cessation of service with us prior to vesting.
 
(15) Includes 544,083 shares of common stock held by The Robert Goldberg Revocable Living Trust and 80,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 9,376 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Dr. Goldberg’s cessation of service with us prior to vesting.
 
(16) Includes 100,000 shares of common stock held by Dr. Richard Hamilton 2011-Ceres GRAT and 1,967,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 93,667 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Dr. Hamilton’s cessation of service with us prior to vesting.
 
(17) Includes 170,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 31,563 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Mr. Kiley’s cessation of service with us prior to vesting. Includes 15,385 shares of common stock held by The Kiley Revocable Trust and 15,385 shares of common stock that may be acquired pursuant to the exercise of warrants held prior to this offering by The Kiley Revocable Trust.
 
(18) Consists of 8,307,694 shares of common stock held by WP IX, including the 1,384,616 shares identified in footnote 2.


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(19) Consists of 5,535,609 shares of common stock identified in footnote 4 and 20,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011.
 
(20) Consists of 430,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 216,875 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Mr. Kuc’s cessation of service with us prior to vesting.
 
(21) Includes 290,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 192,084 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Dr. Gwyn’s cessation of service with us prior to vesting.
 
(22) Includes 222,500 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 124,792 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Dr. Pennell’s cessation of service with us prior to vesting.
 
(23) Represents 400,000 shares of common stock issuable pursuant to stock options exercisable within 60 days of February 28, 2011, 187,500 of which are unvested and early exercisable and would be subject to a right of repurchase in our favor upon Mr. Stephenson’s cessation of service with us prior to vesting.


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DESCRIPTION OF CAPITAL STOCK
 
General
 
The following is a summary of our capital stock and certain provisions of our amended and restated certificate of incorporation and amended and restated bylaws, as they will be in effect upon the completion of this offering. This summary does not purport to be complete and is qualified in its entirety by the provisions of our amended and restated certificate of incorporation and amended and restated bylaws, copies of which will be filed with the SEC as exhibits to the registration statement of which this prospectus is a part.
 
Immediately following the completion of this offering, our authorized capital stock will consist of           shares, with a par value of $0.01 per share, of which:
 
  •            shares are designated as common stock; and
 
  •            shares are designated as preferred stock.
 
As of February 28, 2011, we had outstanding           shares of common stock, held of record by 170 stockholders, and no shares of preferred stock, assuming the automatic conversion of all outstanding shares of our convertible preferred stock into common stock immediately prior to the completion of this offering and the issuance of           shares of common stock upon the net exercise of Series F warrants and Series G warrants that expire upon the completion of this offering, based upon an initial public offering price of $      per share, the midpoint of the range set forth on the cover of this prospectus. In addition, as of February 28, 2011, we also had outstanding options to acquire 7,192,391 shares of common stock.
 
Common Stock
 
The holders of common stock are entitled to one vote per share on all matters submitted to a vote of our stockholders and do not have cumulative voting rights. Accordingly, holders of a majority of the shares of common stock entitled to vote in any election of directors may elect all of the directors standing for election. Subject to preferences that may be applicable to any preferred stock outstanding at the time, the holders of outstanding shares of common stock are entitled to receive ratably any dividends declared by our board of directors out of assets legally available. See the section entitled “Dividend Policy”. Upon our liquidation, dissolution or winding up, holders of our common stock are entitled to share ratably in all assets remaining after payment of liabilities and the liquidation preference of any then outstanding shares of preferred stock. Holders of common stock have no preemptive or conversion rights or other subscription rights. There are no redemption or sinking fund provisions applicable to the common stock.
 
Preferred Stock
 
After the completion of this offering, no shares of preferred stock will be outstanding. Pursuant to our amended and restated certificate of incorporation, our board of directors will have the authority, without further action by our stockholders, to issue from time to time up to          shares of preferred stock in one or more series. Our board of directors may designate the rights, preferences, privileges and restrictions of the preferred stock, including dividend rights, conversion rights, voting rights, terms of redemption, liquidation preference, sinking fund terms and the number of shares constituting any series or the designation of any series. The issuance of preferred stock or even the ability to issue preferred stock could have the effect of delaying, deterring or preventing a change in control.
 
Warrants
 
At February 28, 2011, we had warrants outstanding to purchase 6,046,157 shares of our common stock, assuming the automatic conversion of our preferred stock warrants into common stock. Except for The Samuel Roberts Noble Foundation, Inc. and Texas A&M University warrants of


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400,000 and 200,000, respectively, each warrant contains provisions for the adjustment of the exercise price and the number of shares issuable upon exercise upon the occurrence of certain events, including stock dividends, reorganizations, reclassifications and consolidations.
 
In June 2010, we sold an aggregate of 3,076,923 shares of Series G convertible preferred stock in a private placement pursuant to a stock purchase agreement. Purchasers of the Series G convertible preferred stock also received, for each share purchased, a warrant to purchase one share of our common stock at an exercise price of $6.50 per share. Upon the completion of this offering, all of these warrants will expire if not exercised.
 
In January 2010, we entered into a Loan and Security Agreement with Silicon Valley Bank, or SVB, to finance qualified equipment purchases, pursuant to which we granted SVB warrants to purchase 43,076 shares of our Series F convertible preferred stock at a price of $6.50 per share. The warrants expire on the later of February 29, 2020 or five years subsequent to the completion of our initial public offering.
 
In September 2007, we sold an aggregate of 11,538,462 shares of Series F convertible preferred stock in a private placement pursuant to a stock purchase agreement. Purchasers of the Series F convertible preferred stock also received, for each share purchased, a warrant to purchase 0.20 shares of our common stock at an exercise price of $6.50 per share. Upon the completion of this offering, all of these warrants will expire if not exercised.
 
In August 2007, we entered into an agreement with Texas A&M University, pursuant to which we granted Texas A&M University a warrant to purchase 200,000 shares of our common stock for an exercise price of $10.00 per share. The warrant vests in various installments based on certain research and commercialization milestones being met and will remain exercisable until August 28, 2017.
 
In May 2006, we entered into an agreement with The Samuel Roberts Noble Foundation, Inc., pursuant to which we granted the Noble Foundation a warrant to purchase 400,000 shares of our common stock for an exercise price of $10.00 per share. The warrant vests in equal installments of 100,000 shares on each of May 19, 2009, May 19, 2011, May 19, 2013, and May 19, 2015 and each installment will remain exercisable for a period of two years from the respective vesting date.
 
In July 2004, we entered into a borrowing agreement with SVB to finance construction of a greenhouse and tenant improvements at our Thousand Oaks, California facility, pursuant to which we granted SVB warrants to purchase 18,461 shares of our Series E preferred stock at a price of $6.50 per share, which were set to expire on the later of July 31, 2014 or five years after an initial public offering. During 2010, the warrants were extended and now expire on February 29, 2020 or five years subsequent to the completion of our initial public offering.
 
Registration Rights
 
Stockholder Registration Rights
 
In June 2010, we entered into an Amended and Restated Investors’ Rights Agreement, or the Investors’ Rights Agreement, with our major stockholders pursuant to which we agreed to provide certain rights to those stockholders that are a party to the Investors’ Rights Agreement to register the shares of our common stock (i) issuable upon conversion of outstanding convertible preferred stock, (ii) issued as a dividend or other distribution related to the convertible preferred stock, (iii) currently held or later acquired, and (iv) issuable upon the exercise of warrants held by any stockholder that is party to the agreement. We will bear all expenses incurred in connection with any underwritten registration, including, without limitation, all registration, filing and qualification fees, printers and accounting fees and the reasonable fees of counsel for the selling holders, but excluding underwriting discounts and commissions.


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The registration rights provided for under the Investors’ Rights Agreement terminate after the earlier of five years following the consummation of an initial public offering, or any such time as the holder would be able to dispose of all of its registrable securities in any three month period under SEC Rule 144.
 
Demand Registration Rights
 
Pursuant to the Investors’ Rights Agreement, if, at any time after six months after the effective date of the first registration statement for a public offering of our securities (other than a registration statement relating either to the sale of securities to our employees pursuant to a stock option, stock purchase or similar plan or an SEC Rule 145 transaction), upon the written request of the holders of at least 15% of the securities covered by the Investors’ Rights Agreement that we file a registration statement under the Securities Act covering the registration of at least 15% of the securities covered by the Investors’ Rights Agreement, then we are required to file a registration statement covering the resale of the common stock requested to be registered. We are not obligated to file a registration statement after we have effected five registration statements pursuant to the Investors’ Rights Agreement or during certain periods prior to and after a registration statement has been filed by the company or, for a period of 90 days in the event the board of directors, in its judgment, makes the determination that it would be seriously detrimental to the Company and its shareholders for such registration statement to be filed and is therefore essential to defer the filing of such registration statement.
 
If an underwriter selected for an underwritten offering advises the holders demanding registration that marketing factors require a limitation on the number of shares to be underwritten, then, subject to certain limitations, the number of shares of registrable securities that may be included in the underwriting will be allocated among all holders of registrable securities in proportion to the amount of our registrable securities owned by each holder.
 
Piggyback Registration Rights
 
Pursuant to the Investors’ Rights Agreement, if, subject to certain exceptions, we propose to register any of our stock or other securities under the Securities Act in connection with the public offering of such securities solely for cash, we are required to promptly give such holders written notice of such registration. Upon the written request of each eligible holder, we will, subject to certain limitations, cause to be registered under the Securities Act all such securities that each such holder has requested to be registered.
 
Stockholders with registration rights will sign agreements with the representatives of the underwriters prohibiting the exercise of their registration rights for 180 days, subject to extension under certain circumstances, following the date of this prospectus. These agreements are described below under “Underwriting”.
 
Anti-Takeover Provisions to be in Effect Upon the Completion of this Offering
 
Certain provisions of the Delaware General Corporation Law, or DGCL, and our amended and restated certificate of incorporation and bylaws that will become effective upon the completion of this offering may have the effect of delaying, deferring or discouraging another party from acquiring control of our company. These provisions, which are summarized below, may discourage certain types of coercive takeover practices and inadequate takeover bids and encourage anyone seeking to acquire control of our company to first negotiate with our board of directors. These provisions might also have the effect of preventing changes in our management and could make it more difficult to accomplish transactions that stockholders might otherwise deem to be in their best interests. However, we believe that the advantages gained by protecting our ability to negotiate with any unsolicited and potentially unfriendly acquirer outweigh the disadvantages of discouraging such proposals, because, among other reasons, the negotiation of such proposals could result in improving their terms.


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Amended and Restated Certificate of Incorporation and Bylaw Provisions
 
Upon the completion of this offering, our amended and restated certificate of incorporation and bylaws will include a number of provisions that may have the effect of delaying, deferring or discouraging another party from acquiring control of our company or preventing changes in our management, including the following:
 
  •  Issuance of Undesignated Preferred Stock.  Upon the completion of this offering and the filing of our amended and restated certificate of incorporation, our board of directors will have the authority, without further action by the stockholders, to issue up to           shares of undesignated preferred stock with rights, preferences and privileges designated from time to time by our board of directors without further action by stockholders. These rights, preferences and privileges could include dividend rights, conversion rights, voting rights, terms of redemption, liquidation preferences and sinking fund terms, any or all of which may be greater than the rights of common stock.
 
  •  Size of the Board of Directors and Filling Vacancies.  The number of directors constituting our board of directors may be set only by resolution adopted by a majority vote of our entire board of directors. Any vacancy on our board of directors, however occurring, including a vacancy resulting from an increase in the size of the board of directors, may only be filled by the affirmative vote of a majority of our directors then in office, even if less than a quorum.
 
  •  Classified Board.  Our board of directors will be divided into three classes of directors, with staggered three-year terms. Only one class of directors will be elected at each annual meeting of our stockholders, with the other classes continuing for the remainder of their respective three-year terms.
 
  •  No Cumulative Voting.  Our amended and restated certificate of incorporation and amended and restated bylaws do not permit cumulative voting in the election of directors. Cumulative voting allows a stockholder to vote a portion, or all of its shares for one or more candidates. The absence of cumulative voting makes it more difficult for a minority stockholder to gain a seat. Because our stockholders do not have cumulative voting rights, our stockholders holding a majority of the shares of our outstanding common stock will be able to elect all of our directors.
 
  •  Removal of Directors.  Directors can only be removed by our stockholders for cause and removal of a director will require a 662/3 stockholder vote.
 
  •  No Written Consent of Stockholders.  All stockholder actions are required to be taken by a vote of the stockholders at an annual or special meeting. Stockholders may not take action by written consent in lieu of a meeting. The inability of stockholders to take action by written consent means that a stockholder would need to wait until the next annual or special meeting to bring business before the stockholders for a vote.
 
  •  Special Meetings of Stockholders.  Special meetings of our stockholders may be called only by a majority of our board of directors, the chairman of our board of directors, our chief executive officer, or president (in the absence of a chief executive officer). Only those matters set forth in the notice of the special meeting may be considered or acted upon at a special meeting of our stockholders.
 
  •  Advance Notice Requirements for Stockholder Proposals and Director Nominations.  Our amended and restated bylaws provide advance notice procedures for stockholders seeking to bring business before our annual meeting of stockholders or to nominate candidates for election as directors at our annual meeting of stockholders. These procedures provide that notice must be timely given in writing prior to the meeting at which the action is to be taken and the form and content of such notice must comply with the applicable provisions of our amended and restated bylaws. These procedures may have the effect of precluding the conduct of certain business at a meeting if the proper procedures are not followed or may discourage or deter a potential acquirer


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  from conducting a solicitation of proxies to elect its own slate of directors or otherwise attempt to obtain control of us.
 
  •  Amendment to Amended and Restated Certificate of Incorporation and Bylaws.  Any amendment, repeal or modification of certain provisions of our amended and restated certificate of incorporation and bylaws will require a 662/3 stockholder vote. Provisions requiring such supermajority vote include, among other things, any amendment, repeal or modification of the provisions relating to the classification of our board of directors, the requirement that stockholder actions be effected at a duly called annual or special meeting of our stockholders and the designated parties entitled to call a special meeting of our stockholders.
 
Section 203 of the DGCL
 
Upon the completion of this offering, we will be subject to Section 203 of the DGCL. In general, Section 203 of the DGCL prohibits a publicly held Delaware corporation from engaging in a “business combination” with an “interested stockholder” for a three-year period following the time that this stockholder becomes an interested stockholder, unless it satisfies one of the following conditions:
 
  •  the transaction is approved by the board of directors prior to the time that the interested stockholder became an interested stockholder;
 
  •  upon consummation of the transaction which resulted in the stockholder becoming an interested stockholder, the interested stockholder owned at least 85% of the voting stock of the corporation outstanding at the time the transaction commenced; or
 
  •  at or subsequent to such time that the stockholder became an interested stockholder, the business combination was approved by the board of directors and authorized at an annual or special meeting of stockholders by at least two-thirds of the outstanding voting stock which is not owned by the interested stockholder.
 
In general, Section 203 defines “business combination” to include the following:
 
  •  any merger or consolidation involving the corporation and the interested stockholder;
 
  •  any sale, lease, exchange, mortgage, pledge, transfer or other disposition of the assets of the corporation with an aggregate market value of 10% or more of either the aggregate market value of all assets of the corporation on a consolidated basis or the aggregate market value of all of the outstanding stock of the corporation involving the interested stockholder;
 
  •  subject to certain exceptions, any transaction that results in the issuance or transfer by the corporation of any stock of the corporation to the interested stockholder;
 
  •  any transaction involving the corporation that has the effect of increasing the proportionate share of the stock or any class or series of the corporation beneficially owned by the interested stockholder; or
 
  •  the receipt by the interested stockholder of the benefit of any loans, advances, guarantees, pledges or other financial benefits by or through the corporation.
 
In general, Section 203 defines an “interested stockholder” as an entity or person who, together with the stockholder’s affiliates and associates (as defined in Section 203), beneficially owns, or within three years prior to the time of determination of interested stockholder status did own, 15% or more of the outstanding voting stock of the corporation.
 
Transfer Agent and Registrar
 
The transfer agent and registrar for our common stock will be          . The transfer agent’s telephone number is           .
 
Stock Exchange Listing
 
We intend to apply to have our common stock listed on the Nasdaq Global Market under the symbol “CERE”.


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SHARES ELIGIBLE FOR FUTURE SALE
 
Prior to this offering, there has been no public market for our common stock and we cannot assure you that a market for our common stock will develop or be sustained after this offering. Future sales of our common stock in the public market, including shares issued upon exercise of outstanding or options, or the availability of such shares for sale in the public market, could adversely affect the trading price of our common stock. As described below, only a limited number of shares will be available for sale by our existing stockholders shortly after this offering due to contractual and legal restrictions on resale. Sales of our common stock in the public market after such restrictions lapse, or the perception that those sales may occur, could adversely affect the trading price of our common stock at such time and our ability to raise equity capital in the future.
 
