0001493152-21-003697.txt : 20210212
0001493152-21-003697.hdr.sgml : 20210212
20210212171528
ACCESSION NUMBER: 0001493152-21-003697
CONFORMED SUBMISSION TYPE: 13F-HR
PUBLIC DOCUMENT COUNT: 2
CONFORMED PERIOD OF REPORT: 20201231
FILED AS OF DATE: 20210212
DATE AS OF CHANGE: 20210212
EFFECTIVENESS DATE: 20210212
FILER:
COMPANY DATA:
COMPANY CONFORMED NAME: Opaleye Management Inc.
CENTRAL INDEX KEY: 0001595855
IRS NUMBER: 205648796
STATE OF INCORPORATION: MA
FISCAL YEAR END: 1231
FILING VALUES:
FORM TYPE: 13F-HR
SEC ACT: 1934 Act
SEC FILE NUMBER: 028-15896
FILM NUMBER: 21629632
BUSINESS ADDRESS:
STREET 1: ONE BOSTON PLACE
STREET 2: SUITE 2600
CITY: BOSTON
STATE: MA
ZIP: 02108
BUSINESS PHONE: 617-904-9195
MAIL ADDRESS:
STREET 1: ONE BOSTON PLACE
STREET 2: SUITE 2600
CITY: BOSTON
STATE: MA
ZIP: 02108
13F-HR
1
primary_doc.xml
13F-HR
LIVE
false
true
false
0001595855
XXXXXXXX
12-31-2020
12-31-2020
false
Opaleye Management Inc.
One Boston Place
Suite 2600
Boston
MA
02108
13F HOLDINGS REPORT
028-15896
N
James Silverman
President
617-229-5085
/s/ James Silverman
Boston
MA
02-12-2021
0
59
765569
INFORMATION TABLE
2
infotable.xml
ACUTUS MEDICAL INC
COM
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21607
749990
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749990
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ADAMAS PHARMACEUTICALS INC
COM
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6442
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SH
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1487800
0
0
AKOUS INC
COM
00973J101
901
45459
SH
SOLE
45459
0
0
AMARIN CORP PLC
SPONSORED ADR NEW
023111206
1100
225000
SH
SOLE
225000
0
0
APTOSE BIOSCIENCES INC
COM NEW
03835T200
3504
800000
SH
SOLE
800000
0
0
AVEO BIOSCIENCES INC
COM NEW
053588307
339
58800
SH
SOLE
58800
0
0
BIOHAVEN PHARMACEUTICAL HLDG
COM
G11196105
9771
114000
SH
SOLE
114000
0
0
BIOLINERX LTD
SPONSORED ADS
09071M205
42
16667
SH
SOLE
16667
0
0
CARDIFF ONCOLOGY INC
COM
14147L108
29908
1662500
SH
SOLE
1662500
0
0
CATABASIS PHARMACEUTICALS INC
COM NEW
14875P206
402
187750
SH
SOLE
187750
0
0
CATALYST BIOSCIENCES INC
COM NEW
14888D208
939
148800
SH
SOLE
148800
0
0
CELLDEX THERAPEUTICS INC
COM NEW
15117B202
17380
992000
SH
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992000
0
0
CERECOR INC
COM
15671L109
6917
2620000
SH
SOLE
2620000
0
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CHEMOCENTRYX INC
COM
16383L106
21672
350000
SH
SOLE
350000
0
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CHIMERIX INC
COM
16934W106
19110
3956500
SH
SOLE
3956500
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CODEXIS INC
COM
192005106
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1400000
SH
SOLE
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0
CONCERT PHARMACEUTICALS INC
COM
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3211
254000
SH
SOLE
254000
0
0
CONTRAFECT CORP
COM NEW
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2222
440000
SH
SOLE
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0
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CYTOKINETICS INC
COM NEW
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12111
582800
SH
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DECIPHERA PHARMACEUTICALS IN
COM
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222000
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0
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EDAP TMS SA
SPONSORED ADR
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3399
657500
