SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* Aldagen Holdings, LLC (Last) (First) (Middle) C/O THOMAS A. ALLEN, ESQ. 4101 LAKE BOONE TRAIL, STE 300 (Street) RALEIGH NC 27607 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Nuo Therapeutics, Inc. [ NUOT ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) X Other (specify below) May be part of a 13(d) Group
	3. Date of Earliest Transaction (Month/Day/Year) 06/13/2013
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/13/2013		J(1)		105,300	D	$0	11,936,265	D(2)
Common Stock	11/11/2014		J(3)		1,270,000	A	$1.18(3)	13,206,265	D(2)
Common Stock	12/30/2014		S		1,200	D	$0.35	13,205,065	D(2)
Common Stock	01/09/2015		S		15,850	D	$0.35	13,189,215	D(2)
Common Stock								108,830	I	See Footnote 4(4)
Common Stock								157,276	I	See Footnote 5(5)
Common Stock								175,533	I	See Footnote 6(6)
Common Stock								429,404	I	See Footnote 7(7)
Common Stock								60,494	I	See Footnote 8(8)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Warrant (right to buy)	$0.75							02/22/2013	02/21/2018	Common Stock	15,616		15,616	I	See Footnote 4(4)
Warrant (right to buy)	$0.75							02/22/2013	02/21/2018	Common Stock	22,567		22,567	I	See Footnote 5(5)
Warrant (right to buy)	$0.75							02/22/2013	02/21/2018	Common Stock	63,636		63,636	I	See Footnote 6(6)
Warrant (right to buy)	$0.75							02/22/2013	02/21/2018	Common Stock	63,636		63,636	I	See Footnote 7(7)
Warrant (right to buy)	$0.75							02/22/2013	02/21/2018	Common Stock	12,727		12,727	I	See Footnote 8(8)

1. Name and Address of Reporting Person* Aldagen Holdings, LLC (Last) (First) (Middle) C/O THOMAS A. ALLEN, ESQ. 4101 LAKE BOONE TRAIL, STE 300 (Street) RALEIGH NC 27607 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) X Other (specify below) May be part of a 13(d) Group

1. Name and Address of Reporting Person* Clark B. Jefferson (Last) (First) (Middle) C/O THOMAS A. ALLEN, ESQ. 4101 LAKE BOONE TRAIL, SUITE 300 (Street) RALEIGH NC 27607 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) X Other (specify below) May be part of a 13(d) Group

1. Name and Address of Reporting Person* Brooke William W (Last) (First) (Middle) C/O THOMAS A. ALLEN, ESQ. 4101 LAKE BOONE TRAIL, SUITE 300 (Street) RALEIGH NC 27607 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) X Other (specify below) May be part of a 13(d) Group

Explanation of Responses:

1. Distribution by Aldagen Holdings, LLC ("Holdings") to independent third party in exchange for professional services rendered.

2. The reportable securities are owned directly by Holdings. The shares directly held by Holdings are indirectly held by the individual managing members of Holdings (each a "Holdings Managing Member" and collectively, the "Holdings Managing Members"). The Holdings Managing Members are B. Jefferson Clark and William Brooke. The Holdings Managing Members may share voting and dispositive power over the shares directly held by Holdings. Each Holdings Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Holdings Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein.

3. On November 11, 2014, Holdings became entitled to receive 1,270,000 shares of Issuer's common stock pursuant to a post-closing milestone provision in the Exchange and Purchase Agreement (as amended, the "Agreement") among the Issuer, Aldagen, Inc. and Holdings, dated February 8, 2012, as amended by the Second Amendment dated November 11, 2014 (the "Second Amendment"). The Agreement provided that Holdings receive additional shares, for no additional consideration, if Issuer achieved specified research milestones. Pursuant to the Second Amendment, Holdings agreed to receive 1,270,000 shares in full satisfaction of all obligations Issuer held pursuant to the post-closing milestone provisions in the Agreement. The price per share set forth in the Agreement is $1.1817, as agreed upon by the parties to the Agreement on February 8, 2012. Holdings's right to receive additional shares became fixed and irrevocable on November 11, 2014, the effective date of the Second Amendment.

4. The reportable securities are owned directly by Harbinger/Aurora Venture Fund, L.L.C. ("Harbinger Venture Fund"), and indirectly by Harbinger/Aurora Ventures, L.L.C. ("Harbinger Ventures LLC"), as the managing member of Harbinger Venture Fund. Mr. Clark is the president of Harbinger Ventures LLC and a managing member of Holdings. Harbinger Ventures LLC and Harbinger Venture Fund may share voting and dispositive power over the shares directly held by Harbinger Venture Fund. Mr. Clark disclaims beneficial ownership of these securities and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein.

5. The reportable securities are owned directly by Harbinger/Aurora QP Venture Fund, L.L.C. ("Harbinger QP"), and indirectly by Harbinger Ventures LLC, as the managing member of Harbinger QP. Harbinger Ventures LLC and Harbinger QP may share voting and dispositive power over the shares directly held by Harbinger QP. Mr. Clark disclaims beneficial ownership of these securities and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein.

6. The reportable securities are owned directly by Harbert Venture Partners (Annex Fund), L.L.C. ("Harbert Venture Fund"), indirectly by Harbert Venture Partners MM, LLC ("Harbert Venture Partners LLC"), as the sole managing member of Harbert Venture Fund, and indirectly by Will Brooke, as managing partner of Harbert Venture Partners LLC. Mr. Brooke is a managing member of Holdings. Harbert Venture Fund, Harbert Venture Partners LLC, and Mr. Brooke may share voting and dispositive power over the shares directly held by Harbert Venture Fund. Mr. Brooke disclaims beneficial ownership of these securities and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein.

7. The reportable securities are owned directly by ALD Co-Investor, LLC ("ALD"), indirectly by Harbert Venture Partners LLC, as the sole managing member of ALD, and indirectly by Mr. Brooke, as managing partner of Harbert Venture Partners LLC. ALD, Harbert Venture Partners LLC, and Mr. Brooke may share voting and dispositive power over the shares directly held by ALD. Mr. Brooke disclaims beneficial ownership of these securities and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein.

8. The reportable securities are owned directly by Aurora Enrichment Fund, L.L.C. ("Aurora"), and indirectly by Aurora Enrichment Management Company, L.L.C. ("Aurora Management Co"), as the managing member of Aurora, and each of the individual managing members of Aurora Management Co. The individual managing members (each an "Aurora Manager" and collectively, the "Aurora Managers") of Aurora Management Co are Messrs. Clark and Albert. Mr. Clark is the manager of Aurora Management Co and a managing member of Holdings. Aurora Management Co, Aurora, and the Aurora Managers may share voting and dispositive power over the shares directly held by Aurora. Each Aurora Manager disclaims beneficial ownership of these securities and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein.

	/s/ Thomas A. Allen, attorney-in-fact for Aldagen Holdings, LLC	03/12/2015
	/s/ Thomas A. Allen, attorney-in-fact for William W. Brooke	03/12/2015
	/s/ Thomas A. Allen, attorney-in-fact for B. Jefferson Clark	03/12/2015
	** Signature of Reporting Person	Date
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