Based on           shares of common stock outstanding as of          , 2011, upon completion of this offering, shares of common stock will be outstanding, reflecting          shares of common stock sold in this offering and assuming no exercise of the underwriters’ option to purchase additional shares of common stock. All of the shares sold in this offering (including any shares sold upon the underwriters’ exercise of their option to purchase additional shares) will be freely tradable, except that any shares purchased in this offering by our affiliates, as that term is defined in Rule 144 under the Securities Act, generally may be sold in the public market only in compliance with Rule 144 under the Securities Act. The remaining           shares of common stock will be deemed restricted securities as that term is defined in Rule 144 under the Securities Act. These restricted securities are eligible for public sale only if they are registered under the Securities Act or if they qualify for an exemption from registration under Rule 144 or Rule 701 under the Securities Act, which are summarized below. In addition, substantially all of these restricted securities will be subject to the lock-up agreements described below.
 
Subject to the lock-up agreements described below and the provisions of Rules 144 and 701 under the Securities Act, these restricted securities will be available for sale in the public market as follows:
 
         
Date
 
Number of Shares
 
On the date of this prospectus
                
Between 90 and 180 days (subject to extension) after the date of this prospectus
       
At various times beginning more than 180 days (subject to extension) after the date of this prospectus
       
 
In addition, of the           shares of our common stock that were subject to stock options outstanding as of          , 2011, options to purchase           shares of common stock were vested as of          , 2011 and will be eligible for sale 180 days following the effective date of this offering, subject to extension as described in the section entitled “Underwriting”.
 
Rule 144
 
In general, under Rule 144 under the Securities Act, as in effect on the date of this prospectus, a person who is one of our affiliates and has beneficially owned shares of our common stock for at least six months would be entitled to sell within any three-month period, beginning on the date 90 days after the date of this prospectus, a number of shares that does not exceed the greater of:
 
  •  one percent of the number of shares of common stock then outstanding, which will equal approximately           shares immediately after the completion of this offering; or
 
  •  the average weekly trading volume of our common stock on the Nasdaq Global Market during the four calendar weeks preceding the filing of a notice on Form 144 with respect to the sale.
 
Sales under Rule 144 by our affiliates or persons selling shares on behalf of our affiliates are also subject to a certain manner of sale provisions and notice requirements and to the availability of current public information about us.
 
In general, under Rule 144 under the Securities Act, as in effect on the date of this prospectus, a person who is not deemed to have been one of our affiliates at any time during the three months preceding a sale, and who has beneficially owned the shares proposed to be sold for at least six


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months, including the holding period of any prior owner other than an affiliate, is entitled to sell the shares beginning on the 91st day after the date of this prospectus without complying with the manner of sale, volume limitation or notice provisions of Rule 144, and will be subject only to the public information requirements of Rule 144. If such person has beneficially owned the shares proposed to be sold for at least one year, including the holding period of any prior owner other than our affiliates, then such person is entitled to sell such shares without complying with any of the requirements of Rule 144.
 
Rule 701
 
Any of our employees, officers, directors or consultants who purchased shares under a written compensatory plan or contract may be entitled to sell them in reliance on Rule 701. Rule 701 permits affiliates to sell their Rule 701 shares under Rule 144 without complying with the holding period requirements of Rule 144. Rule 701 further provides that non-affiliates may sell these shares in reliance on Rule 144 without complying with the holding period, public information, volume limitation or notice provisions of Rule 144. All holders of Rule 701 shares are required to wait until 90 days after the date of this prospectus before selling those shares. However, substantially all of the shares issued under Rule 701 are subject to the lock-up agreements described below and will only become eligible for sale when the lock-up period expires.
 
As of          2011, shares of our outstanding common stock had been issued in reliance on Rule 701 as a result of exercise of stock options. These shares will be eligible for resale in reliance on this rule upon expiration of the lock-up agreements described below.
 
Lock-Up Agreements
 
In connection with this offering, we and each of our directors and officers and holders of substantially all of our outstanding common stock and holders of securities exercisable for or convertible into our common stock outstanding immediately prior to the completion of this offering, will agree that, without the prior written consent of Goldman, Sachs & Co., we and they will not offer, sell, contract to sell, pledge, grant any option to purchase, make any short sale or otherwise dispose of any shares of common stock, options or warrants to purchase shares of common stock or securities convertible into, exchangeable for or that represent the right to receive shares of common stock, whether now owned or hereafter acquired, during the period from the date of this prospectus and ending on the date 180 days after the date of this prospectus (as such period may be extended under certain circumstances). These restrictions are subject to certain exceptions, as described in more detail under “Underwriting” in this prospectus.
 
Registration Rights
 
We are party to an investor rights agreement which provides that certain stockholders have the right to demand that we file a registration statement or request that their shares of our common stock be covered by a registration statement that we are otherwise filing. See “Description of Capital Stock — Registration Rights” in this prospectus. Registration of their shares under the Securities Act would result in these shares becoming freely tradable without restriction under the Securities Act immediately upon effectiveness of the registration statement, subject to the expiration of the lock-up period described above and under “Underwriting” in this prospectus.
 
Stock Plans
 
As soon as practicable after the completion of this offering, we intend to file a Form S-8 registration statement under the Securities Act to register shares of our common stock reserved for issuance under our stock plan. This registration statement will become effective immediately upon filing, and shares covered by this registration statement will thereupon be eligible for sale in the public market, subject to Rule 144 limitations applicable to affiliates and any lock-up agreements. For a more complete discussion of our stock plans, see “Compensation Discussion and Analysis — Executive Compensation — Equity Compensation Plans”.


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MATERIAL UNITED STATES FEDERAL TAX CONSEQUENCES FOR NON-U.S. HOLDERS
 
The following discussion is a summary of the material U.S. federal tax consequences relating to the acquisition, ownership and disposition of our common stock by non-U.S. holders (as defined below). This discussion is based upon the provisions of the U.S. Internal Revenue Code of 1986, as amended, or the Code, U.S. Treasury regulations, rulings and judicial decisions, all as in effect on the date hereof. Those authorities may be changed, perhaps retroactively, so as to result in U.S. federal income and estate tax consequences different from those discussed below. There can be no assurance that the U.S. Internal Revenue Service, or the IRS, will agree with the statements herein.
 
A “U.S. holder” means a beneficial owner of our common stock that is for U.S. federal income tax purposes:
 
  •  a citizen or individual resident of the United States;
 
  •  a corporation or other entity treated as a corporation created or organized in or under the laws of the United States, any state thereof or the District of Columbia;
 
  •  an estate the income of which is subject to U.S. federal income taxation regardless of its source; or
 
  •  a trust, if (1) a court within the United States is able to exercise primary supervision over the trust’s administration and one or more U.S. persons (within the meaning of section 7701(a)(30) of the Code) have the authority to control all of its substantial decisions, or (2) a valid election to be treated as a U.S. person is in effect under the relevant Treasury regulations with respect to such trust.
 
A “non-U.S. holder” means a beneficial owner of our common stock that is neither a U.S. holder nor a partnership (including an entity that is treated as a partnership for U.S. federal income tax purposes).
 
This discussion deals only with our common stock held as capital assets within the meaning of Section 1221 of the Code (generally, property held for investment). This discussion does not address all of the U.S. federal income and estate tax consequences that may be relevant to a non-U.S. holder in light of such holder’s own particular circumstances, nor does it deal with special situations, such as:
 
  •  tax consequences to non-U.S. holders who may be subject to special tax treatment, such as banks and other financial institutions, insurance companies, partnerships or other entities treated as pass-through entities for U.S. federal income tax purposes, certain former citizens or residents of the United States, “controlled foreign corporations”, “passive foreign investment companies”, corporations that accumulate earnings to avoid U.S. federal income tax, tax-exempt entities, common trust funds, certain trusts, hybrid entities, foreign governments, international organizations and dealers or traders in securities that elect to use a mark-to-market method of accounting for their securities holdings;
 
  •  tax consequences to persons holding our common stock as part of a hedging, integrated, constructive sale or conversion transaction or a straddle;
 
  •  any gift tax consequences;
 
  •  alternative minimum tax consequences, if any; or
 
  •  any U.S. state or local or foreign tax consequences.
 
If an entity treated as a partnership for U.S. federal income tax purposes holds our common stock, the tax treatment of a partner in the partnership generally will depend upon the status of the partner and the activities of the partnership. Prospective investors that are entities treated as partnerships for U.S. federal income tax purposes should consult their own tax advisors regarding the U.S. federal income and estate tax considerations to them and their partners of holding our common stock.
 
THIS DISCUSSION IS FOR GENERAL PURPOSES ONLY. IF YOU ARE CONSIDERING THE ACQUISITION OF OUR COMMON STOCK, YOU SHOULD CONSULT YOUR OWN TAX ADVISORS CONCERNING THE U.S. FEDERAL INCOME AND ESTATE TAX CONSEQUENCES TO YOU IN


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LIGHT OF YOUR OWN PARTICULAR CIRCUMSTANCES, AS WELL AS ANY TAX CONSEQUENCES ARISING UNDER THE LAWS OF ANY OTHER TAXING JURISDICTION, THE EFFECT OF ANY CHANGES IN APPLICABLE TAX LAW, AND YOUR ENTITLEMENT TO BENEFITS UNDER AN APPLICABLE INCOME TAX TREATY.
 
Dividends on Common Stock
 
We do not expect to declare or pay any dividends on our common stock in the foreseeable future. If we make a distribution of cash or other property (other than certain pro rata distributions of our common stock) in respect of our common stock, the distribution will be treated as a dividend to the extent it is paid from our current or accumulated earnings and profits (as determined under U.S. federal income tax principles). If the amount of a distribution exceeds our current and accumulated earnings and profits, such excess first will be treated as a tax-free return of capital to the extent of the non-U.S. holder’s adjusted tax basis in our common stock, and thereafter will be treated as capital gain. Distributions treated as dividends on our common stock held by a non-U.S. holder generally will be subject to U.S. federal withholding tax at a rate of 30%, or at a lower rate if provided by an applicable income tax treaty and the non-U.S. holder has provided the documentation required to claim benefits under such treaty. Generally, to claim the benefits of an income tax treaty, a non-U.S. holder will be required to provide a properly executed IRS Form W-8BEN (or appropriate substitute or successor form) certifying its entitlement to benefits under the treaty.
 
If, however, a dividend is effectively connected with the conduct of a trade or business in the United States by the non-U.S. holder (and, if an applicable tax treaty so provides, is attributable to a permanent establishment or fixed base maintained by the non-U.S. holder in the United States), the dividend will not be subject to U.S. federal withholding tax (so long as the non-U.S. holder has provided the appropriate documentation, generally an IRS Form W-8ECI (or appropriate substitute or successor form), to the withholding agent), but the non-U.S. holder generally will be subject to U.S. federal income tax in respect of the dividend on a net income basis at regular U.S. federal income tax rates in substantially the same manner as U.S. persons. Dividends received by a non-U.S. holder that is a corporation for U.S. federal income tax purposes and which are effectively connected with the conduct of a U.S. trade or business (and, if an applicable tax treaty so provides, is attributable to a permanent establishment or fixed base maintained by the non-U.S. holder in the United States) may also be subject to a branch profits tax at the rate of 30% (or a lower rate if provided by an applicable tax treaty).
 
A non-U.S. holder that is eligible for a reduced rate of U.S. federal withholding tax under an income tax treaty may obtain a refund or credit of any excess amounts withheld by timely filing an appropriate claim for a refund together with the required information with the IRS.
 
Sale, Exchange or Other Disposition of Common Stock
 
Subject to the discussion of backup withholding below, a non-U.S. holder generally will not be subject to U.S. federal income tax (including withholding tax) on gain realized on the sale, exchange or other disposition of our common stock unless:
 
  •  such non-U.S. holder is an individual who is present in the United States for 183 days or more in the taxable year of such sale, exchange or disposition, and certain other conditions are met;
 
  •  such gain is effectively connected with the conduct by the non-U.S. holder of a trade or business in the United States (and, if an applicable tax treaty so provides, is attributable to a permanent establishment or a fixed base maintained by the non-U.S. holder in the United States); or
 
  •  we are or have been a “United States real property holding corporation”, or a USRPHC, for U.S. federal income tax purposes at any time during the shorter of the five-year testing period ending on the date of such disposition and the non-U.S. holder’s holding period of our common stock, and certain other conditions are met.


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Gain realized by a non-U.S. holder that is effectively connected with such non-U.S. holder’s conduct of a trade or business in the United States generally will be subject to U.S. federal income tax on a net income basis at regular U.S. federal income tax rates in substantially the same manner as a U.S. person (except as provided by an applicable tax treaty). In addition, if such non-U.S. holder is a corporation for U.S. federal income tax purposes, it may also be subject to a branch profits tax at the rate of 30% (or a lower rate if provided by an applicable tax treaty).
 
Generally, a corporation is a USRPHC if the fair market value of its “United States real property interests” equals or exceeds 50% of the sum of the fair market value of its worldwide (domestic and foreign) real property interests and its other assets used or held for use in a trade or business (all as determined for U.S. federal income tax purposes). For this purpose, real property interests include land, improvements and associated personal property. We believe that we are not currently a USRPHC for this purpose. If we were a USRPHC during the applicable testing period, non-U.S. holders owning (directly or indirectly) more than 5% of our common stock generally would be subject to U.S. federal income tax on the gain realized on the sale, exchange or disposition of our common stock, which would be treated as income effectively connected with a U.S. trade or business (and taxable as discussed above). Even if we were a USRPHC during the testing period, U.S. federal income tax would not apply to gain realized on the sale, exchange or disposition of our common stock by a non-U.S. holder that owns (directly or indirectly) 5% or less of our common stock so long as our common stock is “regularly traded on an established securities market” within the meaning of the applicable U.S. Treasury regulations. Prospective investors should be aware that no assurance can be provided that our common stock will be so regularly traded when a non-U.S. holder sells our common stock.
 
Information Reporting and Backup Withholding
 
Dividends and proceeds from the sale, exchange or other disposition of our common stock are potentially subject to backup withholding at the applicable rate. In general, backup withholding will not apply to dividends on our common stock paid by us or our paying agents, in their capacities as such, to a non-U.S. holder if the holder has provided the required certification that it is a non-U.S. holder, such as by providing an IRS Form W-8BEN or IRS Form W-8ECI (or appropriate substitute or successor form) and neither we nor our paying agent has actual knowledge (or reason to know) that the holder is a U.S. holder that is not an exempt recipient.
 
Backup withholding is not an additional tax. Any amounts withheld under the backup withholding rules will be allowed as a refund or a credit against a non-U.S. holder’s U.S. federal income tax liability, provided the required information is furnished on a timely basis to the IRS.
 
Non-U.S. holders should consult their tax advisors regarding the application of the information reporting and backup withholding rules to them.
 
Recent Legislation Imposing Additional Disclosure Requirements on Holders that are Foreign Entities
 
Non-U.S. holders should be aware of recently enacted legislation that, beginning on January 1, 2013, will impose a 30% withholding tax on certain payments (which could include dividends in respect of our common stock and gross proceeds from the sale, exchange or other disposition of our common stock) made to a foreign entity if such entity fails to satisfy certain disclosure requirements. Various requirements and exceptions are provided under the legislation and additional requirements and exceptions may be provided in subsequent guidance. Non-U.S. holders should consult their own tax advisors regarding the potential application and impact of the new requirements based upon their particular circumstances.
 
U.S. Federal Estate Tax
 
Common stock owned or treated as owned by an individual who is not a citizen or resident of the United States (as specifically defined for U.S. federal estate tax purposes) at the time of death will be included in the individual’s gross estate for U.S. federal estate tax purposes and may be subject to U.S. federal estate tax unless an applicable estate tax treaty provides otherwise.


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UNDERWRITING
 
We and the underwriters named below have entered into an underwriting agreement with respect to the shares being offered. Subject to certain conditions, each underwriter has severally agreed to purchase the number of shares indicated in the following table. Goldman, Sachs & Co. and Barclays Capital Inc. are the representatives of the underwriters.
 
         
    Number of
Underwriters
 
Shares
 
Goldman, Sachs & Co. 
                
Barclays Capital Inc. 
       
         
Total
       
         
 
The underwriters are committed to take and pay for all of the shares being offered, if any are taken, other than the shares covered by the option described below unless and until this option is exercised.
 
If the underwriters sell more shares than the total number set forth in the table above, the underwriters have an option to buy up to an additional           shares from us to cover such sales. They may exercise that option for 30 days. If any shares are purchased pursuant to this option, the underwriters will severally purchase shares in approximately the same proportion as set forth in the table above.
 
The following table shows the per share and total underwriting discounts and commissions to be paid to the underwriters by us. Such amounts are shown assuming both no exercise and full exercise of the underwriters’ option to purchase           additional shares.
 
                 
Paid by the Company
   
No Exercise
 
Full Exercise
 
Per Share
  $           $        
Total
  $       $  
 
Shares sold by the underwriters to the public will initially be offered at the initial public offering price set forth on the cover of this prospectus. Any shares sold by the underwriters to securities dealers may be sold at a discount of up to $      per share from the initial public offering price. If all the shares are not sold at the initial public offering price, the representatives may change the offering price and the other selling terms. The offering of the shares by the underwriters is subject to receipt and acceptance and subject to the underwriters’ right to reject any order in whole or in part.
 