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657500
0
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EIDOS THERAPEUTICS INC
COM
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41520
315550
SH
SOLE
315550
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ESSA PHARMA INC
COM NEW
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3389
284050
SH
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284050
0
0
ETON PHARMACEUTICALS INC
COM
29772L108
32845
4040000
SH
SOLE
4040000
0
0
FIBROGEN INC
COM
31572Q808
5452
147000
SH
SOLE
147000
0
0
FIVE PRIME THERAPEUTICS INC
COM
33830X104
6496
381900
SH
SOLE
381900
0
0
FORTRESS BIOTECH INC
COM
34960Q109
12323
3887500
SH
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3887500
0
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FS DEV CORP
COM CL A
303020101
7748
704400
SH
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704400
0
0
FULCRUM THERAPEUTICS INC
COM
359616109
1034
88300
SH
SOLE
88300
0
0
HARROW HEALTH INC
COM
415858109
21029
3065416
SH
SOLE
3065416
0
0
INFINITY PHARMACEUTICALS INC
COM
45665G303
6724
3171800
SH
SOLE
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0
0
KALVISTA PHARMACEUTICALS INC
COM
483497103
8929
470203
SH
SOLE
470203
0
0
KEZAR LIFE SCIENCES INC
COM
49372L100
3696
708000
SH
SOLE
708000
0
0
KINIKSA PHARMACEUTICALS LTD
COM CL A
G5269C101
3960
224100
SH
SOLE
224100
0
0
LUMOS PHARMA INC
COM
55028X109
10045
281287
SH
SOLE
281287
0
0
MACROGENICS INC
COM
556099109
8472
370600
SH
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370600
0
0
MAGENTA THERAPEUTICS INC
COM
55910K108
375
47804
SH
SOLE
47804
0
0
MEI PHARMA INC
COM NEW
55279B202
4108
1556000
SH
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1556000
0
0
MERUS NV
COM
N5749R100
6188
353000
SH
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353000
0
0
MYOVANT SCIENCES LTD
COM
G637AM102
10487
682500
SH
SOLE
682500
0
0
NEOLEUKIN THERAPEUTICS INC
COM
64049K104
19547
1386300
SH
SOLE
1386300
0
0
OCULAR THERAPEUTIX INC
COM
67576A100
134758
6510000
SH
SOLE
6510000
0
0
OPTINOSE INC
COM
68404V100
1801
435000
SH
SOLE
435000
0
0
PRAXIS PRECISION MEDICINES INC
COM
74006W108
3489
63416
SH
SOLE
63416
0
0
PROTAGONIST THERAPEUTICS INC
COM
74366E102
7020
260000
SH
SOLE
260000
0
0
PROTARA THERAPEUTICS INC
COM STK
74365U107
61941
2558472
SH
SOLE
2558472
0
0
RHYTHM PHARMACEUTICALS INC
COM
76243J105
3419
115000
SH
SOLE
115000
0
0
SERES THERAPEUTICS
COM
81750R102
9804
335312
SH
SOLE
335312
0
0
SIERRA ONCOLOGY INC
COM NEW
82640U404
1208
75379
SH
SOLE
75379
0
0
SIO GENE THERAPIES INC
COM
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5560
2000000
SH
SOLE
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0
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STEREOTAXIS INC
COM NEW
85916J409
15379
3021436
SH
SOLE
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0
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SUTRO BIOPHARMA INC
COM
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6995
322200
SH
SOLE
322200
0
0
TELA BIO INC
COM
872381108
5490
365000
SH
SOLE
365000
0
0
TG THERAPEUTICS INC
COM
88322Q108
20158
387500
SH
SOLE
387500
0
0
TRACON PHARMACEUTICALS INC
COM NEW
89237H209
29465
2518371
SH
SOLE
2518371
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TRICIDA INC
COM
89610F101
6761
959000
SH
SOLE
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0
0
VAXCYTE
COM
92243G108
8906
335200
SH
SOLE
335200
0
0
VERASTEM INC
COM
92337C104
4761
2325000
SH
SOLE
2325000
0
0
XOMA CORP DEL
COM NEW
98419J206
20079
455000
SH
SOLE
455000
0
0