SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
BUECHLER KENNETH F
(Last) (First) (Middle)
BIOSITE INCORPORATED
11030 ROSELLE STREET
(Street)
SAN DIEGO CA 92121
(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
BIOSITE INC [ BSTE ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
Pres. & Chief Scientific Offic
3. Date of Earliest Transaction (Month/Day/Year)
02/03/2005
4. If Amendment, Date of Original Filed (Month/Day/Year)
 6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/07/2005 M 1,536 A $10 2,757 D
Common Stock 02/07/2005 S 1,536 D $63 1,221 D
Common Stock 02/07/2005 M 8,364 A $24.95 9,585 D
Common Stock 02/07/2005 S 8,364 D $63 1,221 D
Common Stock 281,147 I family trust
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $10 02/03/2005 M 614 06/09/1999(1) 06/09/2009 Common Stock 614 $61.6586 1,536 D
Non-Qualified Stock Option (right to buy) $10 02/07/2005 M 1,536 06/09/1999(1) 06/09/2009 Common Stock 1,536 $63 0 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 2,000 06/18/2002(1) 06/18/2012 Common Stock 2,000 $61.547 50,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 1,500 06/18/2002(1) 06/18/2012 Common Stock 1,500 $61.5081 48,742 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 1,000 06/18/2002(1) 06/18/2012 Common Stock 1,000 $61.508 47,742 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.512 47,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.5 46,742 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.728 46,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 1,000 06/18/2002(1) 06/18/2012 Common Stock 1,000 $61.68 45,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.66 44,742 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.658 44,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.662 43,742 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.636 43,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.576 42,742 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 500 06/18/2002(1) 06/18/2012 Common Stock 500 $61.522 42,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/04/2005 M 10,000 06/18/2002(1) 06/18/2012 Common Stock 10,000 $62 32,242 D
Non-Qualified Stock Option (right to buy) $24.95 02/07/2005 M 8,364 06/18/2002(1) 06/18/2012 Common Stock 8,364 $63 23,878 D
Explanation of Responses:
1. Option vests daily over a four-year period commencing on the date of grant, except that no options are exercisable for the first six months after the date of grant.
By: Robyn Shutak For: Kenneth Buechler 02/07/2005
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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