The Company and its officers, directors, and holders of substantially all of our common stock and holder of securities exercisable for or convertible into our common stock will agree with the underwriters, subject to certain exceptions, not to dispose of or hedge any of their common stock or securities convertible into or exchangeable for shares of common stock during the period from the date of this prospectus continuing through the date 180 days after the date of this prospectus, except with the prior written consent of Goldman, Sachs & Co. This agreement does not apply to any existing employee benefit plans. See “Shares Eligible for Future Sale” for a discussion of certain transfer restrictions.
 
The 180-day restricted period described in the preceding paragraph will be automatically extended if: (1) during the last 17 days of the 180-day restricted period we issue an earnings release or announce material news or a material event; or (2) prior to the expiration of the 180-day restricted period, we announce that we will release earnings results during the 15-day period following the last day of the 180-day period, in which case the restrictions described in the preceding paragraph will continue to apply until the expiration of the 18-day period beginning on the issuance of the earnings release of the announcement of the material news or material event.


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Prior to the offering, there has been no public market for the shares. The initial public offering price has been negotiated among us and the representatives. Among the factors to be considered in determining the initial public offering price of the shares, in addition to prevailing market conditions, will be our historical performance, estimates of the business potential and earnings prospects of our company, an assessment of our management and the consideration of the above factors in relation to market valuation of companies in related businesses.
 
We intend to apply to list our common stock on the Nasdaq Global Market under the symbol “CERE”.
 
In connection with the offering, the underwriters may purchase and sell shares of common stock in the open market. These transactions may include short sales, stabilizing transactions and purchases to cover positions created by short sales. Shorts sales involve the sale by the underwriters of a greater number of shares than they are required to purchase in the offering. “Covered” short sales are sales made in an amount not greater than the underwriters’ option to purchase additional shares from us in the offering. The underwriters may close out any covered short position by either exercising their option to purchase additional shares or purchasing shares in the open market. In determining the source of shares to close out the covered short position, the underwriters will consider, among other things, the price of shares available for purchase in the open market as compared to the price at which they may purchase additional shares pursuant to the option granted to them. “Naked” short sales are any sales in excess of such option. The underwriters must close out any naked short position by purchasing shares in the open market. A naked short position is more likely to be created if the underwriters are concerned that there may be downward pressure on the price of the common stock in the open market after pricing that could adversely affect investors who purchase in the offering. Stabilizing transactions consist of various bids for or purchases of common stock made by the underwriters in the open market prior to the completion of the offering.
 
The underwriters may also impose a penalty bid. This occurs when a particular underwriter repays to the underwriters a portion of the underwriting discount received by it because the representatives have repurchased shares sold by or for the account of such underwriter in stabilizing or short covering transactions.
 
Purchases to cover a short position and stabilizing transactions, as well as other purchases by the underwriters for their own accounts, may have the effect of preventing or retarding a decline in the market price of our stock, and together with the imposition of the penalty bid, may stabilize, maintain or otherwise affect the market price of our common stock. As a result, the price of our common stock may be higher than the price that otherwise might exist in the open market. If these activities are commenced, they may be discontinued at any time. These transactions may be effected on the Nasdaq Global Market, in the over-the-counter market or otherwise.
 
The underwriters do not expect sales to discretionary accounts to exceed five percent of the total number of shares offered.
 
We estimate that our share of the total expenses of the offering, excluding underwriting discounts and commissions, will be approximately $      .
 
We have agreed to indemnify the several underwriters against certain liabilities, including liabilities under the Securities Act.
 
The underwriters and their respective affiliates are full service financial institutions engaged in various activities, which may include securities trading, commercial and investment banking, financial advisory, investment management, investment research, principal investment, hedging, financing and brokerage activities. Certain of the underwriters and their respective affiliates have, from time to time, performed, and may in the future perform, various financial advisory and investment banking services for the issuer, for which they received or will receive customary fees and expenses.


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In the ordinary course of their various business activities, the underwriters and their respective affiliates may make or hold a broad array of investments and actively trade debt and equity securities (or related derivative securities) and financial instruments (including bank loans) for their own account and for the accounts of their customers and such investment and securities activities may involve securities and instruments of the issuer. The underwriters and their respective affiliates may also make investment recommendations and/or publish or express independent research views in respect of such securities or instruments and may at any time hold, or recommend to clients that they acquire, long and/or short positions in such securities and instruments.
 
Selling Restrictions
 
In relation to each Member State of the European Economic Area which has implemented the Prospectus Directive (each, a Relevant Member State), each underwriter has represented and agreed that with effect from and including the date on which the Prospectus Directive is implemented in that Relevant Member State (the Relevant Implementation Date) it has not made and will not make an offer of shares to the public in that Relevant Member State prior to the publication of a prospectus in relation to the shares which has been approved by the competent authority in that Relevant Member State or, where appropriate, approved in another Relevant Member State and notified to the competent authority in that Relevant Member State, all in accordance with the Prospectus Directive, except that it may, with effect from and including the Relevant Implementation Date, make an offer of shares to the public in that Relevant Member State at any time:
 
• to legal entities which are authorized or regulated to operate in the financial markets or, if not so authorized or regulated, whose corporate purpose is solely to invest in securities;
 
• to any legal entity which has two or more of (1) an average of at least 250 employees during the last financial year; (2) a total balance sheet of more than €43,000,000 and (3) an annual net turnover of more than €50,000,000, as shown in its last annual or consolidated accounts;
 
• to fewer than 100 natural or legal persons (other than qualified investors as defined in the Prospectus Directive) subject to obtaining the prior consent of the representatives for any such offer; or
 
• in any other circumstances which do not require the publication by the Issuer of a prospectus pursuant to Article 3 of the Prospectus Directive.
 
For the purposes of this provision, the expression an “offer of shares to the public” in relation to any shares in any Relevant Member State means the communication in any form and by any means of sufficient information on the terms of the offer and the shares to be offered so as to enable an investor to decide to purchase or subscribe the shares, as the same may be varied in that Relevant Member State by any measure implementing the Prospectus Directive in that Relevant Member State and the expression Prospectus Directive means Directive 2003/71/EC and includes any relevant implementing measure in each Relevant Member State.
 
Each underwriter has represented and agreed that:
 
• it has only communicated or caused to be communicated and will only communicate or cause to be communicated an invitation or inducement to engage in investment activity (within the meaning of Section 21 of the FSMA) received by it in connection with the issue or sale of the shares in circumstances in which Section 21(1) of the FSMA does not apply to the Issuer; and
 
• it has complied and will comply with all applicable provisions of the FSMA with respect to anything done by it in relation to the shares in, from or otherwise involving the United Kingdom.
 
The shares may not be offered or sold by means of any document other than (i) in circumstances which do not constitute an offer to the public within the meaning of the Companies Ordinance (Cap.32, Laws of Hong Kong), or (ii) to “professional investors” within the meaning of the Securities


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and Futures Ordinance (Cap.571, Laws of Hong Kong) and any rules made thereunder, or (iii) in other circumstances which do not result in the document being a “prospectus” within the meaning of the Companies Ordinance (Cap.32, Laws of Hong Kong), and no advertisement, invitation or document relating to the shares may be issued or may be in the possession of any person for the purpose of issue (in each case whether in Hong Kong or elsewhere), which is directed at, or the contents of which are likely to be accessed or read by, the public in Hong Kong (except if permitted to do so under the laws of Hong Kong) other than with respect to shares which are or are intended to be disposed of only to persons outside Hong Kong or only to “professional investors” within the meaning of the Securities and Futures Ordinance (Cap. 571, Laws of Hong Kong) and any rules made thereunder.
 
This prospectus has not been registered as a prospectus with the Monetary Authority of Singapore. Accordingly, this prospectus and any other document or material in connection with the offer or sale, or invitation for subscription or purchase, of the shares may not be circulated or distributed, nor may the shares be offered or sold, or be made the subject of an invitation for subscription or purchase, whether directly or indirectly, to persons in Singapore other than (i) to an institutional investor under Section 274 of the Securities and Futures Act, Chapter 289 of Singapore, or the SFA, (ii) to a relevant person, or any person pursuant to Section 275(1A), and in accordance with the conditions, specified in Section 275 of the SFA or (iii) otherwise pursuant to, and in accordance with the conditions of, any other applicable provision of the SFA.
 
Where the shares are subscribed or purchased under Section 275 by a relevant person which is: (a) a corporation (which is not an accredited investor) the sole business of which is to hold investments and the entire share capital of which is owned by one or more individuals, each of whom is an accredited investor; or (b) a trust (where the trustee is not an accredited investor) whose sole purpose is to hold investments and each beneficiary is an accredited investor, shares, debentures and units of shares and debentures of that corporation or the beneficiaries’ rights and interest in that trust shall not be transferable for 6 months after that corporation or that trust has acquired the shares under Section 275 except: (1) to an institutional investor under Section 274 of the SFA or to a relevant person, or any person pursuant to Section 275(1A), and in accordance with the conditions, specified in Section 275 of the SFA; (2) where no consideration is given for the transfer; or (3) by operation of law.
 
The securities have not been and will not be registered under the Financial Instruments and Exchange Law of Japan, or the Financial Instruments and Exchange Law, and each underwriter has agreed that it will not offer or sell any securities, directly or indirectly, in Japan or to, or for the benefit of, any resident of Japan (which term as used herein means any person resident in Japan, including any corporation or other entity organized under the laws of Japan), or to others for re-offering or resale, directly or indirectly, in Japan or to a resident of Japan, except pursuant to an exemption from the registration requirements of, and otherwise in compliance with, the Financial Instruments and Exchange Law and any other applicable laws, regulations and ministerial guidelines of Japan.


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LEGAL MATTERS
 
The validity of the shares of common stock offered hereby will be passed upon for us by Shearman & Sterling LLP, New York, New York. Simpson Thacher & Bartlett LLP, Palo Alto, California is acting as counsel to the underwriters.
 
EXPERTS
 
The consolidated financial statements as of December 31, 2008 and August 31, 2009 and 2010 and for each of the years ended December 31, 2007 and 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010 included in this prospectus have been included herein in reliance on the report of KPMG LLP, an independent registered public accounting firm, appearing elsewhere herein, and upon the authority of said firm as experts in auditing and accounting.
 
WHERE YOU CAN FIND ADDITIONAL INFORMATION
 
We have filed a registration statement on Form S-1 with the SEC covering the shares of our common stock we are offering by this prospectus. This prospectus does not include all of the information contained in the registration statement. You should refer to the registration statement and its exhibits for additional information. Whenever we make reference in this prospectus to any of our contracts, agreements or other documents, the references are not necessarily complete and you should refer to the exhibits filed as part of the registration statement for copies of the actual contract, agreement or other document. After this offering, we will file annual, quarterly and special reports, proxy statements and other information with the SEC.
 
You can obtain copies of our SEC filings, including the registration statement, over the Internet at the SEC’s web site at www.sec.gov. You may also read and copy any document we file with the SEC at its public reference facilities at 100 F Street, N.E. Room 1580, Washington, D.C. 20549. You may also obtain copies of the documents at prescribed rates by writing to the Public Reference Section of the SEC at 100 F Street, NE, Washington, D.C. 20549. Please call the SEC at 1-800-SEC-0330 for further information on the operation of the public reference facilities.


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REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
 
The Board of Directors and Stockholders
Ceres, Inc.:
 
We have audited the accompanying consolidated balance sheets of Ceres, Inc. and subsidiaries as of December 31, 2008, August 31, 2009 and August 31, 2010, and the related consolidated statements of operations, stockholders’ deficit and cash flows for the years ended December 31, 2007 and December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010. These consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on these consolidated financial statements based on our audits.
 
We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.
 
In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of Ceres, Inc. and subsidiaries as of December 31, 2008, August 31, 2009 and August 31, 2010, and the results of their operations and their cash flows for the years ended December 31, 2007 and December 31, 2008, the eight months ended August 31, 2009 and the year ended August 31, 2010, in conformity with U.S. generally accepted accounting principles.
 
As discussed in note 1(n) to the consolidated financial statements, effective January 1, 2009, the Company changed the accounting treatment for certain warrants upon adoption of a new accounting standard. As discussed in note 1(o) to the consolidated financial statements, effective for all periods presented, the Company changed the manner in which it accounted for convertible preferred stock.
 
/s/  KPMG LLP
 
Los Angeles, California
February 4, 2011, except as related
to note 1(o) to the consolidated
financial statements which is as
of May 19, 2011


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CERES, INC.

Consolidated Balance Sheets
(Information as of February 28, 2011 is unaudited)

(In thousands, except share and per share amounts)
 
                                         
                            Pro Forma
 
    December 31,
    August 31,     February 28,
    February 28,
 
    2008     2009     2010     2011     2011  
                      (Unaudited)     (Unaudited)  
 
Assets
                                       
Current assets:
                                       
Cash and cash equivalents
  $ 12,145     $ 14,960     $ 33,055     $ 22,489     $ 22,489  
Restricted investment
    100       100                    
Investments
    29,051       15,384                    
Prepaid expenses
    884       992       675       612       612  
Accounts receivable
    1,736       449       1,196       1,191       1,191  
Other current assets
    635       53       64       178       178  
                                         
Total current assets
    44,551       31,938       34,990       24,470       24,470  
                                         
Property and equipment, net
    8,847       8,884       8,452       7,551       7,551  
Restricted cash and investment
    100             3,000       3,000       3,000  
Investments
    4,035                          
Other assets
    185       272       206       192       192  
                                         
Total long-term assets
    13,167       9,156       11,658       10,743       10,743  
                                         
Total assets
  $ 57,718     $ 41,094     $ 46,648     $ 35,213     $ 35,213  
                                         
Liabilities, Convertible Preferred Stock and Stockholders’ (Deficit) Equity
                                       
Current liabilities:
                                       
Accounts payable and accrued expenses
  $ 3,152     $ 4,072     $ 3,774     $ 3,924     $ 3,924  
Deferred revenue
          257       678       777       777  
Deferred rent
    31       31       31       31       31  
Current portion of long-term debt
    71       35       2,182       2,178       2,178  
                                         
Total current liabilities
    3,254       4,395       6,665       6,910       6,910  
Deferred rent
    261       241       201       175       175  
Long-term debt, net of current portion
    16       12       4,198       3,109       3,109  
Preferred Stock warrant liabilities
    13       13       333       331        
Common Stock warrant liabilities
          2,931       8,578       8,666        
                                         
Total liabilities
    3,544       7,592       19,975       19,191       10,194  
                                         
Commitments and contingencies
                                       
Convertible preferred stock
                                       
Series A Convertible Preferred Stock, $0.01 par value; 6,733,875 shares authorized, issued, and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $6,734
    6,734       6,734       6,734       6,734        
Series B Convertible Preferred Stock, $0.01 par value; 4,755,313 shares authorized; 3,640,000 shares issued and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $7,280
    7,280       7,280       7,280       7,280        
Series C Convertible Preferred Stock, $0.01 par value; 14,550,000 shares authorized; 12,405,418 shares issued and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $49,622
    49,622       49,622       49,622       49,622        
Series C-1 Convertible Preferred Stock, $0.01 par value; 2,264,681 shares authorized; 2,181,796 shares issued and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011(unaudited); aggregate liquidation preference of $8,727
    8,520       8,520       8,520       8,520        
Series D Convertible Preferred Stock, $0.01 par value; 4,583,335 shares authorized; 3,150,012 shares issued and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $18,900
    18,563       18,563       18,563       18,563        
Series E Convertible Preferred Stock, $0.01 par value; 3,351,794 shares authorized; 3,333,333 shares issued and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $21,667
    21,667       21,667       21,667       21,667        
Series F Convertible Preferred Stock, $0.01 par value; 11,538,462 shares authorized, issued, and outstanding at December 31, 2008 and August 31, 2009 and 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $75,000
    70,693       70,693       70,693       70,693        
Series G Convertible Preferred Stock, $0.01 par value; 3,076,923 shares authorized, issued, and outstanding at August 31, 2010 and February 28, 2011 (unaudited); aggregate liquidation preference of $20,000
                14,423       14,423        
                                         
Total convertible preferred stock
    183,079       183,079       197,502       197,502        
                                         
Stockholders’ (deficit) equity:
                                       
Common Stock, $0.01 par value; 75,000,000 shares authorized; 5,592,917, 5,698,417, 5,844,417, and 5,930,417 shares issued and outstanding at December 31, 2008, August 31, 2009 and 2010 and February 28, 2011 (unaudited), respectively; 51,990,236 shares issued and outstanding pro forma at February 28, 2011 (unaudited)
    56       57       58       59       520  
Additional paid-in capital
    6,484       4,110       5,440       6,069       212,107  
Accumulated deficit
    (135,445 )     (153,744 )     (176,327 )     (187,608 )     (187,608 )
                                         
Total stockholders’ (deficit) equity
    (128,905 )     (149,577 )     (170,829 )     (181,480 )     25,019  
                                         
Total liabilities, convertible preferred stock and stockholders’ (deficit) equity
  $ 57,718     $ 41,094     $ 46,648     $ 35,213     $ 35,213  
                                         
 
See accompanying notes to the consolidated financial statements.


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CERES, INC.
 
