Exhibit 99.6

NORFOLK SOUTHERN CORPORATION

OFFER TO EXCHANGE

$749,997,000 AGGREGATE PRINCIPAL AMOUNT OF

3.942% NOTES DUE 2047 (CUSIP NOS. 655844 BW7 AND U65584 AF8)

FOR

$749,997,000 AGGREGATE PRINCIPAL AMOUNT OF

3.942% NOTES DUE 2047 (CUSIP NO. 655844 BX5)

THAT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933,

AS AMENDED, PURSUANT TO THE PROSPECTUS, DATED                    , 2018

To Our Clients:

Enclosed for your consideration is a Prospectus, dated                    , 2018 (the “Prospectus”), and the related Letter of Transmittal (the “Letter of Transmittal”), relating to the offer of Norfolk Southern Corporation (the “Company”) to exchange (the “Exchange Offer”) its 3.942% Notes due 2047 that have been registered under the Securities Act of 1933, as amended, for its outstanding 3.942% Notes due 2047 (the “Original Notes”), upon the terms and subject to the conditions described in the Prospectus and the Letter of Transmittal. The Exchange Offer is being made in order to satisfy certain obligations of the Company contained in the Registration Rights Agreement, dated as of November 16, 2017, among the Company, as issuer, and the dealer manager named therein.

This material is being forwarded to you as the beneficial owner of the Original Notes held by us for your account but not registered in your name. A TENDER OF SUCH ORIGINAL NOTES MAY ONLY BE MADE BY US AS THE HOLDER OF RECORD AND PURSUANT TO YOUR INSTRUCTIONS.

Accordingly, we request instructions as to whether you wish us to tender on your behalf the Original Notes held by us for your account, pursuant to the terms and conditions set forth in the enclosed Prospectus and Letter of Transmittal.

Your instructions should be forwarded to us as promptly as possible in order to permit us to tender the Original Notes on your behalf in accordance with the provisions of the Exchange Offer. The Exchange Offer will expire at 5:00 p.m., New York City time, on                    , 2018, unless extended by the Company. Any Original Notes tendered pursuant to the Exchange Offer may be withdrawn at any time prior to 5:00 p.m., New York City time, on the expiration date.

Your attention is directed to the following:

1. The Exchange Offer is for any and all Original Notes.

2. The Exchange Offer is subject to certain conditions set forth in the Prospectus in the section captioned “The Exchange Offer—Conditions to the Exchange Offer.”

3. Any transfer taxes incident to the transfer of Original Notes from the holder to the Company will be paid by the Company, except as otherwise provided in the Instructions in the Letter of Transmittal.

4. The Exchange Offer expires at 5:00 p.m., New York City time, on                    , 2018, unless extended by the Company.

If you wish to have us tender your Original Notes, please so instruct us by completing, executing and returning to us the instruction form on the back of this letter. THE LETTER OF TRANSMITTAL IS FURNISHED TO YOU FOR INFORMATION ONLY AND MAY NOT BE USED DIRECTLY BY YOU TO TENDER ORIGINAL NOTES.

INSTRUCTIONS WITH RESPECT TO

THE EXCHANGE OFFER

The undersigned acknowledge(s) receipt of your letter and the enclosed material referred to therein relating to the Exchange Offer made by Norfolk Southern Corporation with respect to its Original Notes.

This will instruct you to tender the Original Notes held by you for the account of the undersigned, upon and subject to the terms and conditions set forth in the Prospectus and the related Letter of Transmittal.

The undersigned expressly agrees to be bound by the enclosed Letter of Transmittal and that such Letter of Transmittal may be enforced against the undersigned.

☐     Please tender the Original Notes held by you for my account as indicated below:

3.942% Notes due 2047

$    

(Aggregate Principal Amount of Original Notes)

☐     Please do not tender any Original Notes held by you for my account.                    

Dated:                                       , 2018

Signature(s):  

Print Name(s) here:  

Print Address(es):  

Area Code and Telephone Number(s):  

Tax Identification or Social Security Number(s):  

None of the Original Notes held by us for your account will be tendered unless we receive written instructions from you to do so. Unless a specific contrary instruction is given in the space provided, your signature(s) hereon shall constitute an instruction to us to tender all the Original Notes held by us for your account.