Exhibit 8.1

SUBSIDIARIES OF THE REGISTRANT

·State Good Group Limited, incorporated in the British Virgin Islands

·Master Luck Corporation, incorporated in Hong Kong, S.A.R.

·ChinaVax, incorporated in the Cayman Islands

·Pearl Ocean Holding Limited, incorporated in Samoa

·Kanda Biotech Holdings Limited, incorporated in the British Virgin Islands

·Simcere Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Nanjing Simcere Dongyuan Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Jiangsu Simcere Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Shanghai Simcere Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Jiangsu Simcere Pharmaceutical R&D Co., Ltd., incorporated in the People’s Republic of China

·Sichuan Zigong Yirong Industrial Co., Ltd., incorporated in the People’s Republic of China

·Hainan Qitian Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Shandong Simcere Medgenn Bio-Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Medgenn (Hong Kong) Co., Ltd., incorporated in Hong Kong, S.A.R.

·Jilin Boda Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Wuhu Simcere Zhong Ren Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Jiangsu Quanyi Biological Technology Stock Co., Ltd., incorporated in the People’s Republic of China

·Nanjing Xiangao Investments Management Co., Ltd., incorporated in the People’s Republic of China

·Jiangsu Simcere Vaxtec Bio-Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Shanghai Celgen Bio-Pharmaceutical Co., Ltd., incorporated in the People’s Republic of China

·Simcere of America Inc., incorporated in the State of Delaware

·Oy Simcere Europe Limited, incorporated in Republic of Finland

·Right Wealth Holdings Limited, incorporated in the British Virgin Islands

·Cosmo Key Limited, incorporated in the British Virgin Islands

·Nanjing Simcere Dongyuan Technology & Trade Co., Ltd, incorporated in the People’s Republic of China

·Shanghai Simcere Pharmaceutical R&D Co., Ltd, incorporated in the People’s Republic of China

·Beijing Simcere Pharmaceutical Investment Co., Ltd, incorporated in the People’s Republic of China

·Beijing XiangaoBio-Tech Co., Ltd, incorporated in the People’s Republic of China

·Beijing Xianjun Info-Tech Co., Ltd, incorporated in the People’s Republic of China