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share amounts)
 
                                                 
                Eight
                   
    Year Ended
    Months Ended
    Year Ended
    Six Months Ended
 
    December 31,     August 31,
    August 31,
    February 28,  
    2007     2008     2009     2010     2010     2011  
                            (Unaudited)  
 
Revenues:
                                               
Product sales
  $     $ 64     $ 98     $ 288     $ 5     $ 9  
Collaborative research and government grants
    7,180       3,880       2,328       6,326       2,497       3,320  
                                                 
Total revenues
    7,180       3,944       2,426       6,614       2,502       3,329  
                                                 
Cost and operating expenses:
                                               
Cost of product sales
          3,777       2,690       2,946       1,424       1,330  
Research and development
    19,220       20,309       12,397       16,697       8,516       8,641  
Selling, general and administrative
    9,811       8,784       6,645       9,207       4,237       4,339  
                                                 
Total cost and operating expenses
    29,031       32,870       21,732       28,850       14,177       14,310  
                                                 
Loss from operations
    (21,851 )     (28,926 )     (19,306 )     (22,236 )     (11,675 )     (10,981 )
Interest expense
    (123 )           (5 )     (153 )     (3 )     (248 )
Interest income
    1,521       2,001       243       23       20       34  
Other income (expense)
    5             161       (152 )     (64 )     (85 )
                                                 
Loss before income taxes
    (20,448 )     (26,925 )     (18,907 )     (22,518 )     (11,722 )     (11,280 )
Income tax benefit (expense)
    (7 )     148       211       (65 )     (1 )     (1 )
                                                 
Net Loss
  $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
                                                 
Basic and diluted net loss per share attributable to common stockholders
  $ (3.84 )   $ (4.89 )   $ (3.33 )   $ (3.90 )   $ (2.04 )   $ (1.91 )
Weighted average outstanding common shares used for net loss per share attributable to common stockholders:
                                               
Basic and diluted
    5,323,259       5,473,090       5,621,671       5,791,443       5,751,539       5,900,947  
                                                 
Pro forma net loss per share:
                                               
Basic and diluted (unaudited)
                          $ (0.46 )           $ (0.22 )
                                                 
Weighted average outstanding common shares used in computing pro forma net loss per share:
                                               
Basic and diluted (unaudited)
                            49,339,144               51,960,766  
                                                 
 
See accompanying notes to the consolidated financial statements.


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CERES, INC.
 
(Information for the six months ended February 28, 2011 is unaudited)
(In thousands, except share amounts)
 
                                         
    Common Stock     Additional
          Total
 
    Number of
          Paid-in
    Accumulated
    Stockholders’
 
    Shares     Amount     Capital     Deficit     Deficit  
 
Balance at December 31, 2006
    5,156,583     $ 52     $ 980     $ (88,213 )   $ (87,181 )
Exercise of common stock options
    214,037       2       60             62  
Stock compensation expense
                727             727  
Issuance of common stock warrants
                3,489             3,489  
Net loss
                      (20,455 )     (20,455 )
                                         
Balance at December 31, 2007
    5,370,620       54       5,256       (108,668 )     (103,358 )
Exercise of common stock options
    212,297       2       56             58  
Stock compensation expense
                1,172             1,172  
Restricted stock award issuance
    10,000                          
Net loss
                      (26,777 )     (26,777 )
                                         
Balance at December 31, 2008
    5,592,917       56       6,484       (135,445 )     (128,905 )
Cumulative effect of change in accounting principle (see Note 1(n))
                (3,489 )     397       (3,092 )
                                         
Adjusted balance January 1, 2009
    5,592,917       56       2,995       (135,048 )     (131,997 )
Exercise of common stock options
    105,500       1       33             34  
Stock compensation expense
                1,082             1,082  
Net loss
                      (18,696 )     (18,696 )
                                         
Balance at August 31, 2009
    5,698,417       57       4,110       (153,744 )     (149,577 )
Exercise of common stock options
    146,000       1       30             31  
Stock compensation expense
                1,300             1,300  
Net loss
                      (22,583 )     (22,583 )
                                         
Balance at August 31, 2010
    5,844,417       58       5,440       (176,327 )     (170,829 )
Exercise of common stock options (unaudited)
    86,000       1       34             35  
Stock compensation expense (unaudited)
                595             595  
Net loss (unaudited)
                      (11,281 )     (11,281 )
                                         
Balance at February 28, 2011 (unaudited)
    5,930,417     $ 59     $ 6,069     $ (187,608 )   $ (181,480 )
                                         
 
See accompanying notes to the consolidated financial statements.


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CERES, INC.

Consolidated Statements of Cash Flows
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands)
 
                                                 
                Eight
                   
    Year Ended
    Months Ended
    Year Ended
    Six Months Ended
 
    December 31,     August 31,
    August 31,
    February 28,  
    2007     2008     2009     2010     2010     2011  
                            (Unaudited)  
 
Cash flows from operating activities:
                                               
Net loss
  $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
Adjustments to reconcile net loss to net cash used in operating activities:
                                               
Change in fair value of common and preferred
                                               
stock warrants
    (14 )           (162 )     152       64       85  
Net gain on disposal of assets
                      106              
Depreciation
    1,935       2,167       1,548       2,420       1,204       1,106  
Stock compensation
    727       1,172       1,082       1,300       612       595  
Discount on matured investments
    59       12       (111 )     19       19        
Changes in operating assets and liabilities:
                                               
Prepaid expenses
    (253 )     342       (107 )     316       77       63  
Accounts receivable
    8,798       (1,521 )     1,286       (745 )     (323 )     4  
Other assets
    (976 )     544       495       86       (312 )     (100 )
Accounts payables and accrued expenses
    1,151       (808 )     920       (298 )     (808 )     182  
Deferred revenue
    (995 )     (5 )     257       420       929       100  
Deferred rent
    (9 )     (25 )     (20 )     (39 )     (15 )     (26 )
                                                 
Net cash used in operating activities
    (10,032 )     (24,899 )     (13,508 )     (18,846 )     (10,276 )     (9,272 )
                                                 
Cash flows from investing activities:
                                               
Purchases of property and equipment
    (2,283 )     (3,812 )     (1,585 )     (2,093 )     (1,312 )     (204 )
Change in restricted cash and investments
    100       2,600       100       (2,900 )     (1,500 )      
Purchased investments (at cost)
    (58,080 )     (49,443 )     (30,341 )                  
Unrealized gains from investments
          111       (19 )                  
Maturities of investments
    6,446       73,977       48,174       15,365       15,365        
                                                 
Net cash (used in) provided by investing activities
    (53,817 )     23,433       16,329       10,372       12,553       (204 )
                                                 
Cash flows from financing activities:
                                               
Principal payments on other long term debt
    (1,474 )     (311 )     (40 )     (12 )     (3 )     (7 )
Principal payments on equipment loan
                      (450 )           (1,117 )
Proceeds from issuance of debt and preferred
                                               
stock warrants
                      7,000       3,000        
Proceeds from issuance of convertible preferred
                                               
stock and common stock warrants
    74,182                   20,000              
Proceeds from exercise of warrants
    280                                
Proceeds from issuance of common stock
    62       59       34       31       18       34  
                                                 
Net cash provided by (used in) financing activities
    73,050       (252 )     (6 )     26,569       3,015       (1,090 )
                                                 
Net increase (decrease) in cash and cash equivalents
    9,201       (1,718 )     2,815       18,095       5,292       (10,566 )
Cash and cash equivalents at beginning of period
    4,662       13,863       12,145       14,960       14,960       33,055  
                                                 
Cash and cash equivalents at end of period
  $ 13,863     $ 12,145     $ 14,960     $ 33,055     $ 20,252     $ 22,489  
                                                 
Supplemental disclosure of cash flow information:
                                               
Cash paid during the year for interest
  $ 91     $ 17     $ 5     $ 110     $ 3     $ 207  
Cash paid during the year for income taxes
    31       1       1       1       1       1  
 
See accompanying notes to the consolidated financial statements


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
(1)   Summary of Significant Accounting Policies
 
(a)   Description of Business
 
Ceres, Inc. (the “Company”) is an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks that can enable the large-scale replacement of petroleum and other fossil fuels. The Company uses a combination of advanced plant breeding and biotechnology to develop dedicated energy crops.
 
In January 2010, the Company incorporated a subsidiary, Ceres Sementes do Brasil Ltda. The Company’s ownership in this subsidiary is 99.9% and the Company’s Chief Executive Officer owns the remaining interest.
 
(b)   Liquidity
 
The Company has incurred substantial net losses since its inception, including net losses of $20,455, $26,777, $18,696, and $22,583 for the years ended December 31, 2007 and 2008, eight months ended August 31, 2009, and the year ended August 31, 2010, respectively, and $11,723 and $11,281 for the six months ended February 28, 2010 and 2011 (unaudited), respectively. As of February 28, 2011 (unaudited), the Company had an accumulated deficit of $187,608.
 
The Company expects to incur additional losses related to the continued development and expansion of its business including research and development, seed production and operations, and sales and marketing. The Company is dependent on raising additional funding in the near term. While the Company raised $20,000 from the sale of convertible preferred stock and warrants to purchase common stock and borrowed $7,000 from a bank (see Note 5) in 2010, there is no assurance that the Company will be successful in raising any additional necessary financing in the future. There is also no assurance that profitable operations will be achieved, or if achieved, can be sustained on a continued basis.
 
Management believes that the current assets at August 31, 2010 are sufficient to fund operations at the current normalized spend rate into the first quarter of the Company’s fiscal year ending August 31, 2012. The Company has plans to raise additional financing from a variety of potential sources including existing investors, collaborations, government grants, public and private debt or equity financings. To the extent the Company is unable to raise additional funds in the near term, the Company has contingency plans in place to moderate the pace of planned expansion and reduce expenses related to the Company’s operations. These contingency plans would enable the Company to continue to operate its core business through the second quarter of fiscal 2012.
 
(c)   Principles of Consolidation
 
The consolidated financial statements include the financial statements of the Company and its subsidiary. All significant intercompany balances and transactions have been eliminated in consolidation.
 
(d)   Change in Fiscal Year-End
 
During 2009, the Company changed its fiscal year-end to August 31 from December 31 to better match the seasonality of the production and selling cycles related to the seed and traits business.
 
Any reference in the footnotes to the “2007”, “2008”, “2009” and “2010” periods represents consolidated statements of operations, stockholders’ deficit or cash flow activity for the years ended


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
December 31, 2007 and 2008, eight months ended August 31, 2009 and year ended August 31, 2010 or consolidated balance sheets as of December 31, 2008 and August 31, 2009 and August 31, 2010, respectively.
 
(e)   Unaudited Interim Financial Information
 
The consolidated balance sheet as of February 28, 2011, the consolidated statements of operations and cash flows for the six months ended February 28, 2010 and 2011, and the consolidated statements of stockholders’ deficit for the six months ended February 28, 2011 are unaudited. The amounts as of February 28, 2011 and for the six months ended February 28, 2010 and 2011 included within the notes to the consolidated financial statements are also unaudited. In the opinion of the Company’s management the unaudited consolidated financial statements have been prepared on the same basis as the annual consolidated financial statements and all adjustments (which include normal recurring adjustments) necessary for a fair presentation of financial position, results of operations and cash flows, and change in stockholders’ deficit at February 28, 2011 and for the six months ended February 28, 2010 and 2011 have been made. Interim results are not necessarily indicative of the results that will be achieved for the year, for any interim period, or for any future year.
 
(f)   Unaudited Pro Forma Balance Sheet and Net Loss Per Share
 
In May 2011, the Company’s board of directors approved the filing of a registration statement with the Securities and Exchange Commission for an initial public offering of the Company’s common stock. If the initial public offering is consummated, all of the convertible preferred stock outstanding will automatically convert into 46,059,819 shares of common stock, based on the shares of convertible preferred stock outstanding as of February 28, 2011, warrants to purchase common stock are assumed to net exercise to shares of common stock, and warrants to purchase convertible preferred stock will convert to warrants to purchase common stock.
 
The unaudited pro forma balance sheet gives effect to the conversion of 46,059,819 shares of convertible preferred stock and reclassification of the common and preferred stock warrant liabilities to additional paid-in capital as of February 28, 2011.
 
The unaudited pro forma basic and diluted net loss per common share for the year ended August 31, 2010 and the six-month period ended February 28, 2011 have been computed to give effect to the conversion of the Company’s convertible preferred stock (using the if-converted method) into common stock as though the conversion had occurred as of September 1, 2009.
 
(g)   Cash Equivalents
 
The Company considers all highly liquid investments, with an original maturity of three months or less when purchased, to be cash equivalents. Cash equivalents totaled of $11,817, $14,130, $13,019, and $13,019 at December 31, 2008, August 31, 2009, August 31, 2010 and February 28, 2011 (unaudited), respectively.
 
(h)   Restricted Cash and Restricted Investments
 
Cash and investment accounts that are restricted as to withdrawal or usage are presented as restricted cash and investments.


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
(i)   Investments
 
Investment securities primarily consisted of U.S. Treasury securities with maturities of 365 days or less. The securities were classified as held to maturity as the Company has the ability and intent to hold the securities until maturity. The securities were recorded at amortized cost, and adjusted for the amortization or accretion of premiums or discounts. All investment securities matured by August 31, 2010.
 
(j)   Financial Instruments
 
The carrying value of financial instruments such as cash and cash equivalents, receivables, accounts payable, and accrued expenses approximate their fair value due to the short-term nature of these instruments. At each period end, the fair value of the long-term debt approximated carrying value based on interest rates currently available to the Company.
 
(k)   Fair Value Measurements
 
The Company adopted Financial Accounting Standards Board (FASB) ASC Topic 820, Fair Value Measurements and Disclosures, on January 1, 2008 for fair value measurements of financial assets and financial liabilities that are recognized or disclosed at fair value in the financial statements on a recurring basis. On January 1, 2009, the Company adopted the provisions of ASC Topic 820 for fair value measurements of nonfinancial assets and nonfinancial liabilities that are recognized or disclosed at fair value in the financial statements on a nonrecurring basis. ASC Topic 820 establishes a fair value hierarchy that prioritizes the inputs to valuation techniques used to measure fair value. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to measurements involving significant unobservable inputs (Level 3 measurements). The three levels of the fair value hierarchy are as follows:
 
  —  Level 1 inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access at the measurement date.
 
  —  Level 2 inputs are inputs other than quoted prices included within Level 1 that are observable for the asset or liability, either directly or indirectly.
 
  —  Level 3 inputs are unobservable inputs for the asset or liability.
 
The level in the fair value hierarchy within which a fair value measurement in its entirety falls is based on the lowest level input that is significant to the fair value measurement in its entirety.
 
In 2009 and 2010, upon the adoption of ASC Topic 815-40, Derivatives and Hedging-Contracts in Entity’s Own Equity, certain financial instruments did fall within the requirements of ASC Topic 820 and are included in the disclosure below.
 
The Company has utilized an option pricing valuation model to determine the fair value of its outstanding common and convertible preferred stock warrant liabilities. The inputs to the model include fair value of the stock related to the warrant, exercise price of the warrant, expected term, expected volatility, risk-free interest rate and dividend yield. As several significant inputs are not observable, the overall fair value measurement of the warrants is classified as Level 3.


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
The following tables summarize the Company’s common and convertible preferred stock warrant liabilities measured at fair value on a recurring basis as of December 31, 2008, August 31, 2009, August 31, 2010 and February 28, 2011 (unaudited).
 
