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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 LZ11jlF/aNbQY3ZcdontVICECTJiYEUwtGomqTiE7Szbk91YBe9ZCEqCjJz15bKq
 oJo0FRFqm0GFiGBgxRZNIw==

<SEC-DOCUMENT>0001344705-09-000018.txt : 20090611
<SEC-HEADER>0001344705-09-000018.hdr.sgml : 20090611
<ACCEPTANCE-DATETIME>20090611150652
ACCESSION NUMBER:		0001344705-09-000018
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20090610
FILED AS OF DATE:		20090611
DATE AS OF CHANGE:		20090611

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Salvatore Louis P
		CENTRAL INDEX KEY:			0001294561

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21833
		FILM NUMBER:		09886856

	MAIL ADDRESS:	
		STREET 1:		7 SYLVAN WAY
		CITY:			PARSIPPANY
		STATE:			NJ
		ZIP:			07054

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HELIOS MULTI-SECTOR HIGH INCOME FUND, INC.
		CENTRAL INDEX KEY:			0001343602
		IRS NUMBER:				204048379
		STATE OF INCORPORATION:			MD
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		HYPERION BROOKFIELD ASSET MANAGEMENT INC
		STREET 2:		3 WFC, 200 VESEY STREET, 10TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10281-1010
		BUSINESS PHONE:		2125498328

	MAIL ADDRESS:	
		STREET 1:		HYPERION BROOKFIELD ASSET MANAGEMENT INC
		STREET 2:		3 WFC, 200 VESEY STREET, 10TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10281-1010

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Helios Multi-Sector High Income Fund Inc
		DATE OF NAME CHANGE:	20090107

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	RMK Multi-Sector High Income Fund Inc
		DATE OF NAME CHANGE:	20051104
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2009-06-10</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001343602</issuerCik>
        <issuerName>HELIOS MULTI-SECTOR HIGH INCOME FUND, INC.</issuerName>
        <issuerTradingSymbol>HMH</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001294561</rptOwnerCik>
            <rptOwnerName>Salvatore Louis P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O HYPERION BROOKFIELD ASSET MGMT., INC</rptOwnerStreet1>
            <rptOwnerStreet2>3 WFC, 200 VESEY STREET, 10TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10281-1010</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2009-06-10</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>12000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.95</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>12000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Jonathan C. Tyras, on behalf of Louis P. Salvatore</signatureName>
        <signatureDate>2009-06-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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