As of December 31, 2008, the fair value of the Company’s convertible preferred stock warrant liabilities were as follows:
 
                                 
        Fair value measurements
        at reporting date using
        Quoted prices
       
        in active
  Significant
  Significant
    Total fair
  markets for
  other
  other
    value as of
  identical
  observable
  unobservable
    December 31,
  assets
  inputs
  inputs
    2008   (Level 1)   (Level 2)   (Level 3)
 
Convertible preferred stock warrants
  $ 13     $     $     $ 13  
 
As of August 31, 2009, the fair value of the Company’s common and convertible preferred stock warrant liabilities were as follows:
 
                                 
          Fair value measurements
 
          at reporting date using  
          Quoted prices
             
          in active
    Significant
    Significant
 
    Total fair
    markets for
    other
    other
 
    value as of
    identical
    observable
    unobservable
 
    August 31,
    assets
    inputs
    inputs
 
    2009     (Level 1)     (Level 2)     (Level 3)  
 
Common stock warrants
  $ 2,931     $     $     $ 2,931  
Convertible preferred stock warrants
    13                   13  
                                 
Total
  $ 2,944     $     $     $ 2,944  
                                 


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
As of August 31, 2010, the fair value of the Company’s common and convertible preferred stock warrant liabilities were as follows:
 
                                 
          Fair value measurements
 
          at reporting date using  
          Quoted prices
             
          in active
    Significant
    Significant
 
    Total fair
    markets for
    other
    other
 
    value as of
    identical
    observable
    unobservable
 
    August 31,
    assets
    inputs
    inputs
 
    2010     (Level 1)     (Level 2)     (Level 3)  
 
Common stock warrants
  $ 8,578     $     $     $ 8,578  
Convertible preferred stock warrants
    333                   333  
                                 
Total
  $ 8,911     $     $     $ 8,911  
                                 
 
As of February 28, 2011 (unaudited), the fair value of the Company’s common and convertible preferred stock warrant liabilities were as follows:
 
                                 
          Fair value measurements
 
          at reporting date using  
          Quoted prices
             
          in active
    Significant
    Significant
 
    Total fair
    markets for
    other
    other
 
    value as of
    identical
    observable
    unobservable
 
    February 28,
    assets
    inputs
    inputs
 
    2011     (Level 1)     (Level 2)     (Level 3)  
 
Common stock warrants
  $ 8,666     $     $     $ 8,666  
Convertible preferred stock warrants
    331                   331  
                                 
Total
  $ 8,997     $     $     $ 8,997  
                                 


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
Prior to December 31, 2008, the changes in fair value of the Company’s Level 3 warrant liabilities were not significant. The changes in fair value of the Company’s Level 3 warrants from December 31, 2008 through February 28, 2011 were as follows:
 
                 
    Common
    Preferred
 
    Stock
    Stock
 
    Warrant
    Warrant
 
    Liabilities     Liabilities  
 
Fair value, December 31, 2008
  $     $ 13  
Cumulative effect of change in accounting principle
    3,092        
                 
Fair value, Adjusted balance January 1, 2009
    3,092       13  
Fair value adjustment of warrants
    (161 )      
                 
Fair value, August 31, 2009
    2,931       13  
Fair value adjustment of warrants
    70       81  
Issuance of warrants
    5,577       239  
                 
Fair value, August 31, 2010
    8,578       333  
Fair value adjustment of warrants (unaudited)
    88       (2 )
                 
Fair value, February 28, 2011 (unaudited)
  $ 8,666     $ 331  
                 
 
(l)   Accounts Receivable
 
Accounts receivable represents amounts owed to the Company from product sales and collaborative research and government grants. The Company had no amounts reserved for doubtful accounts at December 31, 2008, August 31, 2009, August 31, 2010 and February 28, 2011 (unaudited), as the Company expected full collection of the accounts receivable balances.
 
Customers representing greater than 10% of accounts receivable were as follows (in percentages):
 
                                   
    As of
  As of
  As of
    December 31,
  August 31,   February 28,
Customers
  2008   2009   2010   2011
                (Unaudited)
 
Customer A
    *       *       *       14.8    
Customer B
    *       *       *       19.5    
Customer C
    *       *       31.4       26.1    
Customer D
    *       65.0       27.2       21.7    
Customer E
    *       13.1       *       *    
Customer H
    95.6       16.9       37.4       *    
Customer I
    *       *       *       11.5    
 
 *  Less than 10%


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
 
Customers representing greater than 10% of revenues were as follows (in percentages):
 
                                                 
            Eight Months
           
    Year Ended
  Ended
  Year Ended
  Six Months Ended
    December 31,   August 31,
  August 31,
  February 28,
Customers
  2007   2008   2009   2010   2010   2011
                    (Unaudited)
 
Customer A
    *       *       *       12.7       11.0       19.0  
Customer B
    *       *       *       13.5       19.0       15.2  
Customer C
    *       *       *       9.8       *       19.5  
Customer D
    *       25.4       48.1       28.5       36.0       27.3  
Customer E
    *       43.5       27.6       *       *       *  
Customer F
    *       20.3       *       *       *       *  
Customer G
    88.4       *       *       *       *       *  
 
Less than 10%
 
(m)   Property and Equipment
 
Property and equipment is stated at cost. Depreciation is provided using the straight-line method over the shorter of the estimated useful lives or the remaining life of the lease. Depreciation periods for the Company’s property and equipment are as follows:
 
     
Automobiles and trucks
  3-5 years
Office, laboratory, farm and warehouse equipment and furniture
  3-5 years
Leasehold improvements
  3-10 years
Buildings
  14-39 years
 
(n)   Common and Convertible Preferred Stock Warrant Liabilities
 
Effective January 1, 2009, the Company adopted the guidance in ASC Topic 815-40 Derivatives and Hedging — Contracts in Entity’s Own Equity. In connection with the adoption, the Company determined that common stock warrants issued to the holders of Series F Convertible Preferred Stock were not considered indexed to the Company’s common stock and therefore require liability classification. On January 1, 2009, the Company recorded warrant liabilities of $3,092 and recorded a cumulative effect of change in accounting principle of $397 as a reduction of accumulated deficit representing the decline in fair value between the warrant issuance date and the adoption date.
 
The Company accounts for its warrants to purchase shares of the Company’s convertible preferred stock that are contingently redeemable as liabilities at fair value on the consolidated balance sheets.
 
These common and convertible preferred stock warrants are subject to re-measurement at each balance sheet date and the changes in fair value, if any, are recognized as other income (expense) until they expire or are exercised.
 
(o)   Convertible Preferred Stock
 
In connection with the Company’s decision to file a registration statement with the Securities Exchange Commission for an initial public offering of the Company’s common stock, the Company


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
adopted the provisions of ASC Topic 480-10-S99-3A, Classification and Measurement of Redeemable Securities.
 
The convertible preferred stock is not redeemable by the Company or at the option of the preferred stockholders. The holders of the Company’s outstanding convertible preferred stock, voting or consenting together as a separate class, control the vote of the Company’s stockholders. As a result, the holders of all series of the Company’s convertible preferred stock can vote to approve a change in control under circumstances that would trigger a deemed liquidation under the Company’s certificate of incorporation. As redemption of the convertible preferred stock through a deemed liquidation is outside the control of the Company, all shares of convertible preferred stock, previously classified in stockholders’ (deficit) equity, have been classified as temporary equity rather than as a component of stockholders’ (deficit) equity in the Company’s consolidated balance sheets for all periods presented. All series of convertible preferred stock are collectively referred to in the consolidated financial statements as convertible preferred stock.
 
The carrying value of convertible preferred stock was recorded at its fair value at the date of issue. The convertible preferred stock is not currently redeemable as the contingency (sale or merger of the Company) has not been met and is not probable. Subsequent adjustment will be made when it is probable that the security will become redeemable. There was no impact of adopting this accounting principle on the consolidated statements of operations or cash flows for all periods presented.
 
(p)   Stock-Based Compensation
 
The Company accounts for stock-based compensation arrangements with employees using a fair value method which requires the recognition of compensation expense for costs related to all stock-based payments including stock options. The fair value method requires the Company to estimate the fair value of stock-based payment awards on the date of grant using an option pricing model. The Company uses an option pricing model to estimate the fair value of options granted that are expensed on a straight-line basis over the vesting period. The Company accounts for stock options issued to non-employees based on the estimated fair value of the awards using the option pricing model. The measurement of stock-based compensation to non-employees is subject to periodic adjustments as the underlying equity instruments vest, and the resulting change in value, if any, is recognized in the Company’s consolidated statements of operations during the period the related services are rendered.
 
(q)   Revenue Recognition
 
Revenues are recognized when the following criteria are met: (1) persuasive evidence of an arrangement exists; (2) transfer of product or technology has been completed or services have been rendered; (3) the fee is fixed or determinable; and (4) collectability is reasonably assured. To date, the Company’s primary source of revenues is derived from collaborative research agreements and government grants.
 
Product Sales
 
Product sales are derived from sales of seeds. Product sales are recognized, net of discounts and allowances, once passage of title and risk of loss have occurred and contractually specified acceptance criteria have been met, provided all other revenue recognition criteria have also been met. Shipping and handling costs charged to customers are recorded as revenues and included in cost of product sales. To date, product sales have not been significant.


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
 
Collaborative Research and Government Grants
 
From time to time, the Company enters into research and development collaboration agreements with third parties including several biofuel producers and government agencies such as the Department of Energy (“DOE”) and the United States Department of Agriculture (“USDA”). The research and development collaboration agreements typically provide the Company with multiple revenue streams, which may include up-front, non-refundable fees for licensing certain of the Company’s technologies, government grants and fees for research and development activities, and contingent milestone payments based upon achievement of contractual criteria.
 
  •  Technology License Fees — For collaboration agreements in which the Company has continuing involvement, license fees are recognized on a straight-line basis over the term of the arrangement. Licensing fees are non-refundable and not subject to future performance.
 
  •  Government Grants — The Company receives payments from government entities in the form of government grants. Government grants generally provide the Company with partial cost reimbursement for certain types of expenditures in return for research and development activities over a contractually defined period. Revenues from government grants are recognized in the period during which the related costs are incurred, provided that the conditions under which the government grants were provided have been met and the Company has only perfunctory obligations outstanding.
 
  •  Research and Development Fees — Generally, fees for research and development activities are recognized as the services are performed over the performance period, as specified in the respective agreements. Certain of the Company’s collaboration agreements require the Company to deliver research data by specific dates and that the collective program plan will result in reaching specific crop characteristics by certain dates. For such arrangements, the Company recognizes revenues based on the approximate percentage of completion of services under the agreement, but the revenue recognized cannot exceed payments received by the Company to date under the agreement. The research and development period is estimated at the inception of each agreement and is periodically evaluated.
 
  •  Milestone Fees — Fees that are contingent based on achievement of substantive performance milestones at inception of the agreement are recognized based on the achievement of the milestone, as defined in the respective agreements.
 
Deferred Revenue
 
The Company recognizes deferred revenue to the extent that cash received under the collaboration agreement is in excess of the revenues recognized related to the agreement since the work under the agreement has not yet been performed at the time of cash receipt.
 
In April 2002, the Company entered into a multi-year discovery and development collaboration with Monsanto Company, focused on applying genomics technologies to identify genes that provide improvements in corn, soybean and certain other row crops. Pursuant to this agreement, Monsanto licensed rights to a portion of the Company’s trait discovery pipeline in certain row crops in exchange for license payments over several years. Monsanto also funded a research program with the Company. Payments for such licenses were nonrefundable and were not subject to future performance. During 2007 the Company recognized $3,500 and $2,846 for license and milestone fees, respectively, under the Monsanto agreement. The Company had no milestone fees for any other periods presented herein. In 2010, the Company and Monsanto agreed to amend the agreement. The


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
amendment included an additional license fee of $450 pertaining to an expansion of the license grant. This amount was recorded in revenues for collaborative research and government grants in 2010. In connection with the collaboration agreement, Monsanto also purchased 3,333,333 shares of our Series E Preferred Stock.
 
On December 20, 2007, the Company and a major consumer products company entered into a development and license agreement under which the Company is working to improve yields of a food product. The agreement provided that we would receive $7,500 in payments from this company over a five-year period provided milestones were met. In addition, the agreement provided that we would be entitled to receive a royalty based on the gross sales of crop varieties created under the agreement. The Company recognized revenue of $0, $1,000, $1,166, and $1,883, under this agreement in 2007, 2008, 2009, and 2010, respectively. Revenue recognized under this agreement for the six months ended February 28, 2010 and 2011 (unaudited), was $908, and $908, respectively.
 
The Company earns research funding revenues from several agreements with the DOE, the USDA, and several leading bio-fuels producers whereby the Company performs research activities and receives revenues that partially reimburse its expenses incurred. Under such grants and agreements, the Company retains a proprietary interest in the products and technology it develops. These expense reimbursements primarily consist of direct expense sharing arrangements. The Company recorded revenue related to these grants of approximately $800, $2,000, $900, and $2,800 in 2007, 2008, 2009, and 2010, respectively, and $1,431 and $1,492 for the six months ended February 28, 2010 and 2011, respectively (unaudited). The cumulative remaining amount to be claimed through September 2012 for all grants outstanding as of February 28, 2011 (unaudited) is approximately $5,715.
 
On December 16, 2008, the Company and a major agro-chemical company entered into a software license and collaboration agreement pursuant to which the Company provides software, software development and customer support for certain research application-based software. The agreement was structured into three phases and under the agreement, the Company is entitled to receive $1,500 in payments over an approximate 4.5 year period. The software delivered is comprised of multiple elements, which include software, installation, training, customization of software, and software support. Software support is considered post-contract customer support, or PCS. The Company does not have vendor specific objective evidence of fair value for its PCS. Accordingly, the Company recognizes revenues equal to the amount of expense recognized as services are rendered until the date that the PCS is the only undelivered element. Beginning on such date, the unrecognized revenue under the agreement will be recognized over the remaining PCS period. The Company recognized revenue and an equal amount of costs totaling $0, $180 and $268 under this agreement in 2008, 2009 and 2010, respectively. Revenue and related costs recognized for the six months ended February 28, 2010 and 2011 (unaudited) were $134 and $175, respectively.
 
(r)   Research and Development
 
Research and development expenses principally consist of personnel costs related to the Company’s research and development staff as well as depreciation of research and development assets. Research and development expenses also include costs incurred for laboratory supplies, reimbursable costs associated with government grants and collaborative agreements, third-party contract payments, consultants, facility and related overhead costs.


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
 
(s)   Seed Inventory
 
Seed inventory costs are computed on a first-in, first-out basis and valued at the lower of cost or market with any excess cost recognized during the period within cost of product sales. Due to the early stage of commercialization of the Company’s seed products and with no established market for these products, a full valuation reserve has been recorded against seed inventory for all periods presented.
 
(t)   Income Taxes
 
Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date.
 
Beginning with the adoption of FASB Interpretation No. 48, Accounting for Uncertainty in Income Taxes, included in FASB ASC Subtopic 740-10 — Income Taxes — Overall, as of January 1, 2009, the Company recognizes the effect of income tax positions only if those positions are more likely than not of being sustained. Recognized income tax positions are measured at the largest amount that is greater than 50% likely of being realized. Changes in recognition or measurement are reflected in the period in which the change in judgment occurs. Prior to the adoption of Interpretation 48, the Company recognized the effect of income tax positions only if such positions were probable of being sustained. Effective upon adoption of ASC 740, the Company recognizes interest and penalties accrued related to unrecognized tax benefits and penalties within its provision for income taxes. The Company had no such interest and penalties accrued at August 31, 2009 and August 31, 2010 and February 28, 2011 (unaudited).
 
For all periods presented the Company had no material unrecognized tax benefits or expenses that, if recognized, would affect the Company’s effective income tax rate in future periods. The Company is currently unaware of any issues under review that could result in significant payments, accruals, of material deviations from its recognized tax positions.
 
The major jurisdictions in which the Company files income tax returns include the United States federal jurisdiction as well as a state jurisdiction within the United States. All tax years from 1997 to present are subject to examination by the United States federal jurisdiction and by a state tax authority.
 
(u)   Comprehensive Income (Loss)
 
Comprehensive loss for all periods presented is the same as net loss as the results of the Company’s Brazilian operations were not significant.
 
(v)   Impairment of Long-Lived Assets
 
Long-lived assets, such as property and equipment, are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. The Company’s long-lived assets comprise a single asset group for evaluation purposes. The Company evaluates whether an impairment indicator occurs primarily based on progress achieved


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CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
against the Company’s business plans. To the extent that an impairment indicator has occurred, recoverability of assets to be held and used is measured by a comparison of the carrying amount of an asset to estimated undiscounted future cash flows expected to be generated by the asset. If the carrying amount of an asset exceeds its estimated undiscounted future cash flows, an impairment charge is recognized in the amount by which the carrying amount of the asset exceeds the fair value of the asset. For all periods presented herein, no impairment indicators have occurred and therefore no impairment charges have been recognized.
 
(w)   Basic and Diluted Net Loss Per Share
 
The Company’s Certificate of Incorporation provides that dividends in amounts specified in the Company’s Certificate of Incorporation must be paid to holders of the Company’s convertible preferred stock prior to and in preference of any declaration or payment of any cash dividend to common stockholders.
 
Because the holders of the Company’s convertible preferred stock are entitled to participate in dividends and earnings of the Company, the Company applies the two-class method in calculating its earnings per share for periods when the Company generates net income. The two-class method requires net income to be allocated between the common and convertible preferred stockholders based on their respective rights to receive dividends, whether or not declared. Because the convertible preferred stock is not contractually obligated to share in the Company’s losses, no such allocation was made for any period presented given the Company’s net losses.
 
Basic net loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of common shares outstanding. Diluted loss per common share is computed by dividing net loss available to common stockholders by the weighted average number of common shares and dilutive potential common share equivalents then outstanding, to the extent they are dilutive. Potential common shares consist of shares issuable upon the exercise of stock options and warrants (using the treasury stock method), and the weighted average conversion of the convertible preferred stock into shares of common stock (using the if-converted method). Dilutive loss per share is the same as basic loss per share for all periods presented because the effects of potentially dilutive items were anti-dilutive.
 
The following sets forth the computation of basic and diluted net loss per common share:
 
                                                 
    Year Ended
    Eight Months Ended
    Year Ended
    Six Months Ended
 
    December 31,     August 31,
    August 31,
    February 28,  
    2007     2008     2009     2010     2010     2011  
                            (Unaudited)  
 
Basic and diluted net loss per common share:
                                               
Net loss attributable to common stockholders
  $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
Less minimum dividend available to preferred stockholders
                                   
                                                 
Net loss attributable to common stockholders
  $ (20,455 )   $ (26,777 )   $ (18,696 )   $ (22,583 )   $ (11,723 )   $ (11,281 )
                                                 
Basic and diluted net loss per common share
  $ (3.84 )   $ (4.89 )   $ (3.33 )   $ (3.90 )   $ (2.04 )   $ (1.91 )
                                                 
Weighted average outstanding common shares used for net loss attributable to common stockholders:
                                               
Basic and diluted
    5,323,259       5,473,090       5,621,671       5,791,443       5,751,539       5,900,947  


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
The following potentially dilutive, common share equivalents were excluded from the calculation of diluted net loss per common share because their effect was antidilutive for each of the periods presented:
 
                                                 
                Eight Months
                   
    Year Ended
    Ended
    Year Ended
    Six Months Ended
 
    December 31,     August 31,
    August 31,
    February 28,  
    2007     2008     2009     2010     2010     2011  
                            (Unaudited)  
 
Options to purchase common stock
    6,192,124       6,714,652       6,396,700       6,874,588       6,549,200       7,192,391  
Warrants to purchase common stock
    2,707,697       2,907,697       2,907,697       5,984,620       2,907,697       5,984,620  
Warrants to purchase convertible preferred stock
    18,461       18,461       18,461       61,537       18,461       61,537  
Convertible preferred stock
    42,982,896       42,982,896       42,982,896       46,059,819       42,982,896       46,059,819  
                                                 
Total
    51,901,178       52,623,706       52,305,754       58,980,564       52,458,254       59,298,367  
                                                 
 
(x)   Segment and geographic information
 
Management has determined that it has one business activity and operates in one segment as it only reports financial information on an aggregate and consolidated basis to its Chief Executive Officer, who is the Company’s chief operating decision maker. Geographic information regarding the Company’s operations outside of North America is not significant for any periods presented.
 
(y)   Use of Estimates
 
The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions. This affects the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses during the reporting period. Significant items subject to such estimates and assumptions include the valuation of property and equipment, inventory, deferred tax assets, common stock, convertible preferred stock, stock options, and warrant liabilities. Actual results could differ from those estimates.
 
(z)   Recent Accounting Pronouncements
 
In October 2009, the FASB issued Accounting Standards Update (ASU), No. 2009-13, Revenue Recognition (Topic 605): Multiple Deliverable Revenue Arrangements. ASU No. 2009-13 addresses how to determine whether an arrangement involving multiple deliverables contains more than one unit of accounting and how to allocate consideration to each unit of accounting in the arrangement. This ASU replaces all references to fair value as the measurement criteria with the term selling price and establishes a hierarchy for determining the selling price of a deliverable. ASU 2009-13 also eliminates the use of the residual value method for determining the allocation of arrangement consideration. This standard was adopted by the Company on September 1, 2010 and the adoption of this standard did not have a material impact on its consolidated financial statements.
 
Effective September 1, 2010, the Company adopted ASU No. 2010-06, Fair Value Measurements and Disclosures, which requires previous fair value hierarchy disclosures to be further disaggregated by class of assets and liabilities. A class is often a subset of assets or liabilities within a line item in the balance sheet. In addition, significant reclassifications between Levels 1 and 2 of the fair value hierarchy are required to be disclosed. These additional requirements became effective September 1, 2011 for quarterly and annual reporting. The adoption did not have any impact on the Company’s consolidated financial statements. In addition, ASU 2010-06 requires more detailed disclosures


F-18


Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
regarding changes in Level 3 instruments. This disclosure change will be effective September 1, 2012 and is not expected to have an impact on the Company’s consolidated financial statements.
 
In April 2010, the FASB issued an ASU No. 2010-17, Revenue Recognition — Milestone Method (Topic 605): Milestone Method of Revenue Recognition. The standard provides guidance on defining a milestone and determining when it may be appropriate to apply the milestone method of revenue recognition for research or development transactions. Research or development arrangements frequently include payment provisions whereby a portion or all of the consideration is contingent upon milestone events such as successful completion of phases in a study or achieving a specific result from the research or development efforts. The amendments in these standards provide guidance on the criteria that should be met for determining whether the milestone method of revenue recognition is appropriate. The standard is effective for fiscal years and interim periods within those years beginning on or after June 15, 2010, with early adoption permitted, and applies to milestones achieved on or after that time. This standard was adopted by the Company on September 1, 2010 and the adoption of this standard did not have a material impact on its consolidated financial statements.
 
(2)   Investments Held to Maturity
 
The Company held investments in marketable debt securities that were classified as held to maturity as follows:
 
                                 
    As of
    As of
       
    December 31,
    August 31,     As of
 
    2008     2009     2010     February 28, 2011  
                      (Unaudited)  
 
Restricted certificates of deposit
  $ 200     $ 100     $     $  
U.S Treasury and federal agency securities
    33,086       15,384              
                                 
Total
  $ 33,286     $ 15,484     $     $  
                                 
 
The fair value of the securities was substantially the same as the carrying value.


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CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
(3)   Property and Equipment
 
Property and equipment are summarized as follows:
 
                                 
    As of
    As of
    As of
 
    December 31,
    August 31,     February 28,
 
    2008     2009     2010     2011  
                      (Unaudited)  
 
Land
  $     $     $ 43     $ 43  
Automobiles and trucks
    261       298       361       361  
Buildings
    2,044       2,435       3,391       3,391  
Office, laboratory, farm and warehouse equipment and furniture
    15,771       16,845       16,794       16,881  
Leasehold improvements
    5,637       5,719       5,719       5,751  
                                 
      23,713       25,297       26,308       26,427  
Less accumulated depreciation
    (14,866 )     (16,413 )     (17,856 )     (18,876 )
                                 
Property and equipment, net
  $ 8,847     $ 8,884     $ 8,452     $ 7,551  
                                 
 
(4)   Accounts Payable and Accrued Expenses
 
Accounts payable and accrued expenses consisted of the following:
 
                                 
    As of
    As of
    As of
 
    December 31,
    August 31,     February 28,
 
    2008     2009     2010     2011  
                      (Unaudited)  
 
Accounts payable
  $ 1,466     $ 920     $ 1,049     $ 871  
Accrued payroll and related expenses
    988       1,249       1,490       1,381  
Research and development contracts
    607       1,021       834       1,367  
Accrued grower commitments
          755       185       51  
Other
    91       127       216       254  
                                 
    $ 3,152     $ 4,072     $ 3,774     $ 3,924  
                                 


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
(5)   Long-Term Debt
 
Long-term debt is summarized as follows:
 
                                 
    As of
    As of
    As of
 
    December 31,
    August 31,     February 28,
 
    2008     2009     2010     2011  
                      (Unaudited)  
 
Equipment Loan
                               
Tranche 1 matures June, 2013, net of discount of $74,651
  $     $     $ 2,462     $ 2,025  
Tranche 2 matures August, 2013, net of discount of $99,537
                3,883       3,234  
                                 
                      6,345       5,259  
Other
    87       47       35       28  
                                 
      87       47       6,380       5,287  
Less current portion
    (71 )     (35 )     (2,182 )     (2,178 )
                                 
    $ 16     $ 12     $ 4,198     $ 3,109  
                                 
 
Equipment Loan
 
In January 2010, the Company entered into a Loan and Security Agreement (the Loan Agreement) with a commercial bank (the Bank). The Loan Agreement provides financing for qualified equipment purchases. The Company borrowed a total of $7,000 in two tranches at interest rates of Prime Rate plus 2.75% (6.0% as of February 28, 2011, unaudited), which is to be repaid over 36 to 40 months. In connection with the Loan Agreement, the Company issued the Bank warrants to purchase 43,076 shares of the Company’s Series F Convertible Preferred Stock at an exercise price of $6.50 per share. The fair value of the warrants at the inception of the Loan Agreement was $239. The fair value was recorded as a discount on the equipment loan and is being recognized over the term of the equipment loan as interest expense (see Note 7). At August 31, 2010 and February 28, 2011 (unaudited), the Company also held restricted cash of $3,000 in the form of a deposit related to the Loan Agreement.
 
The Loan Agreement is secured by certain of the Company’s assets, excluding intellectual property, and requires compliance with covenants that require certain reporting and maintenance of certain specified ratios. At February 28, 2011 (unaudited), the Company was in compliance with the Loan Agreement debt covenants.
 
Borrowing Agreement
 
In July 2004, the Company entered into a borrowing agreement (Borrowing Agreement) to finance the construction of a greenhouse located in the United States. The Company borrowed $4,000 at an interest rate of 7% from the Bank. Final payment on the borrowings was made on February 1, 2008. In conjunction with the borrowing agreement, the Company issued the Bank warrants to purchase 18,461 shares of the Company’s Series E Convertible Preferred Stock at an exercise price of $6.50 per share (see Note 7).


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
The aggregated maturities of debt as of February 28, 2011 (unaudited) are as follows:
 
         
February 28, 2011 (unaudited)
       
Remaining six months of fiscal year 2011
  $ 1,089  
2012
    2,175  
2013
    2,019  
2014
    4  
         
    $ 5,287  
         
 
(6)   Stock-Based Compensation
 
Stock Option and Stock Issuance Plans
 
The Company has established two stock option and stock issuance plans: the Ceres, Inc. 2000 Stock Option/Stock Issuance Plan, as restated and the Ceres, Inc. 2010 Stock Option/Stock Issuance Plan (collectively the “Option Plans”). The Option Plans provide for grants of Incentive Stock Options (“ISOs”) to employees and Nonstatutory Stock Options (“NSOs”) and restricted stock to employees, directors, and consultants. The option term, as determined by the Company’s Board of Directors, may not exceed ten years. Vesting, also determined by the Company’s Board of Directors, generally occurs ratably over four years. ISOs and NSOs may be granted at a price per share not less than the fair market value at the date of grant.
 
The Company has issued restricted stock awards under the Option Plans. Vesting of stock awards is determined at the discretion of the Board of Directors. As of August 31, 2010 and February 28, 2011 (unaudited), there were 5,000 unvested restricted stock awards outstanding.
 
The total number of shares reserved for issuance under the Option Plans is 11,765,000. As of August 31, 2010 and February 28, 2011 (unaudited), the Company had 1,148,257 and 744,454 shares available, respectively, under the Option Plans for future grant.
 
Stock Option Valuation and Compensation
 
The Company uses a Black Scholes option pricing model to determine the fair value of stock options. The weighted average grant date fair value of stock option awards was $1.32, $1.59, $1.57, and $1.51 per option share for 2007, 2008, 2009, and 2010, respectively, and $1.61 per option share for the six months ended February 28, 2011 (unaudited).
 
The determination of the fair value of stock option awards on the date of grant using an option-pricing model is affected by the Company’s common stock valuation as well as assumptions regarding a number of complex and subjective variables. The fair value of the Company’s common stock underlying the stock options has historically been determined by our Board of Directors with input from management. In the absence of a public trading market for our common stock, our Board has determined the fair value of the common stock utilizing methodologies, approaches and assumptions consistent with the American Institute of Certified Public Accountants Practice Guide, Valuation of Privately Held Company Equity Securities Issued as Compensation.
 
The weighted average grant date estimated fair value of the Company’s common stock was $2.11, $2.17, $2.16 and $2.32 per share for 2007, 2008, 2009 and 2010, respectively, and $2.17 and $2.49 for the six months ended February 28, 2010 and 2011 (unaudited), respectively.


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
The fair value of employee stock options was estimated using the following weighted-average assumptions:
 
                         
            Eight months
  Year
       
            ended
  ended
  Six Months Ended
    Year ended December 31,   August 31,
  August 31,
  February 28,
    2007   2008   2009   2010   2010   2011
                    (Unaudited)
 
Expected term (in years)
  6.25   6.25   6.25   6.25   6.25   6.25
Expected volatility
  85%   85%   85%   70%   70%   70%
Risk free interest rate
  3.41%-5.15%   1.92%-3.41%   2.10%-3.18%   2.29%-2.69%   2.56%-2.69%   1.48%-2.44%
Expected dividend yield
  0%   0%   0%   0%   0%   0%
 
Expected Term — Because of limited employee share option exercises, the Company uses a simplified method in which the expected term of an award is presumed to be mid-point between the vesting date and the expiration date of the award. The expected term for all employee option grants is 6.25 years.
 
Expected Volatility — The Company estimates the volatility of its common stock by using the historical volatility of a group of comparable companies over the option’s expected term. The decision to use historical volatility of comparable companies was based upon the fact that the Company’s stock is not actively traded.
 
Risk-Free Interest Rate — The Company bases the risk-free interest rate used in the option valuation model based on U.S. Treasury zero-coupon issues with remaining terms similar to the expected term on the options.
 
Expected Dividend Yield — The Company does not anticipate paying any cash dividends in the foreseeable future.
 
Stock-based compensation costs included in operating expenses and total intrinsic value of options exercised are as follows:
 
                                                 
            Eight months
  Year
       
    Year ended
  ended
  ended
  Six Months Ended
    December 31,   August 31,
  August 31,
  February 28,
   
2007
 
2008
  2009   2010  
2010
 
2011
                    (Unaudited)
 
Stock-based compensation costs included in operating expenses
  $ 727     $ 1,172     $ 1,082     $ 1,300     $ 612     $ 595  
Intrinsic value of stock options exercised
    97       402       194       298       187       177  


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
Stock Option Activity
 
The following summarizes the stock option transactions under the Option Plans during the periods presented:
 
                 
        Weighted
        Average
   
Shares
 
Exercise Price
 
Options outstanding at December 31, 2007
    6,192,124     $ 1.17  
Options granted
    996,000       2.25  
Options exercised
    (212,297 )     0.28  
Options forfeited
    (261,175 )     1.32  
                 
Options outstanding at December 31, 2008
    6,714,652     $ 1.35  
Options granted
    94,000       2.25  
Options exercised
    (105,500 )     0.32  
Options forfeited
    (306,452 )     1.61  
                 
Options outstanding at August 31, 2009
    6,396,700     $ 1.36  
Options granted
    972,000       2.25  
Options exercised
    (146,000 )     0.22  
Options forfeited
    (348,112 )     2.03  
                 
Options outstanding at August 31, 2010
    6,874,588     $ 1.48  
Options granted (unaudited)
    875,500       2.43  
Options exercised (unaudited)
    (86,000 )     0.40  
Options forfeited (unaudited)
    (471,697 )     1.31  
                 
Options outstanding at February 28, 2011(unaudited)
    7,192,391     $ 1.62  
                 
 
The following table summarizes information about stock options outstanding and exercisable at February 28, 2011 (unaudited):
 
                                                 
    Number
          Number
       
    Outstanding
  Average
      Exercisable
      Average
    as of
  Remaining
  Weighted-
  as of
  Weighted-
  Remaining
Range of
  February 28,
  Contractual
  Average
  February 28,
  Average
  Contractual
Exercise Price
 
2011
 
Life
 
Exercise Price
 
2011
 
Exercise Price
 
Life
 
$0.4
    3,000       0.01     $ 0.40       3,000     $ 0.40       0.01  
$0.60 to $0.65
    2,141,500       1.67       0.63       2,141,500       0.63       1.67  
$1.30 to $1.35
    1,286,083       5.05       1.30       1,283,083       1.30       5.05  
$2.25
    2,932,308       7.77       2.25       1,511,299       2.25       7.27  
$2.44
    829,500       9.81       2.44             2.44       9.81  
                                                 
      7,192,391                       4,938,882                  
                                                 
 
No tax benefits have been recorded on compensation costs recognized for options exercised. As of August 31, 2010, there was $2,059 of total unrecognized compensation cost related to stock options. That cost is expected to be recognized over a weighted average of 2.79 years. The Company’s policy is to issue new shares for options exercised.


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
(7)   Convertible Preferred Stock and Warrants
 
Convertible Preferred Stock
 
In September 2007, the Company raised $74,182 from various investors by issuing Series F Convertible Preferred Stock at $6.50 per share. In conjunction with the purchase of the Series F convertible preferred stock, a total of 2,307,697 warrants to purchase common stock at $6.50 per share were issued to the holders of Series F Convertible Preferred Stock.
 
In June 2010, the Company raised $20,000 from various investors by issuing Series G Convertible Preferred Stock at $6.50 per share. In conjunction with the purchase of the Series G convertible preferred stock, a total of 3,076,923 warrants to purchase common stock at $6.50 per share were issued to the holders of Series G Convertible Preferred Stock.
 
Holders of the convertible preferred stock are entitled to certain preferences over common stock and are entitled to receive, in preference to any dividend on the common stock, noncumulative dividends at the per annum per share rate as follows:
 
                                                                 
   
Series A
 
Series B
 
Series C
 
Series C-1
 
Series D
 
Series E
 
Series F
 
Series G
 
Liquidation preference per share
  $ 1.00     $ 2.00     $ 4.00     $ 4.00     $ 6.00     $ 6.50     $ 6.50     $ 6.50  
Noncumulative dividends per share
    0.10       0.20       0.40       0.40       0.60       0.65       0.65       0.65  
 
Such dividends are payable when, as and if declared by the Board of Directors. No dividends have been declared to date. Each share of convertible preferred stock is convertible at the holder’s option at any time into one share of common stock, subject to adjustments. All of the outstanding shares of convertible preferred stock will automatically convert to common stock on a one-for-one basis immediately upon the closing of an initial public offering of the common stock of the Company if the price per share of the offering is not less than $6.50 per share and with aggregate proceeds raised of not less than $40,000. The holders of the convertible preferred stock are entitled to the number of votes equal to the number of shares of common stock into which their preferred shares are convertible.
 
Liability Classified Common Stock Warrants
 
Warrants to purchase the following shares of common stock were outstanding as follows:
 
                                         
    Number of shares    
    As of
  As of
  As of
   
    December 31,
  August 31,   February 28,
  Exercise
Series
 
2008
 
2009
 
2010
 
2011
 
Price
                (Unaudited)    
 
F
    2,307,697       2,307,697       2,307,697       2,307,697     $ 6.50  
G
                3,076,923       3,076,923     $ 6.50  
 
Warrants issued in connection with Series F Convertible Preferred Stock
 
In connection with the issuance of the Series F Convertible Preferred Stock in September 2007, the Company issued 2,307,697 warrants to purchase common stock. The Company estimated the fair


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
value upon issuance of the warrants to be $3,489 based on a risk-free rate of 4.29%, volatility of 85%, expected term of 8 years and 0% dividend yield. The warrants are immediately exercisable and expire on the eighth anniversary of the issuance date or at the time of a merger, acquisition, or qualified underwritten public offering of the Company’s common stock.
 
As discussed in Note 1(n), effective January 1, 2009, the common stock warrants issued to the holders of Series F Convertible Preferred Stock and previously recorded as a component of additional paid-in capital, were reported as a liability at fair value as of January 1, 2009 and for each subsequent balance sheet date.
 
The fair value of these warrants was estimated using the following assumptions:
 
                                 
    As of
  As of
    August 31,   February 28,
   
2009
 
2010
 
2010
 
2011
            (Unaudited)
 
Expected term (in years)
    6.0       5.0       5.5       4.5  
Expected volatility
    90 %     90 %     90 %     90 %
Risk free interest rate
    3.21 %     1.47 %     2.36 %     2.13 %
Expected dividend yield
    0 %     0 %     0 %     0 %
Estimated fair value (in thousands)
  $ 2,931     $ 2,994     $ 2,995     $ 2,945  
 
Warrants issued in connection with Series G Convertible Preferred Stock
 
In connection with the issuance of the Series G Convertible Preferred Stock in June 2010, the Company issued 3,076,923 warrants to purchase common stock. The Company estimated the fair value upon issuance of the warrants to be $5,577 based on a risk-free rate of 3.72%, expected volatility of 85%, expected term of 10 years and 0% dividend yield.
 
The warrants are immediately exercisable and expire on the tenth anniversary of the issuance date or at the time of a merger, acquisition, or qualified underwritten public offering of the Company’s common stock.
 
The fair value of these warrants was estimated using the following assumptions:
 
                 
    As of
  As of
    August 31,
  February 28,
   
2010
 
2011
        (Unaudited)
 
Expected term (in years)
    9.8       9.3  
Expected volatility
    85 %     85 %
Risk free interest rate
    2.70 %     3.42 %
Expected dividend yield
    0 %     0 %
Estimated fair value (in thousands)
  $ 5,584     $ 5,721  


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
Liability Classified Convertible Preferred Stock Warrants
 
Warrants to purchase the following shares of convertible preferred stock were outstanding as follows:
 
                                         
    Number of shares    
    As of December 31,
  As of August 31,   As of February 28,
  Exercise
Series
 
2008
 
2009
 
2010
 
2011
 
Price
                (Unaudited)    
 
E
    18,461       18,461       18,461       18,461     $ 6.50  
F
                43,076       43,076     $ 6.50  
 
Warrants issued in connection with Borrowing and Loan Agreement
 
In July 2004, in conjunction with the Borrowing Agreement (see Note 5) the Company issued the Bank warrants to purchase 18,461 shares of the Company’s Series E Convertible Preferred Stock at a price of $6.50 per share expiring on the later of July 31, 2014 or five years subsequent to the closing of an initial public offering of the common stock of the Company. During 2010 the warrants were modified to extend the expiration date to the later of February 29, 2020 or five years subsequent to the closing of an initial public offering of the common stock of the Company. The incremental value of the modification was expensed during 2010.
 
In February 2010, in connection with the Loan Agreement (see Note 5), the Company issued the Bank warrants to purchase 43,076 shares of the Company’s Series F Convertible Preferred Stock at a price of $6.50 per share. The Company estimated the fair value of the warrants to be $239 based on a risk-free interest rate of 3.73%, volatility of 85%, expected term of 10 years and 0% dividend yield. The warrants expire the later of February 29, 2020 or five years subsequent to the closing of an initial public offering of the common stock of the Company.
 
The Company estimated the fair value of the Series E and F warrants to be $99 and $232, respectively, based on a risk-free interest rate of 3.42%, volatility of 85%, expected term of 9 years, and 0% dividend yield at February 28, 2011 (unaudited).
 
Equity Classified Common Stock Warrants
 
Warrants issued in connection with Noble Agreement
 
In May 2006, the Company entered into a collaboration agreement with The Samuel Roberts Noble Foundation, Inc. (“Noble Agreement”) to establish a research program (see Note 11). In connection with this collaboration, the Company granted Noble a warrant to purchase 400,000 shares of the Company’s common stock for an exercise price of $10.00 per share. The warrant vests in equal installments of 100,000 shares on May 19, 2009, May 19, 2011, May 19, 2013, and May 19, 2015, respectively, and shall remain exercisable for a period of two years from the respective vesting dates. This warrant is accounted for at fair value and remeasured until vested. The fair value, including the resulting change in value as a result of remeasurement is being recognized as research and development expense. The inception to date expense recognized with respect to this warrant totals $130 as of February 28, 2011 (unaudited). At February 28, 2011, 100,000 warrants had vested under this arrangement. The fair value of the warrants not yet vested at February 28, 2011 (unaudited) was $174 using a risk-free rate ranging from 0.69% to 2.48% based on the respective exercise periods of


F-27


Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
each installment, expected volatility of 70%, expected terms of 2.2 to 6.2 years based on the respective exercise periods of each installment, and 0% dividend yield.
 
Warrants issued in connection with TAMU Agreement
 
In August 2007, the Company entered into a sponsored research and intellectual property rights agreement with The Texas A&M University System (“TAMU”) (“TAMU Agreement”) to establish a research program. In connection with this collaboration, the Company granted TAMU a warrant to purchase 200,000 shares of the Company’s common stock for an exercise price of $10.00 per share. The warrant vests based on certain research and commercialization milestones being met and shall remain exercisable until August 28, 2017. This warrant is accounted for at fair value and remeasured until the vesting targets are met. The fair value, including the resulting change in value as a result of remeasurement is being recognized as research and development expense. The inception to date expense recognized with respect to this warrant totals $125 as of February 28, 2011 (unaudited). The fair value of the warrant at February 28, 2011(unaudited) was $198, using a risk-free rate of 2.82%, expected volatility of 70%, expected term of 6.5 years and 0% dividend yield. No warrants had vested under this arrangement as of February 28, 2011.
 
Shares of Common Stock Reserved for Future Issuance
 
At February 28, 2011 (unaudited), the Company had reserved shares of common stock for future issuance as follows:
 
         
Conversion of outstanding convertible preferred stock
    46,059,819  
Stock options outstanding
    7,192,391  
Stock options available for grant
    744,454  
Preferred stock warrants
    61,537  
Common stock warrants
    5,984,620  
         
      60,042,821  
         
 
(8)   Income Taxes
 
Deferred tax benefits associated with deferred tax assets are offset by a corresponding valuation allowance except to the extent of federal credits refundable in 2009. Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and amounts used for income tax purposes.
 
Income tax expense (benefit) attributable to income (loss) before income taxes consisted of the following:
 
                         
   
Current
   
Deferred
   
Total
 
 
Year ended December 31, 2007
                       
U.S. federal
  $ 7     $     $ 7  
State and local
                 
                         
    $ 7     $     $ 7  
                         
 


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
                         
   
Current
   
Deferred
   
Total
 
 
Year ended December 31, 2008
                       
U.S. federal
  $ (149 )   $     $ (149 )
State and local
    1             1  
                         
    $ (148 )   $     $ (148 )
                         
 
                         
 
 
Current
   
Deferred
   
Total
 
 
Eight Months ended August 31, 2009
                       
U.S. federal
  $ (115 )   $ (97 )   $ (212 )
State and local
    1             1  
                         
    $ (114 )   $ (97 )   $ (211 )
                         
 
                         
   
Current
   
Deferred
   
Total
 
 
Year ended August 31, 2010
                       
U.S. federal
  $     $ 64     $ 64  
State and local
    1             1  
                         
    $ 1     $ 64     $ 65  
                         
 
Income tax expense differs from the amount computed by applying the federal corporate income tax rate of 34% to the loss before income taxes due to the following:
 
                                 
                Eight Months
       
                Ended
    Year Ended
 
    Year Ended December 31     August 31,
    August 31
 
   
2007
   
2008
   
2009
   
2010
 
 
Computed “expected” tax expense (benefit)
  $ (6,953 )   $ (9,155 )   $ (6,428 )   $ (7,656 )
Increase (reduction) in income taxes resulting from:
                               
Stock-based compensation
    185       350       269       435  
State and local income taxes, net of federal income tax benefit
    1       1       1       1  
Domestic R&D Credits
    (661 )     (2,287 )     (162 )      
Other
    181       15       10       69  
Change in valuation allowance
    7,254       10,928       6,099       7,216  
                                 
Income tax expense (benefit)
  $ 7     $ (148 )   $ (211 )   $ 65  
                                 

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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
The following table summarizes the tax effects of temporary differences that give rise to significant portions of the deferred tax assets and liabilities at each period end:
 
                         
    As of
    As of
    As of
 
    December 31,
    August 31,
    August 31,
 
   
2008
   
2009
   
2010
 
 
Deferred tax assets:
                       
Accrued liabilities
  $ 212     $ 146     $ 384  
Other assets
    11       14       14  
Inventory capitalization
          67       59  
Deferred revenue
                270  
                         
Total current deferred tax assets
    223       227       727  
                         
Noncurrent assets:
                       
Depreciation
    1,202       1,482       1,480  
Inventory reserves
    973       1,674       1,451  
Deferred rent
    51       51       48  
Other assets
    70       72       153  
Net operating loss carryforward
    45,985       52,358       60,211  
Federal and state tax credit carryforward
    8,691       8,576       8,921  
                         
Total noncurrent deferred tax assets
    56,972       64,213       72,264  
                         
Total deferred tax assets
    57,195       64,440       72,991  
Less valuation allowance
    (57,195 )     (64,343 )     (72,991 )
                         
Net deferred tax assets
  $     $ 97     $  
                         
 
As of August 31, 2010, the Company has a net operating loss (“NOL”) carryforward for federal and state income tax purposes of approximately $154,205 and $133,364, respectively. The federal NOL is available to offset future taxable income, if any, and will expire from 2018 through 2030. The state NOL will expire from 2016 through 2032. The Company also has alternative minimum tax (“AMT”) for state income tax purposes of approximately $17 and research and development tax credit carryforwards for federal income tax purposes of approximately $8,910, which are available to offset future tax liabilities, if any, through 2028.
 
In accordance with Internal Revenue Code (IRC) Sections 382 and 383, the annual utilization of net operating loss carryforwards and credits is limited if a change in control occurs, including a change resulting from an initial public offering. The Company has not completed a Section 382 analysis to determine if a change in ownership has occurred. Until such analysis is completed, there are no assurances that the existing net operating loss carryforwards or credits are not subject to significant limitation.
 
In assessing the realizability of deferred tax assets, management considers whether it is more likely than not that some portion or all of the deferred tax assets will not be realized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the periods in which those temporary differences become deductible. Management considers the scheduled reversal of deferred tax liabilities, projected future taxable income, and tax planning strategies in making this assessment. Based upon the historical taxable income (loss) and projections for future taxable income (loss) over the periods in which the deferred tax assets are deductible, management believes it is more likely that the Company will not realize the benefits of these


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Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
deductible differences. Accordingly, full valuation allowances have been provided except to the extent of federal credits refundable in 2009.
 
(9)   401(k) Benefit Plan
 
The Company has a 401(k) profit sharing plan (the “Plan”) which covers substantially all employees of the Company. Plan participants may make voluntary contributions up to 60% of their earnings up to the statutory limitation. The Company will match 50% of each employee contribution up to a maximum of 4% of the employee’s salary in matching funds per pay period. The matching contribution vests over a three-year service period; 25% vests immediately and an additional 25% vests for each year of service to the Company thereafter over the next three years. The Company recorded expense of $164, $218, $222, $287, $139 and $131 in 2007, 2008, 2009, 2010, and for the six months ended February 28, 2010 and February 28, 2011(unaudited), respectively. The Company made no discretionary contributions in any year.
 
(10)   Commitments and Contingencies
 
The Company leases certain of its facilities and equipment under various noncancelable operating leases expiring through 2023. The lease on the facilities contains provisions for future rent increases. The Company records monthly rent expense equal to the total of the payments due over the lease term, divided by the number of months of the lease term. The difference between rent expense recorded and the amount paid is credited or charged to deferred rent, which is reflected as a separate line item in the accompanying consolidated balance sheets as of December 31, 2008, August 31, 2009, August 31, 2010 and February 28, 2011 (unaudited).
 
In connection with one of its facilities leases, the Company received a reimbursement for leasehold improvements of $270. This reimbursement is a lease incentive which has been recognized as a liability in deferred rent and is being amortized to rent expense on a straight-line basis over the lease term. Total rental expense recognized during each period was $522, $460, $303, $460, $227 and $241 for 2007, 2008, 2009, 2010, and the six months ended February 28, 2010 and February 28, 2011 (unaudited), respectively.
 
Future minimum payments under noncancelable operating leases as of February 28, 2011 (unaudited) are as follows:
 
         
    Operating
 
   
leases
 
 
February 28, 2011
       
Remaining six months of fiscal year 2011
  $ 466  
2012
    824  
2013
    620  
2014
    368  
2015 and beyond
    115  
         
Total minimum lease payments
  $ 2,393  
         
 
(11)   Research Collaboration Agreements
 
The Company has a number of research agreements with academic collaborators, including among others, Texas A&M University, The Samuel Roberts Noble Foundation, Inc. (“Noble”), and the


F-31


Table of Contents

CERES, INC.

Notes to Consolidated Financial Statements — (Continued)
(Information for the six months ended February 28, 2010 and 2011 is unaudited)
(In thousands, except share and per share data)
 
Institute of Crop Sciences of the Chinese Academy of Agricultural Sciences. In conjunction with these agreements, the Company receives certain exclusive options or licensing rights to technology and intellectual property developed under these agreements. The Company expenses the services received under these agreements to research and development in the period in which the services are rendered. The Company also licenses technology from third parties. Initial payments under these license agreements are expensed on a straight-line basis over the license term.
 
Noble Agreement
 
In May 2006, the Company entered into a collaboration agreement with Noble to establish a research program. Under the Noble Agreement, the Company agreed to fund certain research activities undertaken by Noble in an amount up to $3,800 through 2012 and granted Noble a warrant to purchase 400,000 shares of the Company’s common stock for an exercise price of $10.00 per share (see Note 7). Additional projects may be added under the agreement, if agreed to by both parties.
 
TAMU Agreement
 
In August 2007, the Company entered into a sponsored research and intellectual property rights agreement with Texas A&M University to establish a research program. Under the agreement, the Company agreed to fund certain research activities undertaken by TAMU in an amount up to $5,100 through 2012 and granted TAMU a warrant to purchase 200,000 shares of the Company’s common stock for an exercise price of $10.00 per share (see Note 7).
 
At February 28, 2011 (unaudited), the future minimum payments under the Company’s research collaboration agreements are as follows:
 
         
February 28, 2011
       
Remaining six months of fiscal year 2011
  $ 1,271  
2012
    1,984  
2013
    251  
2014 and beyond
    44  
         
    $ 3,550  
         
 
(12)   Subsequent Events
 
In connection with the issuance of the consolidated financial statements for the year ended August 31, 2010, the Company evaluated subsequent events through February 4, 2011, the date the consolidated financial statements were available to be issued, and determined that there are no subsequent events that require disclosure.
 
In connection with the reissuance of the consolidated financial statements for the year ended August 31, 2010 and the interim consolidated financial statements for the six months ended February 28, 2011, the Company has evaluated subsequent events through May 19, 2011, the date the consolidated financial statements were reissued.
 
On May 8, 2011, the Board of Directors of the Company approved the filing of a registration statement with the Securities and Exchange Commission for an initial public offering of the Company’s common stock (unaudited).


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Table of Contents

 
          Shares
Ceres, Inc.
Common Stock
 
 
(CERES LOGO)
 
 
Goldman, Sachs & Co.
 
Barclays Capital
 
 
Through and including          , 2011 (the 25th day after the date of this prospectus), all dealers effecting transactions in these securities, whether or not participating in this offering, may be required to deliver a prospectus. This is in addition to a dealer’s obligation to deliver a prospectus when acting as an underwriter and with respect to an unsold allotment or subscription.
 


Table of Contents

 
PART II
 
INFORMATION NOT REQUIRED IN PROSPECTUS
 
Item 13.   Other Expenses of Issuance and Distribution
 
The actual and estimated expenses in connection with this offering are as follows:
 
         
SEC Registration Fee
  $ 11,610  
Printing and Engraving Expense
    *
Legal Fees
    *
Accounting Fees
    *
Nasdaq Listing Fee
    *
Financial Industry Regulatory Authority, Inc. Filing Fee
    10,500  
Transfer Agent Fee
    *
Miscellaneous Expenses
    *
         
Total
  $ *
 
 
* To be filed by amendment.
 
Item 14.   Indemnification of Directors and Officers
 
Section 102(b)(7) of the Delaware General Corporation Law, or DGCL, provides that a corporation may, in its original certificate of incorporation or an amendment thereto, eliminate or limit the personal liability of a director for violations of the director’s fiduciary duty, except (1) for any breach of the director’s duty of loyalty to the corporation or its stockholders, (2) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (3) pursuant to Section 174 of the DGCL, which provides for liability of directors for unlawful payments of dividends or unlawful stock purchases or redemptions or (4) for any transaction from which a director derived an improper personal benefit.
 
Section 145 of the DGCL provides that a corporation may indemnify any person, including an officer or director, who is, or is threatened to be made, party to any threatened, pending or completed legal action, suit or proceeding, whether civil, criminal, administrative or investigative, other than an action by or in the right of such corporation, by reason of the fact that such person was an officer, director, employee or agent of such corporation or is or was serving at the request of such corporation as an officer, director, employee or agent of another corporation or enterprise. The indemnity may include expenses (including attorneys’ fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in connection with such action, suit or proceeding, provided such officer, director, employee or agent acted in good faith and in a manner he reasonably believed to be in, or not opposed to, the corporation’s best interest and, for criminal proceedings, had no reasonable cause to believe that his conduct was unlawful. A Delaware corporation may indemnify any officer or director in an action by or in the right of the corporation under the same conditions, except that no indemnification is permitted without judicial approval if the officer or director is adjudged to be liable to the corporation. Where an officer or director is successful on the merits or otherwise in the defense of any action referred to above, the corporation must indemnify him against the expenses that such officer or director actually and reasonably incurred.
 
Our bylaws provide for indemnification of the officers and directors to the full extent permitted by the DGCL.
 
The proposed form of Underwriting Agreement to be filed as Exhibit 1.1 to this registration statement provides for indemnification by the underwriters of the registrant and its directors and certain officers for certain liabilities arising under the Securities Act.


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Item 15.   Recent Sale of Unregistered Securities
 
Since April 1, 2008, we have issued the following securities that were not registered under the Securities Act:
 
(1) In August 2009, we sold an aggregate of 3,076,923 shares of Series G convertible preferred stock at a per share purchase price of $6.50 pursuant to a stock purchase agreement. Purchasers of the Series G convertible preferred stock also received, for each share purchased, a warrant to purchase one share of our common stock at an exercise price of $6.50 per share.
 
(2) Since April 1, 2008, we have granted options to employees and directors to purchase an aggregate of 2,915,000 shares of our common stock under our equity incentive plans at exercise prices ranging from $2.25 to $2.44. During this period, options to purchase 529,797 shares of our common stock were exercised with an average per share exercise price of $0.29 for cash consideration to us in the aggregate amount of $153,641.13.
 
The issuances of preferred stock and warrants described in item (1) above were deemed exempt from registration under Section 4(2) or Regulation D of the Securities Act. The issuances of options and shares in item (2) above was deemed exempt from registration in reliance on Rule 701 promulgated under the Securities Act as transactions pursuant to compensatory benefit plans and contracts relating to compensation. All of the foregoing securities are deemed restricted securities for purposes of the Securities Act. The recipients of securities in the transactions exempt under Section 4(2) or Regulation D of the Securities Act represented their intention to acquire the securities for investment purposes only and not with a view to or for sale in connection with any distribution thereof and appropriate legends were affixed to the stock certificates and instruments issued in such transactions.
 
Item 16.   Exhibits and Financial Data Schedules
 
(A) Exhibits
 
         
Exhibit
     
No.
   
Description of Exhibit
 
  *1.1     Form of Underwriting Agreement
  3.1     Restated Certificate of Incorporation of Ceres, Inc., as currently in effect
  *3.2     Form of Amended and Restated Certificate of Incorporation of Ceres, Inc. to be filed in connection with the consummation of this offering
  3.3     Amended and Restated Bylaws of Ceres, Inc., as currently in effect
  *3.4     Form of Amended and Restated Bylaws of Ceres, Inc. to be filed in connection with the consummation of this offering
  *4.1     Form of Stock Certificate
  *4.2     Warrant to Purchase Shares of Series E Preferred Stock issued to Silicon Valley Bank, dated August 16, 2004, as amended
  *4.3     Warrant to Purchase Shares of Common Stock issued to The Samuel Roberts Noble Foundation Inc., dated November 28, 2006
  *4.4     Warrant to Purchase Shares of Common Stock issued to The Texas A&M University System, dated July 18, 2008
  *4.5     Warrant to Purchase Shares of Series F Preferred Stock issued to Silicon Valley Bank, dated March 1, 2010
  4.6     Amended and Restated Investors’ Rights Agreement, dated June 25, 2010, by and among Ceres, Inc. and the stockholders named therein
  *5.1     Opinion of Shearman & Sterling LLP
  10.1     Ceres, Inc. 2000 Stock Option/Stock Issuance Plan, as amended


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Exhibit
     
No.
   
Description of Exhibit
 
  *10.2     Form of Stock Option Agreement under the Ceres, Inc. 2000 Stock Option/Stock Issuance Plan
  *10.3     Form of Stock Purchase Agreement under the Ceres, Inc. 2000 Stock Option/Stock Issuance Plan
  10.4     Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
  *10.5     Form of Stock Option Agreement under the Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
  *10.6     Form of Stock Purchase Agreement under the Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
  10.7     Restricted Stock Grant Agreement between J. Jefferson Gwyn and Ceres, Inc., dated December 22, 2008
  *10.8     Ceres, Inc. 2011 Equity Incentive Plan
  10.9     Agricultural Lease Agreement between John & Connie Giesenschlag and Ceres, Inc. dated April 1, 2008
  10.10     Ground Lease Agreement between John & Connie Giesenschlag and Ceres, Inc. dated April 1, 2008
  *10.11     Exclusive License Agreement between Cambridge University Technical Services, Ltd. and Ceres, Inc., dated November 1, 2001
  *10.12     Sponsored Research Agreement between The Texas Agricultural Experiment Station of The Texas A&M University System and Ceres, Inc., dated August 29, 2007, as amended
  *10.13     Intellectual Property Rights Agreement between The Texas Agricultural Experiment Station of The Texas A&M University System and Ceres, Inc., dated August 29, 2007
  *10.14     Material Transfer and Evaluation Agreement between The Texas A&M University System and Ceres, Inc., dated April 23, 2008
  *10.15     Line License Agreement between The Texas A&M University System and Ceres, Inc., dated October 16, 2009
  *10.16     Master Research Agreement between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated May 19, 2006
  *10.17     Evaluation, Production and License Agreement between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated May 19, 2006
  *10.18     License Agreement for NF/GA992 and NF/GA993 between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated December 1, 2008
  *10.19     License Agreement for NF/GA002 between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated September 1, 2009
  *10.20     Collaboration Agreement between the Institute of Biological, Environmental and Rural Sciences of Aberystwyth University and Ceres, Inc., dated April 1, 2007, as amended
  *10.21     Collaboration Agreement between Institute of Crop Sciences of the Chinese Academy of Agricultural Sciences and Ceres, Inc., dated November 15, 2007, as amended
  10.22     Loan and Security Agreement between Silicon Valley Bank and Ceres, Inc., dated January 29, 2010 and amendments thereto dated March 17, 2010 and August 10, 2010
  *10.23     Employment Agreement between Ceres, Inc. and Richard Hamilton, dated          , 2011
  *10.24     Employment Agreement between Ceres, Inc. and Paul Kuc, dated          , 2011
  *10.25     Employment Agreement between Ceres, Inc. and Michael Stephenson, dated          , 2011
  *10.26     Employment Agreement between Ceres, Inc. and J. Jefferson Gwyn, dated          , 2011
  *10.27     Employment Agreement between Ceres, Inc. and Roger Pennell, dated          , 2011
  *10.28     Exclusive Consulting Agreement between Ceres, Inc. and Robert Goldberg, dated January 1, 2006, and the amendments thereto dated November 17, 2006 and December 31, 2010

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Exhibit
     
No.
   
Description of Exhibit
 
  21.1     List of Subsidiaries
  23.1     Consent of KPMG LLP
  *23.2     Consent of Shearman & Sterling LLP (included in Exhibit 5.1)
  24.1     Power of Attorney (included on signature page)
 
 
* To be filed by amendment.
 
(B) Financial Statement Schedules
 
All schedules have been omitted because the information required to be presented in them is not applicable or is shown in the consolidated financial statements or related notes.
 
Item 17.   Undertakings
 
The undersigned registrant hereby undertakes to provide to the underwriters at the closing specified in the underwriting agreement certificates in such denominations and registered in such names as required by the underwriters to permit prompt delivery to each purchaser.
 
Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been informed that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
 
The undersigned registrant hereby undertakes that:
 
1. For purposes of determining any liability under the Securities Act, the information omitted from the form of prospectus filed as part of this Registration Statement in reliance upon Rule 430A and contained in a form of prospectus filed by the registrant pursuant to Rule 424(b)(1) or (4) or 497(h) under the Securities Act shall be deemed to be part of this Registration Statement as of the time it was declared effective.
 
2. For the purpose of determining any liability under the Securities Act, each post-effective amendment that contains a form of prospectus shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

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SIGNATURES
 
Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Thousand Oaks, State of California, on May 20, 2011.
 
CERES, INC.
 
  By: 
/s/  Richard Hamilton, Ph.D.
Richard Hamilton, Ph.D.
President and Chief Executive Officer
 
Each person whose signature appears below constitutes and appoints Richard Hamilton, Paul M. Kuc and Wilfriede van Assche, and each of them singly, his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement and any and all additional Registration Statements pursuant to Rule 462(b) of the Securities Act of 1933, as amended, and to file the same, with all exhibits thereto, and all other documents in connection therewith, with the Securities and Exchange Commission, granting unto each said attorney-in-fact and agent full power and authority to do and perform each and every act in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or either of them or their or his or her substitute or substitutes may lawfully do or cause to be done by virtue hereof.
 
Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities and on dates indicated.
 
             
Signature
 
Title
 
Date
 
         
/s/  Richard Hamilton, Ph.D.
     Richard Hamilton, Ph.D.
  President, Chief Executive Officer and Director
(Principal Executive Officer)
  May 20, 2011
         
/s/  Paul M. Kuc
     Paul M. Kuc
  Chief Financial Officer
(Principal Financial and Accounting Officer)
  May 20, 2011
         
/s/  Walter De Logi, Ph.D.
     Walter De Logi, Ph.D.
  Chairman of the Board of Directors   May 20, 2011
         
/s/  Pascal Brandys
     Pascal Brandys
  Director   May 20, 2011
         
/s/  Raymond Debbane
     Raymond Debbane
  Director   May 20, 2011
         
/s/  Ruth Devenyns
     Ruth Devenyns
  Director   May 20, 2011
         
/s/  Richard Flavell, Ph.D.
     Richard Flavell, Ph.D.
  Director   May 20, 2011


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Signature
 
Title
 
Date
 
         
/s/  Robert Goldberg, Ph.D.
     Robert Goldberg, Ph.D.
  Director   May 20, 2011
         
/s/  Thomas Kiley
     Thomas Kiley
  Director   May 20, 2011
         
/s/  David B. Krieger
     David B. Krieger
  Director   May 20, 2011
         
/s/  Edmund Olivier
     Edmund Olivier
  Director   May 20, 2011
         
/s/  Gerard Van Acker
     Gerard Van Acker
  Director   May 20, 2011


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EXHIBIT INDEX
 
         
Exhibit
     
No.
   
Description of Exhibit
 
  *1.1     Form of Underwriting Agreement
  3.1     Restated Certificate of Incorporation of Ceres, Inc., as currently in effect
  *3.2     Form of Amended and Restated Certificate of Incorporation of Ceres, Inc. to be filed in connection with the consummation of this offering
  3.3     Amended and Restated Bylaws of Ceres, Inc., as currently in effect
  *3.4     Form of Amended and Restated Bylaws of Ceres, Inc. to be filed in connection with the consummation of this offering
  *4.1     Form of Stock Certificate
  *4.2     Warrant to Purchase Shares of Series E Preferred Stock issued to Silicon Valley Bank, dated August 16, 2004, as amended
  *4.3     Warrant to Purchase Shares of Common Stock issued to The Samuel Roberts Noble Foundation Inc., dated November 28, 2006
  *4.4     Warrant to Purchase Shares of Common Stock issued to The Texas A&M University System, dated July 18, 2008
  *4.5     Warrant to Purchase Shares of Series F Preferred Stock issued to Silicon Valley Bank, dated March 1, 2010
  4.6     Amended and Restated Investors’ Rights Agreement, dated June 25, 2010, by and among Ceres, Inc. and the stockholders named therein
  *5.1     Opinion of Shearman & Sterling LLP
  10.1     Ceres, Inc. 2000 Stock Option/Stock Issuance Plan, as amended
  *10.2     Form of Stock Option Agreement under the Ceres, Inc. 2000 Stock Option/Stock Issuance Plan
  *10.3     Form of Stock Purchase Agreement under the Ceres, Inc. 2000 Stock Option/Stock Issuance Plan
  10.4     Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
  *10.5     Form of Stock Option Agreement under the Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
  *10.6     Form of Stock Purchase Agreement under the Ceres, Inc. 2010 Stock Option/Stock Issuance Plan
  10.7     Restricted Stock Grant Agreement between J. Jefferson Gwyn and Ceres, Inc., dated December 22, 2008
  *10.8     Ceres, Inc. 2011 Equity Incentive Plan
  10.9     Agricultural Lease Agreement between John & Connie Giesenschlag and Ceres, Inc., dated April 1, 2008
  10.10     Ground Lease Agreement between John & Connie Giesenschlag and Ceres, Inc., dated April 1, 2008
  *10.11     Exclusive License Agreement between Cambridge University Technical Services, Ltd. and Ceres, Inc., dated November 1, 2001
  *10.12     Sponsored Research Agreement between The Texas Agricultural Experiment Station of The Texas A&M University System and Ceres, Inc., dated August 29, 2007, as amended
  *10.13     Intellectual Property Rights Agreement between The Texas Agricultural Experiment Station of The Texas A&M University System and Ceres, Inc., dated August 29, 2007
  *10.14     Material Transfer and Evaluation Agreement between The Texas A&M University System and Ceres, Inc., dated April 23, 2008
  *10.15     Line License Agreement between The Texas A&M University System and Ceres, Inc., dated October 16, 2009
  *10.16     Master Research Agreement between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated May 19, 2006


Table of Contents

         
Exhibit
     
No.
   
Description of Exhibit
 
  *10.17     Evaluation, Production and License Agreement between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated May 19, 2006
  *10.18     License Agreement for NF/GA992 and NF/GA993 between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated December 1, 2008
  *10.19     License Agreement for NF/GA002 between The Samuel Roberts Noble Foundation, Inc. and Ceres, Inc., dated September 1, 2009
  *10.20     Collaboration Agreement between the Institute of Biological, Environmental and Rural Sciences of Aberystwyth University and Ceres, Inc., dated April 1, 2007, as amended
  *10.21     Collaboration Agreement between Institute of Crop Sciences of the Chinese Academy of Agricultural Sciences and Ceres, Inc., dated November 15, 2007, as amended
  10.22     Loan and Security Agreement between Silicon Valley Bank and Ceres, Inc., dated January 29, 2010 and amendments thereto dated March 17, 2010 and August 10, 2010
  *10.23     Employment Agreement between Ceres, Inc. and Richard Hamilton, dated          , 2011
  *10.24     Employment Agreement between Ceres, Inc. and Paul Kuc, dated          , 2011
  *10.25     Employment Agreement between Ceres, Inc. and Michael Stephenson, dated          , 2011
  *10.26     Employment Agreement between Ceres, Inc. and J. Jefferson Gwyn, dated          , 2011
  *10.27     Employment Agreement between Ceres, Inc. and Roger Pennell, dated          , 2011
  *10.28     Exclusive Consulting Agreement between Ceres, Inc. and Robert Goldberg, dated January 1, 2006, and, the amendments thereto dated November 17, 2006 and December 31, 2010
  21.1     List of Subsidiaries
  23.1     Consent of KPMG LLP
  *23.2     Consent of Shearman & Sterling LLP (included in Exhibit 5.1)
  24.1     Power of Attorney (included on signature page).
 
 
* To be filed by amendment.
 
(B) Financial Statement Schedules
 
All schedules have been omitted because the information required to be presented in them is not applicable or is shown in the consolidated financial statements or related notes.